Abstract: Systems and methods to estimate 3D TOF scatter include acquisition of 3D TOF data, determination of 2D TOF data from the first TOF data, determination of first estimated scatter based on the second TOF data, reconstruction of a first estimated image based on the first estimated scatter and the second TOF data, determination of attenuated unscattered true coincidences based on the first estimated image, determination of second estimated scatter based on the first TOF data and the attenuated unscattered true coincidences, and reconstruction of an image of the object based on the first TOF data and the second estimated scatter.

Abstract: A translation drive system for an imaging system having an imaging gantry and a gantry base. The system includes at least one upper rail affixed to the imaging gantry and at least one lower rail affixed to the base, wherein the lower rail includes a stop. The system also includes front and lower carriages moveably attached to the lower rail wherein the upper rail is moveably attached to an upper carriage to enable movement of the imaging gantry relative to the base. Further, the system includes an extension spring attached between the lower carriage and the imaging gantry wherein when a lower carriage rear surface contacts the stop, the upper rail moves horizontally past a base rear surface into an extended position wherein the imaging gantry extends horizontally beyond the base rear surface. The system also includes a linear actuator located in the base that moves the imaging gantry.

Abstract: For partial volume correction, the partial volume effect is simulated using patient-specific segmentation. An organ or other object of the patient is segmented using anatomical imaging. For simulation, the locations of the patient-specific object or objects are sub-divided, creating artificial boundaries in the object. A test activity is assigned to each sub-division and forward projected. The difference of the forward projected activity to the test activity provides a location-by-location partial volume correction map. This correction map is used in reconstruction from the measured emissions, resulting in more accurate activity estimation with less partial volume effect.

Abstract: For three-dimensional segmentation from two-dimensional intracardiac echocardiography imaging, the three-dimension segmentation is output by a machine-learnt multi-task generator. Rather than the brute force approach of training the generator from 2D ICE images to output a 2D segmentation, the generator is trained from 3D information, such as a sparse ICE volume assembled from the 2D ICE images. Where sufficient ground truth data is not available, computed tomography or magnetic resonance data may be used as the ground truth for the sample sparse ICE volumes. The generator is trained to output both the 3D segmentation and a complete volume (i.e., more voxels represented than in the sparse ICE volume). The 3D segmentation may be further used to project to 2D as an input with an ICE image to another network trained to output a 2D segmentation for the ICE image. Display of the 3D segmentation and/or 2D segmentation may guide ablation of tissue in the patient.

Abstract: A system and method include training of an artificial neural network to generate an output three-dimensional image volume based on input two-dimensional projection images, the training based on a plurality of subsets of two-dimensional projection images of each of a plurality of sets of two-dimensional projection images and associated ones of three-dimensional image volumes reconstructed from each of the plurality of sets of two-dimensional projection images.

Abstract: A lighting arrangement for a medical imaging system having a cylindrical wall that forms a tunnel that receives a patient to be scanned. The lighting arrangement includes a transparent wall section formed in the wall, wherein the transparent wall section extends along a transparent portion of a wall circumference. The imaging system also includes a lighting device located adjacent an outer surface of the transparent wall section. The lighting device extends along a device portion of a wall circumference corresponding to the transparent portion wherein light emitted by the lighting device is transmitted through the transparent wall section in a direction orthogonal to a longitudinal axis of the tunnel to circumferentially illuminate the tunnel. In addition, a system status is indicated by a color of light emitted by the LEDs. Further, light emitted by the lighting device varies in intensity to indicate a changing count rate.

Abstract: A system and method includes acquisition of a plurality of images, each of the plurality of images representing radiotracer concentration in a respective volume at a respective time period, and training of a neural network, based on the plurality of images, to output data indicative of radiation dose associated with a first volume over a first time period based on a first image representing radiotracer concentration in the first volume over a second time period, the second time period being shorter than the first time period.

Abstract: For ultrasound imaging with an ultrasound scanner, fat fraction of the tissue is measured. The fat fraction may be measured without access to channel data, such as from beamformed data. The speed of sound varies with the fat fraction of tissue, so the fat fraction is used to set the speed of sound in beamforming. Imaging the tissue using the fat fraction-based optimization for speed of sound may provide better images than imaging with an assumed speed.

Abstract: A system and method include an array of sensors electrically coupled to a material capable of converting a gamma ray to electrical charge, where distances between a center of a first sensor and centers of each sensor immediately-adjacent to the first sensor are substantially equal. Signals are collected from each sensor immediately-adjacent to the first sensor, and one of a plurality of logical sub-pixels of the first sensor is determined based on the signals collected from each sensor immediately-adjacent to the first sensor.

