Abstract: A passively transformable wheel includes a wheel base including a centrally positioned transmitter rotation shaft and one or more passive leg rotation shafts positioned in the outer periphery; a force transmitter rotatably coupled to an end of the transmitter rotation shaft, the force transmitter including a trigger slide and one or more passive leg joints spaced apart from one another; a trigger leg arranged between the wheel base and the force transmitter and rotatably coupled to the trigger leg rotation shaft, the trigger leg including a trigger joint fitted to the trigger slide; and one or more passive legs arranged between the wheel base and the force transmitter so as not to interfere with the trigger leg and rotatably coupled to the passive leg rotation shafts, the passive legs including one or more passive leg slides engaging with the passive leg joints of the force transmitter.

Abstract: A power supply and a gate driver includes a power switching element to control current, a control circuit to output a control signal for opening or closing of the power switching element, and a gate drive circuit to open or close the power switching element in accordance with the control signal. The gate drive circuit includes a first inductive circuit connected to a supply voltage source, and a second inductive circuit connected to an input stage of the power switching element, and transfers electrical energy stored in the input stage of the power switching element, using the first and second inductive circuits. Accordingly, electrical energy supplied to the input stage of the power switching element during an ON state of the power switching element is again recovered during an OFF state of the power switching element.

Abstract: The present invention relates to a compound inhibiting Hsp90 and a pharmaceutical composition comprising the same as an active ingredient. The compounds represented by formula 1 and formula 2 of the present invention suppress the expression of Hsp90 so that they can inhibit the accumulation of HIF-1?, the Hsp90 client protein, and also efficiently inhibit the activation of VEGF. In addition, these compounds display low cytotoxicity, so that they can be effectively used as an active ingredient of an anti-cancer agent, a diabetic retinopathy treating agent, and an anti-arthritic agent.

Abstract: Disclosed herein are apparatus and method for transferring, focusing and purging powder for direct printing at low temperature. A filter is provided between an operation chamber housing in which a work target is disposed and a reservoir tank which contains powder to adjust the amount of particles transferred from the reservoir tank into the operation chamber housing. A pressure unit connected to the reservoir tank generates air pressure for applying powder to the work target. A purging unit connected to the reservoir tank generates pressure for returning powder that has remained in the operation chamber housing, the filter, etc. to the reservoir tank after work has been completed. The apparatus is configured such that a series of process of transferring powder to be applied to the surface of the work target and returning remnant powder to the reservoir tank can be rapidly and smoothly conducted.

Abstract: The present invention relates to a CDK-inhibiting pyrrolopyrimidine carboxamide derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating liver cell cancer. Compositions comprising a pyrrolopyrimidine carboxamide derivative of the present invention suppress the cell growth of SNU-354 cell, which is a liver cancer stem cell in humans, by inhibiting CDK1 and CDK2, and induces cell apoptosis of the cell by inhibiting CDK7 and CDK 7. Such compositions are useful for preventing or treating liver cell cancer.

Abstract: Disclosed is a method of producing 2,3-butanediol using a recombinant yeast having a 2,3-butanediol biosynthesis pathway controlled in a metabolic engineering manner. The method enables production of 2,3-butanediol at high production efficiency from glucose or xylose using a recombinant yeast wherein enzymatic activity of pyruvate decarboxylase is inhibited and exotic genes associated with 2,3-butanediol biosynthesis are introduced.

Abstract: The present invention relates a peptide having cancer selective translocation function, and the use thereof, and more particularly to a VEGF-binding protein transduction domain (VPTD) represented as SEQ ID NO: 1 or a heparin-binding protein transduction domain (HPTD) represented as SEQ ID NO: 2, which bind specifically to VEGF and heparin, which are overexpressed specifically in tumor cells or tumor tissues, and to a conjugate comprising a drug linked to the peptide. The peptide and the peptide-drug conjugate bind specifically to VEGF and heparin in tumor cells or tumor tissue and accumulate in the tumor cells or tumor tissue, and thus can be used for the accurate diagnosis and treatment of cancer. Also, the non-specific distribution of the peptide or the conjugate in the body after administration is inhibited, and thus the side effects thereof can be minimized. Accordingly, the peptide or the conjugate is useful for the diagnosis and treatment of cancer.

Abstract: Disclosed herein are an apparatus and method of performing inter-cell interference coordination in a heterogeneous network. The apparatus includes a reception unit, a determination unit, a generation unit, and a transmission unit. The reception unit receives a modulation and coding scheme (MCS) level from a small cell base station in each frame. The determination unit determines a calculated MCS level based on the MCS level and an interfering signal estimated through probabilistic modeling. The generation unit generates a ratio of subframes, in which data will not be transmitted, to all subframes of a frame based on the MCS level and the calculated MCS level. The transmission unit transmits the ratio and the calculated MCS level to the small cell base station.

Abstract: TRPV1 inhibitory peptide and a composition thereof for skin-aging prevention, wrinkle improvement, skin-whitening, or alleviating inflammation, irritation or pain is described, where the TRPV1 inhibitory peptide inhibits the expressions of MMP and proinflammatory cytokines induced by UV exposure and reduces skinfold thickness and intracellular Ca2+influx.

