Patents Assigned to SOOCHOW UNIVERSITY
  • Patent number: 11261222
    Abstract: A transdermal peptide with a nuclear localization ability and having an amino acid sequence as shown in SEQ ID NO: 1 is disclosed. A fusion protein including a macromolecular protein with one end being linked to the transdermal peptide is also disclosed. The transdermal peptide can be used in the preparation of a medicament or a transdermal preparation for treating skin diseases. A medicament for treating a skin disease includes the transdermal peptide and a pharmaceutically acceptable excipient. The transdermal peptide enters the cells autonomously to locate in the nuclei, and can penetrate through the stratum corneum of the skin into cells in the dermis. The peptide is conveniently synthesized artificially and suitable for transdermal administration, and has a therapeutic potential via transdermal administration by carrying a drug for treating skin diseases.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: March 1, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Shuyu Zhang, Jianping Cao, Daojiang Yu, Wei Zhu
  • Patent number: 11232571
    Abstract: The present invention discloses a method and device for quick segmentation of an optical coherence tomography image, a computing device, and a computer readable storage medium. The method includes: extracting a feature value related to a pixel in the optical coherence tomography image from the pixel to obtain a feature value representative of the pixel feature, the feature value including at least one of an intensity gradient value of the pixel, an intensity multi-scale mean value of the pixel, and an angular feature value extracted from the pixel; inputting the feature value into a Sparse Bayesian Classification model containing values related to image features corresponding to a border, to obtain a probability that the image feature belongs to features of various image region borders; and obtaining borders of various image regions contained in a predefined image region based on the probabilities obtained for various pixels in the predefined image region.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: January 25, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Lirong Wang, Meng Gan, Cong Wang
  • Patent number: 11224866
    Abstract: The invention discloses a visible light responsive tricobalt tetraoxide dodecahedron/carbon nitride nanosheet composite and an application thereof in exhaust gas treatment. The preparation method of the composite comprises the following steps: with urea as a precursor, carrying out twice calcination to obtain carbon nitride nanosheet; dispersing the carbon nitride nanosheet into methanol, sequentially adding cobalt nitrate hexahydrate and 2-methylimidazole, and carrying out a reaction to obtain a carbon nitride nanosheet composite; and calcining the carbon nitride nanosheet composite in an air atmosphere at a low temperature to obtain the tricobalt tetraoxide dodecahedron/carbon nitride nanosheet composite.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: January 18, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Jianmei Lu, Dongyun Chen
  • Patent number: 11224970
    Abstract: A large area surveillance method is based on weighted double deep Q-learning. A robot which of Q-value table including a QA-value table and QB-value table is provided, an unidentified object enters a large space to trigger the robot, and the robot perceives a current state s and determines whether the current state s is a target state, if yes, the robot reaches a next state and monitors the unidentified object, and if not, the robot reaches a next state, obtains a reward value according to the next state, selectively updates a QA-value or QB-value with equal probability, and then updates a Q-value until convergence to obtain an optimal surveillance strategy. The problems of a limited surveillance area and camera capacity are resolved, and the synchronization of multiple cameras doesn't need to be considered, and thus the cost is reduced. A large area surveillance robot is also disclosed.
