Abstract: A method, device, and system for reducing inhomogeneity in an imaging magnetic field during magnetic resonance imaging is described. The method includes generating a corrective magnetic field during imaging, the corrective magnetic field having a first magnetic field component and a second magnetic field component with a phase separation therebetween. The first and second components are generated according to a stability parameter decomposed from a stability field that correct an instability identified within the imaging magnetic field.

Abstract: An optical imaging system for imaging a target during a medical procedure, the imaging system involving an optical assembly having moveable zoom optics and moveable focus optics, a zoom actuator and a focus actuator for positioning the zoom and focus optics, respectively, a controller for controlling the zoom and focus actuators independently in response to received control input, a camera for capturing an image of the target from the optical assembly, the system capable of performing autofocus during a medical procedure.

Abstract: A system and methods for labeling tractography, having a tract segmentation and a tract labeling atlas, in a presence of a lesion in a brain, involving: a graphical user interface (GUI) comprising a tool configured to facilitate adjusting a displacement for intraoperatively reperforming the tract segmentation in approximately real time, modeling deformation of the tract labeling atlas by facilitating modeling a force exerted by the lesion on the brain, and defining parameters of a size, a shape, and a level of the displacement condition; and a processor in communication with the GUI and configured to: determine whether an infiltration condition and a displacement condition appears in the tractography; if the infiltration condition and the displacement condition is determined to appear in the tractography, estimate the infiltration condition and the displacement condition; if the displacement condition is determined to appear in the tractography, instruct the GUI to render the tool and model the force exerted

Abstract: Optionally adjustable head coil system and methods for enhancing and/or optimizing magnetic resonance imaging, involving a housing, the housing having at least one portion, the at least one portion having a lower portion, an upper portion, and opposing side portions, each at least one portion optionally in movable relation to any other portion for facilitating adjustability, each at least one portion configured to accommodate at least one radio-frequency coil, and the upper and lower portions each optionally configured to overlap and engage the opposing side portions for facilitating decoupling the at least one radio-frequency coil, and a tongue portion optionally in movable relation to any other portion for facilitating adjustability, engageable with the lower portion, and fixably couple-able with a transporter.

Abstract: Described here are systems and methods for imaging a subject with a magnetic resonance imaging (“MRI”) system using magnetic field gradients generated by one or more gradient coils operating with gradient coil settings (e.g., gradient amplitudes, gradient slew rates) above a threshold at which peripheral nerve stimulation (“PNS”) is likely to be induced in the subject. A dielectric assembly is positioned adjacent a skin surface of the subject such that the dielectric assembly attenuates the local electric fields induced by the magnetic field gradients, which would be likely to induce PNS when the dielectric assembly is not arranged adjacent the skin surface of the subject. As a result of the dielectric assembly placed adjacent the skin surface of the subject, the gradient coil settings can be increased above the threshold without inducing PNS in the subject.

Abstract: A magnetic resonance imaging (MRI) system includes a set of magnet coils for generating a magnetic field. The set of magnet coils are composed of a superconducting material. The system further includes a mechanical cryocooler in thermal contact with the set of magnet coils and operable to reduce and maintain a temperature of the set of magnet coils below a transition temperature of the superconducting material, and an energy storage device coupled to the set of magnet coils. The energy storage device may be capable of receiving and storing energy dissipated from the set of magnet coils during rapid shutdown of the set of magnet coils. The system may also include a controller coupled to the energy storage device. The controller may be programmed to recharge the set of magnet coils using the energy stored in the energy storage device during the rapid shutdown of the set of magnet coils.

Abstract: Methods and apparatuses for performing patient registration. 3D scan data from a 3D scanner, preoperative image data, first tracking data from a first tracking system, and second tracking data from a second tracking system are mapped to a common coordinate space. The 3D scan data and the first tracking data are mapped to each other using a transformation that is determined based on a calibration relating the 3D scan coordinate space and the tracking coordinate space. The 3D scan data and the preoperative image data are mapped to each other using a surface matching algorithm. The first tracking data and the second tracking data are mapped to each other based on tracking of the patient reference device.

Abstract: A method is provided for magnetic resonance (MR) imaging near metal, including acquiring an image at a first magnetic field from a subject that includes a metal object, acquiring an image at a second magnetic field, and combining the images to provide a corrected image with reduced metal distortion. An MR imaging system for measuring near metal is also provided including a superconducting magnet to provide a magnetic field, a power supply for a current to ramp the magnetic field, a cryocooler in contact with the superconducting magnet, a magnetic field controller programmed to ramp the main magnetic field by adjusting the current generated by the power supply, a radio frequency system for transmitting and receiving signals, and a data acquisition and processing system to receive the MR signals, generate image data sets and combine the image data sets to provide a corrected image having a reduced metal distortion.

Abstract: The present invention provides a system and method for collection, storage and processing of tissues and cells. The system includes a collection container with chambers for storing and processing tissues, which are controllably separated and maintain a physiologic environment for the tissues. The system also includes a fluidic device for isolating target cells of interest. The method includes receiving the tissue into a collection chamber, transferring the tissue to a processing chamber, dissociating the tissue into single cells, and passing the single cells to a device for isolating one or more target cells.

