Abstract: An apparatus, resonator and method for modulating light including a mechanism to compensate for parameter deviations. The apparatus may be capable of phase shift keying and quadrature amplitude modulation, and includes a waveguide, a plurality of micro-resonators, and an electronic structure. The plurality of micro-resonators are positioned adjacent to the waveguide and have a parameter deviation in at least one resonator characteristic. The electronic structure is electrically biased so as to cause electro-optic modulation of amplitude and a phase of the light output by the apparatus, each bias voltage comprising a numerical offset that is determined based upon the parameter deviation, thereby reducing any overall effect caused by the material or manufacturing imperfections. An electronic encoder may provide driving voltage levels for phase shift keying or quadrature amplitude modulation. The number of output amplitude and phase states of light depends on the number of output voltage levels of the encoder.

Abstract: A system and method of management of communication in a potentially unreliable wide-area network that contains one or more nodes connected to said network, each potentially having access to one or more inputs and/or outputs and capable of evaluating said inputs and directing said outputs, a global address space (GAS) accessible by said nodes, and a communication system using said GAS that provides communications between said nodes.

Abstract: The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M. tuberculosis.

Abstract: A magnetic coupler is disclosed for wireless power transfer systems. A ferrimagnetic component is capable of guiding a magnetic field. A wire coil is wrapped around at least a portion of the ferrimagnetic component. A screen is capable of blocking leakage magnetic fields. The screen may be positioned to cover at least one side of the ferrimagnetic component and the coil. A distance across the screen may be at least six times an air gap distance between the ferrimagnetic component and a receiving magnetic coupler.

Abstract: Processes for the production of polyols from sources such as dried distillers grains plus solubles (DDGS) make use of a two-stage reaction scheme. In the first stage, the proteinaceous starting material is reacted with an aminating agent, such as diethanolamine (DEOA), to generate amino-amides and amides. These products are then reacted with an alkoxylating agent, preferably a substituted or unsubstituted epoxide to yield polyols. These polyols may be further reacted with isocyanates to give low-cost rigid polyurethane foams. In alternate forms, lignin may be directly converted to polyols by reaction with an alkoxylating agent, optionally followed by reaction with an isocyanate to produce polyurethanes.

Abstract: The present invention is directed to novel antifungal glycopeptide compounds and salts thereof produced by a strain of Burkholderia contaminans useful for preventing or treating fungal infection or disease in animals and plants and the bacterial strain that produces the compounds.

Abstract: This application discloses a light-responsive hydrogel-based platform that can modulate multiple microenvironmental signals to direct the differentiation of human induced pluripotent stem cell-derived neural progenitor cells (hiPSC-NPCs) into neuronal cells. The invention provides novel methods for directing differentiation of neural stem cells into neurons useful for treatment of degenerative diseases or disorders, including but not limited to Alzheimer's, Parkinson's, or spinal cord injury (SCI).

Abstract: A method and apparatus for classifying possibly vulnerable plaques from sets of DCE-MRI images includes receiving a set of MRI slice images obtained at respectively different times, where each slice image includes voxels representative of at least one region of interest (ROI). The images are processed to determine the boundaries of the ROIs and the voxels within the identified boundaries in corresponding regions of the images from each time period are processed to extract kinetic texture features. The kinetic texture features are then used in a classification process which classifies the ROIs as vulnerable or stable.

Abstract: The present invention provides isolated polynucleotides that can serve as translation enhancing elements and their use in protein expression reagents and methods.

Abstract: A system and method for predicting disease outcome by analyzing a large, heterogeneous image by a boosted, multi-field-of-view (FOV) framework, based on image-based features from multi-parametric heterogeneous images, comprises (a) inputting the heterogeneous image; (b) generating a plurality of FOVs at a plurality of fixed FOV sizes, the method for generating the plurality of FOVs at a plurality of fixed FOV sizes comprising dividing simultaneously, via the computing device, the large, heterogeneous image into (i) a plurality of FOVs at a first fixed FOV size from among the plurality of fixed FOV sizes; and (ii) a plurality of FOVs at a second fixed FOV size from among the plurality of fixed FOV sizes; (c) producing simultaneously for the heterogeneous image a combined class decision for: (i) the plurality of FOVs at the first fixed FOV size, and (ii) the plurality of FOV s at the second fixed FOV size.

Abstract: Composite materials are provided that include one or more CNT yarns embedded in a matrix material. The composite materials may be transparent. Methods for making the composite materials are also provided. The composite materials may be made by arranging at least one CNT yarn into a desired pattern and embedding the at least one CNT yarn into a matrix material.