    Type: Grant
    Filed: April 8, 2018
    Date of Patent: January 18, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Zongzhang Zhang, Zhiyuan Pan, Hui Wang
  • Patent number: 11228259
    Abstract: The present invention relates to an energy harvester, including: a base; an electromagnetic coil fixed in the base; a disk-shaped stator magnet fixed at the center of the base; a friction plate fixing ring fixed on the base; at least one friction plate unit fixed on an inner side surface of the friction plate fixing ring; a disk-shaped rotor magnet whose bottom is in contact with the electromagnetic coil, wherein the disk-shaped rotor magnet is attracted and held to the disk-shaped stator magnet, and an outer surface of the disk-shaped rotor magnet is tangent to an outer surface of the disk-shaped stator magnet; and an annular friction plate fixed on the disk-shaped rotor magnet, wherein the annular friction plate and a friction plate are made of materials with different polarities. The foregoing energy harvester has a simple structure and high electrical energy output efficiency.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: January 18, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Tao Chen, Zhan Yang, Huicong Liu, Lining Sun
  • Patent number: 11207670
    Abstract: The invention discloses a loaded multifunctional catalysis composite material, a preparation method thereof and an application of the composite material to catalytic removal of water pollutants. The preparation method includes the steps: preparing a zinc oxide nano-sheet loaded nickel foam (Ni@ZnO) composite material by an electro-deposition method; compounding molybdenum disulfide micro-nano particles on ZnO porous nano-sheets by an electro-deposition method to obtain Ni@ZnO/MoS2. The composite material Ni@ZnO/MoS2 combines the advantages of components such as nickel foam, the zinc oxide nano-sheets and molybdenum disulfide from the point of material performances, high catalytic degradation activity and recycled performances are achieved, photo-catalysis and electro-catalysis are combined from the point of material application, and the catalytic activity of the composite material is improved by the aid of synergistic effects of photo-catalysis and electro-catalysis.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: December 28, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Jianmei Lu, Najun Li
  • Patent number: 11201815
    Abstract: The invention relates to a method and system for selecting a least-loaded route based on a naive Bayes classifier, so that the performance of a method for selecting a least-loaded route is improved. A network snapshot records historical network status information, and a naive Bayes classifier is used to predict the potential future network blocking probability if a service connection is established along a candidate route between each node pair. A network snapshot corresponds to each service request that arrives, and records the number of busy capacity units on each link.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: December 14, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Gangxiang Shen, Longfei Li, Ya Zhang
  • Patent number: 11198112
    Abstract: The invention discloses a dinuclear rhodium complex-doped platinum/hollow mesoporous silica sphere composite material, and a preparation method and an application thereof. The preparation method comprises the following steps: preparing hollow mesoporous silica by a selective etching technology, uniformly distributed a precious metal platinum in the channels of the hollow mesoporous silica by using simple impregnation, and mixing the obtained catalyst with dinuclear rhodium complex adsorbed silica gel to obtain the composite material integrating a chromogenic probe with the catalyst.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: December 14, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Jianmei Lu, Dongyun Chen
  • Patent number: 11192093
    Abstract: A preparation method of a two-dimensional nitrogen-doped carbon-based titanium dioxide composite material includes: (1) etching Ti3AlC2 with LiF/HCl to prepare two-dimensional transition metal carbide nanosheet; (2) preparing a nanosheet aggregate by electrostatic self-assembly of a two-dimensional transition metal carbide nanosheet and a positively charged nitrogen-containing cationic compound; (3) calcining the nanosheet aggregates to prepare a two-dimensional nitrogen-doped carbon-based titanium dioxide composite material.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: December 7, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Jianmei Lu, Najun Li
  • Patent number: 11193000
    Abstract: This invention provides a self-healable epoxy resin and its preparation, recycling and remolding method. With the catalyst of potassium iodide, an ester solution of 2-mercaptoacetic acid was oxidated by 30% H2O2 to form 2,2?-dithiodiacetic acid; then 2,2?-dithiodiacetic acid was dehydrated and cyclizated by anhydride to form 1,4,5-oxadithiepane-2,7-dione; 1,4,5-oxadithiepane-2,7-dione and methylhexahydrophthalic anhydride were mixed by mass ratio and cured with epoxides to get the self-healable epoxy resin. Through controlling dynamic and permanent three-dimensional crosslinked network, the self-healable epoxy resins provided in this invention exhibit high thermal resistance and improved mechanical properties as well as excellent self-healing ability, recyclability and remoldability. This invention provides a preparation method with the merits of low cost, simple production processes, broad application prospects and strong utility.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: December 7, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Guozheng Liang, Youhao Zhang, Aijuan Gu, Li Yuan
  • Patent number: 11193024
    Abstract: The invention discloses a special-purpose reactive disperse dye for waterless dyeing of natural fibers in supercritical CO2 fluid and an intermediate thereof. The reactive disperse dye has a longer alkane-chain bridging group between a chromophoric parent structure and an active group of the dye, which effectively promotes the donating-withdrawing effect on the electron cloud in the conjugated system, enhances the hyperchromic effect, effectively reduce the influence of the active group itself and its reaction on the dye coloring system, improves the color and stability against acid and alkali of the dye, and facilitate the improvement of the compatibility of the dye with supercritical fluid and the dyeing performance for natural fibers as well. The invention also discloses an intermediate of the reactive disperse dye, and a method for preparing the reactive disperse dye.