Abstract: For quantification of blood flow by an ultrasound system, B-mode images generated with a multi-transmit, coherent image formation produce swirling or other speckle patterns in the blood regions. These patterns, as represented in specially formed B-mode images, are tracked over time to indicate two or three-dimensional velocity vectors of the blood at a B-mode resolution. Various visualizations may be provided at the same resolution, including the velocity flow field, flow direction, vorticity, vortex size, vortex shape, and/or divergence.

Abstract: Disclosed is a novel method of obtaining transmission scan data in a PET scanner by incorporating one or more stationary gamma-ray sources that provide forward scattered gamma-photons that can be used as transmission imaging radiation.

Abstract: Systems and methods include acquisition of magnetic resonance data of a subject disposed in a first position, acquisition of positron emission tomography data of imaging hardware and of the subject disposed substantially in the first position, generation of a subject attenuation correction map of the subject based on the magnetic resonance data, determination of an imaging hardware attenuation correction map associated with the imaging hardware, determination of a target location and orientation of the imaging hardware attenuation correction map with respect to the positron emission tomography data and based on the positron emission tomography data and on the subject attenuation correction map, and application of attenuation correction to the positron emission tomography data based on the imaging hardware attenuation correction map in the target location and orientation and the subject attenuation correction map to generate attenuation-corrected positron emission tomography data.

Abstract: A detector used for tomography imaging is mobile, allowing the detector to move about an object (e.g., patient to be imaged). A swarm of such detectors, such as a swarm of drones with detectors, may be used for tomography imaging. The trajectory or trajectories of the mobile detectors may account for the pose and/or movement of the object being imaged. The trajectory or trajectories may be based, in part, on the sampling for desired tomography. An image of an internal region of the object is reconstructed from detected signals of the mobile detectors using tomography.

Abstract: To optimize an image quality and/or a sensitivity, a Compton camera is adaptable. A scatter detector and/or a catcher detector may move closer to and/or further away from a patient and/or each other. This adaptation allows a balancing of the image quality and the sensitivity by altering the geometry.

Abstract: A method for detecting potential faults in a cooling system that cools a detector electronic assembly (DEA) of a positron emission tomography (PET) imaging system having a plurality of PET detector rings each including a plurality of PET detectors having an associated DEA. The method includes verifying continuity of coolant lines in a coolant flow path of a DEA and calculating a flow rate through a coolant flow path of a DEA. Selected circuit board temperature sensors are used to detect temperature values that serve as surrogates for temperature change of a coolant. Further, the selected temperature sensors are located on hardware that is replicated on different points or locations on the flow path such that the temperature sensors have similar performance characteristics and are of like kind.

Abstract: Systems and methods include an analog-to-logic circuit and a digital processing component. The analog-to-logic circuit receives a first electrical signal, outputs a first logic signal indicating whether or not a voltage of the first pulse is greater than a first threshold voltage, and outputs a second logic signal indicating whether or not the voltage of the first pulse is greater than a second threshold voltage. The digital processing component receives the first logic pulse and the second logic pulse, determines, based on the second logic signal, if the first pulse is valid, and determines, based on the first logic signal, a first trigger time associated with the first pulse.

Abstract: Motion independent acoustic radiation force impulse imaging is provided. Rather than rely on the displacement over time for each location, the displacements over locations for each time are used. Parallel beamforming is used to simultaneously sample across a region of interest. Since it may be assumed that the different locations are subjected to the same motion at the same time, finding a peak displacement over locations for each given time provides peak or profile information independent of the motion. The velocity or other viscoelastic parameter may be estimated from the displacements over locations.

Abstract: Systems and methods for tracking head motion during medical imaging. In accordance to one aspect, a head holder for a medical scanner is provided. The head holder includes at least one movable component that moves with patient's head while the head is placed on the movable component during brain imaging. The head holder further includes one or more inertial measurement units (IMUs) attached to the movable component that measure motion data, wherein any change in orientation of the movable component indicated by the motion data represents movement of the head. The one or more IMUs may communicate with a computer system during brain imaging in substantially real time to record motion parameters.

Abstract: For robotically operating a catheter, translation and/or rotation manipulation is provided along the shaft or away from the handle, such as near a point of access to the patient. A worm drive arrangement may allow for both translation and rotation of the shaft. Some control may be provided by robotic manipulation of the handle, while other control (e.g., fine adjustments) are made by robotic manipulation of the shaft.