Patents Assigned to SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY
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Patent number: 9701603Abstract: The invention discloses a new strepsesquitriol A, a preparation method thereof and an application thereof. Strepsesquitriol A, a structure as shown in Formula (I), is a compound having a new skeleton and strongly inhibiting the formation of LPS-induced TNF? but showing no cytotoxic activity, so it can be used for the preparation of anti-inflammatory drug or act as a precursor of anti-inflammatory drugs, for the treatment of multiple inflammations. Therefore, the invention provides a new candidate compound for the development of anti-inflammatory drugs, and is of great significance for developing Chinese marine drug resources.Type: GrantFiled: December 30, 2013Date of Patent: July 11, 2017Assignee: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCESInventors: Xianwen Yang, Kun Peng, Sumei Li, Gaiyun Zhang, Jie Li, Xiuping Lin, Yonghong Liu
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Publication number: 20170142941Abstract: The present invention discloses a breeding method for obtaining heterosis in lined seahorses, which comprises the following steps: S1, selecting parents of lined seahorse from populations with great differences in genetic background; S2, intensified rearing the parents before pregnancy; S3, matching and breeding the parents of lined seahorse from different geographical populations according to complete diallel cross method; S4, finely nursing pregnant seahorses; S5, respectively collecting all postlarvae (filial generations) hatched by each breeding group in one week; S6, rearing the filial generations; and S7, comparing survival rate and growth performance of filial generations. The present invention, via hybridization of different geographical populations to obtain lined seahorse, makes effective use of heterosis. Survival rate and growth rate of filial generations are apparently enhanced compared to that of those filial generations without hybridization.Type: ApplicationFiled: December 4, 2015Publication date: May 25, 2017Applicant: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGYInventors: Wei LUO, Qiang LIN, Geng QIN, Xin WANG, Yanhong ZHANG, Huixian ZHANG
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Publication number: 20170131432Abstract: A pop-up monitoring base station for seafloor heat flow includes a recovery unit, a discarding unit and a cable chopping mechanism. The recovery unit includes a recovery support, internally accommodating two acoustic release devices provided with closable hooks on bottoms thereof and loaded with floating balls. The discarding unit includes a discarding support, below which a heat flow probe is fixedly connected. The recovery unit and the discarding unit are fixed together through a steel wire rope with two ends connected with the closable hooks at the bottoms of the acoustic release devices. A cable extends from the discarding unit through the cable chopping mechanism fixed on the bottom of the recovery support and connects with the floating balls. The cable can be chopped off and/or pulled out automatically to realize successful separation between the recovery unit and the discarding unit.Type: ApplicationFiled: December 29, 2015Publication date: May 11, 2017Applicant: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCESInventors: Xiaoqiu Yang, Zhaohua Sun, Xin Zeng, Xiaobin Shi
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Publication number: 20170105392Abstract: An method for selective breeding of a fast-growing strain of lined seahorse, including: (1) selecting high-quality lined seahorse parents as a base population for selective breeding; (2) performing prenatal intensified breeding; (3) performing pairing and mating, and rearing the juveniles thereof; (4) performing selective breeding in three junctures with different selection proportions; (5) pairing the saved adult lined seahorses, wherein those with low vitality, having injuries on the body surface, or having a dysplastic brood pouch or gonad are culled, and a selection proportion of 10% for every generation is maintained thereafter; (6) repeating steps (2) through (5) for at least four times to obtain a high-quality strain of lined seahorse with improved weight and body length and stable growth. The method can be used for selective breeding of a new strain with high quality and high yield.Type: ApplicationFiled: June 15, 2015Publication date: April 20, 2017Applicant: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE A CADEMY OF SCIENCESInventors: Qiang LIN, Wei LUO, Geng QIN, Huixian ZHANG, Yanhong ZHANG
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Publication number: 20160368846Abstract: The invention discloses a new strepsesquitriol A, a preparation method thereof and an application thereof. Strepsesquitriol A, a structure as shown in Formula (I), is a compound having a new skeleton and strongly inhibiting the formation of LPS-induced TNF? but showing no cytotoxic activity, so it can be used for the preparation of anti-inflammatory drug or act as a precursor of anti-inflammatory drugs, for the treatment of multiple inflammations. Therefore, the invention provides a new candidate compound for the development of anti-inflammatory drugs, and is of great significance for developing Chinese marine drug resources.Type: ApplicationFiled: December 30, 2013Publication date: December 22, 2016Applicant: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE A CADEMY OF SCIENCESInventors: Xianwen Yang, Kun Peng, Sumei Li, Gaiyun Zhang, Jie Li, Xiuping Lin, Yonghong Liu
