Patents Assigned to SNU R&DB Foundation
  • Patent number: 10251824
    Abstract: The present disclosure relates to a method for inducing pluripotent stem cells by inducing reprogramming and/or dedifferentiation of differentiated adult cells using shikimic acid, a plant extract or plant stem cells containing shikimic acid and an extract of dedifferentiated stem cells (callus), pluripotent stem cells prepared by the method and a composition containing the pluripotent stem cells. In accordance with the present disclosure, ethical concerns implicated with the use of eggs to prepare pluripotent stem cells such as embryonic stem cell can be resolved. And, because the plant stem cell extract unharmful to human is used, pluripotent stem cells with proven safety can be prepared and they may be used to develop immunocompatible cell therapy agents suited for individuals. In addition, by pluripotent stem cells from individuals having diseases, the present disclosure will be very useful in studying the cause of diseases and devolving therapeutic strategy.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: April 9, 2019
    Assignees: AMOREPACIFIC CORPORATION, SNU R&DB FOUNDATION
    Inventors: Ah Reum Kim, Su Na Kim, Won Seok Park, Yoo Wook Kwon, Young Bae Park, Hyo Soo Kim, Jae Seung Paek
  • Patent number: 10250165
    Abstract: Disclosed is a high speed actuator. The high speed actuator includes an actuation part configured to cause deformation such as bending or twisting and an active stiffness controller on a surface of the actuation part or in the actuation part configured to control in real time a stiffness (e.g., of the actuator) according to an external signal. The active stiffness controller may control a stiffness of the high speed actuator in order for the actuator to be actuated at a high speed. Moreover, since the stiffness of the actuator is controlled in real time, a speed of the actuator may be controlled in real time.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: April 2, 2019
    Assignee: SNU R&DB Foundation
    Inventors: Sung Hoon Ahn, Sung Hyuk Song
  • Patent number: 10224376
    Abstract: Provided is an organic photoelectronic device including a first light-transmitting electrode positioned at a light incidence side, a second light-transmitting electrode facing the first light-transmitting electrode, a photoactive layer positioned between the first light-transmitting electrode and the second light-transmitting electrode and selectively absorbing light in a given (or, alternatively, desired or predetermined) wavelength region, and a selective light transmittance layer positioned between the first light-transmitting electrode and the photoactive layer, between the second light-transmitting electrode and the photoactive layer, or between the first light-transmitting electrode and the photoactive layer and between the second light-transmitting electrode and the photoactive layer and increasing transmittance of the light in a wavelength region other than the given (or, alternatively, desired or predetermined) wavelength region absorbed by the photoactive layer, and an electronic device including th
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: March 5, 2019
    Assignees: Samsung Electronics Co., Ltd., SNU R&DB Foundation
    Inventors: Kyu Sik Kim, Jang-Joo Kim, Gae Hwang Lee, Ryuichi Satoh, Yong Wan Jin, Dae-Ho Kim
  • Patent number: 10220367
    Abstract: Provided is a method of forming a microsphere having a structural color, which includes providing a composition for generating a structural color including a curable material and magnetic nanoparticles dispersed in the curable material, forming an emulsion by adding the composition for generating a structural color to an immiscible solvent, arranging the magnetic nanoparticles located in the emulsion droplet of the curable material in a one-dimensional chain structure by applying a magnetic field to the emulsion, and fixing the chain structure by curing the emulsion droplet.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: March 5, 2019
    Assignee: SNU R&DB FOUNDATION
    Inventors: Sunghoon Kwon, Hyoki Kim, Yadong Yin, Jianping Ge
  • Publication number: 20190067347
    Abstract: An omnidirectional image sensor and a method of manufacturing the omnidirectional image sensor are provided. An image sensor may include a plurality of photodiodes, and a spherical structure comprising a plurality of protrusions, wherein the plurality of photodiodes are disposed between the plurality of protrusions, and wherein the spherical structure comprises a plurality of spherical wedges.
