Abstract: To increase the signal-to-noise ratio for displacements used to estimate the shear speed in patient tissue, constructive interference from multiple shear waves is used. By transmitting acoustic radiation force impulses focused at different locations, the resulting shear waves may constructively interfere within a region of interest. This constructive interference causes a greater amplitude of displacement. The location of this more easily detected greater interference and the difference in time of the transmitted acoustic radiation force impulses are used to estimate the shear wave speed for the tissue.

Abstract: A system, apparatus, and method for transferring chemical solutions and synthesizing a tracer. For transferring chemical solutions, the system comprises a primary container; a secondary container; a first line in communication with the primary container and the secondary container. The first line facilitates the flow of gas and/or liquid between the primary container and the secondary container. A valve located upstream of the secondary container and downstream of the primary container regulates flow within the first line; a second line in communication with the secondary container. For synthesizing a tracer, the system includes a source of a solution having a radionuclide. A first container has a tracer precursor and is in communication with the source of solution.

Abstract: For Doppler imaging in ultrasound, a single parameter is formed from both power and velocity. In any combination function, a derivative of velocity and/or velocity are combined with power. The resulting value is used to look-up a color from a one-dimensional color map.

Abstract: A heart rate monitor provides a pulse or heartbeat, but without the on-going or continuous phase signal of ECG and/or with a delay relative to the actual heartbeat. For phase determination in echocardiography, the heartbeat from the heart rate monitor is used to assist in identification of phase from acquired ultrasound data. Rather than relying on just ECG or just image processing, the worn or handheld heart rate monitor is used to simplify the image process-based identification of phase.

Abstract: Cross-calibration is provided for functional imaging. In PET or SPECT, the inaccuracies from the dose and detector sensitivity may be reduced or removed in both activity concentration and uptake. By using measures from both the radiotracer for the patient and factory calibrated sources, the variability due to dose may be removed. In SPECT, a measurement of system specific sensitivity to a factory calibrated point source is used to improve the accuracy of uptake values, not just activity concentration.

Abstract: A system and method includes acquisition of a plurality of non-attenuation-corrected volumes, each of the non-attenuation-corrected volumes based on a respective one of a plurality of sets of two-dimensional emission data, acquisition of a plurality of attenuation coefficient maps, each of the plurality of attenuation coefficient maps corresponding to a respective one of the plurality of sets of two-dimensional emission data, training of a convolutional network to generate a generated attenuation coefficient map from an input image volume, the training based on the plurality of non-attenuation-corrected volumes and respective ones of the plurality of attenuation coefficient maps, and output of trained kernels of the trained convolutional network to an emission imaging system.

Abstract: For acoustic radiation force ultrasound imaging, multiple displacement profiles for a given location are acquired. Physiological and/or transducer axial and/or lateral motion are accounted for using the displacements from the different acoustic radiation force impulses. For axial motion, a difference between the displacements of the different profiles provides information about motion during displacement at the location caused by just the undesired motion. A more accurate estimate of the undesired motion for removing from the displacement profile is provided. For lateral motion, the displacement profiles are obtained using waves traveling from different directions relative to the given location. An average of velocities estimated from the different profiles removes undesired lateral motion.

Abstract: To reduce speckle is spectral Doppler imaging, any oversampling relative to the velocity scale is used to create different data sets for the location at a given time. The different data sets have at least partially independent noise. Spectra are estimated from the different data sets and the resulting spectra combined into a spectrum with less speckle. To improve signal-to-noise ratio, the samples acquired for a given velocity scale are band-limited into different narrower bands. The portion of the spectrum estimated for each narrow band has a higher signal-to-noise ratio than a spectrum estimated for the entire band. The parts of the spectrum estimated for the different narrow bands are stitched together to provide a spectrum for the entire band with greater signal-to-noise ratio. In another approach, the user may input a narrow band relative to the velocity scale so that the corresponding part of the spectrum is provided with greater signal-to-noise ratio.

