Patents Assigned to Sigma-Tau HealthScience S.p.A.
  • Composition comprising a carnitine and glutathione, useful to increase the absorption of glutathione and synergize its effects
    Patent number: 6306392
    Abstract: A composition useful for increasing the absorption of glutathione and for synergizing its effects. This composition may take the form of a dietary supplement, dietetic support or of an actual medicine and comprises: (a) propionyl L-carnitine or a pharmacologically acceptable salt thereof; (b) glutathione or a glutathione-containing yeast; (c) a glutathione-free yeast if the component (b) consists of glutathione. The invention is also directed to methods of making this composition as well as to methods of prevention or treatment using it.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: October 23, 2001
    Assignee: Sigma-Tau Healthscience S.p.A.
    Inventor: Claudio Cavazza
  • Medicament and therapeutical method for treating idiopathic asthenozoospermia
    Publication number: 20010018455
    Abstract: A therapeutical method is disclosed for treating idiopathic asthenozoospermia which comprises orally or parenterally administering to a patient in need thereof a combination preparation comprising in admixture L-carnitine and acetyl L-carnitine or the pharmacologically acceptable salts thereof, in substantially equimolar amouts.
    Type: Application
    Filed: April 5, 2001
    Publication date: August 30, 2001
    Applicant: Sigma-Tau HealthScience, S.p.A.
    Inventor: Claudio Cavazza
  • Water-soluble salts of dodecandioic acid and pharmaceutical and nutritional compositions containing same
    Patent number: 6255503
    Abstract: Water-soluble dodecandioates wherein the cationic moiety is selected from the group comprising the cations of basic aminoacids (e.g. lysine) and choline and orally or parenterally administrable compositions containing same, are disclosed.
    Type: Grant
    Filed: November 30, 1999
    Date of Patent: July 3, 2001
    Assignee: Sigma-Tau Healthscience S.p.A.
    Inventors: Mosé Santaniello, Nazareno Scafetta, Maria Ornella Tinti
  • Nutritional supplement for facilitating skeletal muscle adaptation to strenuous exercise and counteracting defatigation in asthenic individuals
    Patent number: 6245378
    Abstract: A nutritional supplement for facilitating the adaptation of skeletal muscle in individuals udergoing programs of strenuous exercise and counteracting defatigation and weariness in asthenic individuals is disclosed, which comprises a combination of L-camitine, acetyl L-camitine and propionyl L-carnitine as basic active ingredients. Optional ingredients comprise isovaleryl L-carnitine, branched-chained aminoacids and creatine and/or phosphocreatine.
    Type: Grant
    Filed: November 30, 1998
    Date of Patent: June 12, 2001
    Assignee: Sigma-Tau Healthscience S.p.A.
    Inventor: Claudio Cavazza
  • Medicament and therapeutical method for treating idiopathic asthenozoospermia
    Patent number: 6235784
    Abstract: A therapeutical method is disclosed for treating idiopathic asthenozoospermia which comprises orally or parenterally administering to a patient in need thereof a combination preparation comprising in admixture L-carnitine and acetyl L-carnitine or the pharmacologically acceptable salts thereof, in substantially equimolar amouts.
    Type: Grant
    Filed: August 12, 1998
    Date of Patent: May 22, 2001
    Assignee: Sigma-Tau HealthScience S.p.A.
    Inventor: Claudio Cavazza
  • Pharmaceutical composition comprising carnitine or alkanoyl L-carnitine, for the prevention and treatment of diseases brought about by lipid metabolism disorders
    Patent number: 6217898
    Abstract: A pharmaceutical compositions comprising L-carnitine or alkanoyl L-carnitine and hydroxycitric or pantothenic acid or derivatives thereof for the prevention and treatment of diseases brought about by lipid metabolism disorders, is disclosed.
    Type: Grant
    Filed: March 17, 1998
    Date of Patent: April 17, 2001
    Assignee: Sigma-Tau HealthScience S.p.A.
    Inventor: Claudio Cavazza
  • Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans
    Patent number: 6090848
    Abstract: A method is disclosed for treating idiopathic asthenozoospermia and improving sperm quality which comprises orally or parenterally administering to a subject in need thereof a combination preparation comprising either an admixture of or separately packaged L-carnitine and acetyl L-carnitine, or a pharmacologically acceptable salt thereof, in molar ratios ranging from about 4.0:1 to 1:1.5.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: July 18, 2000
    Assignee: Sigma-Tau Healthscience S.p.A.
    Inventor: Claudio Cavazza
  • Medicament and therapeutical method for treating idiopathic asthenozoospermia
    Patent number: 5863940
    Abstract: A therapeutical method is disclosed for treating idiopathic asthenozoospermia which comprises orally or parenterally administering to a patient in need thereof a combination preparation comprising in admixture L-carnitine and acetyl L-carnitine or the pharmacologically acceptable salts thereof, in substantially equimolar amouts.
    Type: Grant
    Filed: December 1, 1997
    Date of Patent: January 26, 1999
    Assignee: Sigma-Tau HealthScience S.p.A.
    Inventor: Claudio Cavazza