Patents Assigned to SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY
  • Patent number: 9701603
    Abstract: The invention discloses a new strepsesquitriol A, a preparation method thereof and an application thereof. Strepsesquitriol A, a structure as shown in Formula (I), is a compound having a new skeleton and strongly inhibiting the formation of LPS-induced TNF? but showing no cytotoxic activity, so it can be used for the preparation of anti-inflammatory drug or act as a precursor of anti-inflammatory drugs, for the treatment of multiple inflammations. Therefore, the invention provides a new candidate compound for the development of anti-inflammatory drugs, and is of great significance for developing Chinese marine drug resources.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: July 11, 2017
    Assignee: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Xianwen Yang, Kun Peng, Sumei Li, Gaiyun Zhang, Jie Li, Xiuping Lin, Yonghong Liu
  • Publication number: 20170142941
    Abstract: The present invention discloses a breeding method for obtaining heterosis in lined seahorses, which comprises the following steps: S1, selecting parents of lined seahorse from populations with great differences in genetic background; S2, intensified rearing the parents before pregnancy; S3, matching and breeding the parents of lined seahorse from different geographical populations according to complete diallel cross method; S4, finely nursing pregnant seahorses; S5, respectively collecting all postlarvae (filial generations) hatched by each breeding group in one week; S6, rearing the filial generations; and S7, comparing survival rate and growth performance of filial generations. The present invention, via hybridization of different geographical populations to obtain lined seahorse, makes effective use of heterosis. Survival rate and growth rate of filial generations are apparently enhanced compared to that of those filial generations without hybridization.
    Type: Application
    Filed: December 4, 2015
    Publication date: May 25, 2017
    Applicant: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY
    Inventors: Wei LUO, Qiang LIN, Geng QIN, Xin WANG, Yanhong ZHANG, Huixian ZHANG
  • Publication number: 20170131432
    Abstract: A pop-up monitoring base station for seafloor heat flow includes a recovery unit, a discarding unit and a cable chopping mechanism. The recovery unit includes a recovery support, internally accommodating two acoustic release devices provided with closable hooks on bottoms thereof and loaded with floating balls. The discarding unit includes a discarding support, below which a heat flow probe is fixedly connected. The recovery unit and the discarding unit are fixed together through a steel wire rope with two ends connected with the closable hooks at the bottoms of the acoustic release devices. A cable extends from the discarding unit through the cable chopping mechanism fixed on the bottom of the recovery support and connects with the floating balls. The cable can be chopped off and/or pulled out automatically to realize successful separation between the recovery unit and the discarding unit.
    Type: Application
    Filed: December 29, 2015
    Publication date: May 11, 2017
    Applicant: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Xiaoqiu Yang, Zhaohua Sun, Xin Zeng, Xiaobin Shi
  • Publication number: 20170105392
    Abstract: An method for selective breeding of a fast-growing strain of lined seahorse, including: (1) selecting high-quality lined seahorse parents as a base population for selective breeding; (2) performing prenatal intensified breeding; (3) performing pairing and mating, and rearing the juveniles thereof; (4) performing selective breeding in three junctures with different selection proportions; (5) pairing the saved adult lined seahorses, wherein those with low vitality, having injuries on the body surface, or having a dysplastic brood pouch or gonad are culled, and a selection proportion of 10% for every generation is maintained thereafter; (6) repeating steps (2) through (5) for at least four times to obtain a high-quality strain of lined seahorse with improved weight and body length and stable growth. The method can be used for selective breeding of a new strain with high quality and high yield.
    Type: Application
    Filed: June 15, 2015
    Publication date: April 20, 2017
    Applicant: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE A CADEMY OF SCIENCES
    Inventors: Qiang LIN, Wei LUO, Geng QIN, Huixian ZHANG, Yanhong ZHANG
  • Publication number: 20160368846
    Abstract: The invention discloses a new strepsesquitriol A, a preparation method thereof and an application thereof. Strepsesquitriol A, a structure as shown in Formula (I), is a compound having a new skeleton and strongly inhibiting the formation of LPS-induced TNF? but showing no cytotoxic activity, so it can be used for the preparation of anti-inflammatory drug or act as a precursor of anti-inflammatory drugs, for the treatment of multiple inflammations. Therefore, the invention provides a new candidate compound for the development of anti-inflammatory drugs, and is of great significance for developing Chinese marine drug resources.
    Type: Application
    Filed: December 30, 2013
    Publication date: December 22, 2016
    Applicant: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE A CADEMY OF SCIENCES
    Inventors: Xianwen Yang, Kun Peng, Sumei Li, Gaiyun Zhang, Jie Li, Xiuping Lin, Yonghong Liu
  • Publication number: 20160333687
    Abstract: An in-situ and on-line acoustic measuring system for natural gas flux at the hydrocarbon seeps at a seafloor includes a seepage tent and a flow measuring channel. The flow measuring channel includes a lower bubble breaking channel, an ultrasonic transducer measuring channel and an upper bubble breaking channel. The lower bubble breaking channel communicates with the seepage tent provided with bubble breaking grids. Lower and upper bubble breaking devices, arranged in a bubble rising direction, are respectively mounted in the lower and upper bubble breaking channels. One side of the ultrasonic transducer measuring channel is fixedly connected with an acoustic wave demultiplexer, and the other side is fixedly connected with flat receiving transducers receiving transmitting acoustic waves generated by an acoustic wave branching unit.
