Patents Assigned to State University
  • Biosynthesis of paclitaxel intermediate
    Patent number: 9732365
    Abstract: The invention relates to methods of making compounds useful for production of paclitaxel and analogs or derivatives thereof.
    Type: Grant
    Filed: June 18, 2012
    Date of Patent: August 15, 2017
    Assignee: Board of Trustees of Michigan State University
    Inventor: Kevin Walker
  • Compounds and methods for activating the apoptotic arm of the unfolded protein response
    Patent number: 9732067
    Abstract: N-substituted sulfonylphenyl-5-mitrofuranyl-2-carboxamide derived compounds, which selectively activate the apoptotic, but not the adaptive arm, of the Unfolded Protein Response are provided as is their use in the treatment of diseases such as diabetes, Alzheimer's, Parkinson's, hemophilia, lysosomal storage diseases and cancer.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: August 15, 2017
    Assignees: University of Kansas, Sanford-Burnham Medical Research Institute, The Regents of the University of Michigan, Wayne State University
    Inventors: Jennifer E. Golden, Jeffrey Aube, Daniel P. Flaherty, Andrew M. Fribley, Randal J. Kaufman, Thomas D. Y. Chung, Anthony B. Pinkerton, Michael Pablo Hedrick
  • Genomic features associated with epigenetic control regions and transgenerational inheritance of epimutations
    Patent number: 9734283
    Abstract: CpG densities and sequence motifs that are characteristic of regions of DNA associated with epimutations and control of epimutations are provided. Such regions include, within approximately 400 (or fewer) base pairs, at least one, usually two, and preferably all three of the following features: i) a CpG density of 15% or less; ii) the presence of the sequence motif ATTTGTTTTTTCTTTTnT (SEQ ID NO: 1) where n is A, T, C or G, and statistically relevant variants thereof; and iii) the presence of the sequence motif GGGGGnGGGG (SEQ ID NO: 2), where n is A, T, C or G, and statistically relevant variants thereof.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: August 15, 2017
    Assignee: Washington State University
    Inventors: Michael K. Skinner, Carlos M. Guerrero-Bosagna
  • Cloaking with footprints to provide location privacy protection in location-based services
    Patent number: 9736685
    Abstract: A method for using a location-based service while preserving anonymity includes receiving a location associated with a mobile node, receiving an anonymity level associated with the mobile node, computing a region containing the location of the mobile node and a number of footprints based on the anonymity level, wherein each of the footprints from a different user, and providing the region to a location-based service to thereby preserve anonymity of the mobile node. A method also allow a mobile device or its user to specify the anonymity level by selecting a public region consistent with a user's feelings towards desired privacy.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: August 15, 2017
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Ying Cai, Ge Xu
  • USE OF NITRITE SALTS IN TREATING TISSUE DAMAGE
    Publication number: 20170224725
    Abstract: A method of treating neuropathy in a subject, the method comprising identifying a subject who has neuropathy; and administering to the subject a pharmaceutical composition comprising one of inorganic nitrite and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 23, 2017
    Publication date: August 10, 2017
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Christopher KEVIL
  • LIGHT ENDOSCOPE SYSTEM FOR IMAGING, LIGHT DELIVERY, AND THERAPY RESPONSE MONITORING
    Publication number: 20170224205
    Abstract: An endoscopic imaging system is disclosed that includes an endoscope having a first channel and a second channel, a high-power, multi-wavelength LED array, a digital micro-mirror device that receives light directed from the high-power, multi-wavelength LED array and generates spatial frequency patterns, and dichroic mirror that separates reflectance and fluorescence images.
