Patents Assigned to Spiration, Inc.
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Publication number: 20130225997Abstract: Systems, methods, and devices for biopsying tissue, in particular lung nodules, with a flexible needle are described herein. Preferably, the flexible needle is able to articulate or bend so as to provide access to areas previously difficult or impossible to biopsy. Further embodiments provide for steering and navigating the flexible needle to a region to be biopsied.Type: ApplicationFiled: February 26, 2013Publication date: August 29, 2013Applicant: SPIRATION, INC.Inventor: SPIRATION, INC.
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Publication number: 20130225996Abstract: Systems, methods, and devices for biopsying tissue, in particular lung nodules, with a flexible needle are described herein. Preferably, the flexible needle is able to articulate or bend so as to provide access to areas previously difficult or impossible to biopsy. Further embodiments provide for steering and navigating the flexible needle to a region to be biopsied.Type: ApplicationFiled: February 26, 2013Publication date: August 29, 2013Applicant: SPIRATION, INC.Inventor: SPIRATION, INC.
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Publication number: 20130190679Abstract: A method of minimally invasively reducing a volume of a hyper-inflated target section of diseased lung comprising the steps of introducing a bronchoscope into a patient's airway to a position adjacent the target section and equilibrating air within the target section with atmospheric air to at least partially deflate the target lung section; injecting an inflammation-causing substance into the target section to precipitate adhesion of the walls within the target lung section, preventing substantial re-inflation of the target section by occluding an airway upstream of the target section for a period of time, and removing the airway occlusion after the target section has substantially permanently been reduced in volume. The injected substance can be autologous blood or a constituent thereof.Type: ApplicationFiled: December 5, 2012Publication date: July 25, 2013Applicant: SPIRATION, INC.Inventor: Spiration, Inc.
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Patent number: 8454708Abstract: An implantable device for providing one-way flow of air through a lumen in a human lung to reduce the volume of air trapped in a diseased portion of the lung by occluding the lumen to prevent inhalation while permitting expiration out of the diseased portion. The implantable device is deployable in the lumen with a catheter. The device comprises an umbrella-shaped, one-way valve. The valve is collapsible for containment within a catheter and expandable in situ when deployed to occlude the lumen. The valve defines a longitudinal axis and comprises a plurality of metal struts, a resilient membrane, and a central post. The device further comprises an anchor for securing the implantable device within the lumen. The anchor comprises a tapered distal end for penetrating the wall of the lumen, and a planar member positioned to limit advancement of the anchor into the lumen. The implantable device further comprises a mechanism connecting the one-way valve to the anchor.Type: GrantFiled: April 5, 2010Date of Patent: June 4, 2013Assignee: Spiration, Inc.Inventors: James Kutsko, Seung Yi, Clinton Lee Finger
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Patent number: 8444690Abstract: Systems and devices for minimally invasively treating an air leak in a lung comprise the steps of detecting an air leak in a lung; locating an airway in fluid communication with the air leak, introducing a bronchoscope into a patient's airway to a position adjacent the target section and occluding an airway upstream of the air leak for a period of time. The airway occlusion device is preferably removed after the air leak has substantially permanently healed. The occluding device may be a one-way valve. The occluding device may also comprise strut members and anchors that penetrate an airway wall.Type: GrantFiled: January 12, 2011Date of Patent: May 21, 2013Assignee: Spiration, Inc.Inventors: Hugo Xavier Gonzalez, Steven C Springmeyer, William A. Sirokman
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Patent number: 8414655Abstract: An air passageway obstruction device includes a frame structure and a flexible membrane overlying the frame structure. The frame structure is collapsible upon advancement of the device into the air passageway, expandable into a rigid structure upon deploying in the air passageway and recollapsible upon removal from the air passageway. The flexible membrane obstructs inhaled air flow into a lung portion communicating with the air passageway. The device may be removed after deployment in an air passageway by recollapsing the device and pulling the device proximally through a catheter.Type: GrantFiled: July 1, 2010Date of Patent: April 9, 2013Assignee: Spiration, Inc.Inventors: Clifton A. Alferness, Hugo X. Gonzalez, David H. Dillard
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Publication number: 20120289772Abstract: A deployment catheter is described herein that preferably is configured to deliver a medical device such as a valve to a location in a patient such as a patient's airway. Preferably, such a deployment catheter is configured to be used in conjunction with a bronchoscope. In some embodiments, a locking lever is provided to reduce the likelihood of accidental deployment of the device, and which resets conveniently after use to as to permit multiple device deployments.Type: ApplicationFiled: May 13, 2011Publication date: November 15, 2012Applicant: Spiration, Inc.Inventors: Desmond O'Connell, Erik Liljegren, David H. Dillard, Hugo X. Gonzalez
