Patents Assigned to Sofradim Production
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Patent number: 12016971Abstract: Systems and methods for tissue engineered synthetic support structures, such as grafts and patches are provided. The systems and methods can be used to make tissue engineered planar sheathes or meshes that can be fashioned into substantially planar or non-planar 3D tissue/organ structures adaptable to structure and organs within a human or mammalian body. The systems and methods can use bioink deposited on a material having specified properties and matured under specified conditions to create the tissue engineered planar sheathes or meshes having biomechanical and biological properties tailored to a particular tissue.Type: GrantFiled: November 18, 2021Date of Patent: June 25, 2024Assignees: Medtronic, Inc., Sofradim ProductionInventors: Markus W. Reiterer, Kimberly A Chaffin, Darlene P. Nebinger, Angela M Throm Quinlan, Michael F. Wolf, Yves Bayon
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Publication number: 20220354992Abstract: Systems and methods for tissue engineered synthetic support structures, such as grafts and patches are provided. The systems and methods can be used to make tissue engineered planar sheathes or meshes that can be fashioned into substantially planar or non-planar 3D tissue/organ structures adaptable to structure and organs within a human or mammalian body. The systems and methods can use bioink deposited on a material having specified properties and matured under specified conditions to create the tissue engineered planar sheathes or meshes having biomechanical and biological properties tailored to a particular tissue.Type: ApplicationFiled: November 18, 2021Publication date: November 10, 2022Applicants: Medtronic Inc., Sofradim ProductionInventors: Markus W. Reiterer, Kimberly A. Chaffin, Darlene P. Nebinger, Angela M. Throm Quinlan, Michael F. Wolf, Yves Bayon
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Patent number: 11426106Abstract: A medical drain sensor is provided located in a region of a drain tube which has turbulent or re-circulatory exudate flow. Means are provided in some embodiments to promote or enhance such flow.Type: GrantFiled: May 1, 2018Date of Patent: August 30, 2022Assignees: Sofradim Production, CEA (Commissariat A L'energie Atomique Et Aux Energies Alternatives)Inventors: Yves Bayon, Dagmar Guyader, Maxime Gougis, Mélanie Alias, Séverine Vignoud, Frederic Bottausci, Pascal Mailley
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Patent number: 11058332Abstract: In-vivo systems and methods for the detection of early signs of post-surgery infection are described. The in-vivo systems include a drain system with a tube configured to drain fluids from a surgery site, at least one sensor unit for sensing the presence of at least one infection biomarker, a processor for processing a signal generated by the at least one sensor unit, a transmitter for transmitting the signal, and a notification system for receiving the signal, analyzing the signal by comparing it to a threshold, determining presence of infection, and generating an indication on the presence of infection.Type: GrantFiled: September 25, 2015Date of Patent: July 13, 2021Assignee: Sofradim ProductionInventor: Yves Bayon
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Patent number: 10807265Abstract: The present invention relates to a porous support intended to be removably positioned on a top side of a perforated plate of a table of a vacuum hold down device, the perforated plate having a bottom side connected to a vacuum system for producing reduced pressure on the bottom side, wherein the porous support comprises a perforated tray provided on one side with outer reliefs and on the other side with a blade penetrable porous structure fixed thereon. The invention further relates to a vacuum hold down device comprising such a support. The invention also relates to a process for replacing a first porous support by a second porous support in such a device.Type: GrantFiled: February 12, 2015Date of Patent: October 20, 2020Assignee: Sofradim ProductionInventors: Stephane Rochet, Thomas Vial
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Patent number: 10743976Abstract: The present invention relates to a synthetic prosthesis for tissue reinforcement comprising: a porous knit made from a monofilament of a synthetic biocompatible material, said knit defining two opposite faces, a first face and a second face, a synthetic non porous biodegradable film comprising at least a copolymer of at least ?-caprolactone, said film covering at least part of said first face, a synthetic biodegradable binder bonding said film to said first face, said binder comprising at least a polymer of ?-caprolactone, wherein said second face of said porous knit is left open to cell colonization. The invention also relates to a method for forming such a prosthesis.Type: GrantFiled: June 1, 2016Date of Patent: August 18, 2020Assignees: Sofradim Production, Covidien LPInventors: Julie Lecuivre, Nicolas Prost, Nicholas Maiorino, Matthew Prescott, Thomas Corso
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Patent number: 10687929Abstract: The present invention relates to a surgical instrument (1) for deploying a prosthesis (200) and includes a first layer and second layer assembled together so as to define an internal space accessible to said surgical instrument (1) by means of an opening provided in said first layer, said surgical instrument including at least one sheet (2) made of a flexible resilient material, said sheet continuously overlapping itself one or more times so as to define a plurality of levels forming a spiral (3). The invention also relates to a kit including such a surgical instrument and such a prosthesis.Type: GrantFiled: July 16, 2014Date of Patent: June 23, 2020Assignee: Sofradim ProductionInventors: Pierre Bailly, Geneviève Doucet
