Abstract: Embodiments of the present invention provide an electromagnet alignment system for AM or 3D printing technology providing improved in-situ alignment of the magnetic particulate material as it is dispensed during deposition to form a 3D shape. In-situ alignment of the magnetic particulate material can be controlled to be unidirectional or multi-directional.
Type:
Grant
Filed:
April 15, 2021
Date of Patent:
August 27, 2024
Assignees:
Iowa State University Research Foundation, Inc., UT-Battelle, LLC
Inventors:
Cajetan Ikenna Niebedim, Abhishek Sarkar, Matthew J. Kramer, Thomas Lograsso, Mark Christopher Haase, Somashekara Adinarayanappa, Mariappan Parans Paranthaman
Abstract: A well plate for measuring an analyte in a sample is disclosed. The well plate includes at least a first, a second, and a third electrode. The first electrode has a higher sensitivity to a first analyte than the second and third electrodes. The second electrode has a higher sensitivity to a second analyte than the first and third electrodes.
Type:
Grant
Filed:
April 11, 2020
Date of Patent:
August 27, 2024
Assignee:
Colorado State University Research Foundation
Inventors:
Thomas W. Chen, Daniel S. Ball, Caleb R. Begly
Abstract: The present disclosure provides compositions and methods for decreasing permissiveness to infection by PRRSV. The methods involve inserting peptides or oligopeptides into the CD163 SRCR domain 5 to disrupt the protein structure and thereby prevent PRRSV infection. The deletion of the exon 13 region of PSTII eliminates infection. The replacement of cysteine residues with alanines in SRCR5 as a means to disrupt disulfide bond formation. The final method is the deletion of, or amino acid substitution within the SRCR4-5 interdomain region.
Type:
Grant
Filed:
October 16, 2018
Date of Patent:
August 13, 2024
Assignee:
Kansas State University Research Foundation
Abstract: Provided herein are binding polypeptides, such as binding peptides and antibodies, against a SARS CoV-2. The binding polypeptides relate to or are based on bovine antibodies, particularly those containing an ultralong CDR3. Also provided herein are methods of treating a virus infection, such as a coronavirus infection, by delivering to a subject in need a provided binding polypeptide.
Type:
Application
Filed:
May 11, 2022
Publication date:
August 8, 2024
Applicants:
Applied Biomedical Science Institute, Kansas State University Research Foundation
Abstract: A system for reducing total dissolved solids in wastewater can include a vertical reactor that can include a flexible sheet material, where the flexible sheet material can be configured to facilitate the growth and attachment of an algal biofilm. The vertical reactor can include a shaft, where the shaft can be associated with and can support the flexible sheet material, and a drive motor, where the drive motor can be coupled with the shaft such that the flexible sheet material can be selectively actuated. The system can include a fluid reservoir containing a portion of wastewater through which the flexible sheet material is configured to pass as well as a stressor operably configured to stimulate the algae to produce an extracellular polymeric substance. A method of reducing total dissolved solids in wastewater includes moving an algal biofilm through the wastewater and moving the algal biofilm through a gas.
Type:
Grant
Filed:
May 18, 2023
Date of Patent:
August 6, 2024
Assignees:
Iowa State University Research Foundation, Inc., Metropolitan Water Reclamation District of Greater Chicago
Inventors:
Zhiyou Wen, Juan Peng, Martin A. Gross, Kuldip Kumar, Thomas Kunetz
Abstract: A portable sampler, the sampler including a sampler assembly having a housing that includes a receiver defined therein for interchangeably receiving a number of removable inlet assemblies, the removable inlet assemblies including a respirable inlet assembly and a thoracic inlet assembly. The respirable inlet assembly includes a hybrid cyclone assembly, the hybrid cyclone assembly including an impaction stage and a cyclone in series. The thoracic inlet assembly includes an inlet slot configured to function as a size-selective inlet. Another thoracic inlet assembly includes a housing having a number of openings configured to receive a sample airflow; an inlet insert through which an inlet aperture is defined; a prequalification chamber defined between a lower surface of the housing and an upper surface of the inlet insert; and a protrusion extending downward from the lower surface of the housing into the inlet aperture of the inlet insert to from an inlet slot.
