Abstract: A computer implemented method for guiding an under-actuated marine surface vessel in tracking a desired trajectory comprises expressing a predetermined vessel trajectory as a set of straight line segments, determining a desired current line segment, and determining the vessel's current position. A cross-track error and the derivative of the cross-track error are then determined. Next, a radius R of the line-of-sight (LOS) circle using a newly introduced exponential function is determined. Intersection points M and N between the LOS circle and the current desired line segment are determined. A desired heading angle is determined as the angle between the line of sight and a predetermined fixed reference line. A drift detection algorithm is built into the proposed guidance scheme to detect situations whereby the ship moves parallel to its desired trajectory for an extended period of time without being able to correct for the cross track error.

Abstract: A hybrid magnesium cement composition formed of an A-side and a B-side. The A-side having an A1-component including a light-burn grade magnesium-containing material, and an A2-component including a non-metallic oxide salt. A B-side having a metal silicate polymer is included.

Abstract: For mapping a sustainable, differentially reliable architecture for dark silicon, a calculation module calculates an expected energy efficiency for a prior mapping of process threads for a plurality of cores. The calculation module further calculates a workload acceptance capacity (WAC) from degradation rates for the plurality of cores. A map module maps the process threads to the plurality of cores based on at least one of the expected energy efficiency and the WAC to satisfy a mapping policy. A specified number of the plurality of cores is not powered.

Abstract: The present invention provides methods and compositions for inhibiting calcium permeable cation conductance of red blood cells from individuals afflicted with sickle cell anemia. The method comprises exposing the cells to the peptide GsMTx4 and/or variants thereof.

Abstract: A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of determining efficacy of a pharmaceutical for treating a disease or staging disease by administering a pharmaceutical to a sample containing markers for a disease, detecting the amount of at least one marker of the disease in the sample, and analyzing the amount of the marker in the sample, whereby the amount of marker correlates to pharmaceutical efficacy or disease stage. Markers for gynecological disease. An immuno-imaging agent comprising labeled antibodies, whereby the labeled antibodies are isolated and reactive to proteins overexpressed in vivo. Informatics software for analyzing the arrays, the software including analyzing means for analyzing the arrays.

Abstract: The present disclosure concerns embodiments of a microfluidic transfer device. The device mitigates risk of cross contamination between working fluids and is amenable to high-volume, low-cost manufacturing techniques. The device may be configured for mass transfer, heat transfer, or both. For instance, certain disclosed embodiments incorporate semi-permeable membranes to transfer target substances from one fluid to another. Moreover, the device may incorporate both heat and mass transfer components.

Abstract: An inventive system and method for monitoring radiation dose data comprises in one aspect, a database storing at least recommended dose data and benchmark dose data for one or more facilities, a scanner located in one facility, the scanner can perform a scan with radiation dose data, an application server, a user interface comprising at least a display, and a module, operable on the processor, to receive the radiation dose data from the scanner, store the radiation dose data, monitor the radiation dose data in accordance with effective dose data and the benchmark dose data for the facilities, and display the monitored dose data and the benchmark dose data for the facility. In one aspect, convert the radiation dose data in accordance with the recommended dose data stored in the database and obtain an effective dose data based on the converted radiation dose data.

Abstract: Methods and compositions useful in reducing drug-induced sedation in subjects.

Abstract: Negative stiffness systems and methods for seismic protection of a structure is described. A system can include a negative stiffness device having a first linkage pivotably connected to an anchor frame at a first pivot point and pivotably connected the movement frame at a second pivot point. The negative stiffness device can include a spring having a first end operably coupled to the anchor frame and a second end operably coupled to a movement frame. In a rest state, the spring can be compressed to exert a preload force to the first linkage and the anchor frame and not displace the first linkage and the movement frame. In an engaged state, the spring can be configured to apply a force to the first linkage such that the movement frame is displaced in a same lateral direction of a seismic load. The spring force can be amplified by the first linkage.

Abstract: A p-channel tunneling field effect transistor (TFET) is selected from a group consisting of (i) a multi-layer structure of group IV layers and (ii) a multi-layer structure of group III-V layers. The p-channel TFET includes a channel region comprising one of a silicon-germanium alloy with non-zero germanium content and a ternary III-V alloy. An n-channel TFET is selected from a group consisting of (i) a multi-layer structure of group IV layers and (ii) a multi-layer structure of group III-V layers. The n-channel TFET includes an n-type region, a p-type region with a p-type delta doping, and a channel region disposed between and spacing apart the n-type region and the p-type region. The p-channel TFET and the n-channel TFET may be electrically connected to define a complementary field-effect transistor element. TFETs may be fabricated from a silicon-germanium TFET layer structure grown by low temperature (500 degrees Centigrade) molecular beam epitaxy.