    Type: Grant
    Filed: November 23, 2018
    Date of Patent: December 7, 2021
    Assignees: SOOCHOW UNIVERSITY, JIANGSU DANMAO TEXTILE CO., LTD., NANTONG TEXTILE AND SILK INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Jiajie Long, Kai Yan, Dao Xu, Jinlin Yu
  • Patent number: 11180437
    Abstract: Disclosed is a method for preparing a 1,3-dicarbonyl compound based on a metal hydride/palladium compound system. The method includes the following steps: suspending a palladium compound and a metal hydride in a solvent under the protection of nitrogen, then adding an electron-deficient olefin compound, reacting same at 0° C.-100° C. for 0.3 to 10 hours, then adding a saturated ammonium chloride aqueous solution to stop the reaction, and then subjecting same to extraction, evaporation until dryness, and column chromatography purification to obtain the 1,3-dicarbonyl compound. The hydride and palladium compound catalysts used by the present invention are reagents easily obtained in a laboratory. Compared to a common hydrogen hydrogenation method, the method is easier to operate, and has a higher safety, mild conditions, and a high reaction yield.
    Type: Grant
    Filed: March 16, 2021
    Date of Patent: November 23, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Shilei Zhang, Yujian Mao
  • Patent number: 11174164
    Abstract: Disclosed are a honeycomb-like homo-type heterojunction carbon nitride composite material and a preparation method thereof, and an application of the honeycomb-like homo-type heterojunction carbon nitride composite material in catalytic treatment of waste gas. The preparation method includes the following steps: with two different carbon nitride precursors namely urea and thiourea as raw materials, weighing certain amounts of the urea and the thiourea, adding the urea and the thiourea into a crucible, adding a certain amount of ultrapure water, placing the crucible in a muffle furnace, and carrying out calcination molding. The honeycomb-like homo-type heterojunction carbon nitride prepared by the one-step method has good photocatalytic effect to catalytic degradation of NO; meanwhile, the honeycomb-like homo-type heterojunction carbon nitride composite material has the advantages of rich and easily-available production raw materials, good stability, reusability, etc.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: November 16, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Jianmei Lu, Dongyun Chen, Jun Jiang
  • Patent number: 11177876
    Abstract: The invention relates to a method for setting and operating redundant paths in a quantum communication network, wherein a transmitter implements simultaneous transmission of signals on a working path and protection paths. The signal transmitted on the working path is a primary signal, and the signals transmitted on the protection paths are follow-up signals. In a case that the working path is normal, the transmitter forwards the primary signal on the working path level by level, to implement long distance transmission of a quantum signal. In a case that the working path fails, a proxy working path is selected from the remaining protection paths with the highest priority, and the transmission of information is eventually completed on the proxy working path. It can be prevented that unknown quantum information is damaged and becomes unrecoverable during transmission, thereby greatly improving the security, stability, and reliability of information transmission during quantum communication.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: November 16, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Min Jiang, Tao Cai, Zhixin Xia, Qing Li
  • Patent number: 11167274
    Abstract: The present invention provides an In—NH2/g-C3N4 nanocomposites with visible-light photocatalytic activity and application thereof, which can effectively remove organic pollutants (such as tetracycline) in water. First, the graphite phase carbonitride carbon (g-C3N4) was obtained by thermal condensation, and g-C3N4 nanosheet was prepared by thermal oxidative etching. Then, acicular MIL-68(In)—NH2 (In—NH2) was grown in situ on the surface of g-C3N4 nanosheet by solvothermal method. The In—NH2/g-C3N4 nanocomposites with high visible-light photocatalytic activity were obtained. The CNNS firstly was prepared in the present invention, which is beneficial to the needle-like In—NH2 growing on the surface of CNNS and having close interfacial contact with each other, forming a heterojunction, promoting the separation of photogenerated electrons and holes pairs, and enhancing visible-light photocatalytic degradation of organic pollutants.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: November 9, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Jianmei Lu, Qingfeng Xu
  • Patent number: 11145850