Type:
Grant
Filed:
December 18, 2020
Date of Patent:
August 6, 2024
Assignees:
Colorado State University Research Foundation, Access Sensor Technologies LLC
Inventors:
David Leith, John Volckens, Christian L'Orange, Daniel D. Miller-Lionberg
Abstract: In this disclosure, a method or kit for using the method of extracting, concentrating, and detecting microbes from a sample is disclosed. The method disclosed herein use transition or rare earth metal-based magnetic ionic liquids (MILs) to extract viable microbes from a sample and to detect them via an amplification-based method and/or a non-amplification-based methods. The method and kit can be used in-field and on-site for detection of viable microbes in a sample within about an hour, without using any powered heat source or powered tool.
Type:
Grant
Filed:
February 17, 2020
Date of Patent:
August 6, 2024
Assignee:
Iowa State University Research Foundation, Inc.
Inventors:
Jared L. Anderson, Byron F. Brehm-Stecher, Kevin D. Clark, Stephanie A. Hice
Abstract: Methods of hydromethylation of alkenes and ketones, including methods that use Tebbe's reagent. The methods may include contacting Cp2Ti(?-Cl)(?-CH2)AlMe2 and an alkene or a ketone to produce an intermediate product that may include a titanacyclobutane. The intermediate product may be contacted with an acid to produce a methylated product.
Type:
Grant
Filed:
July 26, 2021
Date of Patent:
July 30, 2024
Assignee:
The Florida State University Research Foundation, Inc.
Abstract: Systems and methods are provided for determining properties of seed cotton based on measurements from a near-infrared (NIR) sensor. The determined properties are indicative of a quality of the seed cotton. The NIR sensor is mounted on harvesting equipment to acquire quality data during harvesting. The quality data may be mapped to field location and/or forwarded on in preparation of further processing.
Type:
Application
Filed:
July 27, 2022
Publication date:
July 25, 2024
Applicants:
Deere & Company, Iowa State University Research Foundation
Inventors:
Jeffrey S. WIGDAHL, Jeffrey C. ASKEY, John P. JUST
Abstract: A meta-material is disclosed that includes a first layer composed of graphene, and one or more additional layers, each composed of glassy carbon or graphene. A method of producing an engineered material includes depositing a graphene precursor on a substrate, pyrolyzing the graphene precursor to allow the formation of graphene, depositing a glassy carbon precursor the graphene, pyrolyzing to allow the formation of glassy carbon from the glassy carbon precursor, depositing a graphene precursor on the glassy carbon, and pyrolyzing the graphene precursor to allow the formation of graphene.
Type:
Grant
Filed:
October 25, 2022
Date of Patent:
July 23, 2024
Assignee:
San Diego State University Research Foundation
Inventors:
Samuel K. Kassegne, Elisa Castagnola, Surabhi Nimbalkar
Abstract: Method of increasing protein content in a eukaryotic cell comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site; method of producing a plant with increased protein content comprising crossing and selecting for increased protein content; method of increasing resistance to a pathogen or a pest in a plant cell or plant comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site, alone or in further combination with expressing QQS in the plant cell or plant; method for producing a plant with increased resistance to a pathogen or a pest comprising crossing and selecting for increased resistance to the pathogen or the pest; a cell, collection of cells, tissue, organ, or organism, such as a plant, in which the NF-YC4 gene comprises a promoter comprising a transcriptional repressor binding site that has been modified so that the transcriptional repressor cannot prevent transcription of the NF-YC4; plants and hybrids thereof; and seeds.
Type:
Grant
Filed:
November 21, 2022
Date of Patent:
July 16, 2024
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: Methods of passivating surfaces, composite materials, and electronic devices including the composite materials. The composite materials can include a passivated film, such as a metal halide perovskite passivated with an organic dye. The electronic devices may include solar cells.
Type:
Grant
Filed:
March 2, 2022
Date of Patent:
July 16, 2024
Assignee:
The Florida State University Research Foundation, Inc.
Abstract: Compositions and methods of making a culture medium from a polymeric material are described herein. The method can include (a) depolymerizing and/or dispersing the polymeric material to obtain a depolymerized and/or dispersed residue, and (b) combining the depolymerized and/or dispersed residue with one or more adjuvants to form a culture medium. In some embodiments, the polymeric material can be a plastic article, such as a waste carpet material. Culture media prepared from the compositions and methods are also described. The culture media are suitable for culturing microorganisms including bacterium, algae, and fungus. The microorganisms can be used to produce a bioproduct such as a biopolymer, an enzyme, or a cellular metabolite.