Abstract: Coherent combination of ultrasound data for collinear receive beams adapts to the ultrasound data. Beam-to-beam coherence metrics, such as correlation coefficient and/or phase change or functions of these parameters, are used to adapt weighting of the ultrasound data for the receive beams prior to combination or to adapt the results of the combination.

Abstract: Line artifact reduction is provided in multi-beam scanning for Doppler imaging. An analytic solution uses estimated velocities for collocated receive scan lines from different transmit beams to reduce or remove the biases caused by multi-beam receive. For each location, a line or curve is fit to the estimated velocities as a function of distance of the transmit scan lines to the location. The velocity at an intercept of this line with the distance of zero (intercept with the origin) indicates the unbiased velocity. This approach allows a solution even where all of the velocity estimates have a bias with the same sign, such as due to the location being on a same side of the different transmit scan lines.

Abstract: A detector, includes a plurality of photomultiplier tubes each having an anode configured to generate an anode output signal and a frequency domain detector interface including a plurality of frequency domain coupling circuits. Each of the plurality of frequency domain coupling circuits is configured to receive the anode output signal from one of the plurality of photomultiplier tubes and pickoff one of a high-frequency component or a low-frequency component. Each of the plurality of frequency domain coupling circuits is further configured to generate a pass-through signal comprising a first of the high-frequency component or the low-frequency component.

Abstract: Methods and systems for accelerated Phase-contrast magnetic resonance imaging (PC-MRI). The technique is based on Bayesian inference and provides for fast computation via an approximate message passing algorithm. The Bayesian formulation allows modeling and exploitation of the statistical relationships across space, time, and encodings in order to achieve reproducible estimation of flow from highly undersampled data.

Abstract: Systems and methods for configuring a radiation detector are provided. A first event is detected at a first scintillator crystal of a first detector unit. A second coincident event is detected at a second scintillator crystal of a second detector unit adjacent to the first detector unit. Operating parameters are calculated for the first detector unit based on the coincident events.

Abstract: Shear wave characteristics are estimated from analytic data. Measures of displacement are converted into complex representations. The magnitude and/or phase components of the complex representation may be used for estimating various characteristics, such as velocity, center frequency, attenuation, shear modulus, or shear viscosity. The zero-phase of the phase component represents an occurrence of the shear wave at that location.

Abstract: For estimating attenuation in ultrasound imaging, displacements at different locations along an acoustic radiation force impulse (ARFI) beam are used measured. The on-axis displacements and displacements from a phantom using a same ARFI focus as a reference are used to cancel out focusing effects. A single ARFI beam may be used to estimate the attenuation for a location.

Abstract: Pose of a probe is detected in x-ray medical imaging. Since the TEE probe is inserted through the esophagus of a patient, the pose is limited to being within the esophagus. The path of the esophagus is determined from medical imaging prior to the intervention. During the intervention, the location in 2D is found from one x-ray image at a given time. The 3D probe location is provided by assigning the depth of the esophagus at that 2D location to be the depth of the probe. A single x-ray image may be used to determine the probe location in 3D, allowing for real-time pose determination without requiring space to rotate a C-arm during the intervention.

Abstract: For multidimensional transducer array interconnection, circuit boards with electronics are stacked to form a surface for connection with the array. The surface of the circuit boards for connecting with the transducer array is metalized and diced. Rather than relying on small exposed traces, larger contact pads are formed by metalizing the surface and then dicing the surface. This forms an array of contact pads for connecting with the z-axis or other connectors for elements of the multidimensional transducer array.

Abstract: In beta emission imaging, magnetic lensing allows a lower resolution detector to detect the spatial distribution of emissions at a higher resolution. The sample is placed in a magnetic field with field lines at a given density, and the detector is placed away from the sample where the magnet field lines diverge, resulting in a lesser density. Since the beta emissions travel along the field lines, the divergence of the field lines from the sample to the detector result in lensing or magnification. Using positron attenuation tomography to detect annihilation in the detector allows for correction due to self-absorption by the sample. The correction and lensing are used together or may be used independently.