Patents Assigned to Sionex Corporation
  • Publication number: 20100282961
    Abstract: A pre-filter assembly including a differential mobility spectrometer (DMS) that is configured to be in-line with a mass spectrometer (MS) such that the MS continuously receives carrier flow from the DMS when the DMS filtering fields are removed.
    Type: Application
    Filed: January 31, 2008
    Publication date: November 11, 2010
    Applicant: SIONEX CORPORATION
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov
  • Patent number: 7812305
    Abstract: The invention relates generally to systems, methods and devices for analyzing samples and, more particularly, to systems using tandem differential mobility spectrometers in combination with a mass analyzer to enhance the analysis process of constituents of a sample.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: October 12, 2010
    Assignees: Sionex Corporation, Northeastern University
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Paul Vouros
  • Patent number: 7714284
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, to sample detection using multiple detection and analytical techniques in combination.
    Type: Grant
    Filed: January 13, 2005
    Date of Patent: May 11, 2010
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Lawrence A. Kaufman, Evgeny Krylov, Gary A. Eiceman
  • Patent number: 7608818
    Abstract: A compact integrated ion mobility based analysis system includes at least one gas chromatograph (GC) column that receives a sample and elutes constituents of the sample where each of the eluted constituents are temporally separated from each other The system also includes at least one ion mobility based sample analyzer that analyzes the eluted constituents based on their ion mobility characteristics. The system further includes a controller that selectively adjusts the temperature within at least one GC column over a period of time and selectively adjusts the temperature within at least one ion mobility based sample analyzer over a period of time.
    Type: Grant
    Filed: May 1, 2006
    Date of Patent: October 27, 2009
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, David B. Wheeler, Kenneth A. Markoski
  • Patent number: 7605367
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, in some embodiments to compact GC-DMS systems, methods, and devices employing enhanced GC column temperature control and configurations to identify various sample constituents.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: October 20, 2009
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, David B. Wheeler, Quan Shi, John A. Wright, Gary A. Eiceman
  • Patent number: 7598489
    Abstract: The invention provides, in various embodiments, systems and methods relating to controlling ion behavior in an ion-based analysis system.
    Type: Grant
    Filed: October 1, 2007
    Date of Patent: October 6, 2009
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Clayton James Morris, Douglas B. Cameron, Erkinjon G. Nazarov, John A. Wright
  • Patent number: 7579589
    Abstract: An ultra compact ion mobility based analyzer in a multilayered chip assembly employing various features such as a ion flow generator to propel ions through an ion mobility based filter and, thereby, reduce analyzer size, cost, and power requirements.
    Type: Grant
    Filed: July 26, 2006
    Date of Patent: August 25, 2009
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Stephen Coy, Stephen D. Kendig, C. James Morris, John A. Wright, Erkinjon G. Nazarov
  • Patent number: 7576319
    Abstract: Disclosed herein are systems, methods and apparatus, for detection and identification of chemical warfare agents (CWAs) using a differential mobility spectrometer.
    Type: Grant
    Filed: February 1, 2008
    Date of Patent: August 18, 2009
    Assignees: Sionex Corporation, The Charles Stark Draper Laboratory, Inc.
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Angela Zapata, Cristina E. Davis, Gary A. Eiceman, Anthony D. Bashall
  • Publication number: 20090189064
    Abstract: An ultra compact ion mobility based analyzer in a multilayered chip assembly employing various features such as a ion flow generator to propel ions through an ion mobility based filter and, thereby, reduce analyzer size, cost, and power requirements.
    Type: Application
    Filed: July 26, 2006
    Publication date: July 30, 2009
    Applicant: SIONEX CORPORATION
    Inventors: Raanan A. Miller, Stephen Coy, Stephen D. Kendig, C. James Morris, John A. Wright, Erkinjon G. Nazarov
  • Publication number: 20090045331
    Abstract: The invention, in various embodiments, is directed to a method for analyzing a sample using a solid-state flow generator that provides a flow of effluent including the sample through an ion mobility based filter.
    Type: Application
    Filed: October 10, 2008
    Publication date: February 19, 2009
    Applicant: SIONEX CORPORATION
    Inventors: Raanan A. Miller, John A. Wright
  • Patent number: 7456394
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, in some embodiments to compact GC-DMS systems and methods, and techniques for correcting nonlinear characteristics in an ion mobility based analyzer.
    Type: Grant
    Filed: February 2, 2005
    Date of Patent: November 25, 2008
    Assignee: Sionex Corporation
    Inventors: Douglas B. Cameron, David B. Wheeler, Quan Shi, Raanan A. Miller, Erkinjon G. Nazarov, John A. Wright
  • Patent number: 7453060
    Abstract: The invention, in various embodiments, is directed to an analyzer using a solid-state flow generator to provide effluent flow along a flow path and deliver a sample to an ion mobility based filter and detector for analysis.