Abstract: CXCR4 and ROBO-1 are biomarkers associated with type 1 diabetes. Expression of CXCR4 and ROBO-1 in peripheral CD3 T cells is substantially higher in patients with autoimmune diabetes (type 1 diabetes) than in non-diabetic patients. Therapies are disclosed for reducing the progression of type 1 diabetes, and to reduce the risk of developing type 1 diabetes in patients who are at risk of developing type 1 diabetes.

Abstract: A method of patterning an electrically-conductive film is performed by providing a flexible substrate that carries the electrically-conductive film thereon to form a combined layer. The combined layer is then bent about a radius of curvature, so as to impart a stress on the brittle conductive film along the axis of curvature of the curved surface. The application of the stress to the conductive film results in the formation of crack lines that are substantially perpendicular to the direction to which the substrate and conductive film are bent. The crack lines serve to define and electrically isolate conductive sections therebetween that can be utilized as electrodes and address lines in electronic devices.

Abstract: Provided in one embodiment is an electrochemical cell, comprising: (i) a plurality of electrodes, comprising a fuel electrode that comprises aluminum and an air electrode that absorbs gaseous oxygen, the electrodes being operable in a discharge mode wherein the aluminum is oxidized at the fuel electrode and oxygen is reduced at the air electrode, and (ii) an ionically conductive medium, comprising an organic solvent; wherein during non-use of the cell, the organic solvent promotes formation of a protective interface between the aluminum of the fuel electrode and the ionically conductive medium, and wherein at an onset of the discharge mode, at least some of the protective interface is removed from the aluminum to thereafter permit oxidation of the aluminum during the discharge mode.

Abstract: The present invention relates to the administration of compositions comprising polyethylene glycol, for improving the general gastrointestinal health of an animal increasing growth performance and treating osteopenia, osteoporosis and other bone disorders.

Abstract: For low complexity error correction, a decoder modifies each reliability metric of an input data stream with a random perturbation value. The reliability metric comprises a weighted sum of a channel measurement for the input data stream and parity check results for the input data stream. In addition, the decoder may generate an output data stream as a function of the reliability metrics.

Abstract: A robust method to automatically segment and identify tumor regions in medical images is extremely valuable for clinical diagnosis and disease modeling. In various embodiments, an efficient algorithm uses sparse models in feature spaces to identify pixels belonging to tumorous regions. By fusing both intensity and spatial location information of the pixels, this technique can automatically localize tumor regions without user intervention. Using a few expert-segmented training images, a sparse coding-based classifier is learned. For a new test image, the sparse code obtained from every pixel is tested with the classifier to determine if it belongs to a tumor region. Particular embodiments also provide a highly accurate, low-complexity procedure for cases when the user can provide an initial estimate of the tumor in a test image.

Abstract: Threshold logic elements and methods of operating the same are disclosed. In one embodiment, a threshold logic element includes a first input gate network configured to receive a first set of logical signals, a second input gate network configured to receive a second set of logical signals. The differential sense amplifier is operably associated with the first input gate network and the second input gate network such that the differential sense amplifier is configured to generate a differential logical output in accordance with a threshold logic function. In order to make the threshold logic element more robust, the differential sense amplifier is configured to feed back the differential logical output to the first input gate network and the second input gate network. By providing the differential logical output as feedback, floating node issues are avoided and the threshold logic element is more resistant to noise.

Abstract: A multiscale procedure models the growth of fluid-suspended particles through phase transition and/or agglomeration. The particle deposition on fluid flow boundaries and the precipitation occurred on the solid/liquid interface will influence and potentially constrict/block the fluid flow. The multiscale Lagrangian/Eulerian model enables detailed predictive simulations of the deposit formation and aging processes due to the continued precipitation on the deposit interface and deposition processes of precipitated solids, such as wax crystals or asphaltenes, on boundaries like walls exposed to fluid flow.

Abstract: This disclosure relates generally to threshold logic elements for integrated circuits (ICs). In one embodiment, a threshold logic element has a first input gate network, a second input gate network, a differential sense amplifier, and a resistive network. The first input gate network is configured to receive a first set of logical signals, while the second input gate network configured to receive a second set of logical signals. The differential sense amplifier is operably associated with the first input gate network and the second input gate network such that the differential sense amplifier is configured to generate a differential output in accordance with a threshold logic function. The resistive network is coupled between the differential sense amplifier and the first input gate network and between the differential sense amplifier and the second input gate network. The resistive network makes the threshold logic element less susceptible to process variations.