    Type: Application
    Filed: February 6, 2017
    Publication date: August 10, 2017
    Applicant: Wright State University
    Inventors: Ulas Sunar, Dan Rohrbach, Jeremy Kress
  • Cardiac defibrillation with vagus nerve stimulation
    Patent number: 9724516
    Abstract: A method and system for treating cardiac arrhythmias which includes inserting one or more electrodes into a patient's neck, and connecting the electrodes to the vagus nerve in the patient's neck. A cardiac monitoring device detects a cardiac arrhythmia. A controller connected to an electrical power source provides electrical power to the electrodes to apply electrical stimulation to the vagus nerve when a cardiac arrhythmia is detected.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: August 8, 2017
    Assignee: The Research Foundation for The State University of New York
    Inventors: Mark Stewart, Isaac Naggar, Jason Lazar
  • Error resilient pipeline
    Patent number: 9727342
    Abstract: For an error resilient pipeline, a Dynamically Adaptable Resilient Pipeline (DARP) controller determines a minimum error pipeline stage of a processor instruction pipeline with a minimum number of errors. In addition, the DARP controller determines a maximum error pipeline stage of the instruction pipeline with a maximum number of errors. The DARP controller increases a clock frequency for the instruction pipeline if the minimum number of errors of the minimum error pipeline stage is zero and the maximum number of errors of the maximum error pipeline stage does not exceed an error threshold. In addition, the DARP controller decreases the clock frequency if the minimum number of errors exceeds an error constant.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: August 8, 2017
    Assignee: Utah State University
    Inventors: Koushik Chakraborty, Sanghamitra Roy, Hu Chen
  • Nanocrystalline cellulose materials and methods for their preparation
    Patent number: 9724213
    Abstract: Disclosed herein are methods for producing nanocrystalline cellulose and oxidized nanocrystalline cellulose from biomass. Also disclosed are methods for forming materials, and the materials formed from a fibrin matrix that incorporates the nanocrystalline cellulose and/or the oxidized nanocrystalline cellulose.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: August 8, 2017
    Assignee: Washington State University
    Inventors: Xiao Zhang, Elvie Escorrow Brown
  • Apparatus and method for optimal phase balancing using dynamic programming with spatial consideration
    Patent number: 9728971
    Abstract: Provided are an apparatus and method for load-balancing of a three-phase electric power distribution system having a multi-phase feeder, including obtaining topology information of the feeder identifying supply points for customer loads and feeder sections between the supply points, obtaining customer information that includes peak customer load at each of the points between each of the feeder sections, performing a phase balancing analysis, and recommending phase assignment at the customer load supply points.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: August 8, 2017
    Assignee: The Research Foundation for The State University of New York
    Inventors: Thomas G. Robertazzi, Steven Skiena, Kai Wang
  • Shock mitigating materials and methods utilizing spiral shaped elements
    Patent number: 9726249
    Abstract: Various embodiments of a spiral shaped element and embedded wavy materials are disclosed for use in a shock mitigating material to dissipate the energy associated with the impact of an object. The shock mitigating material can be used in helmets, bumpers, bullet proof vests, military armor, and other applications. One embodiment, among others, is a shock mitigating material having a plurality of spiral shaped elements, each having a circular cross section, and each being tapered from a large outside end to a small inside end but also having an embedded wavy material that can induce shear waves to mitigate the shock pressure and impulse.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: August 8, 2017
    Assignee: Mississippi State University
    Inventor: Mark F. Horstemeyer
  • Methods and systems for prediction of fill factor in heterojunction solar cells through lifetime spectroscopy
    Patent number: 9726710
    Abstract: Methods and systems for prediction of fill factor in heterojunction solar cells through lifetime spectroscopy are provided. In accordance with some embodiments, methods for categorizing fill factor in a solar cell are provided, the methods comprising: determining lifetime values of the solar cell at different minority carrier concentrations; determining a lifetime curve shape for the solar cell based on the determined lifetime values; and categorizing the fill factor of the solar cell based on the determined lifetime curve shape using a hardware processor.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: August 8, 2017
    Assignee: Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University
    Inventors: Kunal Ghosh, Stuart Bowden
  • Prodrugs of riluzole and their method of use
    Patent number: 9725427
    Abstract: Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 8, 2017
    Assignees: Biohaven Pharmaceutical Holding Company Limited, Rutgers, The State University of New Jersey