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Publication number: 20120289989Abstract: An intra-bronchial device placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes a support structure, an obstructing member carried by the support structure that reduces ventilation to the lung portion by preventing air from being inhaled into the lung portion, and at least one anchor carried by the support structure that anchors the obstruction device within the air passageway. The anchor may engage the air passageway wall by piercing or friction, include a stop dimensioned for limiting the piercing of the air passageway wall, and may be releasable from the air passageway for removal of the intra-bronchial device. The anchors may be carried by a peripheral portion of the support structure, or by a central portion of the support structure. The obstructing member may be a one-way valve.Type: ApplicationFiled: July 20, 2012Publication date: November 15, 2012Applicant: SPIRATION, INC.Inventors: David H. Dillard, Hugo X. Gonzalez, Seung Yi, Lauri J. DeVore, Mia Park, Dean T. Corcoran, Jenni Rimbaugh, Clifton A. Alferness
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Patent number: 8257381Abstract: An intra-bronchial device placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes a support structure, an obstructing member carried by the support structure that reduces ventilation to the lung portion by preventing air from being inhaled into the lung portion, and at least one anchor carried by the support structure that anchors the obstruction device within the air passageway. The anchor may engage the air passageway wall by piercing or friction, include a stop dimensioned for limiting the piercing of the air passageway wall, and may be releasable from the air passageway for removal of the intra-bronchial device. The anchors may be carried by a peripheral portion of the support structure, or by a central portion of the support structure. The obstructing member may be a one-way valve.Type: GrantFiled: December 15, 2010Date of Patent: September 4, 2012Assignee: Spiration, Inc.Inventors: David H. Dillard, Hugo X. Gonzalez, Seung Yi, Lauri J. DeVore, Mia Park, Dean T. Corcoran, Jenni Rimbaugh, Clifton A. Alferness
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Publication number: 20120209308Abstract: Embodiments disclosed herein relate to devices implantable into a human lung, for example to reduce the volume of air trapped in a diseased portion of the lung to prevent inhalation while permitting expiration out of the diseased portion. In some embodiments, the device comprises a distal portion with an anchor system that may anchor the device into tissue of an air passageway wall, and the distal portion may be connected to a proximal portion via a flexible portion that permits the distal portion to articulate substantially with respect to the proximal portion, such that the distal portion and the proximal portion may be non-collinear along a longitudinal axis of the distal portion. This may facilitate implantation of the device into a non-linear air passageway.Type: ApplicationFiled: April 26, 2012Publication date: August 16, 2012Applicant: SPIRATION, INC.Inventors: James Kutsko, Seung Yi, Clinton Lee Finger
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Publication number: 20120165856Abstract: An intra-bronchial device may be placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member that prevents air from being inhaled into the lung portion, and an anchor that anchors the obstruction device within the air passageway. The anchor may piercingly engage the air passageway wall. The anchor may be releasable from the air passageway for removal of the obstructing member. The anchor may be releasable by collapsing a portion of the obstructing member, or by drawing the obstructing member toward the larynx. The obstructing member may be a one-way valve.Type: ApplicationFiled: March 8, 2012Publication date: June 28, 2012Applicant: SPIRATION, INC.Inventor: Clifton A. Alferness
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Patent number: 8177805Abstract: An intra-bronchial device may be placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member that prevents air from being inhaled into the lung portion, and an anchor that anchors the obstruction device within the air passageway. The anchor may piercingly engage the air passageway wall. The anchor may be releasable from the air passageway for removal of the obstructing member. The anchor may be releasable by collapsing a portion of the obstructing member, or by drawing the obstructing member toward the larynx. The obstructing member may be a one-way valve.Type: GrantFiled: August 4, 2011Date of Patent: May 15, 2012Assignee: Spiration, Inc.Inventor: Clifton A. Alferness
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Publication number: 20120101428Abstract: A method of minimally invasively reducing a volume of a hyper-inflated target section of diseased lung comprising the steps of introducing a bronchoscope into a patient's airway to a position adjacent the target section and equilibrating air within the target section with atmospheric air to at least partially deflate the target lung section; injecting an inflammation-causing substance into the target section to precipitate adhesion of the walls within the target lung section, preventing substantial re-inflation of the target section by occluding an airway upstream of the target section for a period of time, and removing the airway occlusion after the target section has substantially permanently been reduced in volume. The injected substance can be autologous blood or a constituent thereof.Type: ApplicationFiled: November 1, 2011Publication date: April 26, 2012Applicant: SPIRATION, INC.Inventor: Steven C. Springmeyer
