Abstract: The present invention relates to a method of prepairing a heat-resistant polyamide by carrying out condensation polymerization with a monomer mixture including a diester compound and a diamine compound. The present invention provides an economical method of prepairing a heat-resistant polyamide in that a monomer, a raw material, is simply and chiefly prepared, and the polymerizing reaction time is short because it does not need solvent separately.
Abstract: Disclosed is a composition for transdermal administration containing tolterodine. The composition comprises lidocaine or a pharmaceutically acceptable salt thereof to achieve enhanced skin penetration. The composition enhances the skin penetration of tolterodine. Therefore, a successful commercial application of a tolterodine-containing transdermal preparation based on the composition can be expected.
Type:
Grant
Filed:
February 17, 2011
Date of Patent:
August 19, 2014
Assignee:
SK Chemicals Co., Ltd.
Inventors:
Yong Youn Hwang, Won-Jae Choi, Jae-Sun Kim, Yeo-Jin Park, Joon-Gyo Oh, Bong-Yong Lee, Hae-In Rhee, Jong-Seob Im
Abstract: The present invention provides a compound of formula (I) or a prodrug thereof useful for treating or preventing irritable bowel syndrome, and a composition comprising the compound as an active ingredient. Also, the present invention provides a method for treating or preventing irritable bowel syndrome, which comprises administrating a therapeutically or prophylactically effective amount of the compound or the composition to a subject in need of treating or preventing irritable bowel syndrome.
Type:
Application
Filed:
May 16, 2012
Publication date:
July 31, 2014
Applicant:
SK CHEMICALS CO., LTD.
Inventors:
Won suk Sun, Hyo Jin Jeon, Dongsun Min, Woongsik Kim, Taeksu Kim, Do-Seung Kum, Keun-Ho Ryu, Hae-In Rhee, Yang Hae Park, Hyun-Joo Son, Eun-ju Park, Bong-yong Lee, Hojin Namgung, Minseok Park, Minseok Kang
Abstract: The present invention relates to a stable pharmaceutical composition for injection containing docetaxel and a method of preparing the same. More particularly, the present invention relates to a pharmaceutical composition for injection containing docetaxel having better storage stability than conventional medications, which is prepared by dissolving docetaxel, a water-insoluble compound, in distilled water after mixing it with cyclodextrin (CD) and a water-soluble polymer such as hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method of preparing the same.
Type:
Grant
Filed:
May 22, 2007
Date of Patent:
July 29, 2014
Assignee:
SK Chemicals Co., Ltd.
Inventors:
Nam Ho Kim, Jin Young Lee, Jae-Sun Kim, Nam Kyu Lee, Woo Jae Jang, Joon Gyo Oh, Yoon-Jung Lee, Woong Sik Kim, Jin-Heung Sung, Key An Um
Abstract: The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.
Type:
Grant
Filed:
December 21, 2009
Date of Patent:
July 29, 2014
Assignee:
SK Chemicals Co., Ltd.
Inventors:
Wonrack Choi, Chang-Kyun Han, Tae Kon Kim, Guang-Jin Im, Chil Mann Jung, Se Jun Yun, Bongcheol Kim, Soomin Lee, Wie-Jong Kwak
Abstract: The present invention relates to a pharmaceutical or cosmetic composition and a method for promoting eyelash growth, wherein nipradilol or pharmaceutically or cosmetically acceptable salts thereof are used as active ingredients. The composition of the invention may comprise prostaglandin F2? analogues.
Type:
Application
Filed:
June 8, 2012
Publication date:
July 10, 2014
Applicant:
SK CHEMICALS CO., LTD.
Inventors:
Sang-hwan Kang, Keun-Ho Ryu, DongChul Shin, Bong-yong Lee
Abstract: The present invention relates to a polyarylene sulfide that is prepared from a composition including 100 parts by weight of solid sulfur, 500 to 10,000 parts by weight of iodinated aryl compounds, and 0.03 to 30 parts by weight of a sulfur-containing polymerization terminator with respect to 100 parts by weight of the solid sulfur, and has a melting temperature (Tm) of 255 to 285° C., and luminosity of 40 or higher as defined by the CIE Lab color model, and a process of preparing the same. The PAS resin is prepared from a composition including a sulfur-containing polymerization terminator and thus has excellent thermal properties and luminosity.
