Patents Assigned to STC.UNM
  • Composite metal and bone orthopedic fixation devices
    Patent number: 9173692
    Abstract: Composite orthopedic devices that facilitate spine stabilization, such as: bone screws, rods, plates, interbodies, and corpectomy cages are disclosed. They are designed to provide both strength and load carrying capabilities, while increasing bio-integration of the devices with the surrounding bone tissue. They are constructed of composite layers of allograft and/or autograft bone and a structural material, such as titanium alloy or carbon/graphite fiber composite. Cannulations within the device are loaded with a mixture of stem cells, particles of allograft and/or autograft bone, and bone growth factors, such as BMP-2. The cannulations are connected to the surface of the device via multiple fenestrations that provide pathways to supply the bone/stem cell mixture to the surface, allowing living bone tissue to grow and insure bio-integration.
    Type: Grant
    Filed: June 15, 2013
    Date of Patent: November 3, 2015
    Assignee: STC.UNM
    Inventor: Paul E. Kaloostian
  • CATHODE CATALYSTS FOR FUEL CELL APPLICATION DERIVED FROM POLYMER PRECURSORS
    Publication number: 20150295248
    Abstract: A method of preparing M-N-C catalysts utilizing a sacrificial support approach and inexpensive and readily available polymer precursors as the source of nitrogen and carbon is disclosed. Exemplary polymer precursors include those that do not form complexes with iron, but which do complex with silica, for example, polyetheleneimine (PEI), Poly(2-ethyl-2-oxazoline), Poly(acrylamide-co-diallyldimethylammonium chloride), Poly(melamine-co-formaldehyde), Poly[[6-[(1,1,3,3-tetramethylbutyl)amino]-s-triazine-2,4-diyl]-[(2,2,6,6-tetramethyl-4-piperidyl)imino]-hexamethylene-[(2,2,6,6-tetramethyl-4-piperidyl)imino] and the like.
    Type: Application
    Filed: June 15, 2012
    Publication date: October 15, 2015
    Applicant: STC.UNM
    Inventors: Alexey Serov, Barr Halevi, Michael Robson, Wendy Patterson, Kateryna Artyushkova, Plamen B. Atanassov
  • Pliable Pressure-Sensing Fabric
    Publication number: 20150292964
    Abstract: A pliable pressure sensitive sensor device and method of making the same is provided. The sensor includes first and second pliable protective layers, which cover sets of conductive fibers that spatially separated by an electrically conductive pliable layer, which deforms in response to a pressure event. The fiber sets form a grid pattern and are in electrical communication with sets of electrical contacts located in predetermined locations along the fibers. In response to a pressure event in proximity to the contact, the pliable layer deforms and increases the amount of surface area in contact with an electrical contact whereby an electrical resistance at an individual electrical contact decreases in response to the pressure event.
    Type: Application
    Filed: October 7, 2013
    Publication date: October 15, 2015
    Applicant: STC.UNM
    Inventor: Scott Sibbett
  • Fabrication of enclosed nanochannels using silica nanoparticles
    Patent number: 9156004
    Abstract: In accordance with the invention, there is a method of forming a nanochannel including depositing a photosensitive film stack over a substrate and forming a pattern on the film stack using interferometric lithography. The method can further include depositing a plurality of silica nanoparticles to form a structure over the pattern and removing the pattern while retaining the structure formed by the plurality of silica nanoparticles, wherein the structure comprises an enclosed nanochannel.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: October 13, 2015
    Assignee: STC.UNM
    Inventors: Steven R. J. Brueck, Deying Xia, Yuliya Kuznetsova, Alexander Neumann
  • Compact biosensor of matrix metalloproteinase with cadmium free quantum dots
    Patent number: 9155497
    Abstract: The invention provides a quantum dot (QD) modified optical fiber-based biosensor which characterizes matrix metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS) in vivo. Related systems and peptide biomarker screening methods are also provided.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: October 13, 2015
    Assignee: STC.UNM
    Inventors: John B. Plumley, Erin D. Milligan, Marek Osinski
  • Method and apparatus for fabrication of large area 3D photonic crystals with embedded waveguides
    Patent number: 9152040
    Abstract: In accordance with some aspects of the present disclosure, a maskless interferomeric lithography system for fabricating a three-dimensional (3D) photonic crystal using a multiple two-beam-exposures is disclosed. The system can comprise an illumination system comprising an optical arrangement operable to receive radiation from a radiation source and provide three or more tilted two-beam interference pattern exposures to be combined into a three-dimensional pattern; and a substrate operable to be supported by a substrate table, wherein the substrate comprises a photoresist formed on a top surface of the substrate and operable to receive the three-dimensional pattern and wherein means are provided to adjust the position of the substrate in all six mechanical degrees of freedom.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: October 6, 2015
    Assignee: STC.UNM
    Inventors: Steven R. J. Brueck, Alexander K. Raub
  • Cubic phase, nitrogen-based compound semiconductor films
    Patent number: 9153431
