Abstract: The present invention refers to a process for transition-metal-assisted 18F-deoxyfluorination of phenols. The transformation benefits from readily available phenols as starting materials, tolerance of moisture and ambient atmosphere, large substrate scope, and translatability to generate doses appropriate for positron emission tomography (PET) imaging.
Type:
Application
Filed:
July 10, 2018
Publication date:
November 26, 2020
Applicants:
STUDIENGESELLSCHAFT KOHLE MBH, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Inventors:
Tobias RITTER, Constanze NEUMANN, Mohammad Hassan BEYZAVI, Martin Georg STREBL-BANTILLO, Debashis MANDAL
Abstract: The present invention refers to a process for a transition metal, particularly nickel-catalyzed cyanation reaction of aryl/vinyl halide using organic nitrile compounds. This new reaction provides a strategically distinct approach to the safe preparation of aryl/vinyl cyanides, which are essential compounds in agrochemistry and medicinal chemistry.
Abstract: The present invention refers to a process for a Rh-catalyzed Anti-Markovnikov hydrocyanation of terminal alkynes which process discloses, for the first time, the highly stereo- and regio-selective hydrocyanation of terminal alkynes to furnish E-configured alkenyl nitriles and the catalyst used in the present process.
Abstract: The present invention refers to processes for catalytic reversible alkene-nitrile interconversion through controllable HCN-free transfer hydrocyanation.
Abstract: The present application refers to a process for preparing of nanostructured metal oxides such as cobalt oxide and transition metal incorporated cobalt oxides and nickel aluminium oxides and nickel metal supported on aluminium oxide using plant material such as spent tea leaves as a hard template and the use of such catalysts for water oxidation.
Abstract: Provided herein are palladium complexes comprising a ligand of Formula (A?) and a ligand of Formula (B), wherein R1-R18 are as defined herein. The palladium complexes are useful in methods of fluorinating aryl and heteroaryl substrates. Further provided are compositions and kits comprising the palladium complexes.
Type:
Application
Filed:
March 9, 2017
Publication date:
April 4, 2019
Applicants:
President and Fellows of Harvard College, Studiengesellschaft Kohle mbH
Abstract: The present invention refers to a process for removing Cs, and optionally Rb, from aqueous fluids including body fluids by fluorine containing reagents, the synthesis of fluorine containing, water-insoluble salts of said Cs isotopes and their use as therapeutic agents.
Abstract: The present invention refers to processes for catalytic reversible alkene-nitrile interconversion through controllable HCN-free transfer hydrocyanation.
Abstract: The present invention refers to a process for preparing amines comprising reacting a compound of the formula R1—CO—R2 comprising a carbonyl moiety with a amine compound of the formula HNR3R4 and carbon monoxide in the presence of a catalyst.
Type:
Grant
Filed:
December 10, 2013
Date of Patent:
January 1, 2019
Assignee:
STUDIENGESELLSCHAFT KOHLE MBH
Inventors:
Benjamin List, Denis Alexandrovich Chusov
Abstract: The present invention refers to a process making use of a radical initiator system comprising peroxy compounds, in particular peroxyketals, in the presence of an acid catalyst to initiate radical processes at low temperature, such as room temperature and below.
Type:
Application
Filed:
December 20, 2016
Publication date:
December 27, 2018
Applicants:
STUDIENGESELLSCHAFT KOHLE MBH, HASSELT UNIVERSITY
Inventors:
Martin KLUSSMANN, Joke VANDENBERGH, Thomas JUNKERS, Bertrand SCHWEITZER-CHAPUT
Abstract: The present invention relates to chiral phosphoramidimidates, their salts and metal complexes as well as derivatives thereof and their use as catalysts.
