Abstract: A medical drape for use with a reduced pressure system for providing reduced pressure to a tissue site is described. In some embodiments, the drape may include a flexible film, and an adhesive layer coupled to the flexible film. The adhesive layer may include a first adhesive disposed on a first portion of the flexible film in a first pattern. The first adhesive can be configured to secure the flexible film proximate to the tissue site. The adhesive layer generally includes a second adhesive disposed on a second portion of the flexible film in a second pattern. The second adhesive can be configured to seal the flexible film proximate to the tissue site. The first pattern and the second pattern are preferably registered so that the first portion and the second portion are offset to cover substantially different portions of the flexible film.

Abstract: A dressing for managing an incision and surrounding tissue where edema and swelling may be present post-operation. The dressing may maximize coverage of area in articulating joints, such as a knee or elbow, while allowing for substantial range of motion. In some embodiments, the dressing may comprise an adhesive border configured to be adhered to skin around an articulating joint, a skin-interfacing fabric for minimizing skin irritation, a foam body for manifolding negative pressure and absorbing exudate and other body fluids, and a thin polymer film cap for sealing the assembly so negative pressure can be maintained throughout the dressing.

Abstract: The system comprises of a fluid container, a replaceable applicator head and a compatible, viscous antiseptic solution. The primary advantage is substantially drip free application. The system is non-vented and non-collapsible. The fluid container is non-compressible and comprises a prepping solution, a threaded spout and a container seal. The applicator head consists of a body to which a foam pad is attached and a channel through which the solution flows into the foam when the applicator head is connected to the fluid container. The applicator head when fixed onto the fluid container breaks the seal and creates a continuous channel that is non-vented for the solution to flow into the foam pad.

Abstract: A chromatography device having a housing formed from an upper housing ultrasonically welded to a lower housing. A compression extension and a boss located inside of the housing with the media disposed between the compression extension and the boss such that a perimeter of the media is compressed between the compression extension and the boss forming a liquid impermeable seal along the perimeter after the upper housing is ultrasonically welded to the lower housing.

Abstract: A customizable wound treatment system for treating multiple zones of a wound includes a dressing configured for use with a first zone and a second zone of a wound that includes a first foam layer placed over the first zone, a second foam layer placed over the second zone, a first drape layer disposed over the first foam layer and beneath the second foam layer, and a second drape layer disposed over the second foam layer. The customizable wound treatment system includes a negative pressure source pneumatically coupled to the first foam layer and the second foam layer and operable to create a negative pressure at the first zone and the second zone and a fluid instillation pump fluidly coupled to the first foam layer and configured to instill a treatment fluid to the first zone.

Abstract: New and useful systems, apparatuses, and methods for providing negative-pressure therapy with instillation of topical treatment solutions are described. An apparatus may comprise an exudate container, a solution source, and a pneumatically-actuated instillation regulator. The instillation regulator may be coupled to the exudate container and to the solution source, and negative pressure from a negative-pressure source can actuate the instillation regulator. In some embodiments, a negative-pressure source may be configured for a negative-pressure interval and a venting interval, and the instillation regulator can be configured to draw instillation solution from the solution source during a negative-pressure interval and to instill the solution to a dressing during a venting interval.

Abstract: The invention relates to an initiator system for curing a dental composition, the initiator system comprising a hydroperoxide component, a transition metal component, a polymerizable thiourea component, the polymerizable thiourea component comprising a thiourea moiety which is attached to a (meth)acrylate moiety through a C3-11 alkyl chain. The invention also relates to a dental composition comprising such an initiator system, and curable components, in particular curable components comprising acidic moieties.

Abstract: A liquid-collection canister includes a liquid collection chamber defined by at least one wall and a first and second gas-communication pathway formed within the at least one wall. A first aperture is positioned between the first gas-communication pathway and the liquid collection chamber to allow gaseous communication between the liquid collection chamber and the first gas-communication pathway. A second aperture is positioned between the second gas-communication pathway and the liquid collection chamber to allow gaseous communication between the liquid collection chamber and the second gas-communication pathway. A first and a second liquid-air separator are positioned over the first aperture and the second aperture, respectively, to substantially prevent liquid passing through the first and second apertures.

Abstract: An ultrasonic coupling device. The ultrasonic coupling device includes a foam having an aperture; a hydrogel wherein the hydrogel has a water content of at least 10 wt %, wherein at least part of the hydrogel locates in the aperture of the foam; and a near field communication device.

Abstract: A membrane having a first outer surface having a plurality of pores in a skin layer and the plurality of pores having a closed perimeter in the skin layer. The membrane having a second outer surface and a porous supporting layer connecting the first outer surface to the second outer surface. The first outer surface of the membrane is a melt-fused skin layer from exposure to ultra-violet light.

Abstract: A custom tool for forming a dental restoration in a mouth of a patient includes a one-piece mold body providing for a customized fit with at least one tooth of the patient, the one-piece mold body including an occlusal portion forming an occlusal surface corresponding with an occlusal surface of the tooth, a mesial proximal portion forming a mesial proximal surface corresponding with a mesial proximal surface of the tooth, and a distal proximal portion forming a distal proximal surface corresponding with a distal proximal surface of the tooth. The mold body is configured to combine with the tooth of the patient to form a mold cavity encompassing missing tooth structure of the tooth. The occlusal portion, the mesial proximal portion, and the distal proximal portion are based on three-dimensional scan data of the mouth of the patient.

