Patents Assigned to Surface Technologies, Inc.
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Patent number: 9833543Abstract: Inventive concepts relate general to the field of implantable three-dimensional scaffolds. More particularly, methods of preparing and using implantable nanofibrous tissue scaffolds are described. Inventive scaffolds can be used for treatment of defects in a living organism, such as hard or soft tissue defects including bone.Type: GrantFiled: October 11, 2012Date of Patent: December 5, 2017Assignee: INNOVATIVE SURFACE TECHNOLOGIES, INC.Inventors: Jie Wen, Nell Herrera Wirth, Patrick E Guire
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Patent number: 9814805Abstract: The present disclosure relates to multilayer coatings that include a hydrophobic encasing layer and allow controlled release of a water soluble drug. The encasing layer encases water soluble, or hydrophilic, drugs with a flexible layer and comes in good intimate contact with the water soluble drug layer. Thus, the encasing layer conforms to the water soluble drug and can control the release of the drug. Advantageously, major cuts or fissures in the coating do not cause the water soluble drug to leak or burst out; rather, the encasing layer continues to provide modulated release of the drug. The present disclosure also includes methods of making the multilayer coatings, methods of using the multilayer coatings, and articles that include the multilayer coatings.Type: GrantFiled: April 25, 2014Date of Patent: November 14, 2017Assignee: INNOVATIVE SURFACE TECHNOLOGIES, INC.Inventors: Kristin Taton, Lawin Laurie, Patrick Guire
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Patent number: 9809713Abstract: The invention describes novel compositions of crosslinkers that include at least two pendent photoactivatable groups, such as benzophenone moieties, and an initiator, such as acetophenone.Type: GrantFiled: September 3, 2009Date of Patent: November 7, 2017Assignee: INNOVATION SURFACE TECHNOLOGIES, INC.Inventors: Timothy A. Bloomquist, Mark W. Josephson, Laurie R. Lawin, Kristin S. Taton, Jie Wen
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Patent number: 9539371Abstract: The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied.Type: GrantFiled: June 25, 2015Date of Patent: January 10, 2017Assignee: INNOVATIVE SURFACE TECHNOLOGIES, INC.Inventors: Jie Wen, Kristin Taton, Laurie Lawin, William Knopke, Eric Guire, Patrick Guire
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Patent number: 9464363Abstract: A method for repairing a blade forming a cathode and having a surface to be coated defining a critical area, utilizing an anode, an electrolyte bath including insoluble particles, and a mounting on which the blade is mounted in a working position relative to a reference wall. The mounting is placed in the bath, and the particles and the metal of the anode are co-deposited to form the coating on the surface to be coated. The anode is typically placed facing the critical area and the mounting includes a mechanism for monitoring current lines to obtain a coating with a relatively constant, predetermined thickness for the critical area, that gradually falls to a value of substantially zero along edges of the coating.Type: GrantFiled: December 28, 2010Date of Patent: October 11, 2016Assignees: SNECMA, PRAXAIR SURFACE TECHNOLOGIES INC.Inventors: Justine Menuey, Frederic Braillard, John Foster, Stephen Owens, Alan Taylor, Martin Chatterney
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Publication number: 20160251646Abstract: Inventive concepts relate generally to nanofibrous scaffolds useful for electrophysiological assays. Scaffolds include polymeric nanofibrous components and electrically excitable cells immobilized at a distinct cell seeding domains on the scaffold. Methods and kits including the scaffolds are also described.Type: ApplicationFiled: October 11, 2014Publication date: September 1, 2016Applicant: Innovative Surface Technologies, Inc.Inventors: Eric Guire, Christopher Bahr
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Patent number: 9116144Abstract: A stimuli responsive nanofiber that includes a stimuli responsive polymer, such as a thermally responsive polymer, and a cross-linking agent having at least two latent reactive activatable groups. The nanofiber may also include a biologically active material or a functional polymer. The stimuli responsive nanofiber can be used to modify the surface of a substrate. When the nanofiber includes a thermally responsive polymer, the physical properties of the surface can be controlled by controlling the temperature of the system, thus controlling the ability of the surface to bind to a biologically active material of interest.Type: GrantFiled: December 10, 2012Date of Patent: August 25, 2015Assignee: INNOVATIVE SURFACE TECHNOLOGIES, INC.Inventors: Tahmina Naqvi, Jie Wen, Patrick Guire
