Patents Assigned to State University
  • Systems for assessing and enhancing the performance of scanning probe microscopes by quantifying and enforcing symmetries and periodicities in two dimensions
    Patent number: 8196216
    Abstract: Scanning probe microscope (SPM) images are enhanced by enforcing one or more symmetries that can be selected based on suitable Fourier coefficient amplitude or phase angle residuals, and/or geometric Akaike information criteria, and/or cross correlation techniques. Alternatively, this selection can be based on prior knowledge of specimen characteristics. In addition, a scanning microscope point spread function is obtained based on the evaluation of a calibration image by enforcing at least one symmetry and can be applied to other image acquisitions.
    Type: Grant
    Filed: February 25, 2010
    Date of Patent: June 5, 2012
    Assignee: State of Oregon acting by and through the State Board of Higher Education on behalf of Portland State University
    Inventor: Peter Moeck
  • Assay system for monitoring the effects of genetically engineered cells to alter function of a synctium
    Patent number: 8192929
    Abstract: This invention provides methods for determining the ability of a gene construct to alter the rhythm and contractility of a syncytial cell. Furthermore, this invention provides methods for constructing a gene construct capable of altering the rhythm or contractility of a syncytial cell. Finally, this invention provides a method for constructing a gene construct capable of coupling to a syncytial cell.
    Type: Grant
    Filed: July 19, 2005
    Date of Patent: June 5, 2012
    Assignees: The Trustees of Columbia University in the City of New York, The Research Foundation of State University of New York
    Inventors: Richard B. Robinson, Michael R. Rosen, Ira S. Cohen, Peter R. Brink
  • AUTOMATED VIDEO SURVEILLANCE SYSTEMS
    Publication number: 20120133774
    Abstract: A video surveillance system includes a plurality of video sources, at least one processing server in communication with the video sources, and at least one monitoring station viewing video from the video sources. The video sources are distributed over a target area to be monitored by the surveillance system and are attached to a video network. The processing server allocates bandwidth to the video sources with an accuracy function which provides event/object detection accuracy as a function of image/video quality transferred over the network. The image accuracy is the accuracy with which the processing server identifies features in a video image. Bandwidth is allocated by optimizing the overall event/object detection accuracy by adjusting image/video quality for each video source optionally subject to the dynamic network conditions experienced by each video source.
    Type: Application
    Filed: June 9, 2010
    Publication date: May 31, 2012
    Applicant: WAYNE STATE UNIVERSITY
    Inventor: Nabil J. Sarhan
  • ALGAL MEDIUM CHAIN LENGTH FATTY ACIDS AND HYDROCARBONS
    Publication number: 20120135478
    Abstract: The present invention provides methods and compositions for production of algal-based medium chain fatty acids and hydrocarbons. More specifically, the invention relates to a Nannochloropsis algal strain and mutants that produces high amounts of C16 fatty acids and hydrocarbons. The present invention provides methods and compositions for production of algal-based medium chain fatty acids and hydrocarbons. More specifically, the invention relates to a Nannochloropsis algal strain and mutants that produces high amounts of C16 fatty acids and hydrocarbons.
    Type: Application
    Filed: July 29, 2011
    Publication date: May 31, 2012
    Applicant: Arizona Board of Regents for and on Behalf of Arizona State University
    Inventors: Qiang HU, Milton SOMMERFELD, Shan QIN
  • SYSTEMS AND METHODS FOR GLOBAL VOLTAGE SECURITY ASSESSMENT IN POWER SYSTEMS
    Publication number: 20120136643
    Abstract: Systems and methods for global voltage security assessment in power systems are disclosed herein. In one embodiment, a method for assessing voltage security in a power system having a number (i) of buses includes capturing a change in bus voltage and a change in line reactive power for at least some of the buses in the power system, for each of the i number of buses, calculating a voltage assessment index) (?i) for as follows: ? i = ? j ? ? ? ? Q ij ? ? ? V i where ?Vi is the change in bus voltage and ?Qij is the change in line reactive power from a connection j over a predetermined period of time. The method further includes assessing a current voltage security status of the power system based on the calculated voltage assessment index (?i).
