Abstract: A bioresorbable and biocompatible compound for surgical use is composed of functionalized collagen cross-linked with a glycosaminoglycan.

Abstract: Isoelastic porous meshes useful in hernia repair have pores that remain open under physiological loads.

Abstract: The present invention relates to a prosthetic fabric (5) comprising an arrangement (2) of yarns that define at least first and second opposite faces (2a, 2b) for said fabric, said fabric comprising on at least said first face, one or more barbs (3) that protrude outwards relative to said first face, said fabric being covered, at least partly, on said second face with a microporous layer made of a bioresorbable material, said barbs being covered with a coating made of a water-soluble material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.

Abstract: The invention concerns a device comprising: a packaging box for the flexible material part, dimensioned to hold said part flat; folding means for folding said part without direct handling; and a reception tube for receiving said folded flexible material part. The invention is characterized in that the folding means comprise; a traction suture connected to the flexible material part, which passes through the tube, and, walls forming a funnel whereof the base emerges proximate to the opening of the tube through which the flexible material part is designed to be inserted into said tube, said funnel being designed, when a traction is exerted on the traction suture, to gradually fold down the zones of the part located laterally relative to the tube towards the zone of the part located opposite the opening of said tube, to enable the part to be inserted into the tube.

Abstract: The present invention relates to a prosthetic fabric comprising an arrangement of yarns defining at least two faces for said fabric, said fabric comprising, on at least one of its faces, one or more barbs that protrude outwards relative to said face, characterized in that said barbs are covered with a coating made of a water-soluble biocompatible material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.

Abstract: Cell cultures or tissue engineering supports, include at least a porous matrix based on a collagen sponge which defines first pores and a porous three-dimensional knit which defines second pores, the porous matrix filling the three-dimensional knit and all the first and second pores being at least partially interconnected with one another.

Abstract: The present invention relates to a prosthetic open knit fabric (10) made as a single piece, based on an arrangement consisting of several sets of yarns of a biocompatible polymer material, comprising, continuously in the direction of production of the knit, a central strip (11) and two lateral strips (12), one on each side of the central strip, characterized in that it comprises one or more set(s) of pillar stitch yarns defining a pillar stitch pattern, the said one or more set(s) of pillar stitch yarns extending across the entire width of the central strip (11) and of the lateral strips (12) and together forming a first threading across the width of the central strip and a second threading across the width of the lateral strips, the said first and second threading being different, and at least two partial weft stitching sets. The present invention also relates to a method of producing such a knit fabric and to an implant for supporting prolapses obtained from such a knit fabric.

Abstract: The present invention relates to a composite prosthesis for reinforcement of a tissue structure, including a porous textile support which includes an arrangement of threads each composed of at least one filament of nonabsorbable polymer material, said textile support defining a microporous texture including the interstices located between at least two threads at the sites of contact of one thread with at least one other thread, wherein, in at least one protected zone of the textile support, a hydrophilic absorbable material coats the textile support, forming a film enveloping and penetrating into the arrangement of threads, occluding at least the microporous texture, but without forming a plane layer covering at least one face of the textile support. It also relates to a process for preparing such a composite reinforcement prosthesis.

Abstract: The present disclosure relates to implantable bioabsorbable medical devices having an amphiphilic coating for delaying the degradation of the device and methods of making such devices.

Abstract: Cross-linked fibers include first and second precursors, each possessing a core and at least one functional group known to have click reactivity when exposed to UV radiation. Mixtures of the first and second precursors are extruded to produce a filament and irradiated with UV light during the extrusion process.

Abstract: The invention concerns a device formed with several yarns (2) knitted together so as to constitute a cylindrical elongated knitted fabric, that is a knitted fabric wherein the yarns (2) forming the stitches intersect substantially at the radially inner zone of said knitted fabric. The invention also concerns a device for setting in place, in the corporeal duct to be treated, an occluding device (1), comprising a longitudinal tube designed to contain the occlusive device when the latter is inserted into the duct to be treated.

Abstract: Implants include a porous layer made from a composition including a compound wherein collagen is cross-linked to a glycosaminoglycan, the porous layer being optionally joined to a collagen film.

Abstract: The present disclosure relates to a method of forming fibers. First and second precursors, each possessing a core and at least one functional group known to have click reactivity, are mixed in a hopper. The mixed precursors are then extruded through an extrusion die to crosslink and produce a filament. Polymerization of the first and second precursors is catalyzed by transition metal ions.

Abstract: The present invention relates to a composite implant comprising: a prosthetic fabric having a first side and a second side, a non-porous film of bacterial cellulose secured to the first side of the fabric. The invention further relates to a method of making such an implant.

Abstract: The present invention relates to a medical device comprising: a reinforcing member; and bacterial cellulose on at least a portion of the reinforcing member. The invention also relates to a method for making such a medical device.

Abstract: The present invention relates to an implant comprising: a sheet of bacterial cellulose having a macro-pattern positioned on at least a portion thereof. The invention also relates to a method for making such an implant.

Abstract: The present invention relates to A bioresorbable implant comprising: a bioresorbable porous layer including a biopolymer foam and defining first pores, a bioresorbable porous three-dimensional mesh made from a microbial cellulose and defining second pores, wherein the bioresorbable porous layer is disposed in the bioresorbable porous three-dimensional mesh. The invention also relates to a method of making a bioresorbable implant.

Abstract: The present invention relates to an implant intended to replace or reinforce defective orthopaedic tissue, such as a tendon or ligament, comprising: a bioresorbable porous matrix based on a collagen sponge; a porous three-dimensional knit having a longitudinal direction, characterized in that: said porous matrix fills said three-dimensional knit said three-dimensional knit having two opposite faces, a front face and a rear face, connected to one another by a spacer, at least one of said front and rear faces has at least one weave of pillar stitch type in the longitudinal direction of said knit.

Abstract: The present invention relates to a medical device comprising a bacterial cellulose sheet having perforations. The invention further relates to a method of making such a medical device.

Abstract: The present invention relates to a method of forming an implantable medical device comprising: culturing polymer-producing bacteria preferably Acetobacter xylinum in the presence of a degradable support; and removing the degradable support to recover an implant having pores of a configuration determined at least in part by the configuration of the degradable support. The invention also relates to a medical device obtained by such a method.