Abstract: The present invention relates in part to a lignin composition and a method of fabricating a lignin composition. The invention also relates in part to a method of using a lignin composition to adsorb onto a petrochemical oil comprising the steps of providing a solution of lignin in an alcohol, providing an oil on a liquid surface, contacting the oil with the solution of lignin in an alcohol, adsorbing the lignin to the oil, and removing the adsorbed oil from the surface of the liquid.
Type:
Grant
Filed:
October 3, 2019
Date of Patent:
January 9, 2024
Assignee:
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Abstract: The present invention generally provides methods to generate plants with high frequency of spontaneous haploid genome doubling for use in doubled haploid production. The invention relates to the BUBR1 nucleic acid and protein sequences identified, which are associated with spontaneous haploid genome doubling.
Type:
Grant
Filed:
September 20, 2021
Date of Patent:
January 9, 2024
Assignee:
Iowa State University Research Foundation, Inc.
Inventors:
Thomas Lubberstedt, Ursula Karoline Frei
Abstract: The embodiments herein provide for an oxygen/air cathode that includes metal-organic frameworks and/or hybrids of metal-organic frameworks and carbon networks. The metal-organic-framework-based Li—O2 cells are operated in humid O2 where water plays a critical role in improving battery performance. Such embodiments not only improve battery performance but also reduces the cost by cycling the Li—O2 batteries in humid oxygen with MOF@CNT hybrid catalysts.
Type:
Grant
Filed:
May 17, 2019
Date of Patent:
January 9, 2024
Assignees:
Washington State University, Hyundai Motor Company, Kia Corporation
Inventors:
Min-Kyu Song, Xiahui Zhang, Wonkeun Kim, Ji-hoon Jang
Abstract: A physical unclonable functions (PUF) device including a first copper electrode, a second electrode, and a silicon oxide layer positioned directly between the first copper electrode and the second electrode; a method of producing a PUF device; an array comprising a PUF device; and a method of generating a secure key with a plurality of PUF devices.
Type:
Grant
Filed:
September 21, 2021
Date of Patent:
January 9, 2024
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: The disclosure relates to textile biosensors and related systems that can be used for in situ health monitoring and disease detection. The biosensors include a flexible or textile substrate, a working electrode embroidered thereon, a reference electrode embroidered thereon, optionally a counter electrode embroidered thereon, and an enzyme probe bound to the working electrode. The biosensors can be integrated directly onto fabrics and garments to provide lightweight, unobtrusive wearable sensing systems that do not compromise wearer mobility, comfort or attention.
Type:
Grant
Filed:
April 28, 2017
Date of Patent:
January 9, 2024
Assignee:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Abstract: A method of modelling data, comprising: training an objective function of a linear classifier, based on a set of labeled data, to derive a set of classifier weights; defining a posterior probability distribution on the set of classifier weights of the linear classifier; approximating a marginalized loss function for an autoencoder as a Bregman divergence, based on the posterior probability distribution on the set of classifier weights learned from the linear classifier; and classifying unlabeled data using the autoencoder according to the marginalized loss function.
Type:
Grant
Filed:
December 19, 2021
Date of Patent:
January 9, 2024
Assignee:
The Research Foundation for The State University of New York
Abstract: Methods of using fiber-reinforced composite articles useful in supporting or immobilizing an injured body part is disclosed. The composite is a multi-layer, flexible precursor including fiber reinforcement plies, which can be rapidly cured into a rigid body using a thermosetting resin. Methods of making and using the same are also disclosed, along with kits containing such composite articles.
Type:
Grant
Filed:
March 18, 2022
Date of Patent:
January 9, 2024
Assignee:
Wichita State University
Inventors:
John S. Tomblin, Thomas Aldag, William T. McCarvill, Kimberly M. Reuter, Joel D. White, Andrea C. Meyer
Abstract: Disclosed is a modular, portable and rapidly deployable system for health assessment comprising a portable, rapidly deployable structure configured to provide immediate and real-time clinical prevention assessment services, which system allows for rapid assembly and disassembly, immediate deployment to even highly remote locations, and provides basic clinical prevention data and screening for a patient user, along with health education and awareness. In certain configurations, the system comprises modular walls that connect to one another to form the shell of a structure, and a plurality of medical instruments, all of which are configured for self-administration by a medically-untrained user. The user may engage one or more user interface devices that guide the user through the use of each medical instrument and collect the user's clinical data for analysis.