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Patent number: 9096924Abstract: The present invention is directed to compositions, baths, and methods for composite plating including polytetrafluoroethylene (PTFE), and more particularly, to compositions, baths, and methods of composite plating with PTFE in a metal or alloy matrix where the materials used in the process contain no or essentially no PFOS (perfluorooctane sulfonate) and/or no PFOA (perfluorooctanoic acid).Type: GrantFiled: October 24, 2013Date of Patent: August 4, 2015Assignee: SURFACE TECHNOLOGY, INC.Inventors: Michael David Feldstein, Thomas S. Lancsek
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Patent number: 8936907Abstract: The invention is directed to transfection reagents for the delivery of nucleic acids into neural cells, compositions including the reagents, methods of preparation of such reagents, methods of transfecting cells with such reagents, and uses thereof. In preferred embodiments the reagents comprise horseradish peroxidase and/or a polycarboxylic acid such as poly(acrylic acid) or poly(methacrylic acid).Type: GrantFiled: February 7, 2012Date of Patent: January 20, 2015Assignee: Innovative Surface Technologies, Inc.Inventors: Eric Guire, Jie Wen
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Patent number: 8815259Abstract: The invention describes nanotextured super hydrophobic coatings that contain active agents which can elute from the coating over a period of time.Type: GrantFiled: September 15, 2009Date of Patent: August 26, 2014Assignee: Innovative Surface Technologies, Inc.Inventors: Kristin S. Taton, Patrick E. Guire, Laurie R. Lawin, Jie Wen
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Publication number: 20140205849Abstract: The invention provides compositions that include crosslinking agents having multiple photoactivatable groups, such as diaryl ketones, or a diaryl ketone, such as benzophenone, and at least one polymerizable monomer, such as a zwitterionic monomer. The compositions are useful as surface coating agents that provide brush type polymeric coatings. These polymeric coatings can be used on medical devices, such as artificial joints, to reduce wear and tear between the components of the joint and thus reduce or eliminate debris generated by friction between the joint components.Type: ApplicationFiled: March 26, 2014Publication date: July 24, 2014Applicant: Innovative Surface Technologies, Inc.Inventors: Jie Wen, Laurie R. Lawin, Patrick Guire
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Publication number: 20140199468Abstract: A nanofiber is formed by combining one or more natural or synthetic polymeric materials and one or more than one cross-linking agents having at least two latent reactive activatable groups. The latent reactive activatable nanofiber may be used to modify the surface of a substrate by activating at least one of the latent reactive activatable groups to bond the nanofiber to the surface by the formation of a covalent bond between the surface of the substrate and the latent reactive activatable group. Some of the remaining latent reactive activatable group(s) are left accessible on the surface of the substrate, and may be used for further surface modification of the substrate. Biologically active materials may be immobilized on the nanofiber modified surface by reacting with the latent reactive groups that are accessible on the surface of the substrate.Type: ApplicationFiled: March 10, 2014Publication date: July 17, 2014Applicant: Innovative Surface Technologies, Inc.Inventors: Jie Wen, Patrick E. Guire
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Patent number: 8709809Abstract: A nanofiber is formed by combining one or more natural or synthetic polymeric materials and one or more than one cross-linking agents having at least two latent reactive activatable groups. The latent reactive activatable nanofiber may be used to modify the surface of a substrate by activating at least one of the latent reactive activatable groups to bond the nanofiber to the surface by the formation of a covalent bond between the surface of the substrate and the latent reactive activatable group. Some of the remaining latent reactive activatable group(s) are left accessible on the surface of the substrate, and may be used for further surface modification of the substrate. Biologically active materials may be immobilized on the nanofiber modified surface by reacting with the latent reactive groups that are accessible on the surface of the substrate.Type: GrantFiled: June 20, 2008Date of Patent: April 29, 2014Assignee: Innovative Surface Technologies, Inc.Inventors: Jie Wen, Patrick E. Guire