Type:
Grant
Filed:
November 2, 2020
Date of Patent:
July 16, 2024
Assignee:
Georgia State University Research Foundation, Inc.
Abstract: Systems and methods for a virtually coupled modular transportation system. A first module and a second module, in each for transporting a payload, comprise non-physically coupled vehicle sections. In an embodiment, a controller determines a target orientation between modules. In another embodiment, at least one position detection device determines an actual orientation between modules. A motor in at least one module may receive signals from the controller to position the modules in the target orientation. A plurality of wheels on each module may receive an independent amount of torque to position the modules. In another embodiment, at least one module comprises a rechargeable electric motor.
Type:
Grant
Filed:
August 16, 2017
Date of Patent:
July 16, 2024
Assignee:
Kennesaw State University Research and Service Foundation, Inc.
Inventors:
Billy M. Diong, Ying Wang, Jidong J. Yang
Abstract: The disclosure relates to a composition comprising amphiphilic Janus particles and a waterborne binder, wherein the particles are self-stratified, and methods of making and using the same. The disclosure also relates to the synthesis of amphiphilic Janus particles.
Type:
Grant
Filed:
January 4, 2023
Date of Patent:
July 2, 2024
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: In some embodiments, an apparatus includes a volatile memory, a non-volatile memory, a first processor coupled to the non-volatile memory and configured to receive a data set associated with an object and user information associated with a spatial position of a user in a multi-user virtual (IMVR) environment, and a second processor coupled to the volatile memory, the second processor configured to render an instance of the portion of the object in the IMVR environment from a perspective of the user based on the spatial position of the user. The first processor is configured to generate a look-up table (LUT) based on a set of inputs received from a user. The second processor is configured to render, based on the LUT and information related to a manipulation by a user, an updated instance of the portion of the object that manifests an effect of the manipulation in the IMVR environment.
Type:
Grant
Filed:
July 15, 2022
Date of Patent:
July 2, 2024
Assignee:
Colorado State University Research Foundation
Inventors:
Tod Robert Clapp, Brendan Garbe, Chad Eitel
Abstract: A novel microwave ablation applicator includes a flexible tubular shaft and a partially encapsulated antenna. The applicator is adapted to be used with an endoscope in order to access remote targets deep within an organ of a patient. Microwave power is emitted from the antenna in a desired radiation pattern by circulating an attenuating liquid through the shaft and across a portion of the antenna. Microwave ablation systems and methods are described.
Type:
Grant
Filed:
January 26, 2018
Date of Patent:
July 2, 2024
Assignees:
Broncus Medical Inc., Kansas State University Research
Foundation
Inventors:
Austin Pfannenstiel, Thomas M Keast, Henky Wibowo, Punit Prakash
Abstract: A method for predicting remaining useful life for industrial equipment and associated sensor modules are provided. The method includes monitoring machine sensor data for the industrial equipment in an industrial environment using at least one sensor and applying a two-tier model implemented by a computing device by executing a set of instructions from a non-transitory machine readable memory using a processor of the computing device. The two-tier model receives as input sensor data comprising the machine sensor data and applies physics of failure of the industrial equipment to determine a prediction for remaining useful life for the industrial equipment, uncertainty in the prediction for the remaining useful life for the industrial equipment, and an explanation to the prediction for the remaining useful life for the industrial equipment.
Type:
Application
Filed:
December 14, 2023
Publication date:
June 27, 2024
Applicants:
Iowa State University Research Foundation, Inc., Percev LLC
Inventors:
Venkat Pavan Nemani, Chao Hu, Hao Lu, Andrew T. Zimmerman
Abstract: A coat protein of Junonia coenia densovirus (JcDNV) is used to deliver attached peptide insect toxin across the gut epithelium of a fall armyworm, Spodoptera frugiperda. A fusion protein comprising VP4 attached to an insect toxin via a peptide linker is developed. A composition comprising a JcDNV coat protein attached to an insect toxin via a peptide linker can be used for insect pest control.
Type:
Grant
Filed:
September 9, 2021
Date of Patent:
June 25, 2024
Assignees:
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED, Iowa State University Research Foundation, Inc.