Abstract: An auscultation system comprises an auscultation device comprising a wearable apparatus positionable proximate to a lung, a plurality of audio sensors embedded in the wearable apparatus configured to record lung sounds, wherein the plurality of audio sensors are positioned at locations of the wearable apparatus corresponding to lung auscultation points, and a computing system communicatively connected to the auscultation device, comprising a processor and a non-transitory computer-readable medium with instructions stored thereon, which when executed by a processor, perform steps comprising, establishing a background noise spectrum, recording a lung sound spectrum via the auscultation device for a period of time, calculating a background subtracted lung sound spectrum by subtracting the background noise spectrum from the measured lung sound spectrum, analyzing the background subtracted lung sound spectrum to produce an auscultation result, and providing the auscultation result to a practitioner to assist in pr
Type:
Application
Filed:
June 29, 2023
Publication date:
January 4, 2024
Applicant:
Arizona Board of Regents on behalf of Arizona State University
Abstract: An apparatus for a high-power reflexive field containment circuit topology for dynamic wireless power transfer systems is disclosed. A wireless power transfer (“WPT”) charging apparatus includes an inverter configured to connect with a direct current (“DC”) source on an input side and one or more WPT charging branches. Each WPT charging branch includes a WPT charging pad circuit with a WPT charging pad connected in series with a first series charging capacitor, a parallel charging capacitor connected in parallel with the WPT charging pad circuit, and a series charging impedance connected in series between an output of the inverter and a connection between the WPT charging pad circuit and the parallel charging capacitor. The series charging impedance includes a second series charging capacitor and/or a series charging inductor.
Abstract: This patent discloses a medical service platform, method, and apparatus based on a human digital twin model that comprises a a data currency valuation subsystem that provides dynamic quotes of a digital currency based on values of corresponding data in the digital human digital data currency system.
Type:
Application
Filed:
June 30, 2023
Publication date:
January 4, 2024
Applicants:
Rutgers, The State University of New Jersey, Digital Health China Technologies, Co., Ltd.
Inventors:
Jing Jin, Wenzhao Shi, Anjiang Chen, Juan Xu, Yi Ge, Zheng Xu
Abstract: A multifunctional oxide based negative capacitance thin film transistor (NC-TFT) is built on glass or on flexible substrates, instead of on the single crystal substrates. It is therefore suitable for low-cost and large-area electronics, transparent electronics, or flexible electronics applications. The NC-TFT includes a semiconductor Magnesium Zinc Oxide (MZO) as the channel layer and a Nickel doped MZO ferroelectric material (NMZO) as the gate dielectric layer. Also disclosed are articles of manufacture methods of building the NC-TFT on glass and its transparent version NC-TTFT on glass.
Type:
Application
Filed:
August 23, 2021
Publication date:
January 4, 2024
Applicant:
Rutgers, The State University of New Jersey
Inventors:
Yicheng Lu, Fangzhou Yu, Wen-Chiang Hong
Abstract: Provided herein are methods of modulating temperature in detection fields and producing analyte imaging data. In some embodiments, the methods include introducing an incident light toward a second surface of a substrate to induce a plasmonic wave proximal to a first surface of the substrate such that a temperature in a selected heating space within the detection field is substantially uniformly changed to a selected temperature. Additional methods as well as related systems and computer readable media are also provided.
Type:
Application
Filed:
June 21, 2023
Publication date:
January 4, 2024
Applicant:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: Various embodiments of a variable geometry quadrotor with a compliant frame are disclosed, which adapts to tight spaces and obstacles by way of passive rotation of its arms.
Type:
Application
Filed:
September 1, 2023
Publication date:
January 4, 2024
Applicant:
Arizona Board of Regents on behalf of Arizona State University
Abstract: A new set of bench-stable fluoroalkylphosphines that directly convert C—H bonds in pyridine building blocks, drug-like fragments, and pharmaceuticals, into fluoroalkyl derivatives. No pre-installed functional groups or directing motifs are required. The reaction tolerates a variety of sterically and electronically distinct pyridines and is exclusively selective for the 4-position in most cases. The reaction proceeds via initial phosphonium salt formation followed by sp2-sp3 phosphorus ligand-coupling, an underdeveloped manifold for C—C bond formation.
Type:
Application
Filed:
September 8, 2023
Publication date:
January 4, 2024
Applicant:
COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
Inventors:
Andrew MCNALLY, Kyle NOTTINGHAM, Chirag PATEL, Jeffrey LEVY, Xuan ZHANG
Abstract: Solvent free epoxy system that includes: a hardener compound H comprising: a molecular structure (Y1—R1—Y2), wherein R1 is an ionic moiety Y1 is a nucleophilic group and Y2 nucleophilic group; and an ionic moiety A acting as a counter ion to R1; and an epoxy compound E comprising: a molecular structure (Z1—R2—Z2), wherein R2 is an ionic moiety, Z1 comprises an epoxide group, and Z2 comprises an epoxide group; and an ionic moiety B acting as a counter ion to R2. In embodiments, the epoxy compound E and/or the hardener H is comprised in a solvent-less ionic liquid. The systems can further include accelerators, crosslinkers, plasticizers, inhibitors, ionic hydrophobic and/or super-hydrophobic compounds, ionic hydrophilic compounds, ionic transitional hydrophobic/hydrophilic compounds, biological active compounds, and/or plasticizer compounds. Polymers made from the disclosed epoxy systems and their methods of used.