    Type: Application
    Filed: May 23, 2011
    Publication date: May 31, 2012
    Applicant: Washington State University
    Inventors: Vaithianathan Venkatasubramanian, Xing Liu
  • Methods for Wafer Bonding, and for Nucleating Bonding Nanophases
    Publication number: 20120132263
    Abstract: Substrates may be bonded according to a method comprising contacting a first bonding surface of a first substrate with a second bonding surface of a second substrate to form an assembly; and compressing the assembly in the presence of an oxidizing atmosphere under suitable conditions to form a bonding layer between the first and second surfaces, wherein the first bonding surface comprises a polarized surface layer; the second bonding surface comprises a hydrophilic surface layer; the first and second bonding surfaces are different.
    Type: Application
    Filed: April 30, 2010
    Publication date: May 31, 2012
    Applicant: Arizona Board of Regents, a body Corporate acting for and on behalf of Arizona State University
    Inventors: Nicole Herbots, Robert J. Culbertson, James Bradley, Murdock Allen Hart, David Alexander Sell, Shawn David Whaley
  • FTY720-DERIVED ANTICANCER AGENTS
    Publication number: 20120136063
    Abstract: A number of FTY720-derived compounds with antitumor activity are described. These compounds include the compounds of formula I: wherein R1 is independently selected from the group consisting of hydrogen, methyl. methoxy, and hydroxyl; R2 is independently selected from the group consisting of hydrogen, methoxy, and hydroxyl; R3 is independently selected from the group consisting of alkyl and cyclo-alkyl; and n is independently selected from 0 to 6. The compounds have lower immunosuppressive side effects as a result of not being phosphorylated by sphingosine kinase 2.
    Type: Application
    Filed: November 29, 2011
    Publication date: May 31, 2012
    Applicant: The Ohio State University Research Foundation
    Inventors: Ching-Shih Chen, Samuel K. Kulp, Dasheng Wang, John C. Byrd, Natarajan Muthusamy
  • OREGANO AND MINT ANTI-INFLAMMATORY COMPOSITIONS AND METHODS
    Publication number: 20120135094
    Abstract: The present invention relates to bioactivity-guided isolation and identification of bioactive compounds from oregano and mint plants, in particular, rosmarinic acid, oleanolic acid and ursolic acid, and use of these compounds or combinations thereof as anti-inflammatory agents for the treatment of conditions related to pain and inflammation and/or as ingredients of dietary supplements. The invention also relates to optimization of the methods for qualitative and quantitative analysis of the bioactive compounds in oregano and mint plants. In particular, this invention introduces an LC/MS (SIM mode) method to achieve co-quantitation of the three organic acids using a unique tandem column system. In addition, the invention also relates to the methods for recovering various water-soluble polyphenols and triterpenes from aromatic plants.
    Type: Application
    Filed: May 14, 2010
    Publication date: May 31, 2012
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: James E. Simon, Diandian Shen, Hector Rodolfo Juliani, Qingli Wu
  • ELISA for Haptoglobin-Matrix Metalloproteinase 9 Complex as a Diagnostic Test for Conditions Including Acute Inflammation
    Publication number: 20120135425
    Abstract: A method for detecting a haptoglobin-matrix metalloproteinase 9 (Hp-MMP 9) complex in a biological sample. The sample includes incubating the biological sample with a capture reagent immobilized on a solid support to bind Hp-MMP 9 to the capture reagent. The capture reagent includes a monoclonal antibody that binds MMP9. The method detects Hp-MMP 9 bound to the immobilized capture reagent by contacting the bound Hp-MMP 9 with a detectable antibody that binds to Hp.
    Type: Application
    Filed: August 23, 2011
    Publication date: May 31, 2012
    Applicant: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Jeffrey Lakritz, Grigori Andreevich Bannikov, Tatiana Karelina
  • PREPARATION AND USES OF POLYARYLATES
    Publication number: 20120135523
    Abstract: The present invention is directed to polyarylates comprising repeating units having the structure: as well as their preparation and use as cell growth substrates.
