Abstract: An injection locked magnetron microwave generator with a recycle of spurious energy, relating to a microwave power source, includes a frequency selective reflector for recycling the spurious energy of a magnetron and satisfies locking requirements of an output frequency of a high-output-power magnetron with a low-power injection signal. The microwave generator includes n magnetrons and n locking devices, n?1. The locking devices inject locking signals into the corresponding magnetrons. The n locking devices are connected with a microwave source. Output terminals of the magnetrons are connected with corresponding frequency selective reflectors for reflecting the spurious microwave signals outputted by the magnetrons back to the magnetrons. The microwave generator, with a simple structure, effectively recycles the spurious energy outputted by the magnetrons, and reduces the power of the injection signal and costs of the microwave source and the overall microwave generator.

Abstract: A pneumatic fracturing method for exploiting shale gas, the method including: 1) applying a compressed gas for a first period of time at a first pressure to a shale formation; 2) applying the compressed gas for a second period of time at a second pressure to the shale formation; and 3) repeating steps 1) and 2) to produce fissures in the shale formation. A temperature of the compressed gas is at least 80° C. A maximum pressure of the compressed gas is at least 25 megapascal, and a minimum pressure of the compressed gas is between ¼ and ? of the maximum pressure.

Abstract: The present invention relates to the field of genetic engineering drugs, particularly to a novel B cell activating factor (BAFF) antagonist and use thereof. The technical problem to be solved by the invention is to find a new and effective selection for the prevention and treatment of autoimmune diseases. The B cell activating factor receptor antagonist is mainly obtained by the fusion of the domain 2 binding BAFF in TACI receptor and the domain binding BAFF in Br3 receptor, and it also can be fused with a Fc segment of IgG1 to obtain a new fusion protein molecule. Experiments indicate that said new fusion protein molecule has the function of BAFF antagonist, which can treat the autoimmune diseases, and supply a new and effective selection for the prevention and treatment of the autoimmune diseases.

Abstract: Hydroxy acid compound of substituted phenyl ester, preparation method and medical use thereof are provided. The title compound is shown in formula (I), Y?C1-4 straight carbon chain. The compound can release 2,6-diisopropylphenol rapidly under the action of enzymes in vivo, which has sedative, hypnotic and/or anesthetic effect. By protecting the hydroxyl group of 2, 6-diisopropylphenol in compound of formula (I), the first-pass metabolic activity of 2, 6-diisopropylphenol is reduced, so that the synthetic compound can be used for sedation, hypnosis, and/or anesthesia.

Abstract: Phosphate ester compound of hydroxy acid substituted phenyl ester, preparation method and medical use thereof are provided. The title compound is shown in formula (I), in which Y?C1-4 straight carbon chain, M1 and/or M2=H, alkali metal ion, protonated amine or protonated amino acid. The compound has good water solubility and high stability in its aqueous solution, and it can release 2,6-diisopropylphenol rapidly under the action of enzymes in vivo, which has the effects of sedation, hypnosis and/or anesthesia. By protecting hydroxyl of 2,6-diisopropylphenol in compound of formula (I), the first-pass metabolic activity of 2,6-diisopropylphenol is reduced, so that the synthetic compound can be used for sedation, hypnosis and/or anesthesia.

Abstract: Use of low dose streptozocin in the preparation of an animal model for screening drugs for treatment of antoimmune type 1 diabetes is disclosed, in which streptozocin is administrated intravenously at a dose of 15-30 mg/kg per time for 5 days and administrated again on the 7th day and 14th day after last time of offering drug. A method for preparing rhesus monkey model of autoimmune type 1 diabetes and autoimmune type 1 diabetes animal model obtained are also disclosed.

Abstract: Arylamino purine derivatives represented by formula I and their preparation method are disclosed, wherein each substituent is defined as in the description. The derivatives have an inhibitory effect on non-small cell lung cancer with deletion mutation of exon 19 or L858R point mutation of exon 21 in epidermal growth factor receptor (EGFR).