    Abstract: A method of epitaxially growing nitrogen-based compound semiconductor thin films on a semiconductor substrate, which is periodically patterned with grooves. The method can provide an epitaxial growth of a first crystalline phase epitaxial film on the substrate, and block the growth of an initial crystalline phase with barrier materials prepared at the sides of the grooves. Semiconductor devices employing the epitaxial films are also disclosed.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: October 6, 2015
    Assignee: STC.UNM
    Inventors: Seung-Chang Lee, Steven R. J. Brueck
  • Method of making magnetic iron nitride nanoparticles
    Patent number: 9153367
    Abstract: Magnetic iron nitride nanoparticles, such as Fe16N2 nanoparticles, are made by subjecting iron nanoparticles synthesized from iron oxide or iron carbonyl precursor to a solid-gas reaction with a nitrogen-containing gas.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: October 6, 2015
    Assignee: STC.UNM
    Inventor: Leisha M. Armijo
  • SYSTEM AND METHODS FOR SIMULATING REAL-TIME MULTISENSORY OUTPUT
    Publication number: 20150268926
    Abstract: The invention is directed to a system and methods allowing a user to interact with one or more data applications—including for example, games, music, music composition and tactile stimulation—to simulate real-time multisensory output. The invention includes a music program, a music texture program and a simulation program.
    Type: Application
    Filed: October 8, 2013
    Publication date: September 24, 2015
    Applicant: STC. UNM
    Inventor: Panaiotis -
  • Method of making a heteroepitaxial layer on a seed area
    Patent number: 9142400
    Abstract: A method for making a heteroepitaxial layer. The method comprises providing a semiconductor substrate. A seed area delineated with a selective growth mask is formed on the semiconductor substrate. The seed area comprises a first material and has a linear surface dimension of less than 100 nm. A heteroepitaxial layer is grown on the seed area, the heteroepitaxial layer comprising a second material that is different from the first material. Devices made by the method are also disclosed.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: September 22, 2015
    Assignee: STC.UNM
    Inventors: Steven R. J. Brueck, Stephen D. Hersee, Seung-Chang Lee, Daniel Feezell
  • Non-PGM Catalyst for Orr Based on Pyrolysed Poly-Complexes
    Publication number: 20150263353
    Abstract: Novel catalytic materials and novel methods of preparing M—N—C catalytic materials utilizing a sacrificial support approach and using inexpensive active polymers as the carbon and nitrogen source and readily available metal precursors are described.
    Type: Application
    Filed: October 15, 2013
    Publication date: September 17, 2015
    Applicant: STC.UNM
    Inventors: Alexey SEROV, Plamen b. ATANASSOV, Barr HALEVI, Paul SHORT
  • ROTATION-SENSITIVE SEMICONDUCTOR RING LASER DEVICE USING THE NONLINEAR SAGNAC EFFECT
    Publication number: 20150260521
    Abstract: Method and apparatus embody a rotation sensor including one or more ring lasers designed to utilize a nonlinear Sagnac effect, a passive waveguide arrangement, and a photodetector arrangement to receive the outcoupled light and to detect rotation of the sensor; wherein these components are arranged into a monolithically integrated optoelectronic integrated circuit on a single substrate. The method and apparatus can include seeding a stable, rotation-insensitive, strong (driving) wave using a single-frequency edge emitting laser monolithically integrated on the same substrate.
    Type: Application
    Filed: September 16, 2013
    Publication date: September 17, 2015
    Applicant: STC.UNM
    Inventors: Marek A. Osinski, Petr G. Eliseev, Edward W. Taylor
  • Targeting abnormal DNA repair in therapy-resistant breast and pancreatic cancers
    Patent number: 9132120
    Abstract: In one embodiment, the invention provides a method of treating a subject suffering from a breast cancer tumor which is non-responsive or intrinsically resistant to anti-estrogen therapy comprising administering a therapeutically effective amount of an inhibitor of alternative (ALT) non-homologous end joining (NHEJ) factor to the subject. In another embodiment the invention provides a method of treating a subject who suffers from a pancreatic cancer which is non-responsive to chemotherapy and/or radiation comprising co-administering a therapeutically effective amount of PARP1 inhibitor and a DNA ligase III? inhibitor to the subject. Related diagnostic methods, nucleic acid arrays, devices and kits are also provided.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: September 15, 2015
    Assignees: STC.UNM, UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Alan Edward Tomkinson, Feyruz Rassool
  • STEP-Derived Peptide for Brain Injury Treatment
    Publication number: 20150252339
    Abstract: A novel peptide sequence that is a modified derivative of a neuron-specific tyrosine phosphatase is shown and described. Specifically, the novel peptide sequence is a modified derivative of striatal-enriched tyrosine phosphatase (STEP). The peptide sequence has been modified so as to be able to ameliorate and treat brain injury resulting from excessive glutamate release and/or oxidative stress. Examples of the types of brain injury which the presently disclosed peptide sequence is useful for treating includes acute brain injury resulting from stroke or traumatic brain injury and chronic disorders such as Huntington's chorea and schizophrenia. Furthermore, the presently described peptide sequence may further be useful in the treatment and amelioration of disorders associated with fear memory such as post-traumatic stress disorder.