Type:
Application
Filed:
August 31, 2016
Publication date:
November 29, 2018
Applicant:
STUDIENGESELLSCHAFT KOHLE MBH
Inventors:
Benjamin LIST, Philip Stephan Joseph KAIB, Lucas SCHREYER, Sunggi LEE, Roberta PROPERZI, Luping LIU
Abstract: Surfactants of the general formula (I) in which R1 is a linear or branched akyl radical having 6 to 20, especially 10 to 16 C atoms, R2 and R3 independently of one another are H or H3CO, and M is hydrogen, an alkali metal or a moiety N+R4R5R6, in which R4, R5 and R6 independently of one another are hydrogen, an alkyl group having 1 to 6 C atoms or a hydroxyalkyl group having 2 to 6 C atoms, are readily incorporated into laundry detergents or cleaning products, possess outstanding performance qualities and can be prepared on the basis of renewable raw materials.
Type:
Application
Filed:
February 2, 2018
Publication date:
June 7, 2018
Applicants:
Henkel AG & Co. KGaA, Studiengesellschaft Kohle mbH
Inventors:
Christian Kropf, Alexander Schulz, Hendrik Hellmuth, Roberto Rinaldi, Hebert Jesus Estevez Rivera
Abstract: Surfactants of general formula (I), in which R1 denotes a linear or branched alkyl residue having 6 to 20, and in particular 8 to 14 carbon atoms, R2 denotes H or CH3, and M denotes hydrogen, an alkali metal or an N+R3R4R5 grouping, in which R3, R4 and R5, independently of one another, denote hydrogen, an alkyl group having 1 to 6 carbon atoms or a hydroxyalkyl group having 2 to 6 carbon atom, can be easily incorporated into washing or cleaning agents, have outstanding application-related properties, and can be produced based on renewable resources.
Type:
Application
Filed:
February 2, 2018
Publication date:
June 7, 2018
Applicants:
Henkel AG & Co. KGaA, Studiengesellschaft Kohle mbH
Inventors:
Christian Kropf, Alexander Schulz, Hendrik Hellmuth, Roberto Rinaldi, Hebert Jesus Estevez Rivera
Abstract: The present invention deals with the synthesis and applications of new cationic compounds being useful as metal ligands. Specifically, N-alkyl/aryl substituted pyridiniophosphines are prepared and used as ligands for transition metals. The so-obtained metal complexes and their use as catalysts in chemical synthesis is also described. It also worth mentioning that N-alkyl/aryl pyridiniophosphines can be synthesized through a short, scalable and highly modular route.
Type:
Grant
Filed:
April 21, 2015
Date of Patent:
May 8, 2018
Assignee:
STUDIENGESELLSCHAFT KOHLE MBH
Inventors:
Manuel Alcarazo, Christian Wille, Hendrik Tinnermann
Abstract: The present invention relates to a process for the asymmetric oxidation of nucleophilic organic compounds, particularly metal-free, with peroxide compounds in the presence of a chiral Brønsted acid catalyst. In one detail, the present invention relates to a process for enantioselective sulfoxidation of thiocompounds with peroxide compounds in the presence of a chiral imidodiphosphate catalyst. In another detail, the present invention relates to a process for enantioselective sulfoxidation of thiocompounds with peroxide compounds in the presence of a chiral phosphoric acid catalyst.
Abstract: The present invention refers to a process for catalytic fractionation of peat, coir, peat-like materials or mosses into a non-pyrolytic bio-oil and a sterile solid fraction with similar volume and structural function to the starting material. The inventive process is useful for a variety of interesting applications, starting from raw peat with a water content of up to 80% resulting in a an oil, rich in polyols and aliphatic molecules.
Abstract: The present invention refers to processes for preparing catalyst loaded polyphenylene particles, the so-obtained polyphenylene particles and their use as catalysts.
Type:
Grant
Filed:
March 24, 2015
Date of Patent:
December 19, 2017
Assignee:
STUDIENGESELLSCHAFT KOHLE MBH
Inventors:
Ferdi Schueth, Alois Fürstner, Feng Wang
Abstract: The present invention refers to a process for the trans-selective hydroboration of internal alkynes and the so-obtained products. The inventive process makes use of a borane of the formula X1X2BH selected from the group of dialkyl boranes or di(alkoxy)boranes which are reacted with the internal alkynes in the presence of a cyclyopentadienyl-coordinated ruthenium catalyst.