Abstract: An article of footwear includes a shoe with a sole and upper, a toy element, and a snap attachment assembly consisting of cooperating male and female components. The female component is attached to the shoe. The cooperating male component is attached to the ornamental article, which is thus removably assembled with the shoe by cooperative, snap engagement of the female and cooperating male components of the snap attachment assembly. In preferred embodiments, one or several ornamental articles are interchangeably displayed on shoes and on fashion display accessories, e.g., bracelets, barrettes, chains and pendants.
Abstract: Means for diagnosing t(8;21) translocation type acute myeloid leukemia with high sensitivity by a simple operation are disclosed. The present invention provided AML1-MTG8 fused DNA having the nucleotide sequence shown in SEQ ID No. 1 and DNA fragments thereof containing the fused site. The present invention provided AML1-MTG8 fused polypeptide having the amino acid sequence shown in SEQ ID No. 2, and fragments thereof containing the fused site. The present invention provided AML1-MTG8 fused mRNA having the same nucleotide sequence as shown in SEQ ID No. 1 except that thymine is replaced with uracil, and fragments thereof. The present invention provided a probe which is said DNA fragment that is labelled. The present invention provided a method for detecting said fused DNA by using said probe.
Type:
Grant
Filed:
August 15, 1994
Date of Patent:
December 3, 1996
Assignee:
SRL, Inc.
Inventors:
Misao Ohki, Kimiko Kikuchi, Hiroyuki Miyoshi, Tomoko Kozu