Patents Assigned to SPIBER INC.
  • Patent number: 11981088
    Abstract: Disclosed is a molded article including a modified fibroin and a water resistance-imparting material. The modified fibroin and the water resistance-imparting material may be covalently bonded.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: May 14, 2024
    Assignee: Spiber Inc.
    Inventors: Kazuki Sakata, Kentaro Takahashi
  • Publication number: 20240083955
    Abstract: The present invention relates to a highly contracted artificial fibroin fiber including a modified fibroin, in which a contraction percentage defined by the following equation exceeds 7%.
    Type: Application
    Filed: October 6, 2023
    Publication date: March 14, 2024
    Applicants: Spiber Inc., Kojima Industries Corporation
    Inventors: Junichi Sugahara, Keisuke Morita, Hiroyuki Nakamura
  • Patent number: 11851684
    Abstract: Disclosed is an expression cassette comprising, in a 5? to 3? direction of a sense strand, a promoter, and a first nucleic acid, a terminator and a second nucleic acid operably linked to the promoter, wherein the first nucleic acid and the second nucleic acid each contain at least one gene.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: December 26, 2023
    Assignee: Spiber Inc.
    Inventor: Masahiro Murakami
  • Publication number: 20230248020
    Abstract: The present invention relates to a meat-like food composition containing: at least one raw material selected from the group consisting of a meat raw material and a meat substitute composition raw material; and a sheet containing a purified protein.
    Type: Application
    Filed: June 8, 2021
    Publication date: August 10, 2023
    Applicant: Spiber Inc.
    Inventors: Yu Chun Chuang, Arin Naidu
  • Publication number: 20230212798
    Abstract: An object of the present invention is to provide a nonwoven fabric that makes it difficult to diffuse liquid in a plane direction and can absorb and transmit liquid in a spot manner, that is, a nonwoven fabric excellent in so-called spot absorbability. The nonwoven fabric according to the present invention is formed by mixing an artificial protein fiber and a hydrophobic synthetic fiber.
    Type: Application
    Filed: May 27, 2021
    Publication date: July 6, 2023
    Applicants: Shinwa Corp., Spiber Inc.
    Inventors: Akira Takaoka, Nozomi Ando, Kyota Fukui, Akihiko Ozeki
  • Patent number: 11692015
    Abstract: The present invention relates to a modified fibroin including a domain sequence represented by Formula 1: [(A)nmotif-REP]m or Formula 2: [(A)nmotif-REP]m?(A)n motif, in which the domain sequence has an amino acid sequence with a reduced content of a glutamine residue equivalent to an amino acid in which one or a plurality of glutamine residues in REP are deleted or substituted with other amino acid residues, as compared with a naturally occurring fibroin.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: July 4, 2023
    Assignees: Spiber Inc., Riken
    Inventors: Keisuke Morita, Yunosuke Abe, Takehisa Maekawa, Koichi Kotaka, Junichi Sugahara, Keiji Numata
  • Publication number: 20230174997
    Abstract: The present invention relates to a method for preparing a plasmid containing DNA that encodes a Type I polyketide synthase (PKS), the method including a step of introducing a DNA construct containing tandem repeats of DNA that encodes a PKS into a Bacillus subtilis competent cell.
    Type: Application
    Filed: May 25, 2021
    Publication date: June 8, 2023
    Applicant: Spiber Inc.
    Inventors: David Lips, Gijs Verkleij
  • Publication number: 20230174956
    Abstract: The present invention relates to a method of preparing a gene cluster construct including a plurality of genes encoding a multi-modular biosynthetic enzyme, the method including (A) a step of preparing a plurality of DNA fragments which are capable of reconstructing the gene cluster construct and have structures that can be ligated to each other and (B) a step of ligating the plurality of DNA fragments prepared in the step (A) to each other by mixing the plurality of DNA fragments in a solution to obtain the gene cluster construct.
    Type: Application
    Filed: May 25, 2021
    Publication date: June 8, 2023
    Applicant: Spiber Inc.