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Publication number: 20160333687Abstract: An in-situ and on-line acoustic measuring system for natural gas flux at the hydrocarbon seeps at a seafloor includes a seepage tent and a flow measuring channel. The flow measuring channel includes a lower bubble breaking channel, an ultrasonic transducer measuring channel and an upper bubble breaking channel. The lower bubble breaking channel communicates with the seepage tent provided with bubble breaking grids. Lower and upper bubble breaking devices, arranged in a bubble rising direction, are respectively mounted in the lower and upper bubble breaking channels. One side of the ultrasonic transducer measuring channel is fixedly connected with an acoustic wave demultiplexer, and the other side is fixedly connected with flat receiving transducers receiving transmitting acoustic waves generated by an acoustic wave branching unit.Type: ApplicationFiled: February 5, 2015Publication date: November 17, 2016Applicants: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY CHINESE ACADEMY OF SCIENCES, GUANGDONG UNIVERSITY OF TECHNOLOGYInventors: Pengfei Di, Jianjun Long, Daxin Long, Linying Chen, Dong Feng, Duofu Chen
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Patent number: 9322040Abstract: The invention discloses a Pseudonocardia sp. and a method for preparing Deoxynyboquinone by utilizing the same. Pseudonocardia sp. SCSIO 01299 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011255 on Jul. 18, 2011. The Pseudonocardia sp. SCSIO 01299 can produce antibiotic Deoxynyboquinone, so that the Pseudonocardia sp. SCSIO 01299 can be utilized for preparing Deoxynyboquinone and a new way is provided for producing antibiotic Deoxynyboquinone with anti-tumor activity.Type: GrantFiled: September 1, 2011Date of Patent: April 26, 2016Assignee: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCESInventors: Si Zhang, Changsheng Zhang, Xinpeng Tian, Sumei Li, Wenjun Zhang, Haibo Zhang, Guangtao Zhang, Hao Yin, Jianhua Ju
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Patent number: 9200301Abstract: The invention discloses marine Streptomyces sp., a Pyranosesquiterpene compound, as well as a preparation method and uses thereof. Streptomyces sp. SCSIO 01689 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011257 on Jul. 18, 2011. The Streptomyces sp. SCSIO 01689 can produce the Pyranosesquiterpene compound with better anti-Escherichia coli activity and anti-Artemia activity, as well as Cyclo(D)-Pro-(D)-Ile, Cyclo(D)-Pro-(D)-Leu and Cyclo(D)-trans-4-OH-Pro-(D)-Phe with better anti-Vibrio anguillarum activity and anti-Artemia activity, thereby providing a new way for preparing the Cyclo(D)-Pro-(D)-Ile, the Cyclo(D)-Pro-(D)-Leu and the Cyclo(D)-trans-4-OH-Pro-(D)-Phe. The Pyranosesquiterpene compound can be used for preparing anti-Escherichia coli medicaments and anti-Artemia medicaments, as well as preparing condiments as a condiment precursor compound.Type: GrantFiled: August 16, 2012Date of Patent: December 1, 2015Assignee: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCESInventors: Lijuan Long, Xinpeng Tian, Jie Li, Xiongming Luo, Zhenxiong Qi, Tuan Yin, Hao Yin, Jian Yang
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Publication number: 20150306025Abstract: Provided herein is a bee venom composition with effects of protecting and beautifying lips, comprising cosmetic matrix components for use on lips and bee venom. The bee venom is prepared by using the following method: crude bee venom is dissolved with water, before ultrafiltrated using an ultrafiltration membrane with the molecular weight cutoff 10000 Da, and then the resulting filtrate is freeze-dried to obtain the bee venom.Type: ApplicationFiled: January 24, 2013Publication date: October 29, 2015Applicant: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCESInventors: Hua CHEN, Huili SUN, Si ZHANG, Jianyu PAN, Bingna CAI, Xiaoyu SUN
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Publication number: 20130316408Abstract: The invention discloses marine Streptomyces sp., a Pyranosesquiterpene compound, as well as a preparation method and uses thereof. Streptomyces sp. SCSIO 01689 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011257 on Jul. 18, 2011. The Streptomyces sp. SCSIO 01689 can produce the Pyranosesquiterpene compound with better anti-Escherichia coli activity and anti-Artemia activity, as well as Cyclo(D)-Pro-(D)-Ile, Cyclo(D)-Pro-(D)-Leu and Cyclo(D)-trans-4-OH-Pro-(D)-Phe with better anti-Vibrio anguillarum activity and anti-Artemia activity, thereby providing a new way for preparing the Cyclo(D)-Pro-(D)-Ile, the Cyclo(D)-Pro-(D)-Leu and the Cyclo(D)-trans-4-OH-Pro-(D)-Phe. The Pyranosesquiterpene compound can be used for preparing anti-Escherichia coli medicaments and anti-Artemia medicaments, as well as preparing condiments as a condiment precursor compound.Type: ApplicationFiled: June 18, 2012Publication date: November 28, 2013Applicant: South China Sea Institute Of Oceanology, Chinese Academy of SciencesInventors: Lijuan Long, Xinpeng Tian, Jie Li, Xiongming Luo, Zhenxiong Qi, Tuan Yin
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Publication number: 20130230890Abstract: The invention discloses a Pseudonocardia sp. and a method for preparing Deoxynyboquinone by utilizing the same. Pseudonocardia sp. SCSIO 01299 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011255 on Jul. 18, 2011. The Pseudonocardia sp. SCSIO 01299 can produce antibiotic Deoxynyboquinone, so that the Pseudonocardia sp. SCSIO 01299 can be utilized for preparing Deoxynyboquinone and a new way is provided for producing antibiotic Deoxynyboquinone with anti-tumor activity.Type: ApplicationFiled: September 1, 2011Publication date: September 5, 2013Applicant: South China Sea Institute of Oceanology, Chinese Academy of SciencesInventors: Si Zhang, Changsheng Zhang, Xinpeng Tian, Sumei Li, Wenjun Zhang, Haibo Zhang, Guangtao Zhang, Hao Yin, Jianhua Ju