    Abstract: The invention provides a neural electrode, including a current generation device, a first and a second electrode. The current generation device is connected to the first and second electrodes through a conductive metal wire respectively. At least one of the first and second electrodes is a graphene electrode. The graphene electrode has soft texture and desirable stability to tolerate the repeated pressing and folding treatment, very high charge injection efficiency, and desirable in vivo stability, and is configured to electrically stimulate tissues and organs such as hearts and nerves to promote electrical stimulation and repair of neurons, to further promote regeneration of neural functions. The invention further provides use of a mineralized three-dimensional porous graphene foam material to prepare a bone defect filler. The bone defect filler has desirable biological compatibility, promotes cell proliferation, and accelerates and induces osteogenic differentiation of bone marrow mesenchymal stem cells.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: October 12, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Judong Luo, Qi Zhang, Yuyou Qiu, Shuyu Zhang, Qin Song, Guangyu Tang, Jianping Cao, Hua Jiang
  • Patent number: 11121775
    Abstract: The present invention discloses a method of rearrangement of optical amplifiers in a fiber-upgraded elastic optical network, including: traversing through the amplifiers on the upgraded link through a redundancy removal process to remove redundant EDFAs from the upgraded link and calculating the cost saved by the redundancy removal process; rearranging the amplifiers on the upgraded link through a full rearrangement process to rearrange all the EDFAs on the upgraded link and calculating the cost saved by the full rearrangement process; comparing the cost saved by the redundancy removal process with the cost saved by the full rearrangement process on the upgraded link and selecting a process that saved more costs as the method of rearrangement of optical amplifiers on the upgraded link; and perform rearrangement of optical amplifiers on all the upgraded links sequentially. This method can minimize the number of optical amplifiers without significantly reducing spectrum resource utilization.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: September 14, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Gangxiang Shen, Yongcheng Li, Ningning Guo
  • Patent number: 11118988
    Abstract: A method for calculating an earth pressure load on a tunnel includes the following steps: (1) taking interaction between external soil and a tunnel structure in an actual operation condition as an earth pressure load acting on the tunnel structure; (2) establishing a physical model for the tunnel structure; (3) designing, on the basis of the physical model for the tunnel structure, a plurality of structural loads in different operation conditions to obtain a plurality of different structural deformations; and (4) drawing an inference according Betti's theorem, and establishing a physical model for an original structure, such that a load on the original structure, namely an earth pressure load on the tunnel, can be directly calculated according to a load-deformation relationship of the physical model and deformation of the original structure. The above method can determine distribution and size of an actual earth pressure load on a tunnel.
    Type: Grant
    Filed: November 12, 2016
    Date of Patent: September 14, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventor: Pan Li
  • Patent number: 11120930
    Abstract: The present invention discloses a method for manufacturing a high-sensitivity piezoresistive sensor using a multi-level structure design, including the following steps: forming first-level basic geometrical units formed of basic structural units on a substrate, where each first-level basic geometrical unit is a two-dimensional or three-dimensional network structure formed by stacking several basic structural units; stacking and combining several first-level basic geometrical units in an array to form a second-level geometrical structure, and forming a contact connection area located between adjacent first-level basic geometrical units; and dispensing a conductive adhesive in at least two positions on the substrate to form electrodes of a piezoresistive sensor, so as to obtain the piezoresistive sensor.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: September 14, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Tao Liu, Xiaoshuang Duan, Jiangjiang Luo, Yanbo Yao
  • Patent number: 11084027
    Abstract: A method of preparing a three-dimensional composite material includes the following steps: preparing polystyrene by soap-free emulsion polymerizing, obtaining polystyrene opal by a vertical deposition method, synthesizing MoP IO (molybdenum phosphide inverse opal), and compounding with quantum points CdS, so as to obtain a novel inorganic composite material, namely cadmium sulfide quantum dot-compounded MoP IO. The preparation method has the advantages that the MoP IO is prepared first, and the MoP IO is of a three-dimensional cyclic pore structure and has the photonic band gap feature, so that the MoP IO has better catalysis effect in light catalysis in comparison with that of common porous material; the MoP IO is compounded with the cadmium sulfide quantum dots, so that the light absorbing ability is enhanced, and the composite material capable of absorbing the visible light is obtained.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: August 10, 2021
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Jianmei Lu, Najun Li