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Publication number: 20120073126Abstract: A valve loading system is provided that uses a valve loader to transfer a valve or other medical device from a storage cartridge into a deployment catheter. The valve or other medical device can be implanted or positioned within a patient using the catheter after the valve or other medical device has been compressed and loaded into the catheter using the valve loader. The process then can be repeated by using the valve loading system to load or introduce another valve or other medical device into the catheter.Type: ApplicationFiled: December 6, 2011Publication date: March 29, 2012Applicant: SPIRATION, INC.Inventors: Martin Neal Adams, James Mark Kutsko, Desmond O'Connell
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Patent number: 8136230Abstract: A valve loading system is provided that uses a valve loader to transfer a valve or other medical device from a storage cartridge into a deployment catheter. The valve or other medical device can be implanted or positioned within a patient using the catheter after the valve or other medical device has been compressed and loaded into the catheter using the valve loader. The process then can be repeated by using the valve loading system to load or introduce another valve or other medical device into the catheter.Type: GrantFiled: October 10, 2008Date of Patent: March 20, 2012Assignee: Spiration, Inc.Inventors: Martin Neal Adams, James Mark Kutsko, Desmond O'Connell
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Publication number: 20120016376Abstract: A valve loading system is provided that uses a valve loader to transfer a valve or other medical device from a storage cartridge into a deployment catheter. The valve or other medical device can be implanted or positioned within a patient using the catheter after the valve or other medical device has been compressed and loaded into the catheter using the valve loader. The process then can be repeated by using the valve loading system to load or introduce another valve or other medical device into the catheter.Type: ApplicationFiled: September 23, 2011Publication date: January 19, 2012Applicant: SPIRATION, INC.Inventors: Martin Neal Adams, James Mark Kutsko, Desmond O'Connell
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Patent number: 8079368Abstract: A method of minimally invasively reducing a volume of a hyper-inflated target section of diseased lung comprising the steps of introducing a bronchoscope into a patient's airway to a position adjacent the target section and equilibrating air within the target section with atmospheric air to at least partially deflate the target lung section; injecting an inflammation-causing substance into the target section to precipitate adhesion of the walls within the target lung section, preventing substantial re-inflation of the target section by occluding an airway upstream of the target section for a period of time, and removing the airway occlusion after the target section has substantially permanently been reduced in volume. The injected substance can be autologous blood or a constituent thereof.Type: GrantFiled: March 10, 2010Date of Patent: December 20, 2011Assignee: Spiration, Inc.Inventor: Steven C. Springmeyer
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Publication number: 20110283998Abstract: An intra-bronchial device may be placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member that prevents air from being inhaled into the lung portion, and an anchor that anchors the obstruction device within the air passageway. The anchor may piercingly engage the air passageway wall. The anchor may be releasable from the air passageway for removal of the obstructing member. The anchor may be releasable by collapsing a portion of the obstructing member, or by drawing the obstructing member toward the larynx. The obstructing member may be a one-way valve.Type: ApplicationFiled: August 4, 2011Publication date: November 24, 2011Applicant: SPIRATION, INC.Inventor: CLIFTON A. ALFERNESS
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Patent number: 8043301Abstract: A valve loading system is provided that uses a valve loader to transfer a valve or other medical device from a storage cartridge into a deployment catheter. The valve or other medical device can be implanted or positioned within a patient using the catheter after the valve or other medical device has been compressed and loaded into the catheter using the valve loader. The process then can be repeated by using the valve loading system to load or introduce another valve or other medical device into the catheter.Type: GrantFiled: April 10, 2009Date of Patent: October 25, 2011Assignee: Spiration, Inc.Inventors: Martin Neal Adams, James Mark Kutsko, Desmond O'Connell
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Patent number: 8021385Abstract: A method for treating a lung using an intra-bronchial device may be placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The method includes using an obstructing member that prevents air from being inhaled into the lung portion, and an anchor that anchors the obstruction device within the air passageway. The anchor may piercingly engage the air passageway wall. The anchor may be releasable from the air passageway for removal of the obstructing member. The anchor may be releasable by collapsing a portion of the obstructing member, or by drawing the obstructing member toward the larynx. The obstructing member may be a one-way valve.Type: GrantFiled: July 19, 2007Date of Patent: September 20, 2011Assignee: Spiration, Inc.Inventor: Clifton A. Alferness