Abstract: This invention relates to the purified and isolated family of Rps1-k disease resistance genes, proteins encoded thereby and use of the same to confer, enhance or otherwise modify resistance of soybean to plant pathogens, particularly Phytophthora sojae.
Type:
Grant
Filed:
May 24, 2007
Date of Patent:
April 13, 2010
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.
Type:
Grant
Filed:
November 20, 2007
Date of Patent:
April 13, 2010
Assignee:
Board of Trustees of Michigan State University
Inventors:
Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
Abstract: The present invention is related to immunoglobulin peptides that recognize a thermostable antigen from bovine blood. The invention also provides methods for determining the presence of bovine blood in a food sample or an animal feed sample.
Type:
Grant
Filed:
December 27, 2006
Date of Patent:
April 13, 2010
Assignee:
Florida State University Research Foundation, Inc.
Abstract: A system for expression of a heterologous polypeptide in a transgenic host cell is disclosed. The system is based upon a transgene comprising a eukaryotic promoter operably linked to a DNA sequence comprising, in the 5? to 3? direction, a DNA sequence complementary to a sequence encoding a heterologous polypeptide, a DNA sequence complementary to an internal ribosome entry site, and a DNA sequence corresponding to a 3? untranslated region of a positive strand single-stranded RNA virus. Following introduction of a stimulus, the host cell synthesizes an RNA molecule complementary to a recombinant RNA encoded by the transgene. The stimulus can be a positive strand single-stranded RNA virus or a nucleic acid thereof. Because the complement of the recombinant RNA comprises an internal ribosome entry site and a sequence encoding a heterologous polypeptide, the host cell can synthesize the heterologous polypeptide.
Type:
Grant
Filed:
July 2, 2004
Date of Patent:
April 13, 2010
Assignee:
Board of Trustees Operating Michigan State University
Abstract: A process of forming a double strand cleavage in DNA includes providing a reaction mixture containing double stranded DNA having a break in a first strand defining a target site in a second strand. The method continues by adding to the reaction mixture a photoreactive lysine conjugate selected from a lysine-enediyne conjugate, a lysine-acetylene conjugate or a combination thereof, for a time sufficient for the lysine conjugate to bind to the DNA adjacent the target site. The reaction mixture is then irradiated with electromagnetic radiation sufficient to photoactivate the lysine conjugate to cleave the second strand adjacent the target site.
Type:
Grant
Filed:
December 22, 2006
Date of Patent:
April 13, 2010
Assignee:
Florida State University Research Foundation, Inc.
Inventors:
Igor V. Alabugin, Boris Breiner, Joerg C. Schlatterer, Serguei V. Kovalenko, Nancy L. Greenbaum
Abstract: A moisture-curable, silane-modified oil is disclosed. The silane-modified oil includes an unsaturated oil having at least one unsaturated aliphatic hydrocarbon chain per molecule of the unsaturated oil, and at least one hydrolysable silyl group grafted to the unsaturated aliphatic hydrocarbon chain. The silane-modified oil has a degree of unsaturation that is substantially similar that of the unsaturated oil. A process for forming the moisture-curable, silane-modified oil according to the disclosure includes reacting the unsaturated oil with an unsaturated hydrolysable silane in the presence of a free radical initiator. Also disclosed is a cured silane-modified oil which includes the reaction product of the silane-modified oil and water. Compositions according to the disclosure have relatively low viscosities (facilitating their application to a substrate) and have relatively high levels of silane grafting (resulting in non-leaching cured compositions with a high gel content).
Type:
Application
Filed:
October 6, 2008
Publication date:
April 8, 2010
Applicants:
Board of Trustees of Michigan State University, Bioplastic Polymers and Composites, LLC
Inventors:
Ramani Narayan, Daniel Graiver, Kenneth W. Farminer, Madhusudhan Srinivasan
Abstract: A process for the preparation of new polyols and polyesters from a natural oil or other unsaturated fatty acid esters is described. The process involves ozone cleavage of double bonds in the fatty acid chains of the oils along with coupling of a hydroxylated compound such as a mono-alcohol, a diol, or a polyol to the cleaved ends of the molecules resulting from the cleavage with a base. The resulting polyols and polyesters are as intermediates for polymers.