Abstract: In some illustrative embodiments, a system suitable for treating a tissue site may include a dressing, a low-profile conduit, a conduit interface, and a reduced-pressure source. The dressing may be adapted for positioning at the tissue site. The low-profile conduit may be adapted for fluidly coupling to the dressing. The low-profile conduit may include a manifold and a sealing member encapsulating the manifold. The conduit interface may be adapted for fluidly coupling to the low-profile conduit. The conduit interface may be in fluid communication with the dressing through the low-profile conduit. The reduced-pressure source may be adapted for fluid communication with the conduit interface. Other systems, devices, and methods are disclosed.

Abstract: An evaporative bridge dressing that may be used with negative-pressure treatment of tissue. The evaporative bridge dressing may have one or more fluid transfer layers comprised of high-density wicking material enclosed between layers of film having high moisture-vapor transfer rates to reduce liquid storage and minimize pressure drop.

Abstract: Siloxane-based gel adhesives with improved shear holding power are prepared from curable compositions. The curable compositions include a siloxane fluid with a viscosity of at least 1,000,000 centiPoise, a siloxane-(meth)acrylate co-polymer, and siloxane tackifying resin. The curable compositions can contain an initiator or can be cured by e-beam radiation without an initiator. The siloxane-(meth)acrylate copolymer is the reaction product of a reaction mixture of an ethylenically unsaturated siloxane-containing macromer, an alkyl (meth)acrylate monomer; optionally a reinforcing monomer, and an initiator.

Abstract: A computer system automatically generates and provides real-time feedback to a healthcare provider about a selected Evaluation and Management (E/M) level to assign to a patient encounter. The system provides the feedback while the healthcare provider is creating the clinical note that documents the patient encounter. The system may also automatically generate and suggest E/M levels to the healthcare provider for approval by the healthcare provider while the healthcare provider is creating the clinical note.

Abstract: A wound dressing includes a patient interface layer, a wicking layer, an absorbent layer, and a cover layer. The patient interface layer is configured to engage a wound bed and has a first side and a second side, the second side configured to face the wound bed. The wicking layer, absorbent layer, and cover layer all also have a first side and a second side. A perimeter of the first side of the wicking layer is adhered to the second side of the cover layer, forming an adhesive border surrounding the wicking layer and the absorbent layer, and the wicking layer is configured to peripherally wick perspiration from underneath the adhesive border towards the center of the wicking layer and upwards towards the absorbent layer.

Abstract: The present disclosure provides a method of making an orthodontic article. The method includes (a) providing a photopolymerizable composition; (b) selectively curing the photopolymerizable composition using actinic radiation to form an article in the shape of an orthodontic article including a number of layers of at least one photopolymerized polymer; and (c) moving the article and thereby generating a mass inertial force in the uncured photopolymerizable composition. The article has a first surface, and no more than 75% of the first surface has a slope magnitude greater than 2.5 degrees. Orthodontic articles are also provided, including an orthodontic article that is prepared according to the method. Orthodontic articles having low extractable component content are further provided. The mass inertial force tends to form a coating layer of uncured photopolymerizable composition on the article, and curing the coating layer can form a surface having low slope magnitude.

Abstract: Aspects of the present disclosure relate to a self-mating fastener that includes a backing having a first side, and a rail element protruding perpendicularly from the first side of the backing. The rail element extends in a longitudinal direction along the backing. The rail element has a base portion attached to the first side of the backing and a cap portion distal from the backing. The cap portion has a cap width that is greater than a width of the base portion and the cap portion overhangs the base portion on opposing sides. The self-mating fastener includes an electrically conductive contact element proximate to the rail element.

Abstract: The invention relates to a glazing composition for a porous dental zirconia article, the glazing composition comprising liquid, glass particles, fluorescing component(s) comprising europium, optionally hydrophilic silica nano-particles, and optionally hydrophobic silica nano-particles, wherein the fluorescing component(s) can be contained in the glass particles or as separate component. The invention also relates to a process for sintering a porous dental zirconia article with a glazing composition on its surface.

Abstract: A self-contained biological sterilization indicator comprises: a housing; bacterial spores comprising, and/or capable of producing, an enzyme capable of catalyzing cleavage of an enzyme substrate; and a frangible container containing a composition, wherein the composition comprises the enzyme substrate, wherein if the frangible container is broken the composition will contact the bacterial spores to form a mixture having an initial pH in the range from 6.0 to 9.0. The enzyme substrate comprises a fluorinated 4?-alkylumbelliferyl ?-D-glucopyranoside represented by the structural formula (I) wherein one of R1 and R2 is F and the other is H, and R3 is an alkyl group having from 1 to 12 carbon atoms. A biological sterilization indicator comprising a kit containing isolated components comprising (i) bacterial spores comprising, and/or capable of producing, an enzyme capable of catalyzing cleavage of the enzyme substrate and a method of assessing efficacy of a sterilization process are also disclosed.