    Type: Application
    Filed: January 30, 2012
    Publication date: May 31, 2012
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Ken James, Brochini Stephen, Varawut Tangpasuthadol, Joachim B. Kohn
  • ELECTROSPRAY IONIZATION MASS SPECTROMETRY METHODOLOGY
    Publication number: 20120132796
    Abstract: A method of enhanced speciation of both positive and negatives species in an analyte is disclosed. The method can include producing a first analyte solution comprising an analyte composition and an effective amount of silver triflate, and analyzing the first analyte solution with an electrospray ionization mass spectrometer. The method can also include producing a second analyte solution comprising a portion of the analyte composition and an effective amount of a compound of formula I, and analyzing the second analyte solution with an electrospray ionization mass spectrometer. The compound of formula I is [NX+][OH?], where X is a linear, branched, or cyclic C1-C10 alkane; an aryl; a heterocyclic aromatic; or a heterocyclic moiety.
    Type: Application
    Filed: February 6, 2012
    Publication date: May 31, 2012
    Applicant: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Alan G. MARSHALL, Priyanka JUYAL, Ryan P. RODGERS
  • DETECTION OF A COMPONENT OF INTEREST WITH AN ULTRAVIOLET LASER AND METHOD OF USING THE SAME
    Publication number: 20120135537
    Abstract: Means and method for analysis of a component of interest in a sample is provided. A small sample cell is provided which decreased dispersion of the sample. Also provided is a device for detection of a component of interest in a sample in which the small sample cell is used with an ultra violet laser in which the energy of the laser is spread over an area such that energy density is above desorption threshold, but the sample not ablated. Rapid and reliable detection of a component of interest is provided with the invention.
    Type: Application
    Filed: March 14, 2008
    Publication date: May 31, 2012
    Applicant: Arkansas State University Research and Development Institute
    Inventors: Matthew Horton, Robyn Hannigan
  • Medical devices for the detection, prevention and/or treatment of neurological disorders, and methods related thereto
    Patent number: 8190248
    Abstract: Disclosed are devices and methods for detecting, preventing, and/or treating neurological disorders. These devices and methods utilize electrical stimulation, and comprise a unique concentric ring electrode component. The disclosed methods involve the positioning of multiple electrodes on the scalp of a mammal; monitoring the mammal's brain electrical patterns to identify the onset of a neurological event; identifying the location of the brain electrical patterns indicative of neurological event; and applying transcutaneous or transcranial electrical stimulation to the location of the neurological event to beneficially modify brain electrical patterns.
    Type: Grant
    Filed: October 17, 2005
    Date of Patent: May 29, 2012
    Assignees: Louisiana Tech University Foundation, Inc., Board of Supervisors of Louisiana State University
    Inventors: Walter G. Besio, Mohammed Fasiuddin, Ravish Patwardhan
  • Enduracidin biosynthetic gene cluster from
    Patent number: 8188245
    Abstract: This disclosure describes the molecular cloning of an enduracidin biosynthetic gene cluster from Streptomyces fungicidicus, and characterization of individual genes in the gene cluster and the proteins encoded thereby. An enduracidin gene cluster is located within a 116 kilobases genetic locus and includes 25 open reading frames (ORFs). An additional 23 ORFs flank the disclosed enduracidin biosynthetic gene cluster. Enduracidin analogs and a method for producing them by manipulation of the enduracidin gene cluster and specific genes therein are also disclosed.