Type:
Application
Filed:
September 15, 2009
Publication date:
April 8, 2010
Applicants:
Board of Trustees of Michigan State University, Bioplastic Polymers and Composites, LLC
Inventors:
Ramani Narayan, Daniel Graiver, Kenneth W. Farminer, Phuong T. Tran, Tam Tran
Abstract: A new way of generating electrical power by changing the dielectric properties of liquid crystals by mechanical means is described. Such a method and device take advantage of the nature of the liquid crystal as the dielectric material in a capacitor. A broad range of materials, including various liquid crystalline materials, as well as additional mechanisms (flexoelectric polarization) to fully exploit the potential of this mechanism may be realized. Applications of this technology may be useful in wearable personal electric generators as well as in noise damping materials/devices, which not only absorb and dissipate sound, but use it to generate electric power.
Type:
Grant
Filed:
November 9, 2005
Date of Patent:
April 6, 2010
Assignee:
Kent State University
Inventors:
Peter Palffy-Muhoray, Antal Jakli, Bahman Taheri
Abstract: A method for producing a plurality of thin film actuators is disclosed. The method includes depositing a film of a shape memory alloy material onto a polyimide film to form a shape memory alloy construction. The shape memory alloy construction is strained from 2 to 8%. Post processing is conducted on the shape memory alloy construction after the step of imparting a 2 to 8% strain. This post processing can be the deposition of additional layers of the slicing of the actuators. Various shape memory metal actuators are disclosed.
Type:
Grant
Filed:
April 15, 2004
Date of Patent:
April 6, 2010
Assignee:
Board of Trustees Operating Michigan State University
Abstract: A machine and method for the continuous folding of sheet material into difference three-dimensional patterns is featured. The innovative machine and method folds sheet material by force converging the sheet to a final stage that imparts a final fold or pattern. Unique programming allows for the change of convergence sequencing and change of materials.
Type:
Grant
Filed:
November 2, 2005
Date of Patent:
April 6, 2010
Assignee:
Rutgers, The State University of New Jersey
Inventors:
Basily B. Basily, Elsayed A. Elsayed, Daniel Kling
Abstract: A series of novel, melt- or mold-processable HA esters with varying aliphatic chain lengths are synthesized from silyl HA-quaternary (quat.) ammonium salt complex (preferably silyl HA-CTA, a silylated HA complex with cetyltrimethyl ammonium salt). Introduction of aliphatic acyl groups, preferably acid chlorides, to disrupt the strong HA intermolecular bonding, is done via acylation. Acylation takes place at the oxygen of the trimethylsilyloxy group —O—Si(CH3)3 in the silyl HA-CTA by removal of trimethylsilyl groups therefrom. Optionally, crosslinking may be performed during the shaping/molding of the HA esters into a structure/device, or thereafter, if at all. Native HA can then be regenerated/recovered by saponification hydrolysis, removing acyl groups, —CH3(CH2)10CO, and the cetyltrimethyl ammonium salt groups, -CTA, from HA ester. The structure/device of a preselected shape (e.g.
Type:
Grant
Filed:
September 20, 2004
Date of Patent:
April 6, 2010
Assignee:
Colorado State University Research Foundation
Abstract: Compositions, methods, and vaccines that may stimulate the immune system and that may be used for treating malignancies associated with overexpression of the HER-2 protein are provided. Such compositions include epitopes of the HER-2 proteins.
Type:
Grant
Filed:
June 15, 2006
Date of Patent:
April 6, 2010
Assignee:
The Ohio State University Research Foundation
Abstract: An improved process for the production of ultralow density, high specific surface area gel products is provided which comprises providing, in an enclosed chamber, a mixture made up of small particles of material suspended in gas; the particles are then caused to aggregate in the chamber to form ramified fractal aggregate gels. The particles should have a radius (a) of up to about 50 nm and the aerosol should have a volume fraction (fv) of at least 10?4. In preferred practice, the mixture is created by a spark-induced explosion of a precursor material (e.g., a hydrocarbon) and oxygen within the chamber. New compositions of matter are disclosed having densities below 3.0 mg/cc.
