Abstract: A securement device (100) for securing a lumen (12) of a medical device (14) includes a main body (110) configured to be detachably secured to a skin of a user. The main body includes a first body portion (112) including a first cavity surface (118) and a second body portion (142) including a second cavity surface (148) pivotally coupled to the first cavity surface. The first and second cavity surfaces together define a cavity (170). The securement device further includes an insert (180) fixedly coupled to the main body and at least partially received within the cavity. The insert includes a groove (184) configured to receive the lumen of the medical device. The main body is deformable between an open configuration and a closed configuration, and the insert is correspondingly deformable between a release state and a secure state. In the release state, the groove is configured to receive the lumen therein. In the secure state, the lumen is secured within the groove.

Abstract: Adhesive compositions are disclosed that include an octenidine salt, a resin system, a plasticizer, and a cidatrope. The dried adhesive compositions are substantially free of water and C2-C5 alcohols. The adhesive compositions disclosed are formulations that provide rapid and persistent antimicrobial activity and may be useful, for example, in wound dressings, surgical drapes, and medical tapes.

Abstract: An article, and method of use, wherein the article includes: a substrate; a cationic coating bound to the substrate, wherein the cationic coating includes a guanidinyl-containing polymer that is crosslinked on the substrate; wherein the guanidinyl-containing polymer is of the following Formula (I), wherein: R3 is a H, C1-C12(hetero)alkyl, C5-C12(hetero)aryl, or Polymer; each R4 is independently H, C1-C12(hetero)alkyl, or C5-C12(hetero)aryl; each R5 is H, C1-C12(hetero)alkyl, C5-C12(hetero)aryl, or N(R4)2; Polymer is a residue of an aminopolymer chain; m is 1 or 2; and x is an integer of at least 1; and wherein the guanidinyl-containing polymer is crosslinked with an amine-reactive polyepoxy compound having pendant —OH groups.

Abstract: Compositions including a quaternary amine antiseptic component having a concentration of at least about 0.04% by weight; a poly carboxylic acid chelator having a concentration of at least about 0.05 M and/or an alphahydroxy acid buffer having a concentration of at least about 0.05 M; a (C8-C12) 1,2 alkane diol; and optionally water are provided. The compositions have a pH greater than or equal to 3.5 and less than 5.5 at 23° C. In certain embodiments, water is present in the composition at a greater weight percent than each of the quaternary amine antiseptic component; the polycarboxylic acid chelator, if present; the alphahydroxy acid buffer, if present; and the (C8-C12) 1,2-alkane diol. In certain embodiments, water is present in the composition at a greater weight percent than any other component.

Abstract: The invention relates to a process of taking a dental impression, the process comprising the steps of providing a radiation-curable dental impression composition, placing the radiation-curable dental impression composition in contact with dental tissue, applying radiation to the radiation-curable dental impression composition, letting the radiation-curable dental impression composition cure, removing the cured dental impression composition from the dental tissue, the radiation-curable dental impression composition comprising mercapto-functional polyorganosiloxane(s), VQM resin(s), photo-initiator(s) for initiating a curing reaction between, and optionally filler(s). The invention also relates to a cured dental impression obtained by radiation curing the radiation-curable dental impression composition, a kit of parts containing the radiation-curable dental impression composition and a dental impression tray filled with the radiation-curable dental impression composition.

Abstract: The present disclosure provides wound dressing compositions that disrupt biofilm formation in a wound upon application. The wound dressing composition includes a first layer comprising a homogeneous mixture of a collagen, an oxidized regenerated cellulose (ORC), and at least one bacteria reducing active ingredient and a second layer comprising a homogeneous mixture of a collagen, an oxidized regenerated cellulose (ORC), a silver compound, and at least one bacteria reducing active ingredient, and the uses thereof. Also disclosed herein are kits comprising the wound dressing compositions of the present technology, and instructions for use.

Abstract: Methods for automatically removing collisions between digital mesh objects and moving digital mesh objects between spatial arrangements. The collisions are removed from a set of digital mesh objects using a perturbation method or a mesh deformation method. After removing the collisions, the digital mesh objects are output in a state without collisions between them. The digital mesh objects can be moved between initial and final states based upon motion constraints of the mesh objects and interpolated states of them between the initial and final states. Based upon the constraints and interpolated states, a number of states for movement of the set of digital mesh objects is determined either collectively for the set or individually for each mesh object. The states can be used as digital setups for dental or orthodontic treatment planning.

Abstract: Provided are adhesive articles that include a silicone adhesive and a substrate, with a primer layer interposed between the silicone adhesive and the substrate. The primer layer includes a polymer having a polyorganosiloxane pendant group P represented by the formula (I) where each R1 is independently an alkyl, haloalkyl, arylalkyl, alkenyl, aryl, or aryl substituted with an alkyl, alkoxy, or halo; R2 is an alkyl or an alkenyl group; R3 is an alkylene or an arylalkylene group; and n is an integer in the range of 1 to 20. The primer layer typically improves the adhesion between the silicone adhesive and a wide variety of substrates.

Abstract: A releasable medical drape, and systems and methods having the same, includes at least a liquid-impermeable, vapor-permeable layer, a pressure-sensitive adhesive layer, and a soft-gel layer having a plurality of apertures. The soft-gel layer is configured to be disposed adjacent to a tissue site. A portion of the pressure-sensitive adhesive layer extends through the plurality of apertures in the soft-gel layer to contact the tissue site. The soft-gel layer forms a good seal with the tissue site and the pressure-sensitive adhesive layer extending through the plurality of apertures forms a firm—but releasable—coupling with the tissue site.