    Type: Application
    Filed: March 16, 2018
    Publication date: February 28, 2019
    Applicants: SAMSUNG ELECTRONICS CO., LTD., SNU R&DB FOUNDATION
    Inventors: DONG KYUNG NAM, Dae Hyeong KIM, YANG HO CHO, Mincheol LEE, Jun Kyul SONG
  • Patent number: 10217997
    Abstract: Disclosed herein are a positive electrode active material including at least one selected from among compounds represented by Formula 1 below and a lithium secondary battery including the same that is capable of improving lifetime characteristics and rate characteristics while exhibiting excellent safety: Li[LixMyM?(1-x-y)]O2-zAz (1), where M is at least one element selected from a group consisting of Ru, Mo, Nb, Te, Re, Ir, Pt, Cr, S, W, Os, and Po, M? is at least one element selected from a group consisting of Ni, Ti, Co, Al, Mn, Fe, Mg, B, Cr, Zr, Zn, and second row transition metals, A is a negative monovalent or divalent anion, and 0<x<0.3, 0.2?y?0.5, 0?z<0.5, and 0.2<x+y<0.8.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: February 26, 2019
    Assignees: LG Chem, Ltd., Research Affairs of SNU & SNU R&DB Foundation
    Inventors: Hoe Jin Hah, Kyoung Ho Kim, Il Hong Kim, Je Young Kim, Kisuk Kang, Jihyun Hong
  • Patent number: 10215757
    Abstract: The present invention relates to a fluorescence sensor capable of real-time imaging for measuring a cellular thiol level. The present invention reveals that the fluorescence intensity of the fluorescent real-time SH group-tracer (FreSH-Tracer) of the present invention increases or decreases continuously, ratiometrically or reversibly depending on the thiol level in living cells, and thus can be usefully used as a biosensor which is remarkably susceptible to quantitative or qualitative real-time detection of the cellular thiol level in living cells.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: February 26, 2019
    Assignees: CELL2IN, INC., SNU R&DB FOUNDATION, KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: In-Gyu Kim, Ki Hang Choi, Eui Man Jeong, Heun Soo Kang
  • Publication number: 20180369467
    Abstract: The present invention relates to a blood pump. The blood pump according to the present invention includes: a housing including an inlet, through which blood flows, at an upper part of the housing and an outlet, through which the blood is discharged, along an edge of the housing; an impeller part, which is rotatable and disposed inside the housing, including a plurality of blades on the surface thereof so as to move the blood flowing in through the inlet toward the outlet by using a centrifugal force; a rotary shaft member disposed to penetrate the center part of the impeller part so as to support the impeller part to be rotatable which moves the blood to the lower part thereof; and a magnetic body disposed on the impeller part for rotating the impeller part in a predetermined direction according to a change in a magnetic field outside the housing.
    Type: Application
    Filed: March 20, 2017
    Publication date: December 27, 2018
    Applicant: SNU R&DB FOUNDATION
    Inventors: Jung Chan LEE, Hee Chan KIM
  • Patent number: 10159756
    Abstract: The present invention relates to a complex prepared by conjugating indocyanine green to mannosyl serum albumin in order to overcome shortcomings such as low light stability and low in vivo stability of indocyanine green that is a fluorescent dye reagent that is used during surgical operations, a preparation method thereof, an optical imaging probe comprising the same, and a kit comprising the probe.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: December 25, 2018
    Assignees: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SNU R&DB FOUNDATION
    Inventors: Hyun Koo Kim, Jae Min Jeong, Yun-Sang Lee
  • Patent number: 10130725
    Abstract: A method for labeling exosomes with a radioactive substance using an amine group on surfaces of the exosomes includes providing a cell-derived exosome, treating a surface of the exosome with N-hydroxysuccinimide-azadibenzocyclooctyne (NHS-ADIBO), and mixing the treated exosome with N3-introduced chelator-radioactive substance to conduct a reaction between the chelator and an amine group present on the surface of the exosome, wherein the radioactive substance is introduced inside the exosome by the above reaction. The exosomes can be stably labeled at high labeling efficiency, and the exosomes can be favorably used as an agent for nuclear medicine imaging and therapeutic imaging for confirming the biological distribution of exosomes and whether the exosomes move to target organs and target diseases in animals including a human being.
