Patents Assigned to State University
  • Publication number: 20120101255
    Abstract: The present invention relates to proteins and polypeptides as well as methods of using these proteins and polypeptides to: identify the location of an RXP-binding domain of Cx43CT, modulate a Cx43 gap junction channel, screen for compounds that modulate Cx43CT, and measure Cx43CT-binding affinity of a compound that binds to Cx43CT.
    Type: Application
    Filed: October 24, 2011
    Publication date: April 26, 2012
    Applicants: Zealand Pharma A/S, The Research Foundation of State University of New York
    Inventors: Mario Delmar, Steven M. Taffet, Bjarne Due Larsen
  • Publication number: 20120098974
    Abstract: Described is a calibration standard for determining the height of fluorescent microstructures, methods of using such a calibration standard, and a method of making such a calibration standard.
    Type: Application
    Filed: September 16, 2011
    Publication date: April 26, 2012
    Applicant: Florida State University Research Foundation
    Inventors: STEVEN LENHERT, Omkar A. Nafday
  • Publication number: 20120096631
    Abstract: Protective headgear includes an outer shell rotatable relative to an inner shell via a thin layer of elastically and/or plastically yielding material disposed between and secured to the inner and outer shells. The yielding material deforms continuously but non-linearly at least in the tangential or shear direction to mitigate angular acceleration of the head during an impact. The yielding material prevents the inner and outer shells from separating or stopping suddenly to avoid imparting a large angular acceleration to the head. In one embodiment, a protective helmet includes an outer shell secured to an inner shell by a yielding material that elastically deforms continuously but non-linearly when subjected to an angular acceleration below a first threshold and plastically deforms when subjected to an angular acceleration above the first threshold.
    Type: Application
    Filed: June 24, 2010
    Publication date: April 26, 2012
    Applicant: WAYNE STATE UNIVERSITY
    Inventors: Albert I. King, King Hay Yang, Liying Zhang
  • Publication number: 20120097961
    Abstract: Methods of anodizing aluminum using a hard mask and related embodiments of semiconductor devices are disclosed herein. Other methods and related embodiments are also disclosed herein.
    Type: Application
    Filed: December 7, 2011
    Publication date: April 26, 2012
    Applicants: Arizona State University
    Inventors: Jovan Trujillo, Curtis Moyer
  • Publication number: 20120101418
    Abstract: A compression splint is provided for reduction, compression and stabilization of spinal, pelvic, and long bone fractures. The compression splint includes a plurality of plates selectively disposed at a plurality of positions of a fracture site; a plurality of inflatable cushions, each cushion positioned between respective plates of the plurality of plates and the fracture site; and a support means for supporting the plurality of plates and plurality of cushions compressively against the fracture site in three dimensions, Additionally, the plates of the compression splint can be adjusted, removed or additional plates added to further customize the compressive force applied to the fracture site.
    Type: Application
    Filed: August 13, 2009
    Publication date: April 26, 2012
    Applicant: The Research Foundation of State University of New
    Inventors: Seth M. Manoach, Elton Strauss
  • Publication number: 20120097209
    Abstract: The invention relates to a new method of texturing silicon surfaces suited for antireflection based on ion implantation of hydrogen and heavy ions or heavy elements combined with thermal annealing or thermal annealing and oxidation. The addition of the heavy ions or heavy elements allows for a more effective anti-reflective surface than is found when only hydrogen implantation is utilized. The methods used are also time- and cost-effective, as they can utilize already existing semiconductor ion implantation fabrication equipment and reduce the number of necessary steps. The antireflective surfaces are useful for silicon-based solar cells.
    Type: Application
    Filed: October 24, 2011
    Publication date: April 26, 2012
    Applicant: The Research Foundation of State University of New York
    Inventors: Mengbing HUANG, Nirag KADAKIA, Sebastian NACZAS, Hassaram BAKHRU
  • Publication number: 20120100068
    Abstract: Disclosed are compositions that include anti-CD74 immunoconjugates and optionally a therapeutic and/or diagnostic agent. In preferred embodiments, the immunoconjugates comprise one or more anti-CD74 antibodies or antigen-binding fragments thereof, conjugated to a liposome or micelle. Also disclosed are methods for preparing the immunoconjugates and using the immunoconjugates in diagnostic and therapeutic procedures. In certain preferred embodiments, the therapeutic methods comprise administering to a subject with a CD74-expressing disease an anti-CD74 immunoconjugate and thereby inducing apoptosis of CD74-expressing cells. In more preferred embodiments, the CD74 immunoconjugate is capable of inducing cell death in the absence of any other therapeutic agent, although such agents may be optionally administered prior to, together with or subsequent to administration of the anti-CD74 immunoconjugate. The compositions may be part of a kit for administering the anti-CD74 immunoconjugates or compositions.