    Inventors: Garry R. Smith, Allen B. Reitz, Mark McDonnell, Suzie Chen, Matthew D. Vera, Benjamin E. Blass, Jeffery C. Pelletier, Venkata N. Velvadapu, Jay E. Wrobel
  • Methods of modulating ubiquitin ligase activity
    Patent number: 9725708
    Abstract: Methods are provided for modulating the activity of multimeric ubiquitin-protein E3 ligases including, but not limited to, E6AP ligase activities. The methods reduce the level of oligomer formation such as homotrimeric E6AP ligase to reduce the enzyme activity. Alternatively, agents are provided that can promote the association of the ligase monomers, thereby increasing the ligase activity. Accordingly, novel therapeutic strategies are provided that are useful for the treatment of pathologies resulting from mutations in the genes encoding the ligases and which adversely increase or decrease a ubiquitination reaction.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: August 8, 2017
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Arthur L. Haas, Virginia P. Ronchi
  • Modified hydrophobic sponges
    Patent number: 9724669
    Abstract: Articles are provided for absorbing fluids. In embodiments, the articles of the present disclosure are modified to make them hydrophobic, thereby decreasing their affinity for water and similar liquids, while increasing their affinity for other hydrophobic materials, including oil. After use, the articles, in embodiments sponges, may have their absorbed materials removed therefrom, and the articles may then be re-used to absorb additional materials.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: August 8, 2017
    Assignee: The Research Foundation for the State University of New York
    Inventors: Benjamin Chu, Benjamin S. Hsiao, Zhe Wang
  • Imidazole derivatives useful for controlling microbial growth
    Patent number: 9723837
    Abstract: Disclosure is provided for 1,4,5-substituted amino imidazole compounds useful to control microbial growth, compositions including these compounds, devices including these compounds, and methods of using the same.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: August 8, 2017
    Assignee: North Carolina State University
    Inventors: Christian Melander, Zhaoming Su, Lingling Peng
  • Methods to treat inflammation of the lung
    Patent number: 9724384
    Abstract: The present invention provides pharmaceutical compositions comprising leukotoxin for the treatment of lung inflammation.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: August 8, 2017
    Assignees: Rutgers, the State University of New Jersey, Actinobac Biomed, Inc.
    Inventors: Scott Kachlany, Benjamin Belinka
  • Self-referencing optical measurement for breast cancer detection
    Patent number: 9724489
    Abstract: Optical data is obtained from a pair of breasts, employing a simultaneous bilateral referencing protocol, and is subsequently analyzed employing a self-referencing data analysis method. Optical measurements can be performed on both breasts simultaneously under various protocols, including resting-state measures and evoked responses. Sensing hardware and data collection protocols are economical and can be implemented without patient discomfort. The natural variance inherently associated with optical measures of the breast is reduced by: imposition of substantially symmetric boundary conditions; collection of simultaneous bilateral dynamic measures; referencing measurement data of one breast to measurement data from another.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: August 8, 2017
    Assignee: The Research Foundation for The State University of New York
    Inventors: Randall L. Barbour, Rabah M. Al Abdi
  • Energy storage device including a redox-enhanced electrolyte
    Patent number: 9728344
    Abstract: An electrical double layer capacitor (EDLC) energy storage device is provided that includes at least two electrodes and a redox-enhanced electrolyte including two redox couples such that there is a different one of the redox couples for each of the electrodes. When charged, the charge is stored in Faradaic reactions with the at least two redox couples in the electrolyte and in a double-layer capacitance of a porous carbon material that comprises at least one of the electrodes, and a self-discharge of the energy storage device is mitigated by at least one of electrostatic attraction, adsorption, physisorption, and chemisorption of a redox couple onto the porous carbon material.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: August 8, 2017
    Assignees: Oregon State University, The Regents of the University of California, University of Oregon
    Inventors: Galen Stucky, Brian Evanko, Nicholas Parker, David Vonlanthen, David Auston, Shannon Boettcher, Sang-Eun Chun, Xiulei Ji, Bao Wang, Xingfeng Wang, Raghu Subash Chandrabose
  • Recovering heavy rare earth metals from magnet scrap
    Patent number: 9725788
    Abstract: A method of treating rare earth metal-bearing permanent magnet scrap, waste or other material in a manner to recover the heavy rare earth metal content separately from the light rare earth metal content. The heavy rare earth metal content can be recovered either as a heavy rare earth metal-enriched iron based alloy or as a heavy rare earth metal based alloy.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: August 8, 2017
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Ryan T. Ott, Ralph W. McCallum, Lawrence L. Jones