Abstract: The present invention relates to a new type of oil displacement agent and the process for preparing the same. The oil displacement agent is formed of a polyacrylamide-based polymer characterized by a partly crosslinked and partly branched structure, wherein said polyacrylamide-based polymer is obtained by aqueous copolymerization of acrylamide and N,N-dimethylaminoethyl methacrylate as a functional monomer, in the presence of a redox initiator system.

Abstract: An aerated swirling vertical shaft with double volute chambers comprises an upper volute chamber (2) and a first shrinking section (3) beneath the upper volute chamber (2), a venting passage (4) outside the upper volute chamber (2), a vertical shaft section (7) beneath the first shrinking section (3), as well as an aerated lower volute chamber (5) and a second shrinking section (6) communicated with the aerated lower volute chamber (5) between the first shrinking section (3) and the vertical shaft section (7), wherein the upper end of the aerated lower volute chamber (5) is connected with the first shrinking section (3), the lower end of the second shrinking section (6) is connected with the vertical shaft section (7); the upper end of the venting passage (4) is communicated with the atmosphere and the lower end is communicated with the aerated lower volute chamber (5).

Abstract: A method for building an underground storehouse by dissolving limestone with carbon dioxide, the method comprising the following steps: a.) drilling two wells extending from the ground surface (1) to a limestone layer (2), building a channel (5) allowing the two wells to communicate, and installing casing pipes (3, 4) respectively in the two wells; b.) introducing CO2 gas having at least 1 MPa of pressure into a CO2 absorbing solution having the same pressure to form a CO2 solution, flowing the CO2 solution into underground via the casing pipe (3) to react with the limestone to form a calcium bicarbonate solution, forming a cavern in the meanwhile, and discharging the calcium bicarbonate solution via the other casing pipe (4); c.) decompressing the discharged calcium bicarbonate solution to decompose the calcium bicarbonate contained in the solution into CO2, water and calcium carbonate, and recycling the separated CO2 absorption solution and the CO2; repeating steps b.) and c.

Abstract: The present invention relates to millepachine ((E)-1-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-(4-methoxyphenyl)prop-2-en-1-one) and its analogues. The present invention provides methods for preparing these compounds, pharmaceutical compositions including these compounds, and methods of treating diseases utilizing pharmaceutical compositions including these compounds.

Abstract: A universal multipurpose sensor fixing device comprises a radial positioning mechanism, supporting mechanisms, bases, acoustic emission test sensor mounting mechanisms, and parallelism adjusting members. Each supporting mechanism includes a main arm and an auxiliary arm having one end connected to the main arm and a ball head on the other end. A parallelism adjusting member mounting mechanism is provided at the joint of the main arm and the auxiliary arm. The main arms are respectively connected to the two free ends of the radial positioning mechanism to position the auxiliary arms at the inner sides of the main arms, arranged axis symmetrically with respect to the central line of the radial positioning mechanism. The ball heads of the two auxiliary arms are located within spherical holes of the bases to form universal revolute pairs. A set of acoustic emission test sensor mounting mechanisms are mounted at each base.

Abstract: A multipurpose sensor fixing device includes a radial positioning mechanism, a supporting mechanism, a base, a mounting mechanism, and a parallelism adjusting member. The supporting mechanism comprises a main supporting arm and an auxiliary supporting arm, with one end of the auxiliary supporting arm connected to the main supporting arm and the other end comprising kink shaft members. The main supporting arm is connected to an end of the radial positioning mechanism to locate the auxiliary supporting arm at the inner side of the main supporting arm. The kink shaft member of the auxiliary supporting arm is inserted into a plughole of the base to form a revolute pair with the auxiliary supporting arm. The mounting mechanism is mounted at the base. The parallelism adjusting member is mounted on the main supporting arm.

Abstract: Benzothiazinethione derivatives of formula (I), their preparative methods and uses are provided. Benzothiazinethione derivatives of the invention have significant effect of inhibiting Mycobacterium tuberculosis.