Type:
Grant
Filed:
March 23, 2007
Date of Patent:
April 6, 2010
Assignee:
Kansas State University Research Foundation
Inventors:
Christopher M. Sorensen, Amitabha Chakrabarti, Rajan Dhaubhadel, Corey Gerving
Abstract: A method for inhibiting melanoma cell growth in a patient by administering to the patient a therapeutically effective amount of a glutamate release inhibitor, a GRM1 antagonist, or a combination thereof
Type:
Grant
Filed:
September 14, 2007
Date of Patent:
April 6, 2010
Assignee:
Rutgers, The State University of New Jersey
Abstract: A turbocharged engine includes an internal combustion engine and a variable geometry turbocharger. The turbocharger is adjustable to operate efficiently under various engine operating and environmental conditions. The turbocharger includes a turbine and compressor, with the compressor including a compressor housing, an impeller rotatably mounted in the housing, and an adjustable diffuser vane assembly. The diffuser vane assembly includes a plurality of pivotal diffuser vanes spaced about the impeller and a vane rotation drive that interconnects the vanes and permits simultaneous adjustment of the diffuser vanes to improve the efficiency and operating range of the turbocharger. The diffuser vane assembly also includes a vane locking drive operable to engage the pivotal vanes and prevent vane movement during turbocharger operation.
Type:
Application
Filed:
October 1, 2008
Publication date:
April 1, 2010
Applicant:
Kansas State University Research Foundation
Abstract: Certain embodiments provide a network waveform system that can include multiple radars disposed at different geographical positions within an environment. The multiple radars may be configured to transmit a network waveform. The network waveform may include multiple radar waveforms. Each radar waveform of the multiple waveforms may be transmitted by a specific radar of the multiple radars. The system can also include a computer system coupled with the multiple radars that can include a processor and a memory. The memory may be configured to store information including data received from the multiple radars, data processed by the processor, and processing code executable by the processor. The processing code may include instructions to receive output data from the multiple radars resulting from the transmitted network waveform instructions to jointly process the output data from the multiple radars to determine a measurement of the environment based on the network waveform.
Type:
Application
Filed:
May 7, 2009
Publication date:
April 1, 2010
Applicant:
Colorado State University Research Foundation
Abstract: The present invention relates to inhibiting angiogenesis with sulfur- or selenium-containing compounds, and polymeric forms thereof, in mammals including animals and humans. Sulfur- or selenium-containing compounds, and polymeric forms thereof, can be used alone or in combination with standard therapies to inhibit angiogenesis-mediated disorders. The present invention also relates to the combined use of sulfur- or selenium-containing compounds, and polymeric forms thereof, with other anti-angiogenesis agents, with various anti-inflammatory and cytotoxic agents as well as with radio-therapeutic agents in cancer, and with laser, photodynamic therapy for ocular-related disorders such as diabetic retinopathy or age-related macular degeneration.
Type:
Application
Filed:
June 30, 2006
Publication date:
April 1, 2010
Applicant:
The Research Foundation of the State University Of New York at Albany
Abstract: A turbocharged engine includes an internal combustion engine and a turbocharger powered by engine exhaust flow from the internal combustion engine to supply the engine with compressed intake air. The turbocharged engine further includes a turbocharger booster system with a dry low emissions burner. The burner fluidly communicates with an exhaust manifold of the engine and is operable to inject a combustion gas flow into the engine exhaust flow. The hot combustion gas flow is operable to increase the exhaust energy available to the turbocharger and thereby increase the output of compressed intake air.
Type:
Application
Filed:
October 1, 2008
Publication date:
April 1, 2010
Applicant:
Kansas State University Research Foundation
Inventors:
Kirby Chapman, Kyle Wolfram, Eric Figge
Abstract: The present invention relates to novel methods and compositions for detection and isolation of cancer cells with metastatic potential. The invention further relates to assays for measuring the metastatic potential of such cancer cells and drug screening assays for the identification of agents having anti-metastatic potential. The present invention further provides methods and compositions for inhibiting the metastatic potential of cancer cells by modulating the activity of serine integral membrane proteases [(SIMP) consisting of seprase and dipetidyl peptidase IV (DPPIV)] expressed on the surface of metastasizing cancer cells.
Type:
Grant
Filed:
December 10, 2004
Date of Patent:
March 30, 2010
Assignee:
The Research Foundation of State University of New York
Abstract: ‘Pink Storm’ is a new quince plant particularly distinguished by a medium-sized, upright, multi-stemmed shrub with occasional parthenocapic fruit formation, large, double-flowers with pink petals, and thornless stems, is disclosed.