Patents Assigned to Stiefel Laboratories, Inc.
  • Patent number: 4393061
    Abstract: N-[3-(4-{3-Fluorobenzyloxy}phenoxy)propyl]morpholine and its pharmaceutically acceptable salts possess topical anesthetic-antipruritic properties. The free base can be obtained by coupling an alkali metal salt of 4-(3-fluorobenzyloxy)phenol and N-(3-chloropropyl)morpholine.
    Type: Grant
    Filed: June 21, 1982
    Date of Patent: July 12, 1983
    Assignee: Stiefel Laboratories, Inc.
    Inventor: Cheng-Sein Yu
  • Patent number: 4056611
    Abstract: The therapeutic composition is for the treatment of acne and comprises a stable dispersion of finely divided particles of benzoyl peroxide in an aqueous alcohol vehicle having a single phase, said phase being non-lipid and containing a non-ionic surface active agent that is soluble in the aqueous alcohol vehicle of the composition. The composition comprises from about 1 to 30 percent by weight benzoyl peroxide, from about 1 to 30 percent by weight of said surface active agent, from about 10 to 80 percent by weight of an alkyl alcohol having from 1 to 3 carbon atoms, and from about 10 to 80 percent by weight of water. The hydrophilic portion of the surface active agent is a polyoxyalkylene moiety wherein each oxyalkylene group contains from 2 to 3 atoms, and preferably is polyoxyethylene lauryl ether.
    Type: Grant
    Filed: April 16, 1973
    Date of Patent: November 1, 1977
    Assignee: Stiefel Laboratories, Inc.
    Inventor: Henry Y. Young
  • Patent number: 4036991
    Abstract: A composition that may be used as the base vehicle for cosmetic or therapeutic preparations that are applied to the human skin contains as one of the essential constituents thereof at least one member of the group consisting of cis-6-hexadecenoic acid and the glycerol, glycol and monohydric alcohol esters of cis-6-hexadecenoic acid.
    Type: Grant
    Filed: January 24, 1972
    Date of Patent: July 19, 1977
    Assignee: Stiefel Laboratories, Inc.
    Inventor: Werner K. Stiefel
  • Patent number: 3959491
    Abstract: A cosmetic composition for topical application to human skin comprises from 40 to 80 percent by weight sterilized fluid milk containing from about 7 to 18 percent fat and from about 8 to 11 percent non-fat solids, from 1 to 5 percent by weight of at least one fatty acid (for example, stearic acid), from 2.5 to 10 percent by weight of at least one triglyceride ester of a saturated fatty acid (for example, glycerol monostearate), from 5 to 15 percent by weight of at least one alkyl ester of a saturated fatty acid (for example, isopropyl palmitate), from 5 to 15 percent by weight of at least one alkane diol (for example, propylene glycol), from 0.1 to 0.5 percent by weight a salt of ethylenediamine tetraacetic acid (for example, disodium ethylenediamine tetraacetate dihydrate), from 0.1 to 0.5 percent by weight sorbic acid, from 0.3 to 0.5 percent by weight 1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadomantane chloride, and the balance essentially water.
    Type: Grant
    Filed: October 29, 1974
    Date of Patent: May 25, 1976
    Assignee: Stiefel Laboratories, Inc.
    Inventors: Henry Y. Young, Edward Henderson, deceased