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Patent number: 10682215Abstract: The invention relates to a method for forming a mesh having a barbed suture attached thereto, comprising the following steps: a) producing a knitted structure on a knitting machine comprising at least one needle-bed with three guide bars, on a length corresponding to N stitches ranging from 1 to N, wherein i) a first knit portion is produced along stitches ranging from 1 to x, where 1<x<N, ii) a second knit portion is produced for stitches ranging from (x+1) to N, in which the knitting pattern produces at least one weft stitched chain stitch, b) cutting the second knit portion on both sides of the weft stitched chain stitch and along an edge separating the second knit portion from the first knit portion, while maintaining the weft stitched chain stitch attached to the first knit portion. The invention also relates to the mesh obtained by this method.Type: GrantFiled: September 27, 2017Date of Patent: June 16, 2020Assignee: Sofradim ProductionInventors: Xavier Couderc, Pierre Bailly
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Patent number: 10675137Abstract: The present invention relates to a prosthesis for repairing a inguinal hernia defect. The prosthesis includes a piece of biocompatible material having a preformed three-dimensional shape including: a first portion forming a partial spherical cap surface, shaped and dimensioned so as to substantially conform to the shape of the anterior abdominal wall; a second portion extending from an inferior edge of the first portion and forming a wavy-shaped wall, shaped and dimensioned so as to substantially conform to the shape of the psoas muscle; and a third portion forming an arched part extending longitudinally in the inferior direction from a medial inferior corner of the first portion, the arched part extending radially substantially in the front direction, the third portion being intended to face the medial inferior area of the inguinal anatomy.Type: GrantFiled: April 27, 2018Date of Patent: June 9, 2020Assignee: Sofradim ProductionInventors: Pierre Bailly, Mylene Desorme, Suzelei Montanari
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Patent number: 10660741Abstract: The invention relates to a prosthesis for supporting a breast implant comprising: a reinforcement part configured to receive a curved lower portion of a breast implant, the reinforcement part having an elongation under 50N in the vertical direction of E1, a fixation part intended to be fixed to the pectoral muscle, the fixation part having an elongation under 50N in the vertical direction of E2, and a transition part connecting together the reinforcement part and the fixation part, said transition part having an elongation under 50N in the vertical direction of E3, wherein E3 is greater than E1 and greater than E2.Type: GrantFiled: March 14, 2018Date of Patent: May 26, 2020Assignee: Sofradim ProductionInventors: Genevieve Doucet, Thierry Brune, Xavier Couderc, Cecile Beausseron-Valentin
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Patent number: 10653508Abstract: The invention relates to a prosthesis (1) for the repair of an inguinal hernia comprising: a textile (2) of elongate shape, a resilient frame (3) connected to said textile, characterized in that said frame comprises a convex cranial segment (3c), a caudal segment (3d), a lateral corner segment (3b) joining together the convex cranial segment and the caudal segment, and a folding segment (5) joining a medial end of said convex cranial segment to a point located on the caudal segment while leaving the region of the medial end of the textile free of any frame, said frame being able to adopt an unstressed configuration, in which said textile is deployed, and a stressed configuration, in which said convex cranial segment, said caudal segment and said folding segment are substantially collected together and aligned on one folding direction, said textile forming thereby at least one fold along said folding direction.Type: GrantFiled: December 12, 2017Date of Patent: May 19, 2020Assignee: Sofradim ProductionInventors: Pierre Bailly, Mylene Desorme, Genevieve Doucet
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Patent number: 10646321Abstract: The present invention relates to a prosthesis (1) for hernia repair comprising a reinforcement layer (2), a first barrier layer (3) of anti-adhesion material covering at least a part of a surface of the reinforcement layer, and a second barrier layer of anti-adhesion material covering a remaining part of the surface of the reinforcement layer, the second barrier layer being formed of one or more flap member(s) (4).Type: GrantFiled: December 20, 2016Date of Patent: May 12, 2020Assignee: Sofradim ProductionInventors: Sebastien Francois, Michel Therin, Nicolas Prost
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Patent number: 10632207Abstract: The present disclosure relates to compounds and medical devices activated with a solvophobic material functionalized with a first reactive member and methods of making such compounds and devices.Type: GrantFiled: November 13, 2015Date of Patent: April 28, 2020Assignee: Sofradim ProductionInventors: Sébastien Ladet, Philippe Gravagna
