Abstract: A method and instrument for preparing a surface of a joint is provided. The glenoid surface is adapted for receiving a prosthetic component having a feature closely conforming to the surface. The prosthetic component provides a bearing surface for a head portion of a long bone. The instrument includes a guide having a first feature and a second feature and a tool. The tool is used for cooperation with the first feature for preparing the surface. The first feature is adapted to at least partially control the position of the tool as it prepares the surface. The second feature is adapted to assist in positioning of the guide with respect to the joint.

Abstract: A bone cement formulation having i) a PMMA powder fraction designed for quick reaction and ii) a polymerization inhibitor provided in a delayed release form. This allows the cement to obtain an initial viscosity suitable for injection and a long working time.

Abstract: An occlusion device suitable for endovascular treatment of an aneurysm in a blood vessel in a patient, including a substantially tubular structure having a proximal end region and a distal end region, having a first, expanded condition and a second, collapsed condition. The device has dimensions in the second, collapsed condition suitable for insertion through vasculature of the patient and through a neck of the aneurysm. The device further includes a control ring having a substantially annular body disposed on the proximal end region of the structure and at least substantially circumscribing the proximal end region to prevent radial expansion of the proximal end region and to provide an engagement feature during manipulation of the occlusion device.

Abstract: A system and method for draining at least one type of bodily fluid from a patient, including a chamber capable of being adjusted to hold one of at least a first volume of fluid and a second, smaller volume of fluid. The chamber has an inlet end with a barrier defining an opening and has an outlet end defining an outlet passage. The system further includes a valve with a valve seat and a valve closure member to define a usable volume within the chamber, and a movable adjustment member with a shaft passable through the opening in the barrier and terminating within the chamber at a first end. The first end of the shaft is connected to the valve seat, and the shaft has a plurality of features along its length engagable with corresponding engagement features in a fixed relationship with the barrier to enable the shaft to be advanced into the chamber to reduce the usable volume to be less than the first volume.

Abstract: An housing for a medical device includes an insert configured for removable insertion into the housing, outer dimensions of the insert conforming to inner dimensions of the housing to prevent movement thereof within the housing. The insert includes first and second planar walls connected to one another and having first and second openings extending therethrough. The first and second walls are movable between an open configuration in which the first and second walls are separated from one another and a closed configuration in which the first and second walls are folded to contact one another such that the first and second openings are aligned to define a medical device receiving cavity configured to house a medical device. In the closed configuration, the first and second walls apply a frictional clamping force to a packet containing the medical device to prevent movement of the medical device relative to the inlay.

Abstract: A number of orthopaedic surgical instruments are disclosed. A method, apparatus, and system for fabricating such instruments are also disclosed.

Abstract: Customized patient-specific orthopaedic surgical instruments are disclosed. Methods for fabricating and using such instruments are also disclosed.

Abstract: A fixation assembly having a driver, a holding sleeve, and an alignment mechanism is disclosed. The driver may include a driver body and a coupling extending from a distal end of the driver body. The holding sleeve may have a holding sleeve body, a channel extending through the holding sleeve body, and a fixation element coupler disposed at a distal portion of the holding sleeve body. The channel may be configured to receive the driver, and the fixation element coupler may be configured to temporarily hold a fixation element. The alignment mechanism may extend from the holding sleeve, and may have at least one alignment member configured to engage an underlying structure to which the fixation element is to be affixed so as to align the fixation element and driver assembly with respect to the underlying structure.

Abstract: A bone plate having a first, bone-facing surface and an opposing second surface has an elongate shaft portion and a head portion that is shorter and wider in comparison thereto, with at least one through hole extending through the bone plate from the first surface to the second surface in the shaft portion. The through hole comprises a variable-angle portion with a hole axis configured to receive a threaded head of a locking screw therein at a desired angle within a permitted range of angulation relative to the hole axis. The second surface has at least one depression which extends therein along a portion of the second surface between the side wall and the through hole, the depression extending about a periphery of the through hole.

Abstract: Systems of manipulating (e.g., compressing or distracting) a spinal construct are provided herein. In general, the system can include a surgical sleeve extending from a vertebra and a fulcrum movably coupled to some component of the system thereby allowing the fulcrum to be positioned at various location along the length of the sleeve. As indicated, the fulcrum can be movably coupled to virtually any component of the system. For example, the fulcrum can be movably coupled to the surgical sleeve, to a manipulation device sized and configured to receive the surgical sleeve, to a driver configured to apply a manipulation force, etc. Additionally, methods for manipulating a spinal construct are also provided herein.

