Abstract: Disclosed are cells and cellular compositions useful for treatment of degenerative and/or autoimmune diseases derived from gene edited/gene modified pluripotent stem cells. In one embodiment pluripotent stem cell such as inducible pluripotent stem cells are gene modified to express tissue associated transcription factors such as pdx-1 if endodermal tissue is desired and cells are differentiated into regenerative-type cells such as along the mesenchymal lineage. In one embodiment the invention teaches transfection with IL-27 to induce expression of coinhibitory molecules for suppression of autoimmunity. In some embodiments the invention provides generation of iPSC derived MSC which can not stimulate inflammation due to gene-editing based removal of inflammatory associated transcription factors.

Abstract: A conveyance rollers pair includes a first roller and a second roller. The first roller has a uniform outer diameter and rotates around an axis. The second roller conveys a medium held between the first roller and the second roller while rotating around an axis. The second roller includes a shaft part, a plurality of columnar elastic members and a plurality of tube members. The shaft part extends in an axial direction and is supported rotatably around the axis. The elastic members are fixed to an outer circumferential surface of the shaft part at intervals in the axial direction. Each of the tube member has heat-shrinking property and water-repellency, adheres closely to an outer circumferential surface of the elastic member, and has both end portions which are protruded outward from both axial ends of the elastic member and have a diameter smaller than an outer diameter of the elastic member.

Abstract: A spade flange tool comprises a spade portion and a handle portion, wherein the spade portion includes a well for collecting fluids and wherein the handle portion includes a drain, in fluid communication with the well, for draining fluids collected in the well. The spade flange tool described herein is particularly useful for safely and effectively draining waste fluid effluent from cleaning operations used in onsite cleaning of equipment in industrial plants, such as vessels, tanks, conduits, etc., having a flanged connection. The spade flange tool may also be used to introduce a pressurizing fluid into equipment having a flanged connection.

Abstract: A die coater inspection device including: a sensor module configured to inspect a lip or the shim of the die coater; a control part configured to control an operation of the sensor module; and a storage part in which reference data on the thickness of the lip or the shim is stored.

Abstract: The present invention concerns an optoelectronic device D such as a Semiconductor optical amplifier (SOA) working in a continuous wave condition and able to amplify high frequencies optical signals. The optoelectronic device D comprise an active zone I (such as SOA) with a slab (3) in a direct bias working in a continuous wave and a taper zone (II) connected to the active zone (I).

Abstract: A cooling device includes a radiator, a tank, a circulation pipe, and a storage pool. The radiator dissipates heat of cooling medium. The tank stores the cooling medium. The circulation pipe allows the cooling medium to be conveyed from the radiator to the tank. The storage pool stores the cooling medium that has leaked from the tank. The tank includes a connector and a channel member. The connector connects the circulation pipe and the tank so that the circulation pipe communicates with an inside of the tank. The channel member guides the cooling medium leaking from the connector to the storage pool.

Abstract: A decoder includes circuitry configured to receive a bitstream, extract a header associated with a current frame and including a signal characterizing that global motion is enabled and further characterizing parameters of a global motion model, and decoding the current frame, the decoding including using a motion model for each current block having a complexity that is less than or equal to a complexity of the global motion model. Related apparatus, systems, techniques, and articles are also described.

Abstract: A network element includes an aggregate gateway function having a control plane and a separate user plane, wherein the network element is configured to: establish a plurality of first packet forwarding control protocol sessions for a plurality of packet data unit sessions between the residential gateway and the network, each of the plurality of first packet forwarding control protocol sessions hosting a set of data packet forwarding rules for a respective packet data unit session among the plurality of packet data unit sessions; and facilitate network access by the residential gateway according to the plurality of first packet forwarding control protocol sessions.

Abstract: The present disclosure relates to a slot die coating apparatus for coating an electrode active material slurry onto an electrode collector, the slot die coating apparatus including a coating roller, a die comprising a lower discharge opening, through which a first electrode active material slurry is discharged, and an upper die located on the upper side of the lower die and having an upper discharge opening, through which a second electrode active material slurry is discharged, and an upper air vent may be installed in the upper die and a lower air vent may be installed in the lower die.

Abstract: An apparatus for diagnosing a state of a battery includes a profile generating unit configured to generate a differential profile representing a corresponding relationship between a differential voltage representing a change rate of a voltage of a battery to a SOC of the battery and the SOC; and a control unit configured to calculate a curvature corresponding to a preset SOC region in the differential profile, compare the calculated curvature with a preset criterion curvature for the battery, and judge whether lithium is precipitated in the battery based on the comparison result.