    Type: Application
    Filed: January 11, 2012
    Publication date: April 26, 2012
    Applicants: IMMUNOMEDICS, INC., THE OHIO STATE UNIVERSITY
    Inventors: John C. Byrd, David M. Goldenberg, Hans J. Hansen
  • Patent number: 8163156
    Abstract: The inventive method and device for vacuum-compression micro plasma oxidation relate to electrochemical processing of metal, in particular to micro plasma treatment in electrolyte solutions. The aim of said invention is to develop a method for obtaining qualitatively homogeneous coatings by micro-plasma oxidation on large-sized parts, including irregular shaped parts, or simultaneously on a great number of small parts. The second aim of the invention is to design a device for processing parts, having an extended surface area, by using low-power supplies. The inventive method for vacuum-compression micro-plasma oxidation of parts consists in dipping a processable part into an electrolyte solution pre-filled in a sealed container, in generating micro-plasma discharges on the surface of said part and, subsequently, in forming a coating, wherein the micro-plasma discharges are formed in low-pressure conditions above the electrolyte solution.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: April 24, 2012
    Assignees: Tomsk State University (TSU), Sibspark, Limited Liability Company
    Inventors: Anatoli Ivanovich Mamaev, Vera Aleksandrovna Mamaeva, Pavel Igorevich Butyagin
  • Patent number: 8164345
    Abstract: Design for testability (DFT) algorithms, which use both gradient descent and linear programming (LP) algorithms to insert test points (TPs) and/or scanned flip-flops (SFFs) into large circuits to make them testable are described. Scanning of either all flip-flops or a subset of flip-flops is supported. The algorithms measure testability using probabilities computed from logic simulation, Shannon's entropy measure (from information theory), and spectral analysis of the circuit in the frequency domain. The DFT hardware inserter methods uses toggling rates of the flip-flops (analyzed using digital signal processing (DSP) methods) and Shannon entropy measures of flip-flops to select flip-flops for scan. The optimal insertion of the DFT hardware reduces the amount of DFT hardware, since the gradient descent and linear program optimizations trade off inserting a TP versus inserting an SFF.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: April 24, 2012
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Michael L. Bushnell, Raghuveer Ausoori, Omar Khan, Deepak Mehta, Xinghao Chen
  • Patent number: 8163870
    Abstract: The present invention provides a family of peptides based upon the M2GlyR sequence. These peptides are derivatives of the M2GlyR sequence and can be modified at their ends to include a plurality of polar amino acid residues to enhance their solubility. Particularly preferred derivatives include portions of the M2GlyR sequence which are palindromic to another portion of the peptide or to the M2GlyR sequence itself. Preferably these portions are at least 7 amino acid residues in length. Peptides embraced by the present invention are characterized by having greater effects on the transepithelial electrical resistance of cells at lower concentrations. Peptides of the present invention have been shown to increase Isc in MDCK epithelial cell monolayers with half maximal effects observed at or below 30 ?M, a nearly 10-fold improvement over any peptide previously characterized in the M2GlyR family.
    Type: Grant
    Filed: June 14, 2004
    Date of Patent: April 24, 2012
    Assignee: Kansas State University Research Foundation
    Inventors: John M. Tomich, Iwamoto Takeo, James R. Broughman, Bruce D. Schultz
  • Patent number: 8163946
    Abstract: A method of forming a biodiesel product and a heterogeneous catalyst system used to form said product that has a high tolerance for the presence of water and free fatty acids (FFA) in the oil feedstock is disclosed. This catalyst system may simultaneously catalyze both the esterification of FAA and the transesterification of triglycerides present in the oil feedstock. The catalyst system according to one aspect of the present disclosure represents a class of zinc and lanthanum oxide heterogeneous catalysts that include different ratios of zinc oxide to lanthanum oxides (Zn:La ratio) ranging from about 10:0 to 0:10. The Zn:La ratio in the catalyst is believed to have an effect on the number and reactivity of Lewis acid and base sites, as well as the transesterification of glycerides, the esterification of fatty acids, and the hydrolysis of glycerides and biodiesel.
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: April 24, 2012
    Assignee: Wayne State University
    Inventors: Shuli Yan, Steven O. Salley, K. Y. Simon Ng
  • Patent number: 8164359
    Abstract: Embodiments of a threshold logic element are provided. Preferably, embodiments of the threshold logic element discussed herein have low leakage power and high performance characteristics. In the preferred embodiment, the threshold logic element is a threshold logic latch (TLL). The TLL is a dynamically operated current-mode threshold logic cell that provides fast and efficient implementation of digital logic functions. The TLL can be operated synchronously or asynchronously and is fully compatible with standard Complementary Metal-Oxide-Semiconductor (CMOS) technology.