Abstract: The invention provides methods to inhibit the replication of a flavivirus, methods of inhibiting the guanosine triphosphate (GTP)-binding and guanylyltransferase activity of a flavivirus RNA capping enzyme, and methods of treating a subject infected with a flavivirus. The methods can include contacting a flavivirus with an effective amount of a thioxothiazolidine compound described herein, or a derivative thereof, such as a compound of Formula (I).

Abstract: The invention relates to systems and methods for prioritizing video slices of H.264 video bitstream comprising: a memory storage and a processing unit coupled to the memory storage, wherein the processing unit operates to execute a low complexity scheme to predict the expected cumulative mean squared error (CMSE) contributed by the loss of a slice of H.

Abstract: A cryogenic cooling apparatus for high average power laser oscillator or amplifier, wherein the oscillator or amplifier material is in direct contact with a flowing cryogenic liquid cooled to below its boiling point is described. This method of cooling overcomes the limit in heat flux due to the onset of film boiling, thereby allowing for increased laser average power.

Abstract: Methods of inducing systemic acquired resistance to infection in a plant are provided. The methods comprise applying a composition comprising a Bacillus control agent to said plant wherein said plant is capable of producing defense proteins. Also provided are, methods for controlling one or more plant diseases, methods for preventing plant virus transmission, methods for preventing and/or treating soil-borne plant pathogens using the Bacillus control agent of the present invention, and methods of generating bacterial spores. In addition, synergistic biocontrol combinations and methods of using the same are provided.

Abstract: A method for producing a microbial growth stimulant (MGS) from a plant biomass is described. In one embodiment, an ammonium hydroxide solution is used to extract a solution of proteins and ammonia from the biomass. Some of the proteins and ammonia are separated from the extracted solution to provide the MGS solution. The removed ammonia can be recycled and the proteins are useful as animal feeds. In one embodiment, the method comprises extracting solubles from pretreated lignocellulosic biomass with a cellulase enzyme-producing growth medium (such T. reesei) in the presence of water and an aqueous extract.

Abstract: The disclosure provides for a method of testing a disinfectant or antibiotic using phenanthridium derivatives with a 2+ charge or higher.

Abstract: A gated microelectronic device is provided that has a source with a source ohmic contact with the source characterized by a source dopant type and concentration. A drain with a drain ohmic contact with the drain characterized by a drain dopant type and concentration. An intermediate channel portion characterized by a channel portion dopant type and concentration. An insulative dielectric is in contact with the channel portion and overlaid in turn by a gate. A gate contact applies a gate voltage bias to control charge carrier accumulation and depletion in the underlying channel portion. This channel portion has a dimension normal to the gate which is fully depleted in the off-state. The dopant type is the same across the source, drain and the channel portion of the device. The device on-state current is determined by the doping and, unlike a MOSFET, is not directly proportional to device capacitance.

Abstract: This disclosure concerns novel methods for preventing or treating neurological or neurodegenerative diseases or disorders by using kombo butter acid enriched extracts derived from the seeds of African nutmeg, the main active compounds isolated from the extracts, namely sargaquinoic acid, sargachromenol, and sargahydroquinoic acid, or synthetic analogs or derivatives thereof, as neuroprotective agents. The methods for preparing the kombo butter or kombo butter acid extracts and the methods for isolating and purifying the active compounds and for preparing their acetylated derivatives are also described.

Abstract: An apparatus for performing Raman spectral analysis of a sample is described, comprising a coherent light source, an first optical chain to direct the coherent light to impinge on the sample, a second optical chain to direct the scattered light onto a diffraction grating, and a third optical chain to direct the diffracted light onto detection array. The diffraction grating is a plurality of alternating-slope stairsteps, wherein the portion of the step disposed parallel to the base of the diffraction grating is disposed so as to be orthogonal to the path of the scattered light from the second optical chain. The zeroth-order fringe is selected by a slit and directed onto camera. The resultant interferogram is Fourier transformed to produce a representation of the Raman spectrum.

Abstract: The physical manner in which the inflorescences on our new cultivar are displayed is unique as the flower heads are held erect on the rapidly elongating peduncles in the spring at nearly 90 degrees. When the telescoped vegetative bracts that protected the over-wintering flower buds have fallen, the rapidly growing peduncles elongate upward and the rapidly growing narrow pink-red floral bracts which are lightly attached at their apex enlarge upward until, with further growth, the floral bracts expand at an increased angle and look like butterflies perched on the vertical peduncles. The deep-cup shape of the floral bracts is unique among the comparative pink/red bracted clones of C. kousa ‘Rosea’, ‘Radiant Rose’, and ‘Heart Throb’ in the trade It's floral bracts are larger and darker than the C. kousa in the trade and holds its color longer than those of C. kousa which usually turn white.