Type:
Application
Filed:
February 13, 2014
Publication date:
July 10, 2014
Applicant:
SK CHEMICALS CO., LTD.
Inventors:
Young-Rok Lee, Il-Hoon Cha, Yong-Jun Shin, Jun-Sang Cho
Abstract: Disclosed is a composition effective in reducing skin wrinkles. The composition comprises a phosphodiesterase 5 (PDE5) inhibitor, preferably the compound of chemical formula 1, more preferably, mirodenafil as an active ingredient. Further disclosed is a method for reducing skin wrinkles using the composition.
Abstract: Disclosed is a composition effective in reducing skin wrinkles. The composition comprises or uses a phosphodiesterase 5 (PDE5) inhibitor as an active ingredient. Further disclosed is a method for reducing skin wrinkles using the composition.
Abstract: A method for preparing polyarylene sulfide having reduced iodine content and excellent thermal stability is described. The method includes reacting a composition comprising diiodide aromatic compounds, sulfur compounds, and a polymerization terminator. The preparation method may effectively reduce iodine content of polyarylene sulfide to prevent corrosion of post processing equipment, improve properties of polyarylene sulfide such as thermal stability, and the like, and thus, it may be usefully applied in the industrial field relating to preparation of polyarylene sulfide.
Type:
Grant
Filed:
January 31, 2011
Date of Patent:
June 24, 2014
Assignee:
SK Chemicals Co., Ltd.
Inventors:
Yong-Jun Shin, Il-Hoon Cha, Jae-Bong Lim, Sung-Gi Kim
Abstract: Disclosed is a composition effective in reducing skin wrinkles. The composition comprises or uses a phosphodiesterase 5 (PDE5) inhibitor as an active ingredient. Further disclosed is a method for reducing skin wrinkles using the composition.
Abstract: The present invention relates to a method for preparing microspheres and microspheres prepared thereby, more particularly to a method for preparing a polymeric microsphere, including preparing an emulsion including a polymer compound, a drug, a water-insoluble organic solvent and a dispersion solvent and adding to the prepared emulsion a base or an acid to remove the water-insoluble organic solvent from the emulsion, a polymeric microsphere prepared thereby, and a composition for drug delivery including the microsphere. According to the present invention, a drug-containing polymer microsphere may be prepared quickly and simply without the solvent evaporation or solvent extraction process, thereby reducing water consumption and minimizing wastewater generation.
Type:
Grant
Filed:
May 12, 2011
Date of Patent:
April 15, 2014
Assignees:
Ewha University-Industry Collaboration Foundation, SK Chemicals Co., Ltd.
Abstract: A novel copper phthalocyanine compound with low absorptivity in the visible light region and high absorptivity in the near-infrared light region, and a near-infrared absorption filter using the same are disclosed. The near-infrared absorption copper phthalocyanine compound is represented by the following Formula 1, wherein, A2, A3, A6, A7, A10, A11, A14 and A15 are independently OR1, SR2 or a halogen atom, wherein at least four thereof are OR1; A1, A4, A5, A8, A9, A12, A13 and A16 are independently OR1, SR2, NR3R4 or a halogen atom, wherein at least two thereof are NR3R4, and at least four thereof are OR1; R1, R2, R3 and R4 are independently an alkyl group of 1 to 10 carbon atoms, an aryl group of 6 to 10 carbon atoms, or an aralkyl group of 7 to 15 carbon atoms.
Type:
Grant
Filed:
November 5, 2009
Date of Patent:
April 8, 2014
Assignee:
SK Chemicals Co., Ltd.
Inventors:
Ju-Sik Kang, Jeong-Ho Park, Yu-Mi Chang
Abstract: Disclosed is a method for preparing an iodinated aromatic compound. More specifically, disclosed is a method of preparing an iodinated aromatic compound by iodinating an aromatic compound in the presence of oxygen over a zeolite catalyst, in which the aromatic compound and a monoiodo analog of the aromatic compound, or a monoiodo aromatic compound, as raw materials, are allowed to react with iodine. In comparison with a method in which only the aromatic compound is used as a raw material without adding the monoiodo compound, the disclosed method can increase the productivity of diiodo compounds and the selectivity to a p-diiodo compound and, at the same time, suppress side reactions, thus lengthening the life span of the catalyst.