    Inventors: David Lips, Gijs Verkleij
  • Patent number: 11668024
    Abstract: A polar solvent solution of the present invention is a polar solvent solution in which a solute containing a polyamine acid is dissolved in a polar solvent. The solution has a moisture content of less than 5 mass % based on 100 mass % of the solution. A method for producing a polar solvent solution of the present invention includes changing a moisture content of the solution to adjust the viscosity of the solution. Further, another method for producing a polar solvent solution includes reducing a moisture content of the solution to increase the viscosity of the solution. Thus, the present invention provides a polar solvent solution that enables stable spinning and casting without lowering its viscosity when used as dopes for spinning, film, etc., and methods for producing the same.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: June 6, 2023
    Assignee: SPIBER, INC.
    Inventors: Kana Ishida, Hironori Yamamoto, Hiroaki Suzumura, Kazuhide Sekiyama
  • Publication number: 20230128695
    Abstract: An aspect of the present disclosure provides a synthetic polymer containing a first segment containing a polypeptide skeleton and one or a plurality of second segments bonded directly to the first segment, in which the second segment contains a molecular group having a plasticizing function for the polypeptide skeleton.
    Type: Application
    Filed: March 16, 2021
    Publication date: April 27, 2023
    Applicant: Spiber Inc.
    Inventors: Kazuki Sakata, Nao Kitahara, Seiji Shirakawa, Kentaro Takahashi, Leona Muto, Oliver Syed Shafaat, Hideki Kagata
  • Publication number: 20230095432
    Abstract: To provide a meat substitute composition having a texture and sensory properties closer to those of real meat than a meat substitute composition in the related art, the present disclosure provides meat substitute composition containing a polypeptide that satisfies the following (1) or (2): (1) number of amino acid residues is 150 or more, an alanine residue content is 12 to 40%, and a glycine residue content is 11 to 55%; or (2) an amino acid residue content of at least one type selected from the group consisting of serine, threonine, and tyrosine, an alanine residue content, and a glycine residue content account for 56% or more altogether.
    Type: Application
    Filed: January 29, 2021
    Publication date: March 30, 2023
    Applicant: Spiber Inc.
    Inventors: Yu Chun Chuang, Li Jiang, Arin Naidu
  • Publication number: 20230048796
    Abstract: Provided is a fiber for rubber reinforcement that can be produced using a bio-derived raw material and hardly breaks even when compounded with a rubber material. A first fiber for rubber reinforcement uses a protein fiber containing a hydrophobic protein. A second fiber for rubber reinforcement uses a protein fiber having an initial tensile modulus of elasticity of 2.0 GPa or more when wet. These fibers for rubber reinforcement preferably have a coating layer made of a water-based adhesive composition on the surface thereof.
    Type: Application
    Filed: December 17, 2020
    Publication date: February 16, 2023
    Applicants: BRIDGESTONE CORPORATION, Spiber Inc.
    Inventor: Masaaki NAKAMURA
  • Publication number: 20230039765
    Abstract: An object of the present invention is to provide a method capable of producing a protein fiber in which shrinkage at the time of first contact with moisture after production is more reliably suppressed and generation of crimp is also suppressed. A method for producing a protein fiber according to the present invention includes: a pre-shrinking step of shrinking a protein fibril in a relaxed state after drawing and before being wound; a winding step of winding the protein fibril subjected to the pre-shrinking step to obtain a wound product; and a post-shrinking step of shrinking the protein fibril subjected to the winding step in a relaxed state.
    Type: Application
    Filed: September 25, 2020
    Publication date: February 9, 2023
    Applicant: Spiber Inc.
    Inventors: Hideto Ishii, Mizuki Igarashi, Tatsuki Adachi, Yunosuke Abe
  • Publication number: 20220411968
    Abstract: An object of the present invention is to provide an agent for imparting a cool touch feeling property and a water-absorbing and quick-drying property. The agent for imparting a cool touch feeling property and a water-absorbing and quick-drying property contains a modified fibroin as an active ingredient.