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Patent number: 8691983Abstract: The invention provides compositions that include crosslinking agents having multiple photoactivatable groups, such as diaryl ketones, or a diaryl ketone, such as benzophenone, and at least one polymerizable monomer, such as a zwitterionic monomer. The compositions are useful as surface coating agents that provide brush type polymeric coatings. These polymeric coatings can be used on medical devices, such as artificial joints, to reduce wear and tear between the components of the joint and thus reduce or eliminate debris generated by friction between the joint components.Type: GrantFiled: March 1, 2010Date of Patent: April 8, 2014Assignee: Innovative Surface Technologies, Inc.Inventors: Jie Wen, Laurie R. Lawin, Patrick Guire
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Publication number: 20140011938Abstract: The invention describes novel compositions that include a cross linking compound, a polymer and a 1 nm to about a 25 micron sized particle optionally with an oxide layer. In particular, the particle is a silica and one which has been pretreated with a silane.Type: ApplicationFiled: July 29, 2013Publication date: January 9, 2014Applicant: INNOVATIVE SURFACE TECHNOLOGIES, INC.Inventors: Patrick E. Guire, Kristin Taton, Jie Wen, Laurie R. Lawin
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Patent number: 8598260Abstract: The present invention is directed to compositions, baths, and methods for composite plating including polytetrafluoroethylene (PTFE), and more particularly, to compositions, baths, and methods of composite plating with PTFE in a metal or alloy matrix where the materials used in the process contain no or essentially no PFOS (perfluorooctane sulfonate) and/or no PFOA (perfluorooctanoic acid).Type: GrantFiled: February 22, 2011Date of Patent: December 3, 2013Assignee: Surface Technology, Inc.Inventors: Michael David Feldstein, Thomas S. Lancsek
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Patent number: 8496857Abstract: The invention describes novel compositions that include a cross linking compound, a polymer and a 1 nm to about a 25 micron sized particle optionally with an oxide layer. In particular, the particle is a silica and one which has been pretreated with a silane.Type: GrantFiled: June 23, 2011Date of Patent: July 30, 2013Assignee: Innovative Surface Technologies, Inc.Inventors: Patrick E. Guire, Kristin Taton, Jie Wen, Laurie R. Lawin
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Publication number: 20130048503Abstract: A method for repairing a blade forming a cathode and having a surface to be coated defining a critical area, utilizing an anode, an electrolyte bath including insoluble particles, and a mounting on which the blade is mounted in a working position relative to a reference wall. The mounting is placed in the bath, and the particles and the metal of the anode are co-deposited to form the coating on the surface to be coated. The anode is typically placed facing the critical area and the mounting includes a mechanism for monitoring current lines to obtain a coating with a relatively constant, predetermined thickness for the critical area, that gradually falls to a value of substantially zero along edges of the coating.Type: ApplicationFiled: December 28, 2010Publication date: February 28, 2013Applicants: SNECMA, PRAXAIR SURFACE TECHNOLOGIES INC.Inventors: Justine Menuey, Frederic Braillard, John Foster, Stephen Owens, Alan Taylor, Martin Chatterney
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Patent number: 8147601Abstract: This invention is directed to a process for electrolessly metallizing an article, as well as to a plating bath and the subsequent plated substrate. The process comprises contacting the surface of an article with an electroless metallizing bath which may be essentially free of toxic and/or heavy metals.Type: GrantFiled: December 7, 2010Date of Patent: April 3, 2012Assignee: Surface Technology, Inc.Inventors: Michael Feldstein, Thomas Stephen Lancsek, Jijeesh Jose Thottathil
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Publication number: 20110223336Abstract: The invention describes novel compositions of crosslinkers that include at least two pendent photoactivatable groups, such as benzophenone moieties, and an initiator, such as acetophenone.Type: ApplicationFiled: September 3, 2009Publication date: September 15, 2011Applicant: INNOVATIVE SURFACE TECHNOLOGIES, INC.Inventors: Timothy A. Bloomquist, Mark W. Josephson, Laurie R. Lawin, Kristin S. Taton, Jie Wen