    Type: Grant
    Filed: April 17, 2007
    Date of Patent: November 18, 2008
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, John A. Wright
  • Publication number: 20080224032
    Abstract: A micromechanical field asymmetric ion mobility filter for a detection system includes a pair of spaced substrates defining between them a flow path between a sample inlet and an outlet; an ion filter disposed in the path and including a pair of spaced filter electrodes, one electrode associated with each substrate; and an electrical controller for applying a bias voltage and an asymmetric periodic voltage across the ion filter electrodes for controlling the paths of ions through the filter.
    Type: Application
    Filed: August 20, 2007
    Publication date: September 18, 2008
    Applicant: SIONEX CORPORATION
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov
  • Publication number: 20080185512
    Abstract: A ion mobility-based analyzer system including a first ion mobility-based filter for passing selected ions through a time-varying field where the time-varying field being compensated by an adjustable compensation setting. The analyzer also includes a second ion mobility-based filter for receiving a first portion of ions from the first ion mobility-based filter. The second ion mobility-based filter includes a voltage gradient for separating ions of the first portion of ions where the ions have associated retention times based on their times of flight through the voltage gradient. The second ion mobility-based filter includes a detector for detecting the ions at their retention times. The analyzer system further includes a display that displays the detected ions in a plot relating the retention times of the ions in the second ion mobility-based filter with compensation settings of the first ion mobility-based filter.
    Type: Application
    Filed: April 1, 2008
    Publication date: August 7, 2008
    Applicant: SIONEX CORPORATION
    Inventors: Raanan A. Miller, Evgeny Krylov, Erkinjon G. Nazarov, Gary A. Eiceman, John A. Wright
  • Patent number: 7399959
    Abstract: The invention provides, in various embodiments, systems and methods relating to enhancing the filtering and detection capability of ion mobility based systems by various techniques to counteract a charge buildup in the ion mobility based system.
    Type: Grant
    Filed: December 2, 2005
    Date of Patent: July 15, 2008
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, C. James Morris, Stephen Coy, Edward Bullister
  • Patent number: 7399958
    Abstract: A system for analyzing one or more ion species of a sample including a first ion mobility filter associated with a first flow path for passing first ions of the sample, a second ion mobility filter associated with a second flow path for passing second ions of the sample, a first outlet from the first flow path for passing a portion of the first ions from the first flow path to the second flow path, and a first outlet from the second flow path for removing neutral particles from the second flow path where the first outlet from the second flow path is upstream of the second ion mobility filter in relation to the ion flow in the second flow path.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: July 15, 2008
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Evgeny Krylov, Erkinjon G. Nazarov, Gary A. Eiceman, John A. Wright
  • Publication number: 20080156981
    Abstract: An RF-driven plasma source, including a pair of spaced-apart plasma electrodes, wherein the electrodes act as plates of a capacitor, the gas electrically discharges and creates a plasma of both positive and negative ions, in a clean process that enables efficient sample analysis, with preferred isolated sample photo-ionization, reduced-power operation and also including signal detection with modulated drive electronics.
    Type: Application
    Filed: August 20, 2007
    Publication date: July 3, 2008
    Applicant: SIONEX CORPORATION
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Evgeny Krylov, Gary A. Eiceman, John A. Wright, Stephen D. Kendig, C. James Morris, Douglas B. Cameron
  • Publication number: 20080135745
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, in some embodiments to compact GC-DMS systems, methods, and devices employing enhanced GC column temperature control and configurations to identify various sample constituents.
    Type: Application
    Filed: July 17, 2007
    Publication date: June 12, 2008
    Applicant: SIONEX CORPORATION
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, David B. Wheeler, Quan Shi, John A. Wright, Gary A. Eiceman
  • Publication number: 20080128609
    Abstract: Disclosed herein are systems, methods and apparatus, for detection and identification of chemical warfare agents (CWAs) using a differential mobility spectrometer.
    Type: Application
    Filed: February 1, 2008
    Publication date: June 5, 2008
    Applicants: SIONEX CORPORATION, The Charles Stark Draper Laboratory, Inc.
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Angela Zapata, Cristina E. Davis, Gary A. Eiceman, Anthony D. Bashall
  • Patent number: 7381944
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, to sample detection using enhanced condition control and data interpretation.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: June 3, 2008
    Assignee: Sionex Corporation
    Inventors: Douglas B. Cameron, David B. Wheeler, Quan Shi, Raanan A. Miller, Erkinjon G. Nazarov, Evgeny Krylov, Stephen Coy, Gary A. Eiceman