Abstract: A joint prosthesis includes a bone engaging portion, such as a stem, and articulating component, such as a humeral head, and an insert component that supports the articulating component and is removable from the stem. A mating component mates with the humeral head and is configured to engage the insert component at adjustable angles according to the anatomy of the patient's joint. In a revision surgery, the stem remains within the patient's bone while the insert component is removed with the mating component and humeral head fixed to the insert component. A new insert component may be prepared with the mating component and humeral head oriented to replicate the angular orientation of the previous prosthesis. The new insert component is then mounted within an insert cavity in the implanted stem and rigidly fastened to complete the revision.

Abstract: An orthopaedic prosthesis for use in a hip replacement surgery. The orthopaedic prosthesis includes a metallic foam shell and a metallic core. The metallic core includes a neck configured to receive a femoral head component and a stem extending through the metallic foam shell.

Abstract: A surgical instrument including a customized patient-specific guide block is disclosed. The customized patient-specific guide block includes a first surface, a bone-facing surface, a second surface positioned opposite the first surface and the bone-facing surface, and a guide pin hole extending between the second surface and the bone-facing surface. The first surface has a customized prosthesis-specific negative contour shaped to match a corresponding contour of a prosthetic component, and the customized prosthesis-specific negative contour includes a concave surface shaped to match a convex surface of the corresponding contour of the prosthetic component. A method of performing an orthopaedic surgical procedure is also disclosed.

Abstract: A vertebral manipulation assembly includes a vertebral fixation assembly that is configured to be attached to a first vertebra and a second vertebra that is spaced from the first vertebra. The vertebral fixation assembly can include vertebral fixation members that attach to the first and second vertebrae, respectively. The vertebral manipulation assembly can further include a vertebral manipulation instrument that is configured to be coupled to the vertebral fixation assembly, and provide a first compression force that biases the first and second vertebral fixation members to move toward each other, and a second distraction force that biases the first and second vertebral fixation members to move away from each other. The vertebral manipulation instrument can include a coarse adjustment assembly that, when actuated, causes the first and second vertebral fixation members to incrementally move with respect to each other in first increments.

Abstract: A method of revising a patient having a fusion cage implanted within a spinal column, involving percutaneously delivering a first end of a tube to the spinal column, fluidly connecting the first end of the tube to the fusion cage, and delivering a bone growth agent into the fusion cage through the tube.

Abstract: The osteosynthetic device for the fixation of a bone or bone fragments has a longitudinal axis (6) and comprises a bone screw (1) with a shaft (2) bearing a thread (3), a front end (4) and a rear end (5), said thread (3) having a maximum outer diameter d; and a wing-like blade (7) with a leading end (8) being connected to the front end (4) of the bone screw (1) and a trailing end (9) being connected to the rear end (5) of the bone screw (1). The blade (7) is further provided with a coaxial longitudinal aperture (17) having a length I extending between the leading end (8) and the trailing end (9) and a width w?d. Further the blade (7) is coaxially and rotatably mounted on said shaft (3) of said bone screw (1).

Abstract: A method and apparatus for replacing damaged meniscal tissue includes a meniscus implant including a porous body having a plurality of interconnected open micro-pores and one or more open cavities for receiving meniscal tissue. The interconnected micro-pores are arranged to allow fluid to flow into the porous body and are in fluid communication with the one or more open cavities.

Abstract: The present disclosure relates to methods and devices for surgically manipulating tissue. In general, the methods and devices can include an elongate retractor shaft having a distal retractor tip that is configured to manipulate tissue, for example the tip can be configured to separate muscle and nerve fibers surrounding a vertebra. The elongate retractor shaft can include an illumination source such that at least a portion of the surgical field is illuminated by the device when the device is used in the body. A sensor can also or alternatively be included on the elongate retractor shaft, for example on the blunt retraction tip, such that the sensor can monitor physiological parameters of the tissue in or adjacent to the surgical field.

Abstract: Compositions and methods of using cells derived from umbilical cord tissue, to stimulate and support angiogenesis, to improve blood flow, to regenerate, repair, and improve skeletal muscle damaged by a peripheral ischemic event, and to protect skeletal muscle from ischemic damage in peripheral vascular disease patients are disclosed. In particular, methods of treating a patient having a peripheral vascular disease with umbilical derived cells and fibrin glue are disclosed.

Abstract: Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s).