Abstract: A circular common-path point diffraction interference wavefront sensor includes an optical matching system, a beam-splitter, a first reflection mirror, a second reflection mirror, a first Fourier lens, a second Fourier lens, a charge-coupled device (CCD) detector, a computer system, and a two-pinhole mask having a reference pinhole and a testing window and placed at a confocal plane of the first Fourier lens and the second Fourier lens. A testing beam is divided into two beams through the beam-splitter. One beam makes the pinhole diffraction by the reference pinhole, thereby producing the approximately ideal plane wave as the reference wave. Another beam passes through the testing window almost without any attenuation as the signal wave. The spatially linear carrier frequency is introduced by adjusting the tilt angle of the beam-splitter. The present invention is adapted for all kinds of dynamic and static detection field of wavefront phase.

Abstract: Disclosed herein are the methods to improve the electrical conductivity for micro-moulded plastic parts containing carbon nanotubes. The polymer/carbon nanotubes composites suitable for polymer micromoulding including 80˜99.95 wt % of a polymer pellet or powder, 0-2 wt % of antioxidant, 0-2 wt % of dispersant agent and 0.05-20 wt % of carbon nanotube with a diameter 0.5-200 nm and a length of 200 nm-20 ?m are firstly prepared through melt extrusion. The plastic microparts are prepared by micromoulding of the polymer/carbon nanotubes composites including micro extrusion, micro injection and hot embossing at optimized processing conditions and then are subject to a post thermal treatment to enhance the electrical conductivity. The post thermal treatment methods include electric heating, microwave, infrared or plasma heating.

Abstract: An aerated swirling vertical shaft with double volute chambers comprises an upper volute chamber (2) and a first shrinking section (3) beneath the upper volute chamber (2), a venting passage (4) outside the upper volute chamber (2), a vertical shaft section (7) beneath the first shrinking section (3), as well as an aerated lower volute chamber (5) and a second shrinking section (6) communicated with the aerated lower volute chamber (5) between the first shrinking section (3) and the vertical shaft section (7), wherein the upper end of the aerated lower volute chamber (5) is connected with the first shrinking section (3), the lower end of the second shrinking section (6) is connected with the vertical shaft section (7); the upper end of the venting passage (4) is communicated with the atmosphere and the lower end is communicated with the aerated lower volute chamber (5).

Abstract: Use of low dose streptozocin in the preparation of an animal model for screening drugs for treatment of antoimmune type 1 diabetes is disclosed, in which streptozocin is administrated intravenously at a dose of 15-30 mg/kg per time for 5 days and administrated again on the 7th day and 14th day after last time of offering drug. A method for preparing rhesus monkey model of autoimmune type 1 diabetes and autoimmune type 1 diabetes animal model obtained are also disclosed.

Abstract: The present invention relates to the field of genetic engineering drugs, particularly to a novel B cell activating factor (BAFF) antagonist and use thereof. The technical problem to be solved by the invention is to find a new and effective selection for the prevention and treatment of autoimmune diseases. The B cell activating factor receptor antagonist is mainly obtained by the fusion of the domain 2 binding BAFF in TACI receptor and the domain binding BAFF in Br3 receptor, and it also can be fused with a Fc segment of IgG1 to obtain a new fusion protein molecule. Experiments indicate that said new fusion protein molecule has the function of BAFF antagonist, which can treat the autoimmune diseases, and supply a new and effective selection for the prevention and treatment of the autoimmune diseases.

Abstract: Phosphate ester compound of hydroxy acid substituted phenyl ester, preparation method and medical use thereof are provided. The title compound is shown in formula (I), in which Y=C1-4 straight carbon chain, M1 and/or M2=H, alkali metal ion, protonated amine or protonated amino acid. The compound has good water solubility and high stability in its aqueous solution, and it can release 2,6-diisopropylphenol rapidly under the action of enzymes in vivo, which has the effects of sedation, hypnosis and/or anesthesia. By protecting hydroxyl of 2,6-diisopropylphenol in compound of formula (I), the first-pass metabolic activity of 2,6-diisopropylphenol is reduced, so that the synthetic compound can be used for sedation, hypnosis and/or anesthesia.