    Type: Application
    Filed: February 5, 2015
    Publication date: November 17, 2016
    Applicants: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY CHINESE ACADEMY OF SCIENCES, GUANGDONG UNIVERSITY OF TECHNOLOGY
    Inventors: Pengfei Di, Jianjun Long, Daxin Long, Linying Chen, Dong Feng, Duofu Chen
  • Patent number: 9322040
    Abstract: The invention discloses a Pseudonocardia sp. and a method for preparing Deoxynyboquinone by utilizing the same. Pseudonocardia sp. SCSIO 01299 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011255 on Jul. 18, 2011. The Pseudonocardia sp. SCSIO 01299 can produce antibiotic Deoxynyboquinone, so that the Pseudonocardia sp. SCSIO 01299 can be utilized for preparing Deoxynyboquinone and a new way is provided for producing antibiotic Deoxynyboquinone with anti-tumor activity.
    Type: Grant
    Filed: September 1, 2011
    Date of Patent: April 26, 2016
    Assignee: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Si Zhang, Changsheng Zhang, Xinpeng Tian, Sumei Li, Wenjun Zhang, Haibo Zhang, Guangtao Zhang, Hao Yin, Jianhua Ju
  • Patent number: 9200301
    Abstract: The invention discloses marine Streptomyces sp., a Pyranosesquiterpene compound, as well as a preparation method and uses thereof. Streptomyces sp. SCSIO 01689 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011257 on Jul. 18, 2011. The Streptomyces sp. SCSIO 01689 can produce the Pyranosesquiterpene compound with better anti-Escherichia coli activity and anti-Artemia activity, as well as Cyclo(D)-Pro-(D)-Ile, Cyclo(D)-Pro-(D)-Leu and Cyclo(D)-trans-4-OH-Pro-(D)-Phe with better anti-Vibrio anguillarum activity and anti-Artemia activity, thereby providing a new way for preparing the Cyclo(D)-Pro-(D)-Ile, the Cyclo(D)-Pro-(D)-Leu and the Cyclo(D)-trans-4-OH-Pro-(D)-Phe. The Pyranosesquiterpene compound can be used for preparing anti-Escherichia coli medicaments and anti-Artemia medicaments, as well as preparing condiments as a condiment precursor compound.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: December 1, 2015
    Assignee: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Lijuan Long, Xinpeng Tian, Jie Li, Xiongming Luo, Zhenxiong Qi, Tuan Yin, Hao Yin, Jian Yang
  • Publication number: 20150306025
    Abstract: Provided herein is a bee venom composition with effects of protecting and beautifying lips, comprising cosmetic matrix components for use on lips and bee venom. The bee venom is prepared by using the following method: crude bee venom is dissolved with water, before ultrafiltrated using an ultrafiltration membrane with the molecular weight cutoff 10000 Da, and then the resulting filtrate is freeze-dried to obtain the bee venom.
    Type: Application
    Filed: January 24, 2013
    Publication date: October 29, 2015
    Applicant: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Hua CHEN, Huili SUN, Si ZHANG, Jianyu PAN, Bingna CAI, Xiaoyu SUN
  • Publication number: 20130316408
    Abstract: The invention discloses marine Streptomyces sp., a Pyranosesquiterpene compound, as well as a preparation method and uses thereof. Streptomyces sp. SCSIO 01689 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011257 on Jul. 18, 2011. The Streptomyces sp. SCSIO 01689 can produce the Pyranosesquiterpene compound with better anti-Escherichia coli activity and anti-Artemia activity, as well as Cyclo(D)-Pro-(D)-Ile, Cyclo(D)-Pro-(D)-Leu and Cyclo(D)-trans-4-OH-Pro-(D)-Phe with better anti-Vibrio anguillarum activity and anti-Artemia activity, thereby providing a new way for preparing the Cyclo(D)-Pro-(D)-Ile, the Cyclo(D)-Pro-(D)-Leu and the Cyclo(D)-trans-4-OH-Pro-(D)-Phe. The Pyranosesquiterpene compound can be used for preparing anti-Escherichia coli medicaments and anti-Artemia medicaments, as well as preparing condiments as a condiment precursor compound.
    Type: Application
    Filed: June 18, 2012
    Publication date: November 28, 2013
    Applicant: South China Sea Institute Of Oceanology, Chinese Academy of Sciences
    Inventors: Lijuan Long, Xinpeng Tian, Jie Li, Xiongming Luo, Zhenxiong Qi, Tuan Yin
  • Publication number: 20130230890
    Abstract: The invention discloses a Pseudonocardia sp. and a method for preparing Deoxynyboquinone by utilizing the same. Pseudonocardia sp. SCSIO 01299 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011255 on Jul. 18, 2011. The Pseudonocardia sp. SCSIO 01299 can produce antibiotic Deoxynyboquinone, so that the Pseudonocardia sp. SCSIO 01299 can be utilized for preparing Deoxynyboquinone and a new way is provided for producing antibiotic Deoxynyboquinone with anti-tumor activity.
    Type: Application
    Filed: September 1, 2011
    Publication date: September 5, 2013
    Applicant: South China Sea Institute of Oceanology, Chinese Academy of Sciences
    Inventors: Si Zhang, Changsheng Zhang, Xinpeng Tian, Sumei Li, Wenjun Zhang, Haibo Zhang, Guangtao Zhang, Hao Yin, Jianhua Ju