    Type: Grant
    Filed: May 13, 2015
    Date of Patent: November 20, 2018
    Assignees: SNU R&DB FOUNDATION, POSTECH ACADEMY—INDUSTRY FOUNDATION
    Inventors: Dong Soo Lee, Do Won Hwang, Hongyoon Choi, Yun-Sang Lee, Jae Min Jeong, Yong Song Gho, Su Chul Jang
  • Patent number: 10134487
    Abstract: A memory device may include a memory cell array, a bloom-filter circuit, a cache memory circuit, and a selecting circuit. The bloom-filter circuit may be configured to output a determination result signal that indicates that there is a possibility that a received address is one of failed addresses corresponding to failed cells of the memory cell array. The cache memory circuit may be configured to, store the failed addresses and a first set of data corresponding to the respective failed addresses, and configured to, when the determination result signal indicates a possibility, provide a comparison result signal by determining whether received address coincides with one of the failed addresses. The selecting circuit may be configured to output either first data of the first set of data or second data of the memory cell array corresponding to the received address based on determination result signal and comparison result signal.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: November 20, 2018
    Assignees: SAMSUNG ELECTRONICS CO., LTD., SNU R&DB FOUNDATION
    Inventors: Sang-Hyuk Kwon, Young-Hoon Son, Jung-Ho Ahn
  • Patent number: 10128502
    Abstract: Disclosed herein are a positive electrode active material including at least one selected from among compounds represented by Formula 1 below and a lithium secondary battery including the same that is capable of improving lifetime characteristics and rate characteristics while exhibiting excellent safety: xLi2MyMn(1-y)O3-zAz*(1?x)LiM?O2-z?A?z? (1), where M is at least one element selected from a group consisting of Ru, Mo, Nb, Te, Re, Ir, Pt, Cr, S, W, Os, and Po, M? is at least one element selected from a group consisting of Ni, Ti, Co, Al, Mn, Fe, Mg, B, Cr, Zr, Zn, and second row transition metals, A and A? are each independently a negative monovalent or divalent anion, and 0<x<1, 0.3<y<1, 0?z<0.5, and 0?z?<0.5.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: November 13, 2018
    Assignees: LG Chem, Ltd., Research Affairs of SNU & SNU R&DB Foundation
    Inventors: Hoe Jin Hah, Sun Sik Shin, Kyoung Ho Kim, Il Hong Kim, Je Young Kim, Kisuk Kang, Jihyun Hong
  • Patent number: 10117805
    Abstract: An acupressure device includes an acupressure section, a driving part and a control part. The acupressure section is disposed in front of the belly and presses the belly. The driving part is connected to the acupressure section and fixed at a backside of a user and moving the acupressure section toward the belly. The control part is controlled by the user and changing an intensity of a pressure from the acupressure section.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: November 6, 2018
    Assignee: SNU R&DB FOUNDATION
    Inventors: Kyu Jin Cho, Sang Yoep Lee, Merewether Gene Brown
  • Patent number: 10100011
    Abstract: The present invention relates to a novel pentadienoyl piperidine derivative, a pharmaceutical composition containing the same for prevention or treatment of metabolic diseases, and a functional food composition using the same for improvement or relief of metabolic diseases. The pentadienoyl piperidine derivative of the present invention inhibits the differentiation of preadipocytes, reduces body weight, visceral fat, blood lipid levels, and blood glucose levels, improves a blood liver function index, and suppresses metabolic inflammation responses. Thus, ultimately, the derivative can be usefully used as a medicine or a functional food composition, which exhibits the preventive or therapeutic activity for metabolic diseases selected from the group consisting of obesity, diabetes, dyslipidemia, fatty liver and insulin resistance syndrome.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: October 16, 2018
    Assignees: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, SNU R&DB FOUNDATION
    Inventors: Tae Sun Park, Lak Shin Jeong
  • Patent number: 10103162
    Abstract: Provided is a vertical neuromorphic devices stacked structure comprising a main gate which is formed on a substrate and has a vertical pillar shape, a main gate insulating layer stack formed on outer side surface of the main gate; a semiconductor region formed on outer side surface of the main gate insulating layer stack, a plurality of electrode layers formed on the side surface of the semiconductor region, a plurality of control gates formed on the side surface of the semiconductor region; and a plurality of control gate insulating layer stacks which are surrounding surfaces of the control gates and are formed between the control gate and the semiconductor region, and between the control gate and the electrode layer, and wherein the electrode layers and the control gates surrounded by the control gate insulating layer stack are stacked sequentially and alternately on the side surface of the semiconductor region.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: October 16, 2018
    Assignee: SNU R&DB FOUNDATION
    Inventors: Jong-Ho Lee, Chul-Heung Kim, Suhwan Lim
  • Patent number: 10097618
    Abstract: A cluster system and a communication method in the cluster system are disclosed herein. The cluster system includes one or more nodes. Each of the one or more nodes includes at least one physical computation device and a virtualization module. The virtualization module manages at least one computation device. The each of the one or more nodes operates as a host node based on the virtual computation device.