Abstract: A flexible high-resolution endoscope apparatus and methods involving a plurality of optical fiber bundles; a plurality of lenses in a one-to-one correspondence with the plurality of optical fiber bundles, each lens of the plurality of lenses comprising a distinct depth of field and a distinct angle of view in relation to another lens of the plurality of lenses; and a plurality of cameras in a one-to-one correspondence with the plurality of optical fiber bundles.

Abstract: Methods for correcting a non-uniform power response of a radiofrequency (“RF”) transmit coil used in magnetic resonance imaging (“MRI”) are described. Transmit power response data for an RF transmit coil are processed to compute RF amplitude scaling factors for the RF transmit coil as a function of transmit frequency offset. The RF amplitude scaling factors can be used to correct transmitted RF power, and thus flip angle, to be more uniform over a range of transmit frequency offsets, as may be encountered when imaging with lower field MRI systems or MRI systems with high strength or asymmetric gradients.

Abstract: Systems and methods involving: a housing having a bore in which a subject to be imaged is placed; a main magnet configured to generate a volume of magnetic field within the bore, the volume of magnetic field having inhomogeneity below a defined threshold; gradient coils configured to linearly vary the volume of magnetic field as a function of spatial location; pulse-generating coils configured to generate and apply radio frequency (RF) pulses to the volume of magnetic field in sequence to scan the portion of the subject; shim gradient coils configured to perturb a spatial distribution of the linearly varying volume of magnetic field; and a control unit configured to operate the gradient coils, pulse-generating coils, and shim gradient coils such that only the user-defined region within the volume of magnetic field is imaged.

Abstract: The present disclosure reports on a method to first determine the required electromagnetic stream function, and then iterate on the contouring of the stream function to optimize the force, torque, shielding, and/or mutual inductance of the design after-the-fact without compromising the electromagnetic performance and an electromagnetic coil manufacture according to the method. These parameters are sensitive to the precise positioning of the discrete wires.

Abstract: An optical imaging system for imaging a target during a medical procedure, the imaging system involving an optical assembly having moveable zoom optics and moveable focus optics, a zoom actuator and a focus actuator for positioning the zoom and focus optics, respectively, a controller for controlling the zoom and focus actuators independently in response to received control input, a camera for capturing an image of the target from the optical assembly, the system capable of performing autofocus during a medical procedure.

Abstract: Some implementations provide a system that includes: a housing having a bore in which a subject to be image is placed; a main magnet configured to generate a volume of magnetic field within the bore, the volume of magnetic field having inhomogeneity below a defined threshold; one or more gradient coils configured to linearly vary the volume of magnetic field as a function of spatial location; one or more pulse generating coils configured to generate and apply radio frequency (RF) pulses to the volume of magnetic field in sequence to scan the portion of the subject; one or more shim gradient coils configured to perturb a spatial distribution of the linearly varying volume of magnetic field; and a control unit configured to operate the gradient coils, pulse generating coils, and shim gradient coils such that only the user-defined region within the volume of magnetic field is imaged.

Abstract: Methods and systems for providing feedback during a medical procedure are provided. A saved optical image of a field of view (FOV) of a site of the medical procedure is obtained along with a live optical image of the FOV of the site during the medical procedure. Navigational information relative to the site of the medical procedure is determined. The navigational information is then mapped to a common coordinate space, to determine the navigational information relative to the FOV of the saved and live optical images of the surgical site. Virtual representations of the navigational information is overlaid on the saved and/or live optical images and displayed on at least one display.

Abstract: A system and method of tractography labelling in the presence of a brain lesion. According to the disclosure, a composition of free water correction (FWC) tractography and non-FWC tractography sets into a single tractography set with a ‘degree of free water’ value assigned to each tract and/or fragment of tract geometry. A slider graphical user interface is introduced to dynamically adjust the free water threshold value that controls what tracts and/or fragments of tract geometry get shown. For example, only tracts or fragments of tract geometry with a degree of free water below the threshold are shown while the rest are hidden.

Abstract: The navigation systems and methods facilitate aligning a tool in relation to a trajectory in real-time to receive input data from a pre-operative plan image, at least one multi-modal image, and at least one real-time multi-modal image; interactively track at least one neural fiber, whereby interactively tracked fiber data is obtainable; automatically generate output data by way of data transformation using the input data and the interactively tracked neural fiber data; and transmit the output data to at least one of: at least one display device for rendering at least one real-time interactive navigation display for facilitating neural navigation, and at least one drive device for positioning at least one tracking device in relation to the tool in real-time, whereby real-time alignment data is achievable, and whereby at least one neurological structure is preservable.

Abstract: Systems and methods involving a control and processing system interfaceable with a device, a tracking system, and a data storage device, the control and processing system having a processor configured by a set of instructions storable in relation to a nontransient memory device to: identify the at least one device, via the tracking system operating with at least one of an electromagnetic system and a radiofrequency (RF) system, during a medical procedure; obtain an image of a region of interest associated with the medical procedure; process the image to identify a context measure associated with a current state of the medical procedure; obtain a parameter for adaptively configuring the device during the medical procedure, the parameter customizable based on the context measure, the parameter providable for the device according to a prioritized list, and the device reverting to a default configuration when another device is removed from the region of interest; and configure the device according to the paramete