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Patent number: 10624989Abstract: The present invention relates to an implant (10) comprising: a substrate (1) the surface of which comprising oxidized cellulose, said oxidized cellulose having a degree of oxidation ranging from 0.5 to 1, and a multilayer coating covering said substrate, said multilayer coating comprising at least a first layer (2) adjacent said substrate, said first layer being formed of chitosan, and a second layer (3) adjacent said first layer, said second layer being formed of oxidized cellulose having a degree of oxidation ranging from 0.5 to 1. The invention further relates to a method for preparing such an implant.Type: GrantFiled: May 29, 2019Date of Patent: April 21, 2020Assignee: Sofradim ProductionInventors: Aurelie Serrero, Robert Vestberg, Suzelei Montanari
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Patent number: 10577731Abstract: The present invention relates to an openwork prosthetic knit (1) made from a single piece based on at least a first yarn made of biocompatible polymer material that defines a first face (2) and a second face that are opposite one another and from a second biocompatible yarn that generates barbs (5) that protrude outwards from at least said first face, characterized in that said first face comprises at least one longitudinal strip (4) in the direction of the manufacture of said knit, over which it is provided with said barbs (5), and at least one longitudinal strip (3) in the direction of the manufacture of said knit, over which it is free of such barbs. It also relates to a process for manufacturing such a knit (1) and to a prosthesis comprising such a knit (1).Type: GrantFiled: March 21, 2017Date of Patent: March 3, 2020Assignee: Sofradim ProductionInventor: Julie Lecuivre
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Patent number: 10548704Abstract: The present invention relates to a prosthetic fabric comprising an arrangement of yarns defining at least two faces for said fabric, said fabric comprising, on at least one of its faces, one or more barbs that protrude outwards relative to said face, characterized in that said barbs are covered with a coating made of a water-soluble biocompatible material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.Type: GrantFiled: August 15, 2017Date of Patent: February 4, 2020Assignee: Sofradim ProductionInventors: Suzelei Montanari, Pearl Rey
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Patent number: 10549015Abstract: The present invention relates to a method for preparing a surgical anti-adhesion barrier film comprising the following steps: a°) a first solution, comprising an oxidized collagen is prepared, b) a polyphosphate compound is added to the solution of a) in a quantity so as to obtain a concentration of polyphosphate ranging from 0.007 to 0.7 %, by weight, with respect to the total weight of the solution, c) the pH of the solution obtained in b) is adjusted to about 9 by addition of a base or to about 5.1 by addition of an acid, d) a diluted solution is prepared by adding water to solution of c), e) a first layer of solution obtained in c) is casted on an inert support, f) before complete gelation of the layer obtained in d), a second layer, of diluted solution obtained in d) is applied on top of said first layer and let to gelify, g) the gelified first and second layers are dried to obtain a film.Type: GrantFiled: September 23, 2015Date of Patent: February 4, 2020Assignee: Sofradim ProductionInventors: Nicolas Prost, Delphine Petit, Xavier Bourges
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Patent number: 10472750Abstract: The present invention relates to a prosthesis (100) comprising an openworked three-dimensional knit (101) comprising a front face and a rear face, each face being formed with one or more laps of yarns defining pores on said face, the front face being bound to the rear face by connecting yarns defining a spacer, characterized in that the connecting yarns are distributed so that they define an entanglement of yarns crossing each other at the spacer, without obstructing the pores of the front and rear faces.Type: GrantFiled: January 30, 2017Date of Patent: November 12, 2019Assignee: Sofradim ProductionInventor: Julie Lecuivre
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Patent number: 10441678Abstract: Mono- and multi-layered implants include at least one porous layer made from a freeze dried aqueous solution containing chitosan, the solution having a pH of less than about 5.Type: GrantFiled: April 26, 2018Date of Patent: October 15, 2019Assignee: Sofradim ProductionInventors: Sébastien Ladet, Julien Claret
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Patent number: 10433944Abstract: The package (1) for a surgical mesh (100) comprises: a receiving member (2) configured and dimensioned to receive at least one surgical mesh (100), and a covering member (3) configured and dimensioned to cover the said at least one surgical mesh (100) maintaining with the receiving member (2) the surgical mesh (100) in a substantially flat position, and a gas channelling network interposed between the said receiving member (2) and the said covering member (3) configured to channel a sterilization gas within the at least one surgical mesh (100).Type: GrantFiled: April 18, 2016Date of Patent: October 8, 2019Assignee: Sofradim ProductionInventors: Rebecca Ferrand, Thomas Vial, Barbara Grepinet