Abstract: A method and apparatus for securing separate loops of suture with a coaxial mechanical fastener. Separate loops of suture extend from opposite ends of the mechanical fastener. A wire snare facilitates pulling the suture through the fastener. A suturing instrument provides for the infusion of pressurized physiologic solutions into the left ventricle so that the proper replacement suture length can be demonstrated real time prior to crimping the fastener. The instrument incorporates a slotted release site so that the fastener and suture can be released from the device tip once the fastener is secured. A method of securing suture coming from cardiac valve leaflets and or other structures like papillary muscles permits a more atraumatic orientation of the fastener coaxial with the suture strands.

Abstract: A method and apparatus for providing emergency assistance includes receiving audio, visual, or text data about an ongoing emergency at a public safety answering point, comparing that data to a database of other emergencies with an artificial intelligence engine, recognizing patterns in aggregated and correlated data by the artificial intelligence engine, and generating appropriate audio, visual, and text output for a human operator to respond to the emergency. An AI engine receives audio data, visual data, and text data related to ongoing emergencies being received at public safety answering points and compares it with data from other emergencies. The AI engine identifies key words and patterns and generates appropriate messages for operators. The system continuously generates feedback to the AI engine to aid in machine learning. The feedback includes: “the message was correct; continue drawing this conclusion”; and “the message was wrong; do not continue drawing this conclusion.

Abstract: An icemaker assembly includes a mold body defining a plurality of cavities. A working fluid line is directly attached to the mold body, and a drain duct is disposed below the mold body. A defrost heating element is positioned below the mold body and within the drain duct. The defrost heating element is spaced from the mold body, and the defrost heating element is operable to melt frost on the mold body with radiant heat from the defrost heating element. A related appliance is also provided.

Abstract: An imaging device having a superior light-shielding property for a charge-holding section is provided. The imaging device includes: an Si {111} substrate extending along a horizontal plane; a photoelectric conversion section provided in the Si {111} substrate and generating charges corresponding to a light reception amount by photoelectric conversion; a charge-holding section provided in the Si {111} substrate and holding charges transferred from the photoelectric conversion section; and a light-shielding section including a horizontal light-shielding part positioned between the photoelectric conversion section and the charge-holding section in a thickness direction and extending along the horizontal plane and a vertical light-shielding part orthogonal thereto.

Abstract: The present technology relates to a solid-state imaging device and an electronic apparatus capable of improving the accuracy of phase difference detection while suppressing degradation of a picked-up image. There is provided a solid-state imaging device including: a pixel array unit, a plurality of pixels being two-dimensionally arranged in the pixel array unit, a plurality of photoelectric conversion devices being formed with respect to one on-chip lens in each of the plurality of pixels, a part of at least one of an inter-pixel separation unit formed between the plurality of pixels and an inter-pixel light blocking unit formed between the plurality of pixels protruding toward a center of the corresponding pixel in a projecting shape to form a projection portion. The present technology is applicable to, for example, a CMOS image sensor including a pixel for detecting the phase difference.

Abstract: A laundry appliance includes a cabinet, a tub, and a pump for recirculating wash fluid from the tub to a filter container. The filter container includes a fluid inlet in fluid communication with the pump and fluid outlet in fluid communication with the tub. The filter container also includes a filter housing for directing wash fluid from the fluid inlet to the fluid outlet. A self-clearing filter assembly is provided within the filter housing. The self-clearing filter includes side walls and a filter base having at least one inclined surface. The self-clearing filter is situated such that the inclined surface is below the fluid inlet. The self-clearing filter prevents microfibers and other debris from passing through to the outlet of the filter container. Simultaneously, the force of the wash fluid on the inclined surface forces the microfibers and other debris to a trough, where it can be collected and disposed of.

Abstract: A system and method for data transmission and performance improvement for an appliance is provided. The system includes an appliance including a controller operably connected to a network computing device. The controller is configured to transmit a packet to a network computing device. The packet includes genealogical data for the appliance encoded in a positional numeral system. The network computing device is configured to receive the packet and decode the genealogical data for the appliance. Decoding includes translating the positional numeral system to an appliance configuration.

Abstract: The present disclosure relates to methods, apparatuses, and systems to measure one or more electrical signals from a cultured cell layer. In some embodiments, such electrical signals can be indicative of transport or lack of transport of an agent through the cell layer.

Abstract: A processing is executed with respect to a key value of a key field included in a sequence of one or more key fields expressing a received intent which is associated with a specific system. Based on a result of the processing, one or more instructions associated with the specific system are generated for one or more control functions controlling an infrastructure for carrying out the received intent.

Abstract: A lens module and an electronic device include a lens barrel and an optical component. The lens barrel includes a barrel wall and a clamping member protruding from a first inner side wall of the barrel wall. The clamping member includes a second inner side wall close to the optical axis. The second inner side wall of the clamping member is a sloped surface on a section paralleled to the optical axis, and the sloped surface is inclined from the object side to the image side toward a direction close to the optical axis. The clamping member is resisted against an outer side of the optical component. Thus, when the optical component is engaged with the clamping member, a single optical component can be smoothly fixed and arranged on the clamping member at the corresponding position.