Abstract: Described herein are in situ synthesized arrays and methods of making the them, wherein array signal sensitivity and robustness is enhanced by carrying out conditioning steps and/or generating linkers during synthesis. An array comprises a surface with a collection of features, wherein the features comprise molecules or polymers attached to the surface. In certain embodiments of the invention, carrying out conditioning steps during array synthesis can yield arrays with improved signal. In other embodiments, linkers are synthesized on the array surface prior to synthesis of functional molecules, wherein increasing linker length can correspond to an improvement in the signal generated by the array.
Type:
Grant
Filed:
August 31, 2020
Date of Patent:
January 9, 2024
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: Methods and systems are provided for serial femtosecond crystallography for reducing the vast amount of waste of injected crystals practiced with traditional continuous flow injections. A micrometer-scale 3-D printed water-in-oil droplet generator device includes an oil phase inlet channel, an aqueous phase inlet channel, a droplet flow outlet channel, and two embedded non-contact electrodes. The inlet and outlet channels are connected internally at a junction. The electrodes comprise gallium metal injected within the 3-D printed device. Voltage across the electrodes generates water-in-oil droplets, determines a rate for a series of droplets, or triggers a phase shift in the droplets. An external trigger generates the droplets based on the frequency of an XFEL utilized in droplet detection, thereby synchronizing a series of droplets with x-ray pulses for efficient crystal detection. The generated droplets can be coupled to an SFX with XFEL experiment compatible with common liquid injector such as a GDVN.
Type:
Grant
Filed:
April 1, 2021
Date of Patent:
January 9, 2024
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Inventors:
Alexandra Ros, Daihyun Kim, Austin Echelmeier, Jorvani Cruz Villarreal, Ana Egatz-Gomez, Sebastian Quintana
Abstract: Provided herein are small molecule compounds, including non-anticoagulant heparan sulfate oligosaccharide molecules, having anti-inflammatory properties and capable of interacting with high mobility group box 1 (HMGB1) proteins in a manner sufficient to affect an interaction between the HMGB1 protein and a receptor for advanced glycation end products (RAGE). Also provided herein are methods of treating Paracetamol (APAP) overdose in subjects.
Type:
Grant
Filed:
November 5, 2018
Date of Patent:
January 9, 2024
Assignees:
The University of North Carolina at Chapel Hill, The Research Foundation for the State University of New York
Abstract: A metamaterial comprising, a plurality of acoustic vector field sensors, each configured to sense an acoustic vector field of a fluid within a fluid-filled space in response to fluid waves, and producing an electrical signal corresponding to the sensed acoustic vector field; a processor configured to perform a time and space transform on the electrical signal; and at least one phased array transducer, configured to emit fluid waves according to a produced acoustic vector field pattern dependent on a result of the time and space transform, a within a portion of the fluid.
Type:
Grant
Filed:
April 19, 2022
Date of Patent:
January 9, 2024
Assignee:
The Research Foundation for The State University of New York
Abstract: A method, system, and device for managing off-grid power supply are provided. The method includes acquiring data from one or more loads. The one or more loads are connected to the off-grid power supply. The method further includes modeling the one or more loads based on the acquired data, estimating a state of charge of an energy storage device (ESD) associated with the off-grid power supply, and determining an operational status of each of the one or more loads. The operational status is based on at least the state of charge of the ESD and a category of each of the one or more loads. Each load is controlled based on the operational status.
Type:
Grant
Filed:
March 16, 2018
Date of Patent:
January 9, 2024
Assignees:
TOTAL SOLAR INTERNATIONAL, NORTH CAROLINA STATE UNIVERSITY
Inventors:
Wente Zeng, Jiahong Yan, Ning Lu, Fuhong Xie
Abstract: The present disclosure relates to support structures for three dimensional (3D) printing, methods of preparing the support structures, and methods of using the support structures. In particular, the support structures comprise a hydrogel comprised of a cellulose derivative. Preferably, the support structures are biodegradable and easily removed without generating toxic waste.