    Type: Application
    Filed: May 26, 2015
    Publication date: September 10, 2015
    Applicant: STC.UNM
    Inventor: Surojit Paul
  • Thiophene based oligomers as light activated biocides
    Patent number: 9125415
    Abstract: Thiophene containing water-soluble oligomers were synthesized and characterized. The photophysical properties of these compounds were studied; transient absorption spectroscopy was used to probe the triplet excited state and their ability to sensitize singlet oxygen was spectroscopically monitored in deuterated methanol. The above compounds were tested for their light activated biocidal properties against S. aureus both under UV and visible radiation. Among the oligomers studied, the terthiophene derivative was found to kill the bacteria efficiently.
    Type: Grant
    Filed: July 5, 2012
    Date of Patent: September 8, 2015
    Assignees: STC, UNM, University of Florida Research Foundation, Inc.
    Inventors: Kirk S. Schanze, Anand Parthasarathy, Subhadip Goswami, David G. Whitten, Eunkyung Ji, Thomas S. Corbitt, Dimitri Dascier
  • Modulators of GTPases and their use
    Patent number: 9125899
    Abstract: The present invention relates to molecules which function as modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases (e.g. Rac, Cdc42 and Rho GTPases) and their use to treat diseases, including cancers (including solid tumors-medulloblastoma, ovarian, breast, head and neck, testicular, prostate among others and hematologic malignancies-B cell lymphoma, where these GTPases are overexpressed or hyperactivated), sporadic and genetic diseases where activation of Rho GTPases plays a pivotal role (Menkes disease, rheumatoid arthritis, atherosclerosis, diabetes (type 1), Huntington's disease and Alzheimer's disease) which are mediated through these proteins. Compounds according to the present invention may also be used as a therapy for the treatment of Entamoeba spp. or Acanthamoeba spp, infections, especially including Entamoeba histolytica.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: September 8, 2015
    Assignee: STC.UNM
    Inventors: Angela-Wandinger Ness, Laurie Hudson, Larry Sklar, Zurab Surviladze, Tudor Oprea
  • Thermal neutron detectors based on gadolinium-containing nanoscintillators
    Patent number: 9116246
    Abstract: A thermal neutron detector and method employ Gd-containing nanoscintillators. Thermal neutron radiation is detected by observing scintillation events from the nanoscintillators.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: August 25, 2015
    Assignee: STC.UNM
    Inventors: Marek A. Osinski, Brian A. Akins, John B. Plumley, Antonio C. Rivera, Gennady A. Smolyakov, Jose M. Vargas, Nathan J. Withers
  • System and methods for improved real time functional magnetic resonance imaging
    Patent number: 9116219
    Abstract: A system and methods for high-speed functional magnetic resonance imaging using multi-slab echo-volumar imaging (EVI), specifically a combination of multi-slab excitation and single-shot 3D encoding with parallel imaging to reduce geometrical image distortion and blurring, and to increase blood oxygenation level-dependent (BOLD) sensitivity compared to conventional echo-planar imaging (EPI).
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: August 25, 2015
    Assignee: STC.UNM
    Inventor: Stefan Posse
  • System and methods for dynamic management of hardware resources
    Patent number: 9111059
    Abstract: A dynamically reconfigurable framework manages processing applications in order to meet time-varying constraints to select an optimal hardware architecture. The optimal architecture satisfies time-varying constraints including for example, supplied power, required performance, accuracy levels, available bandwidth, and quality of output such as image reconstruction. The process of determining an optimal solution is defined in terms of multi-objective optimization using Pareto-optimal realizations.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: August 18, 2015
    Assignee: STC.UNM
    Inventors: Marios Stephanou Pattichis, Yuebing Jiang, Daniel Rolando Llamocca Obregon
  • Carbendazim-Based Catalytic Materials
    Publication number: 20150228985
    Abstract: A method of preparation of M-N—C catalytic material utilizing a sacrificial support approach and using inexpensive and readily available metal precursors and carbendazim (CBDZ) as the carbon source is described.
    Type: Application
    Filed: July 11, 2013
    Publication date: August 13, 2015
    Applicant: STC.UNM
    Inventors: Alexey Serov, Plamen B Atanassov