Patents Assigned to SmithKline Beecham Biologicals (s.a.)
  • BASB019 proteins and genes from Moraxella catarrhalis, antigens, antibodies, and uses
    Patent number: 6764834
    Abstract: The invention provides BASB019 polypeptides and polynucleotides encoding BASB019 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Grant
    Filed: January 3, 2001
    Date of Patent: July 20, 2004
    Assignee: SmithKline Beecham Biologicals, s.a.
    Inventor: Jean-Louis Ruelle
  • BASB006 polypeptides from neisseria meningitidis and immunogenic compositions thereof
    Publication number: 20040137530
    Abstract: The invention provides BASB006 polypeptides and polynucleotides encoding BASB006 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 15, 2004
    Applicant: Smithkline Beecham Biologicals S.A.
    Inventor: Joelle Thonnard
  • BASB013 DNA and proteins from neisseria meningitidis
    Publication number: 20040132983
    Abstract: The invention provides BASB013 polypeptides and polynucleotides encoding BASB013 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Application
    Filed: December 18, 2003
    Publication date: July 8, 2004
    Applicant: SmithKline Beecham Biologicals S.A.
    Inventor: Jean-Louis Ruelle
  • Vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminum phosphate
    Patent number: 6756040
    Abstract: The invention relates to a vaccine formulation for the prevention of Haemophilus Influenzae Type B (Hib) infections and where the antigen is adsorbed onto aluminum phosphate. The invention also relates to a multivalent vaccines, that is a vaccine for the amelioration or treatment of more than one disease states. The present invention also relates to the production and use of such vaccines in medicine.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: June 29, 2004
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventors: Julien Peetermans, Pierre Hauser
  • BASB013 DNA and proteins from Neisseria meningitidis
    Patent number: 6709657
    Abstract: The invention provides BASB013 polypeptides and polynucleotides encoding BASB013 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Grant
    Filed: December 4, 2000
    Date of Patent: March 23, 2004
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventor: Jean-Louis Ruelle
  • Compounds
    Patent number: 6706270
    Abstract: The invention provides BASB041, 43, 44 and 48 polypeptides and polynucleotides encoding BASB041, 43, 44 and 48 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Grant
    Filed: September 6, 2001
    Date of Patent: March 16, 2004
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventors: Jean-Louis Ruelle, Vincent Georges Christian Louis Verlant
  • Cloning of BASB023 antigen from Moraxella catarrhalis
    Patent number: 6706271
    Abstract: The invention provides BASB023 polypeptides encoding BASB023 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: March 16, 2004
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventor: Joelle Thonnard
  • BASB028 polypeptides and polynucleotides encoding therefor from moraxella catarrhalis
    Patent number: 6706494
    Abstract: The invention provides BASB028 polypeptides and polynucleotides encoding BASB028 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: March 16, 2004
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventor: Jean-Louis Ruelle
  • Moraxella catarrhalis PILQ proteins
    Patent number: 6706269
    Abstract: The invention provides BASB031 polypeptides and polynucleotides encoding BASB031 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: March 16, 2004
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventors: Jean-Louis Ruelle, Carlota Vinals Y De Bassols
  • Vaccines
    Publication number: 20040043038
    Abstract: The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccines compositions are potent inducers of a range of immune responses.
    Type: Application
    Filed: September 3, 2003
    Publication date: March 4, 2004
    Applicant: SmithKline Beecham Biologicals S.A.
    Inventors: Patricia Marie Momin, Nathalie Marie-Josephe Garcon
  • BASB006 polypeptides from Neisseria meningitidis and immunogenic compositions thereof
    Patent number: 6696062
    Abstract: Provided are BASB006 polypeptides from Neisseria meningitidis. Also provided are fusion proteins containing BASB006 polypeptides. The invention also relates to immunogenic compositions containing BASB006 polypeptides.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: February 24, 2004
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventor: Joelle Thonnard
  • Methods of treating human females susceptible to HSV infection
    Patent number: 6692752
    Abstract: A method of administering a vaccine to females to prevent or treat infections associated with pathogens which cause sexually transmitted diseases is described. The vaccine comprises one or more antigens for the prevention or treatment of sexually transmitted diseases, for example an HSV glycoprotein D or an immunological fragment thereof, and an adjuvant, especially a TH-1 inducing adjuvant. The use of the vaccine components for the formulation of a vaccine composition for the prevention or treatment of sexually transmitted diseases in female subjects is also described.