Abstract: The invention relates to A curable composition for producing dental composite crowns, the composition comprising a resin matrix comprising polymerizable (meth)acrylate(s) not comprising a urethane moiety, polymerizable urethane(meth)acrylate(s), wherein the polymerizable (meth)acrylate(s) not comprising an urethane moiety are used in excess over the polymerizable urethane(meth)acrylate(s), a filler matrix comprising nanocluster(s), fumed silica in an amount below 8 wt. % with respect to the weight of the whole composition, an initiator system comprising photoinitiator(s), organic dye(s), the curable composition not comprising softener in an amount of more than 5 wt. % with respect to the weight of the whole composition, the curable composition having a viscosity below 150 Pa*s at 23° C. and a shear rate of 1 s?1. The invention also relates to a cured article obtained by radiation curing this curable composition by use of an additive-manufacturing method.

Abstract: A catheter fixer is disclosed that comprises a base (1) and wing fixing portions (2). The base comprises an adhering surface and a fixing surface (11), and the adhering surface is configured to adhere the base to the skin. The wing fixing portions are configured to detachably fix wings on the fixing surface. The wings of the catheter are fixed to the base through the wing fixing portions, and an adhesive tape is disposed on a side of the base facing the skin, such that the adhesive tape is prevented from being adhered to the catheter, thereby avoiding leaving adhesive tape residue on the catheter.

Abstract: In some illustrative examples, a bridge suitable for treating a tissue site may include a bridge sealing member and one or more bridge wicking layers. The bridge sealing member may extend along a length of the bridge, and may define an internal passageway in fluid communication between a receiving end of the bridge and a transmitting end of the bridge. The one or more bridge wicking layers may be disposed within the internal passageway of the bridge sealing member. Other apparatus, systems, and methods are disclosed.

Abstract: Adhesive articles include a substrate; and a hot melt processable pressure sensitive adhesive on the substrate. The hot melt processable pressure sensitive adhesive is a (meth)acrylate-based copolymer that is the reaction product of a reaction mixture that is free of acidic or basic monomers, and includes an alkyl (meth)acrylate, a hydroxyl-functional (meth)acrylate, and a photocrosslinker. The (meth)acrylate-based polymer is prepared in a thermoplastic package.

Abstract: This disclosure describes devices, systems, and methods related to a connection point of a therapy system which includes light switchable adhesive and is configured to be switched by light provided by and/or via one or more components of the therapy system. An example of a connection point is an interface between two tubes of therapy system. An example of light provided to the exemplary connection point is light provided to one of the two tubes such that the light travels to the connection point, via at least the one tube, to switch the light switchable adhesive.

Abstract: Systems, methods, and apparatuses for irrigating a tissue site are described. The system can include a tissue interface and a sealing member configured to be placed over the tissue site to form a sealed space, and a negative-pressure source fluidly coupled to the sealed space. The system includes an irrigation valve having a housing, a piston disposed in the housing, a fluid inlet to fluidly couple a fluid inlet chamber to a fluid source, and a fluid outlet to fluidly couple a fluid outlet chamber to the sealed space. A piston passage extends through the piston and fluidly couples the fluid inlet chamber and the fluid outlet chamber, and a biasing member is coupled to the piston to bias the irrigation valve to a closed position. The negative-pressure source is configured to move the piston between the closed position and an open position to draw fluid to the sealed space.

Abstract: The apparatus (1000) includes a housing (110), a chamber (120) disposed in the housing, at least two light emitting diodes (LEDs) (130) disposed within the housing (110), and a user interface (140) disposed on an exterior (112) of the housing. The chamber (120) is adaptable to each of an open, closed, and hermetically sealed configuration. The chamber (120) includes a material transparent to actinic radiation and light from the LEDs (130) enters the chamber from more than one direction. The user interface (140) includes a display (142) and program switches (144) configured to adjust at least three operational parameters of the apparatus. The apparatus (1000) further includes a vacuum pump (150) operatively coupled to the chamber (120). The system includes the apparatus (1000) and an article (180). An article includes layers of at least one photopolymerized crosslinked composition and a low extractable component content.

Abstract: A sterilization test pack may include a shell defining an indicator compartment having a volume; a channel extending between a compartment opening and an exterior opening, the channel being in fluid communication with the indicator compartment through the compartment opening and surrounding atmosphere being in fluid communication with the channel through the exterior opening such that the indicator compartment is in fluid communication with the surrounding atmosphere through the channel, the channel having a length measured between the compartment opening and the exterior opening and a hydraulic radius along the length; and an indicator disposed in the indicator compartment, where a ratio of the compartment volume to the channel hydraulic radius may range from 1000 cm2 to 8000 cm2.

Abstract: Aspects of the present disclosure provide for a patient warming system having a heating device configured to transfer heat to a patient based on a body heat score that indicates whether the patient is likely to sweat. The heating device includes a heater circuit configured to produce heat, the heater circuit thermally coupled to the patient. The heating device also includes a controller communicatively coupled to the heater circuit. The controller has one or more processors configured to receive one or more physiological indicators of the patient, determine the body heat score from one or more physiological indicators, determine whether the body heat score meets a score threshold, direct the heater circuit to produce a first amount of heat based on whether the body heat score meets a score threshold.