Type:
Grant
Filed:
April 12, 2021
Date of Patent:
January 9, 2024
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: The disclosure relates to vaccination compositions, for example, against human papillomavirus, Zika virus, and flu virus. The disclosure also relates to vectors for producing the virus-like particles and immune complex platforms of the vaccination compositions.
Type:
Grant
Filed:
July 2, 2021
Date of Patent:
January 9, 2024
Assignee:
Arizona Board of Regents on Behalf of Arizona State University
Inventors:
Hugh Mason, Andrew Diamos, Mary Pardhe, Brandon Favre
Abstract: A hybrid shellfish cooling system employs DC and AC cooling units using both solar power and AC electrical supply as energy sources. As temperature control and uniform temperature distribution in the cooling system are critical factors in reducing vibrio growth on raw oysters and reducing energy consumption, the system is equipped with a divider that optimizes airflow through the cooling system interior cabinet to achieve uniform temperature distribution in six individual internal compartments. Tests indicated that an average of 130 min. cooling was required to reach the suggested oyster temperatures of 7.2° C. and meet the cooling time requirement (i.e., 10 h or less). Airflow is further optimized via fan location and airflow direction, whereby configuration of a circulation fan on a lower part of the 12-volt DC section with an air supply from the 12-volt DC section to the 110-volt AC section achieves relatively uniform temperature distribution.
Abstract: The present invention is toward a base oil or lubricant additives, methods of using the same, lubricant compositions including the same, and methods of forming the lubricant compositions. A base oil or lubricant additive has Structure I or Structure II as described herein.
Type:
Grant
Filed:
November 23, 2022
Date of Patent:
January 9, 2024
Assignee:
Iowa State University Research Foundation, Inc.
Inventors:
George A. Kraus, Kyle Podolak, Derek Lee White, Sriram Sundararajan
Abstract: A single-chain variable fragment (ScFv) derived from anti-c-Met monoclonal antibody MetMAb that specifically binds to c-Met receptor is provided. Also provided are chimeric antigen receptor (CAR) vectors including the ScFv, human T cells transduced with the disclosed CAR vectors, pharmaceutical compositions including the CAR T cells, ScFv fusion proteins, and methods of treating a c-Met-positive cancer or a cancer characterized by overexpression of c-Met in a subject in need thereof by administering an effective amount of the disclosed CAR T cells.
Type:
Grant
Filed:
November 2, 2020
Date of Patent:
January 9, 2024
Assignee:
EAST TENNESSEE STATE UNIVERSITY RESEARCH FOUNDATION
Abstract: This invention relates to vectors for delivery of human leukocyte antigen G to the eye and/or to cornea explants and methods of using the same for treatment and/or prevention of corneal transplant rejection and other disorders associated with an immune response and/or vascularization.
Type:
Grant
Filed:
July 26, 2017
Date of Patent:
January 9, 2024
Assignees:
The University of North Carolina at Chapel Hill, North Carolina State University
Inventors:
Matthew Louis Hirsch, Brian Christopher Gilger
Abstract: An auscultation system comprises an auscultation device comprising a wearable apparatus positionable proximate to a lung, a plurality of audio sensors embedded in the wearable apparatus configured to record lung sounds, wherein the plurality of audio sensors are positioned at locations of the wearable apparatus corresponding to lung auscultation points, and a computing system communicatively connected to the auscultation device, comprising a processor and a non-transitory computer-readable medium with instructions stored thereon, which when executed by a processor, perform steps comprising, establishing a background noise spectrum, recording a lung sound spectrum via the auscultation device for a period of time, calculating a background subtracted lung sound spectrum by subtracting the background noise spectrum from the measured lung sound spectrum, analyzing the background subtracted lung sound spectrum to produce an auscultation result, and providing the auscultation result to a practitioner to assist in pr
Type:
Application
Filed:
June 29, 2023
Publication date:
January 4, 2024
Applicant:
Arizona Board of Regents on behalf of Arizona State University