    Type: Application
    Filed: September 28, 2020
    Publication date: December 29, 2022
    Applicant: Spiber Inc.
    Inventors: Hiroaki Suzumura, Yui Hirose
  • Publication number: 20220378871
    Abstract: To provide a muscle tissue-regenerating agent containing a fibroin protein. A muscle tissue-regenerating agent containing a modified fibroin protein.
    Type: Application
    Filed: September 30, 2020
    Publication date: December 1, 2022
    Applicants: Spiber Inc., National University Corporation Tokai National Higher Education and Research System
    Inventors: Hiroo Uchida, Hizuru Nagata, Akinari Hinoki, Masataka Fujii, Yun-Hsiang Chang, Satoshi Harada, Takehiro Sato
  • Publication number: 20220332993
    Abstract: An object of the present invention is to provide a protein adhesive containing a protein, a joined body, and a method for producing the same. The protein adhesive of the present invention contains a protein of 50 KDa or less. The joined body of one embodiment is a joined body including a first object, a second object, and an adhesive layer interposed between the first object and the second object, in which the first object and the second object are joined by the adhesive layer, and the adhesive layer is an adhesive layer formed of a protein adhesive containing a protein of 50 KDa or less.
    Type: Application
    Filed: September 30, 2020
    Publication date: October 20, 2022
    Applicant: Spiber Inc.
    Inventor: Yun-Hsiang Chang
  • Publication number: 20220324923
    Abstract: An object of the present invention is to provide a method for advantageously producing a protein molded article which can solve a problem caused by esterification of a hydroxyl group contained in a protein while maintaining a sufficient strength. A method for producing a protein molded article according to the present invention includes a step of bringing a raw material molded article containing a protein in which a hydroxyl group is esterified into contact with an acidic or basic medium in a state of applying a tensile force, thus hydrolyzing an ester group.
    Type: Application
    Filed: September 28, 2020
    Publication date: October 13, 2022
    Applicant: Spiber Inc.
    Inventors: Kentaro Takahashi, Atsushi Ikeda, Hideki Kagata, Yunosuke Abe, Kazuki Sakata
  • Publication number: 20220251739
    Abstract: An object of the present invention is to provide a fabric capable of easily and inexpensively forming a desired three-dimensional shape. The fabric according to the present invention contains an artificial protein fiber that contains a protein, in which the fabric has a surface including: a portion A that shrinks at a predetermined shrinkage rate when being brought into contact with water; and a portion B that has a shrinkage rate lower than that of the portion A when being brought into contact with water.
    Type: Application
    Filed: June 26, 2020
    Publication date: August 11, 2022
    Applicants: Spiber Inc., Yuima Nakazato Co., Ltd.
    Inventors: Yuima Nakazato, Atsushi Ikeda
  • Publication number: 20220251150
    Abstract: An object of the present invention is to provide an artificial fur which has a sufficient moisture-absorbing property and reduces energy required for the manufacture. The artificial fur according to this invention includes an artificial protein fiber.
    Type: Application
    Filed: June 24, 2020
    Publication date: August 11, 2022
    Applicant: Spiber Inc.
    Inventor: Akito Sato
  • Publication number: 20220235099
    Abstract: Provided is a structural protein microbody that functions as a core for forming a protein nanofiber. There is provided a structural protein microbody including a structural protein, in which the structural protein microbody satisfies at least two of the following (i) to (iii): (i) a peak is present within a range of 480 to 500 nm in a fluorescence intensity measurement by thioflavin T staining; (ii) a peak is present in a region where Q is 0.15 or less in a modified Kratky plot of small angle X-ray scattering (SAXS); and (iii) the structural protein microbody is an aggregate of two or more structural protein molecules.
    Type: Application
    Filed: May 28, 2020
    Publication date: July 28, 2022
    Applicant: Spiber Inc.
    Inventors: Hironari Kamikubo, Yugo Hayashi, Takehiro Sato