Abstract: Disclosed herein are apparatus and method for transferring, focusing and purging powder for direct printing at low temperature. A filter is provided between an operation chamber housing in which a work target is disposed and a reservoir tank which contains powder to adjust the amount of particles transferred from the reservoir tank into the operation chamber housing. A pressure unit connected to the reservoir tank generates air pressure for applying powder to the work target. A purging unit connected to the reservoir tank generates pressure for returning powder that has remained in the operation chamber housing, the filter, etc. to the reservoir tank after work has been completed. The apparatus is configured such that a series of process of transferring powder to be applied to the surface of the work target and returning remnant powder to the reservoir tank can be rapidly and smoothly conducted.

Abstract: A composition for diagnosing, treating, and preventing liver disease, more particularly a composition for diagnosing liver disease comprising a material for measuring the grade of TM4SF5 (transmembrane 4 L six family member 5 or four-transmembrane L6 superfamily member 5) protein, a kit for diagnosing liver disease comprising the composition, a method for providing information necessary for diagnosing liver disease composed of the following steps: measuring the level of TM4SF5 protein and the expressions and phosphorylations of TM4SF5 expression related signaling proteins; and comparing the measured levels with those of the normal control, a method for screening a material for treating liver disease, and a composition for treating or preventing liver disease comprising a material inhibiting TM4SF5 protein expression or the expressions and phosphorylations of TM4SF5 expression related signaling proteins.

Abstract: Provided are a nonvolatile memory device and a deduplication method thereof. The nonvolatile memory device includes a plurality of data storages written in a unit of data block; and a storage controller dividing write-requested data in a unit of data block to generate a plurality of data blocks, determining whether each of predetermined data blocks from among the plurality of data blocks is duplicated, generating parity data with reference to non-duplicated data blocks from among the predetermined data blocks, and controlling the plurality of data storages such that the parity data and the non-duplicated data blocks are written into at least one of the plurality of data storages. Since a deduplication operation is performed before generating parity data to assure reliability of data, the number of write operations is reduced and restoration probability of the nonvolatile memory device increases.

Abstract: The present invention provides a quantizer with a sigma-delta modulator, an analog-to-digital converter including the same and a quantization method using the same capable of obtaining a high signal-to-noise ratio with a relatively small number of comparators. The quantizer, the analog-to-digital converter and the quantization method of the present invention reduces quantization errors and increases noise shaping order.

Abstract: A polymer composition, a cross-linked polymer formed therefrom, an electrolyte membrane and electrode for a fuel cell including the same, and a fuel cell employing the electrode and the electrolyte membrane. The cross-linked polymer includes an oxazine-based monomer capable of retaining phosphoric acid and has excellent mechanical strength. When the cross-linked polymer is used, an electrode and electrolyte membrane for a fuel cell with enhanced capability of retaining phosphoric acid at a wide range of temperature may be manufactured, leading to long-term durability, and enhanced proton conductivity.

Abstract: Provided is a nanoprobe based on a self-replicating biological material. The nanoprobe includes a binding agent existing in a first region of the biological material and capable of binding specifically to a target analyte, and nanoparticles existing in a second region of the biological material and providing an optical detection signal. The use of the nanoprobe enables quantitative analysis and multiplexed analysis of a target. In addition, the nanoprobe is easy to fabricate on a large scale.

Abstract: Techniques for preparing polymer nanocomposites (PNCs) are provided. In one embodiment, a polymer extruding device includes a barrel configured to accommodate a raw material, a shaft disposed in the barrel, a motor coupled to the shaft and configured to rotate the shaft to move the raw material, and a die coupled to the barrel and including one or more first injector configured to inject nanoparticles into the die, thereby forming a layer of the nanoparticles on a surface of the raw material. The polymer extruder may further include a rotor disposed at one end of the die and configured to receive the raw material from the die.

Abstract: Provided is a data processing apparatus that may include a storage unit, a first calculator, and a second calculator. The storage unit may store a plurality of training data obtained by motion sensing. The first calculator may calculate a first transformation matrix by performing a regression analysis for the plurality of training data. The second calculator may calculate first output data by applying the first transformation matrix to first input data.

Abstract: Disclosed is a method for preparing a transferable membrane having a nanometer scale dimension in thickness and pore size by non-solvent vapor-induced phase separation process, comprising spin-casting a polymer solution in a closed humid chamber and controlling the relative humidity (RH) of the chamber using at least one supersaturated salts solution whereby the density of the pores are controlled. Also provided is a TNT membrane prepared by the present method and its use. The present membrane can be advantageously used as co-culture platform facilitating versatile and controllable cell co-culture assays and further allowing the quantitative analysis of paracrine communications between cells for example between cancer cells and different types of stromal cells by providing an in vivo-like environment, which can offer more in-vivo-like results to identify key signaling molecules for therapeutic targets of a disease.

Abstract: A double wound rotor type motor with a constant alternating current or direct current power supply input and a control method thereof is disclosed. The wound rotor type motor includes: a stator in which a coil directly connected to a single phase grid power supply or a direct current power supply is wound; a rotor that is rotatably supported in the stator; a power conversion device that is attached to the rotor and controls a rotor current without connection of a separate external power supply; and a control circuit that is connected to the power conversion device and controls the power conversion device.

Abstract: This invention relates to whitlockite and a method for manufacturing the same. The method includes adding, to water, a calcium ion supplying material and a cation supplying material containing a cation (X) other than the calcium ion to prepare a cation aqueous solution, adding a phosphoric acid supplying material to the cation aqueous solution, and aging the cation aqueous solution including the phosphoric acid supplying material. As a result, whitlockite having high purity and high crystallinity can be mass produced using a simple process.