Type:
Grant
Filed:
April 9, 2021
Date of Patent:
January 2, 2024
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Inventors:
Cody Friesen, Jose Antonio Bautista-Martinez, Mykhaylo Goncharenko, Paul Johnson
Abstract: An active vortex generator adapts to a flow rate of fluid through and/or a heat flux applied through a heat exchanger channel to improve the heat transfer rate of the heat exchanger. In some implementations, the movement of the active vortex generator may be induced by the fluid flow through the heat exchanger channel. In some implementations, the movement of the active vortex generator may be induced through an externally applied force on the active vortex generator. An actuated active vortex generator is particularly suited to heat exchangers with high heat flux dissipation requirements. Locating an actuated active vortex generator proximate to such high heat flux dissipation locations provides for improved heat transfer that can be activated when needed, such as upon operation of a high heat flux component.
Type:
Grant
Filed:
December 6, 2022
Date of Patent:
January 2, 2024
Assignee:
The Florida State University Research Foundation, Inc.
Abstract: A testing apparatus for dynamic characterization of a sample of a material under test. A terahertz (THz) time-domain spectroscopy system is configured and arranged to generate and detect terahertz waves to interrogate the sample. A shock wave loading system is configured and arranged to produce a shock wave in the sample concurrently with said THz spectroscopy device interrogating the sample. The sample undergoes changes in an index of refraction in response to the produced ultrafast shock wave in the sample that are detected by the terahertz spectroscopy system.
Type:
Grant
Filed:
October 30, 2020
Date of Patent:
January 2, 2024
Assignee:
SAN DIEGO STATE UNIVERSITY (SDSU) FOUNDATION
Abstract: A product includes a material having: nickel and at least one rare earth element. The at least one rare earth element is present in the material in a weight percentage in a range of about 2% to about 20% relative to a total weight of the material. A method includes forming a material comprising an alloy of nickel and at least one rare earth element. The at least one rare earth element is present in the material in a weight percentage in a range of about 2% to about 20% relative to a total weight of the material.
Type:
Grant
Filed:
February 25, 2022
Date of Patent:
January 2, 2024
Assignees:
Lawrence Livermore National Security, LLC, Eck Industries, Inc., Iowa State University Research Foundation, Inc., University of Tennessee Research Foundation, UT-Battelle, LLC
Inventors:
Scott K. McCall, Alexander Baker, Hunter B. Henderson, Tian Li, Aurelien Perron, Zachary Cole Sims, David Weiss, Ryan T. Ott, Orlando Rios, Max Neveau
Abstract: In certain embodiments, the present invention provides a poultry vaccine comprising an antigenic protein comprising a PlcC protein unit that is operably linked to a peptide linker that is operably linked to a NetB protein unit, where the vaccine is effective in stimulating a protective cellular and/or humoral immune response to C. perfringens. Methods are also provided for making the vaccine and for vaccinating poultry by administering such a vaccine.
Type:
Grant
Filed:
December 27, 2022
Date of Patent:
January 2, 2024
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF ARIZONA STATE UNIVERSITY
Inventors:
Kenneth Roland, Andrew Diamos, Hugh Mason
Abstract: An induction machine with localized voltage unbalance compensation is disclosed. The use of an induction machine with a voltage unbalance correction compensator (VUC) may be used to maintain proper working conditions of the machine during intervals of voltage unbalance.
Type:
Grant
Filed:
May 10, 2020
Date of Patent:
January 2, 2024
Assignee:
Florida State University Research Foundation, Inc.
Abstract: A probe generates location signals, and has an electrode at a distal end that acquires from heart chamber surface positions electrical signals due to a conduction wave traversing the surface. A processor derives LATs from the electrical signals, calculates a first time difference between LATs at a first pair of positions and a second time difference between LATs at a second pair of positions. The processor calculates first and second LAT-derived distances as products of the first and second time differences with a conduction wave velocity, identifies an arrhythmia origin at a surface location where a first difference in distances from the location to the first pair of the positions is equal to the first LAT-derived distance, and a second difference in distances from the location to the second pair of the positions is equal to the second LAT-derived distance, and marks the origin on a surface representation.