Type:
Grant
Filed:
November 14, 2011
Date of Patent:
March 18, 2014
Assignee:
SK Chemicals Co., Ltd.
Inventors:
Han Seok Kim, Jong In Lee, Il Hoon Cha, Yoon Seo Lee
Abstract: A method for preparing polymer microparticles with a reduced initial burst, and the polymer microparticles prepared thereby, the method including: contacting polymer microparticles with an alcohol aqueous solution, the polymer microparticles prepared thereby, and use for drug delivery of the polymer microparticles.
Type:
Application
Filed:
November 20, 2013
Publication date:
March 13, 2014
Applicant:
SK CHEMICALS CO., LTD.
Inventors:
Hong Kee KIM, Kyu Ho Lee, Joon-Gyo OH, Bong-Yong Lee
Abstract: A vanadium phthalocyanine compound with low absorptivity in the visible light region and high absorptivity in the near-infrared light region, and represented by the following Formula:
Type:
Grant
Filed:
November 5, 2009
Date of Patent:
March 11, 2014
Assignee:
SK Chemicals Co., Ltd.
Inventors:
Yu-Mi Chang, Ju-Sik Kang, Jeong-Ho Park
Abstract: The present invention relates to a herbal drug composition for cartilage protection comprising plant extracts of Clematis Radix, Trichosanthis Radix, and Prunellae Spica and an optimal content of rosmarinic acid to: (i) alleviate pains; (ii) inhibit the acute/chronic inflammation, platelet/whole blood aggregation, immunocyte (B-lymphcyte and T-lymphcyte) proliferation, inflammation-inducing enzyme activities, and enzyme activities associated with degradation of joint tissue; (iii) scavenge activity of toxic active oxygen radicals; and (iv) further provide excellent cartilage protection activity to be effectively used as an anti-inflammatory agent with analgesic effects, blood circulation enhancer, arthritis therapeutic agent and cartilage protective.
Type:
Grant
Filed:
February 21, 2012
Date of Patent:
February 18, 2014
Assignee:
SK Chemicals Co., Ltd.
Inventors:
Chang-Kyun Han, Wie-Jong Kwak, Ki Won Joung, Hun Seung Yoo, Do Seung Kum, Yong-Baik Cho, Keun Ho Ryu, Hae In Rhee, Taek Su Kim, In Ho Jung, So Yoon Lee, Jung Bum Yi, Joo Hyon Kim, Key An Um
Abstract: The present invention relates to a polylactic acid resin film which has excellent flexibility, mechanical properties, stability, and transparency while having a specific biodegradability of the polylactic acid resin, and is useful as a packaging material. The present invention provides a polylactic acid resin film, comprising a polylactic acid resin including a hard segment comprising a specific polylactic acid repeating unit, and a soft segment comprising a polyurethane polyol repeating unit in which a specific polyether polyol repeating units are linearly linked via a urethane bond, wherein the total Young's modulus in both machine direction and transverse direction of the film is 350 to 750 kgf/mm2, and the total initial tensile strength in both machine direction and transverse direction of the film is 20 kgf/mm2 or more.
Type:
Application
Filed:
November 2, 2011
Publication date:
February 6, 2014
Applicant:
SK CHEMICALS CO., LTD.
Inventors:
Young-Man Yoo, Jae-Il Chung, Tae-Woong Lee, Kye-Yune Lee
Abstract: The present invention relates to a copolymer polyester resin and a molded product using the same, and more specifically to a copolymer polyester resin that contains 10˜80 mol % of 1,4-cyclohexane dimethanol, 0.1˜50 mol % of a diol compound expressed as HO—(CH2)n—CO—(CH2)b—OH (where a and b are integers in the range 1˜5), and ethylene glycol or other diols so that the sum of its entire diol composition is 100 mol % based on dicarboxylic acid. The copolymer polyester resin of the present invention enables reduction of cycle time, improvement of product processability and prevention of PET bottle deformation during mold processing with a heat-shrinking label by complementing low temperature shrinkage, maintaining a high shrinkage rate, and reducing shrinkage stress.