Patents Assigned to Sionex Corporation
  • Patent number: 7812305
    Abstract: The invention relates generally to systems, methods and devices for analyzing samples and, more particularly, to systems using tandem differential mobility spectrometers in combination with a mass analyzer to enhance the analysis process of constituents of a sample.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: October 12, 2010
    Assignees: Sionex Corporation, Northeastern University
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Paul Vouros
  • Patent number: 7714284
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, to sample detection using multiple detection and analytical techniques in combination.
    Type: Grant
    Filed: January 13, 2005
    Date of Patent: May 11, 2010
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Lawrence A. Kaufman, Evgeny Krylov, Gary A. Eiceman
  • Patent number: 7608818
    Abstract: A compact integrated ion mobility based analysis system includes at least one gas chromatograph (GC) column that receives a sample and elutes constituents of the sample where each of the eluted constituents are temporally separated from each other The system also includes at least one ion mobility based sample analyzer that analyzes the eluted constituents based on their ion mobility characteristics. The system further includes a controller that selectively adjusts the temperature within at least one GC column over a period of time and selectively adjusts the temperature within at least one ion mobility based sample analyzer over a period of time.
    Type: Grant
    Filed: May 1, 2006
    Date of Patent: October 27, 2009
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, David B. Wheeler, Kenneth A. Markoski
  • Patent number: 7605367
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, in some embodiments to compact GC-DMS systems, methods, and devices employing enhanced GC column temperature control and configurations to identify various sample constituents.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: October 20, 2009
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, David B. Wheeler, Quan Shi, John A. Wright, Gary A. Eiceman
  • Patent number: 7598489
    Abstract: The invention provides, in various embodiments, systems and methods relating to controlling ion behavior in an ion-based analysis system.
    Type: Grant
    Filed: October 1, 2007
    Date of Patent: October 6, 2009
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Clayton James Morris, Douglas B. Cameron, Erkinjon G. Nazarov, John A. Wright
  • Patent number: 7579589
    Abstract: An ultra compact ion mobility based analyzer in a multilayered chip assembly employing various features such as a ion flow generator to propel ions through an ion mobility based filter and, thereby, reduce analyzer size, cost, and power requirements.
    Type: Grant
    Filed: July 26, 2006
    Date of Patent: August 25, 2009
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Stephen Coy, Stephen D. Kendig, C. James Morris, John A. Wright, Erkinjon G. Nazarov
  • Patent number: 7576319
    Abstract: Disclosed herein are systems, methods and apparatus, for detection and identification of chemical warfare agents (CWAs) using a differential mobility spectrometer.
    Type: Grant
    Filed: February 1, 2008
    Date of Patent: August 18, 2009
    Assignees: Sionex Corporation, The Charles Stark Draper Laboratory, Inc.
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Angela Zapata, Cristina E. Davis, Gary A. Eiceman, Anthony D. Bashall
  • Patent number: 7456394
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, in some embodiments to compact GC-DMS systems and methods, and techniques for correcting nonlinear characteristics in an ion mobility based analyzer.
    Type: Grant
    Filed: February 2, 2005
    Date of Patent: November 25, 2008
    Assignee: Sionex Corporation
    Inventors: Douglas B. Cameron, David B. Wheeler, Quan Shi, Raanan A. Miller, Erkinjon G. Nazarov, John A. Wright
  • Patent number: 7453060
    Abstract: The invention, in various embodiments, is directed to an analyzer using a solid-state flow generator to provide effluent flow along a flow path and deliver a sample to an ion mobility based filter and detector for analysis.
    Type: Grant
    Filed: April 17, 2007
    Date of Patent: November 18, 2008
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, John A. Wright
  • Patent number: 7399958
    Abstract: A system for analyzing one or more ion species of a sample including a first ion mobility filter associated with a first flow path for passing first ions of the sample, a second ion mobility filter associated with a second flow path for passing second ions of the sample, a first outlet from the first flow path for passing a portion of the first ions from the first flow path to the second flow path, and a first outlet from the second flow path for removing neutral particles from the second flow path where the first outlet from the second flow path is upstream of the second ion mobility filter in relation to the ion flow in the second flow path.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: July 15, 2008
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Evgeny Krylov, Erkinjon G. Nazarov, Gary A. Eiceman, John A. Wright
  • Patent number: 7399959
    Abstract: The invention provides, in various embodiments, systems and methods relating to enhancing the filtering and detection capability of ion mobility based systems by various techniques to counteract a charge buildup in the ion mobility based system.