    Type: Grant
    Filed: February 13, 2009
    Date of Patent: April 24, 2012
    Assignee: Arizona Board of Regents for and on behalf of Arizona State University
    Inventors: Samuel Leshner, Sarma Vrudhula
  • Patent number: 8164512
    Abstract: Embodiments of the present invention provide a Gaussian adaptive filter for ground clutter filtering and signal parameter estimation for weather radars in the time domain. In some embodiments, the filtering can be applied to dual polarization radar systems. In some embodiments, the clutter component of the signal can be transformed to noise. An interpolation procedure can then be used to recover the transformed part of the weather. A unique filter can be designed to use for both H and V channels for dual-polarization parameter estimation. In addition, the filter can be directly extended for staggered PRT 2/3 sampling scheme.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: April 24, 2012
    Assignee: Colorado State University Research Foundation
    Inventors: Chandrasekaran Venkatachalam, Cuong M. Nguyen
  • Patent number: 8163263
    Abstract: Methods and processes for synthesizing single-wall carbon nanotubes are provided. A carbon precursor gas is contacted with metal catalysts deposited on a support material. The metal catalysts are preferably nanoparticles having diameters less than about 3 nm. The reaction temperature is selected such that it is near the eutectic point of the mixture of metal catalyst particles and carbon. Further, the rate at which hydrocarbons are fed into the reactor is equivalent to the rate at which the hydrocarbons react for given synthesis temperature. The methods produce carbon single-walled nanotubes having longer lengths.
    Type: Grant
    Filed: January 30, 2007
    Date of Patent: April 24, 2012
    Assignees: Honda Motor Co., Ltd., The Ohio State University Research Foundation
    Inventors: Avetik R. Harutyunyan, Toshio Tokune, Elena Mora
  • Patent number: 8164629
    Abstract: The present invention features a qualitative method to detect independent motion revealed in successive frames of a compressed surveillance MPEG video stream using linear system consistency analysis without decompression of the stream, identifying the segments containing independent motion in a real-time or faster manner, for the retrieval of these segments. The linear system is constructed using the macroblocks of MPEG compressed video frames. The normal flow value of the macroblock is obtained by taking the dot product between the macroblock gradient vector, computed by averaging the four block gradient vectors, and the motion vector of this macroblock. The normal flow value is filtered for inclusion in the linear system, and the statistic of the matrices of the resulting linear system is determined, filtered to screen out false negatives and outliers, and used to determine the presence or absence of independent motion.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: April 24, 2012
    Assignee: The Research Foundation of State University of New York
    Inventor: Zhongfei Zhang
  • Patent number: 8161843
    Abstract: A torque damper motor connected to the output side of a mechanical gear system. The damper motor, along with its associated control system, mitigates backlash problems, reduced torsional resonance, and provides improved output torque control. In the preferred embodiment, the damper motor is powered by a power electronics-based variable speed drive. The damper motor can be significantly less powerful than the overall rating of the gear system (typically 5-10% of the overall rating) while still providing the enhanced performance.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: April 24, 2012
    Assignee: Florida State University Research Foundation
    Inventor: Michael Steurer
  • Publication number: 20120093718
    Abstract: Formulations of neutral retinoids, in particular fenretinide (HPR) in the form of lipid nanoparticles, solid dipersions and emulsions are disclosed. These compositions are used to treat diseases that are amenable to treatment by HPR, such as neoplastic diseases by achieving higher and more prolonged concentrations of HPR in the subject. The key steps for preparing lipid nanovesicles of HPR include mixing and sonication, sterile filtration, without or without lyophilization for long-term stable storage, and employ processes and materials that are scalable from the laboratory to the manufacturing level. The formulation are suitable for injection into human or animal patients without causing allergic or hypersensitivity responses by avoiding chemical surfactants and animal sources of phospholipids in their manufacture.
    Type: Application
    Filed: March 29, 2007
    Publication date: April 19, 2012
    Applicants: SCITECH DEVELOPMENT, LLC, WAYNE STATE UNIVERSITY
    Inventors: Ralph E. Parchment, Bhaskara R. Jasti, Ramesh R. Boinpally, Stephen E. Rose, Earle T. Holsapple
  • Publication number: 20120093919
    Abstract: The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided.
    Type: Application
    Filed: October 14, 2011
    Publication date: April 19, 2012
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
    Inventors: Joseph R. Bertino, Debabrata Banerjee, Tamara Minko, Olga B. Garbuzenko, Xiaoqi Xie, John E. Kerrigan, Emine E. Abali, Kathleen W. Scotto
  • Publication number: 20120096220
    Abstract: An improved technique is provided for compressing a packet classifier for a computer network system. A set of packet classification rules is first partitioned into one or more partitions. For each partition, columns of bits in each of the ternary strings of a given partition are reordered, the ternary strings within each partition are consolidated into one or more replacement strings and then the columns of bits of the replacement strings are rearranged back to the starting order. The rearranged replacement strings from each of the partitions are appended together to form a compressed packet classifier which may be instantiated in a content-addressable memory device.
    Type: Application
    Filed: January 6, 2011
    Publication date: April 19, 2012
    Applicant: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Xiang-Yang A. Liu, Chad R. Meiners, Eric Torng
  • Publication number: 20120090231
    Abstract: The present invention provides transgenic cover crop plants which after harvest degrade the hemicellulose and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise cellulase, hemicellulase and optionally ligninase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular, the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the hemicellulase and cellulase which then degrade the hemicellulose and cellulose of the transgenic plants to produce the fermentable sugars.
    Type: Application
    Filed: October 19, 2011
    Publication date: April 19, 2012
    Applicant: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventor: Masomeh B. Sticklen