    Type: Grant
    Filed: October 1, 2007
    Date of Patent: May 29, 2012
    Assignee: State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University
    Inventors: Xihou Yin, T. Mark Zabriskie
  • Synthetic route to ABCD-porphyrins
    Patent number: 8188298
    Abstract: A method of making a metalloporphyrin is carried out by reacting (i) a linear tetrapyrrole, said linear tetrapyrrole having a 19-acyl group and a 1-protecting group, with (ii) a metal salt under basic conditions to produce the metalloporphyrin. Products produced by such methods and intermediates useful for carrying out such methods are also described.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: May 29, 2012
    Assignee: North Carolina State University
    Inventors: Jonathan S. Lindsey, Dilek Dogutan Kiper
  • Association of GSTM1 with autism and assays and methods based thereon
    Patent number: 8187806
    Abstract: The present invention provides novel markers and assays for autism based on the association of GSTM1 with autism. The invention relates to the use and application of as a susceptibility marker for autism. GSTM1 may be combined with other markers in methods and assays for diagnosis, prenatal diagnosis, and assessment of autism. The invention further relates to a likelihood ratio test. In addition, the present invention discloses a novel method for identifying individuals who are genetically susceptible to have offspring with autism wherein the genotype of GSTM1, alone or in combination with other genetic markers, is determined.
    Type: Grant
    Filed: February 11, 2008
    Date of Patent: May 29, 2012
    Assignees: University of Medicine and Dentistry of New Jersey, Rutgers, The State University of New Jersey
    Inventors: Steven Buyske, Edward S. Stenroos, William G. Johnson
  • Porphyrinic compounds for use in flow cytometry
    Patent number: 8187824
    Abstract: The present invention provides a method of detecting (e.g., by flow cytometry) a target compound, cell or particle, wherein the target is labelled with a detectable luminescent compound. The method comprises utilizing as the detectable luminescent compound a compound comprising a porphyrinic macrocycle such as a porphyrin, chlorin, bacteriochlorin, or isobacteriochlorin. In particular embodiments, the detectable luminescent compound comprises a compound of the formula A-A?-Z—B?—B, wherein: A is a targeting group or member of a specific binding pair that specifically binds the detectable luminescent compound to the target compound, cell or particle; A? is a linker group or covalent bond; B? is a linker group or covalent bond; B is a water-soluble group; and Z is the porphyrinic macrocycle.
    Type: Grant
    Filed: November 30, 2006
    Date of Patent: May 29, 2012
    Assignee: North Carolina State University
    Inventor: Jonathan S. Lindsey
  • Methods, systems, and computer program products for binary multiplexing x-ray radiography
    Patent number: 8189893
    Abstract: Methods, systems, and computer program products for binary multiplexing x-ray radiography are disclosed. According to one aspect, the subject matter described herein can include irradiating an object with composite x-ray beams including signals based on a predetermined binary transform. Further, the subject matter described herein can include detecting x-ray intensities associated with the signals of the composite x-ray beams. An inverse binary transform can be applied to the detected x-ray intensities associated with the signals of the composite x-ray beams to recover the signals of the composite x-ray beams.
    Type: Grant
    Filed: May 21, 2007
    Date of Patent: May 29, 2012
    Assignees: The University of North Carolina at Chapel Hill, North Carolina State University
    Inventors: Jian Zhang, Jianping Lu, Otto Z. Zhou, David Lalush
  • Thermionic electron emitters/collectors have a doped diamond layer with variable doping concentrations
    Patent number: 8188456
    Abstract: A thermionic electron emitter/collector includes a substrate and a doped diamond electron emitter/collector layer on the substrate. The doped diamond electron emitter/collector layer has at least a first and a second doping concentration as a function of depth such that the first doping concentration is different from the second doping concentration.
    Type: Grant
    Filed: February 12, 2008
    Date of Patent: May 29, 2012
    Assignee: North Carolina State University
    Inventors: Robert J. Nemanich, Franz A. M. Koeck
  • Cell lines useful for assessing modulation of autophagy
    Patent number: 8187802
    Abstract: Methods for screening for modulators of autophagy are disclosed. Methods for identifying genes whose expression inhibits autophagy, as well as genes whose expression promotes autophagy, are disclosed. Also disclosed are methods for identifying compounds that stimulate autophagy, as well as compounds that inhibit autophagy. Cell lines that may be used in the methods of identification are also disclosed.
    Type: Grant
    Filed: November 19, 2009
    Date of Patent: May 29, 2012
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Eileen White, Anne Marie Strohecker, Robin Mathew, Cristina Karp