    Type: Grant
    Filed: September 14, 2000
    Date of Patent: February 17, 2004
    Assignee: SmithKline Beecham Biologicals S.A.
    Inventors: Moncef Mohamed Slaoui, Pierre G. Vandepapeliere
  • Teat nozzle for dosing device with connection means
    Patent number: 6684918
    Abstract: A teat nozzle suitable for pediatric oral dosing of a fluid medicament comprising a tubular conduit which is engageable with a socket, and has at least one engagement part which can engage with an internal thread in the socket. The teat nozzle facilitates connection between the conduit and the socket. Dosing devices such as syringes and squeezable capsules provided with the nozzle, and a connection means for a vial having such a socket, are also described.
    Type: Grant
    Filed: December 13, 2001
    Date of Patent: February 3, 2004
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventors: Jacques Thilly, Christian Vandecasserie
  • Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines
    Patent number: 6676942
    Abstract: The invention related to novel Borrelia, and OspA antigens derived therefrom. These antigens show little homology with know OspA's and are therefore useful as vaccine and diagnostic reagents. Multicomponent vaccines based on OspA's from different Borrelia groups are also disclosed.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: January 13, 2004
    Assignees: SmithKline Beecham Biologicals (s.a.), Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V., Deutsches Krebs Forschungszentrum Stiftung des Offentlichen Rechts
    Inventors: Yves Lobet, Markus Simon, Ulrich Schaible, Reinhard Wallich, Michael Kramer
  • Vaccine against Mumps containing a Jeryl-Lynn virus strain
    Patent number: 6656476
    Abstract: A new mumps vaccine is presented, comprising a homogeneous pure isolate derived from the Jeryl-Lynn strain of mumps virus.
    Type: Grant
    Filed: August 7, 2002
    Date of Patent: December 2, 2003
    Assignee: SmithKline Beecham Biologicals (S.A.)
    Inventors: Nigel Maurice Harford, Brigitte Desiree Alberte Colau, Jean Didelez
  • Moraxella catarrahalis polynucleotides and polypeptides
    Patent number: 6649171
    Abstract: The invention provides BASB021 polypeptides and polynucleotides encoding BASB021 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: November 18, 2003
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventor: Joelle Thonnard
  • Hepatitis vaccines containing 3-O-deacylated monophoshoryl lipid A
    Publication number: 20030211120
    Abstract: A vaccine formulation for the treatment or prophylaxis of hepatitis, especially hepatitis B, infections is provided comprising the hepatitis antigen and a suitable carrier such as alum in combination with 3-O-deacylated monophosphoryl lipid A. Combination vaccines including the vaccine formulation are also described.
    Type: Application
    Filed: June 19, 2003
    Publication date: November 13, 2003
    Applicant: SmithKline Beecham Biologicals S.A.
    Inventors: Nathalie Marie-Joseph Claude Garcon-Johnson, Pierre Hauser, Clothilde Thiriart, Pierre Voet
  • CASB414:antigen overexpressed in several tumors
    Patent number: 6635255
    Abstract: CASB414 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB414 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly colon cancers, autoimmune diseases, and related conditions.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: October 21, 2003
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventors: Claudine Elvire Marie Bruck, Jean-Pol Cassart, Thierry Coche, Carlota Vinals Y De Bassols
  • Compounds from moraxella catarrhalis
    Patent number: 6627728
    Abstract: The invention provides BASB010 polypeptides and polynucleotides encoding BASB010 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: September 30, 2003
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventor: Joelle Thonnard
  • Polynucleotides and polypeptides BASB033 from neisseria meningitidis and their uses
    Patent number: 6627204
    Abstract: The invention provides BASB033 polypeptides and polynucleotides encoding BASB033 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: September 30, 2003
    Assignee: SmithKline Beecham Biologicals s.a.
    Inventor: Jean-Louis Ruelle