Type:
Grant
Filed:
August 8, 2022
Date of Patent:
January 2, 2024
Assignees:
BIOSENSE WEBSTER (ISRAEL) LTD., RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Inventors:
Gal Hayam, Michael Timofeyev, Tal Haim Bar-On, Amardeep Saluja
Abstract: An ingress-egress apparatus for protection of a surgical work site during removal of a surgical implant therefrom includes an inverted frustum surface having a sidewall defining: a bottom open area at a base portion of the frustum surface sidewall, and an opposing top open area at a top portion of the frustum surface sidewall. The top open area has a larger area than the bottom open area. The apparatus includes an ingress port located at the base portion of the frustum surface sidewall and an egress port located at the base portion of the frustum surface sidewall. During surgical removal of the surgical implant using a surgical burr, the apparatus can be used to irrigate the work site, thereby cooling it and protecting it from damage, and further removing metal implant particles generated during burring.
Type:
Grant
Filed:
December 6, 2021
Date of Patent:
January 2, 2024
Assignee:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Abstract: This disclosure provides compounds, pharmaceutical compositions, and methods of use for the prevention and treatment of inflammatory diseases or degenerative diseases including neurodegenerative diseases. Embodiments of the present disclosure provide compounds related to very long chain polyunsaturated fatty acids, pharmaceutical compositions containing the provided compounds, and methods of treating a subject with a condition or disease using provided compounds or pharmaceutical compositions.
Type:
Grant
Filed:
April 27, 2020
Date of Patent:
January 2, 2024
Assignees:
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE, UNIVERSITY OF SOUTHERN CALIFORNIA
Abstract: The present invention provides a composition comprising the compound having the structure: or a salt of the compound; 4-amino-2-[19F]-fluorobenzoic acid or a salt of 4-amino-2-[19F]-fluorobenzoic acid; and at least one acceptable carrier.
Type:
Grant
Filed:
September 6, 2017
Date of Patent:
January 2, 2024
Assignee:
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
Inventors:
Peter Tonge, Zhuo Zhang, Peter Smith-Jones, Li Liu, Hui Wang
Abstract: An improved alkaline pretreatment of biomass is provided that is a single-stage, two oxidant alkaline oxidative pretreatment process. The process uses a homogenous catalyst with at least two oxidants (Hydrogen peroxide and enhanced levels of oxygen) in an alkaline environment to catalytically pretreat lignocellulosic biomass in a single-stage oxidation reaction. The provided single-stage alkaline-oxidative pretreatment improves biomass pretreatment and increase enzymatic digestibility to improve the economic feasibility of production of lignocellulose derived sugars.
Type:
Grant
Filed:
August 29, 2022
Date of Patent:
January 2, 2024
Assignees:
Board of Trustees of Michigan State University, Montana State University, Wisconsin Alumni Research Foundation
Inventors:
Eric L. Hegg, Zhaoyang Yuan, David B. Hodge, Shannon S. Stahl, Bryan D. Bals
Abstract: Disclosed herein is a catalyst which comprises a silica core having an outer surface and a mesoporous silica shell having an outer surface and an inner surface with the inner surface being inside the outer surface of said mesoporous silica shell proximate to and surrounding the outer surface of said silica core. Wherein the outer surface of the mesoporous silica shell has openings leading to pores within the mesoporous silica shell which extend toward the outer surface of said silica core. The catalyst also includes catalytically active metal nanoparticles positioned within the pores proximate to said core, wherein the catalytic metal nanoparticles comprise about 0.0001 wt % to about 1.0 wt % of the catalyst. Also disclosed are methods of making the catalyst and using it to carry out a process for catalytically hydrogenolysizing a polyolefinic polymer.
Type:
Grant
Filed:
October 8, 2021
Date of Patent:
January 2, 2024
Assignees:
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC., CORNELL UNIVERSITY
Inventors:
Aaron D. Sadow, Wenyu Huang, Frédéric A. Perras, Marek Pruski, Akalanka Tennakoon, Xun Wu, Anne M. Lapointe
Abstract: Described here are systems and methods for generating and implementing a hybrid machine learning and mechanistic model to produce biological feature maps, or other measurements of biological features, based on an input of multiparametric magnetic resonance or other images. The hybrid model can include a combination of a machine learning model and a mechanistic model that takes as an input multiparametric MRI, or other imaging, data to generate biological feature maps (e.g., tumor cell density maps), or other measures or predictions of biological features (e.g., tumor cell density). The hybrid models have capabilities of learning individual-specific relationships between imaging features and biological features.
Type:
Grant
Filed:
November 19, 2018
Date of Patent:
January 2, 2024
Assignees:
Mayo Foundation for Medical Education and Research, Arizona Board of Regents on behalf of Arizona State University
Inventors:
Leland S. Hu, Jing Li, Kristin R. Swanson, Teresa Wu, Nathan Gaw, Hyunsoo Yoon, Andrea Hawkins-Daarud