    Type: Grant
    Filed: January 13, 2015
    Date of Patent: October 9, 2018
    Assignee: SNU R&DB FOUNDATION
    Inventors: Jaejin Lee, Jungwon Kim, Junghyun Kim
  • Patent number: 10079335
    Abstract: Disclosed is a smart soft composite actuator which enables user-desiring deformation by changing the position of smart material functioning as an active component, wherein the smart soft composite actuator comprises a smart material whose shape is changeable based on an external signal; and a matrix for supporting the smart material and determining an external shape, wherein the smart material is positioned inside the matrix or in a surface of the matrix, and at least one of in-plane shear deformation and out-of-plane deformation is realized by controlling the position of smart material.
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: September 18, 2018
    Assignee: SNU R&DB Foundation
    Inventors: Sung Hoon Ahn, Hyung Jung Kim, Gil Yong Lee, Kyung Tae Lee, Renzhe Wu, Ji Soo Kim, Sung Hyuk Song
  • Patent number: 10077399
    Abstract: The present invention provides a water-soluble fluorescent compound of resveratrone 6-O-?-glucoside [(E)-4-(8-hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)naphthalen-2-yl)but-3-en-2-one] and its derivatives of Formula I which have at least one water-soluble substituent, and a method for preparing the same by a photochemical reaction of resveratrol 3-O-?-glucoside and its derivatives of having Formula 3 which are not fluorescent. Said new water-soluble fluorescent compounds has single-photon absorptive characteristics and/or two-photon absorptive characteristics as well as no or little toxicity, and can be usefully utilized in fields that requires water-soluble fluorescent characteristics (diagnosis, fluorescent probe, in vivo imaging, display, etc.).
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: September 18, 2018
    Assignee: SNU R&DB FOUNDATION
    Inventors: Seong Keun Kim, Il Seung Yang, Seon Jin Hwang, Jung Eun Lee, Jong Woo Lee, Jun Hee Kang, Eun Hak Lim
  • Patent number: 10074855
    Abstract: An electrode for a lithium secondary battery including a silicon-based alloy having an expansion coefficient of 10% or greater and an electrochemically inactive whisker, and a lithium secondary battery using the electrode for a lithium secondary battery.
    Type: Grant
    Filed: May 27, 2014
    Date of Patent: September 11, 2018
    Assignees: Samsung SDI Co., Ltd., SNU R&DB Foundation
    Inventors: Jae-Hyuk Kim, Young-Ugk Kim, Seung-Uk Kwon, Soon-Sung Suh, Hee-Young Chu, Duk-Hyoung Yoon, Chang-Ui Jeong, Yo-Han Park, Kyu-Hwan Oh, Seoung-Bum Son, Seul-Cham Kim, Chan-Soon Kang
  • Patent number: 10058335
    Abstract: The present invention relates to a modularized patient-specific registration guide and a system using the same and, more specifically, to a modularized patient-specific registration guide capable of rapidly carrying out an initial registration step for a bone, which is a surgical site, and inducing a registration step to be easily performed even during an operation, and a system using the same. The modularized patient-specific registration guide, according to one embodiment of the present invention, is a registration guide manufactured according to a three-dimensional shape of a bone obtained in an imaging device, the registration guide comprising: a first member having one or more markers and one or more extending parts that come in contact with the bone, and having a groove on one side thereof; and a second member accommodated in or separable from the groove of the first member and having one or more markers.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: August 28, 2018
    Assignee: SNU R&DB FOUNDATION
    Inventors: Kun Woo Lee, Tae Ho Jang