    Type: Grant
    Filed: December 2, 2005
    Date of Patent: July 15, 2008
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, C. James Morris, Stephen Coy, Edward Bullister
  • Patent number: 7381944
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, to sample detection using enhanced condition control and data interpretation.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: June 3, 2008
    Assignee: Sionex Corporation
    Inventors: Douglas B. Cameron, David B. Wheeler, Quan Shi, Raanan A. Miller, Erkinjon G. Nazarov, Evgeny Krylov, Stephen Coy, Gary A. Eiceman
  • Publication number: 20080121794
    Abstract: The invention provides, in various embodiments, systems and methods relating to controlling ion behavior in an ion-based analysis system.
    Type: Application
    Filed: October 1, 2007
    Publication date: May 29, 2008
    Applicant: Sionex Corporation
    Inventors: Raanan A. Miller, Clayton James Morris, Douglas B. Cameron, Erkinjon G. Nazarov, John A. Wright
  • Patent number: 7355170
    Abstract: Disclosed herein are systems, methods and apparatus, for detection and identification of analytes in a volatilized or volatilizable sample, using the mobility-based signature that is produced when the volatilized sample is passed through an ion mobility based analyzer.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: April 8, 2008
    Assignees: Sionex Corporation, The Charles Stark Draper Laboratory, Inc.
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Angela Zapata, Cristina E. Davis, Gary A. Eiceman, Anthony D. Bashall
  • Patent number: 7339164
    Abstract: The invention provides, in various embodiments, systems and methods relating to controlling ion behavior in an ion-based analysis system.
    Type: Grant
    Filed: August 23, 2006
    Date of Patent: March 4, 2008
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, C. James Morris, Douglas B. Cameron, Erkinjon G. Nazarov, John A. Wright
  • Patent number: 7279680
    Abstract: An RF-driven plasma source, including a pair of spaced-apart plasma electrodes, wherein the electrodes act as plates of a capacitor, the gas electrically discharges and creates a plasma of both positive and negative ions, in a clean process that enables efficient sample analysis, with preferred isolated sample photo-ionization, reduced-power operation and also including signal detection with modulated drive electronics.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: October 9, 2007
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Evgeny Krylov, Gary A. Eiceman, John A. Wright, Stephen D. Kendig, C. James Morris, Douglas B. Cameron
  • Patent number: 7274015
    Abstract: In a system for chemical analysis, an RF-driven plasma ionization device including a pair of spaced-apart and plasma-isolated electrodes, the electrodes are connected to a power source wherein the electrodes act as plates of a capacitor of a resonant circuit, the gas electrically discharges and creates a plasma of both positive and negative ions, and the voltage is applied as a continuous alternating waveform or as a series of pulses, such as a packet waveform.
    Type: Grant
    Filed: August 7, 2002
    Date of Patent: September 25, 2007
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Evgeny Krylov, Gary A. Eiceman, Lawrence A. Kaufman
  • Patent number: 7262407
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, in some embodiments to compact GC-DMS systems, methods, and devices employing enhanced GC column temperature control and configurations to identify various sample constituents.
    Type: Grant
    Filed: June 20, 2006
    Date of Patent: August 28, 2007
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, David B. Wheeler, Quan Shi, John A. Wright, Gary A. Eiceman
  • Patent number: 7230238
    Abstract: System for control of ion species behavior in a time-varying filter field of an ion mobility-based spectrometer to improve species identification, based on control of electrical and environmental aspects of sample analysis.
    Type: Grant
    Filed: December 13, 2004
    Date of Patent: June 12, 2007
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Evgeny Krylov, Gary A. Eiceman
  • Patent number: 7227134
    Abstract: The invention relates generally to ion mobility-based systems, methods and devices for analyzing samples.
    Type: Grant
    Filed: November 24, 2004
    Date of Patent: June 5, 2007
    Assignee: Sionex Corporation
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Lawrence A. Kaufman, Douglas B. Cameron