Abstract: A graft anchor has first and second arms each having a leading end, a trailing end, an inner surface, and an outer bone contactable surface. The graft anchor also has a resilient bridge extending between the inner surface of the first arm and the inner surface of the second arm to space apart the first arm and the second arm. The resilient bridge defines a graft receiving pathway between the inner surfaces of the first and second arms. The resilient bridge also defines a deflection point about which a force acting upon the resilient bridge in a direction from the leading end to the trailing end causes the leading ends of the first and second arms to move toward one another and the trailing ends of the first and second arms to move away from one another.

Abstract: A bone plate is configured for pancarpal arthrodesis. The bone plate can include a plurality of apertures that can be aligned with the metacarpal bones. The apertures can include a first portion and second portion that is longitudinally and laterally offset with respect to the first portion.

Abstract: An orthopedic implant comprising a metallic substrate coated with a diamond-like carbon (DLC) layer, and a layer of a polymeric material placed over the DLC layer that is less stiff than the substrate, and methods of manufacturing the same.

Abstract: An intervertebral prosthesis or disk prosthesis comprising a front side, a rear side, an upper side which can be placed on the base plate of vertebral body, a lower side which can be placed on the base plate of a vertebral body, a right side, a left side, a cavity which can receive a fluid hydraulic osteocementum, an opening in the cavity and several outlets out from the cavity. The total of the transversal surfaces of the outlets SV on the front side, the total of the transversal surfaces of the outlets SH on the rear side, the total of the transversal surfaces of the outlets SR on the right side and the total of the transversal surfaces of the outlets on the left side satisfy the following conditions: SL>SR or SR>SL or SH>SV or SV>SH.

Abstract: A bone fixation system has a bone implant with an implant body. The implant body defines an upper surface, a bone-facing surface spaced from the upper surface along a transverse direction, and at least one aperture defined by an inner wall. A bone fixation element is configured for insertion at least partially through the aperture. The bone fixation element has a head and a shaft that extends relative to the head in a distal direction. The head defines a ridge and at least one thread that is spaced from the ridge in the distal direction. The ridge is configured to compress a bone implant against the at least one thread so as to fixedly retain the bone implant with respect to the head.

Abstract: An assembly tool for assembly of a first component of a prosthesis to a second component of the prosthesis for use in joint arthroplasty. The tool includes a first member operably associated with the first component and a second member operably associated with the second component. The second member includes a cap having a threaded recess and further includes a threaded rod adapted to engage the threaded recess so as to move the second member relative to the first member and the threaded rod is made of a harder metal than the threaded recess.

Abstract: An intervertebral implant comprises a number of components including upper and lower endplates and one or more inserts configured to be disposed between the upper and lower endplates. Complimentary curved articulation surfaces are defined on the insert-facing surfaces of the upper and lower endplates and on the corresponding upper and lower surfaces of each of the inserts. The components of the implant articulate with respect to each other along shared articulation surfaces. At least two pairs of shared articulation surfaces are defined, each pair having a different length radius. The components of the implant can be configured with retainers, such that the implant is retained in an assembled configuration when disposed within an intervertebral space.

Abstract: Spinal rod approximator for seating a stabilizing rod in a rod-receiving portion of a spinal implant and inserting closure mechanism is provided. In one embodiment, a spinal rod approximator is provided including a body with gripping branches, inserter shaft, threaded collar, and outer sleeve.

Abstract: A vertebral adjustment system configured to move individual vertebral bodies relative to the other vertebral bodies to thereby realign the spine. The system may include a frame, and a plurality of alignment devices coupled to the frame and to the individual vertebral bodies. By manipulated the alignment devices the vertebral bodies to which they are attached may be moved.

Abstract: A system is provided for inserting and securing, through a suprapatellar region of a leg, a nail into a medullary canal of a bone. The system can include a flexible sleeve configured to be partially inserted in the leg. The flexible sleeve can define a leading end and a trailing end spaced apart from the leading end along a first axis. The flexible sleeve can define a first cannulation that extends along the first axis between the leading and trailing ends. The first cannulation can be sized to receive therethrough at least the intramedullary nail. The system can further include a retaining member configured support at least a portion of the flexible sleeve. The retaining member can be configured to position the flexible sleeve through the suprapatellar region of the leg such that the flexible sleeve leading end is aligned with the proximal end of the bone. The intramedullary nail can be insertable through the flexible sleeve and into the medullary canal.

Abstract: A catheter device that includes a double-threaded guidance wire that allows multiple use of a compliant cavity creation device (i.e., treatment of more than one level). The double-threaded guidance wire may be connected with the luer part of the device and a distal part of the balloon using a threaded engagement to avoid lengthening of the inner tube, avoid lengthening of the balloon, and to limit the plastic deformation of the system in axial direction. In other implementations, the double-threaded guidance wire may be reconnected to the distal part of the balloon with a distal thread of the double-threaded guidance wire in order to restore the nominal length.

Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature.

Abstract: A post that is configured to be coupled to a head of a bone fixation element that is attached to a bone part can include a post body that is elongate along a first direction and defines a proximal end and a distal end that is spaced from the proximal end along the first direction. The post body can include an internal surface that defines a socket at the distal end. The socket can be configured to receive the head of the bone fixation element. The post can further include a locking member that is disposed within the socket such that when the socket receives the head of the bone fixation element the locking member couples the post body to the bone fixation element. The post body is polyaxially pivotable relative to the head when the post body is coupled to the bone fixation element.

Abstract: A device for osteosynthesis includes a body having a proximal surface, a distal surface configured and dimensioned to face a target portion of bone over which the body is to be mounted and a through opening extending through the body from the proximal surface to the distal surface along a central axis. The through hole includes a first protrusion extending from an inner surface thereof toward the central axis. The first protrusion is biased toward an unstressed state in which the first protrusion extends into the through opening to a first distance from the central axis. The first protrusion is movable toward the inner surface when subjected to a force directed outward from the central axis.

Abstract: Various spinal implants and methods for stabilizing the spine are provided. In one exemplary embodiment, a spinal implant is provided having an expandable container with an interior volume that is selectively expandable between a compressed condition and an expanded condition. The expandable container is coupled to a superior endplate member having a bone-contacting surface and an engagement surface effective to mate with a superior surface of the expandable container, and an inferior endplate member having a bone-contacting surface and an engagement surface effective to mate with an inferior surface of the expandable container. In addition, at least one inlet port is formed in the expandable container and is effective to communicate a fluid to at least one cavity disposed within the interior volume of the expandable container.

Abstract: Compositions and methods for the growth and expansion of mammalian cells in culture are provided. In particular, methods for the growth and expansion of postpartum-derived cells in vitro are provided using surfaces such as microcarrier beads.

Abstract: An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon. In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.

Abstract: Customized patient-specific orthopaedic surgical instruments are disclosed. Methods for fabricating and using such instruments are also disclosed.

Abstract: A disassembly tool for disassembly of a first component of a prosthesis to a second component of the prosthesis for use in joint arthroplasty. The tool includes a first member having a radial portion operably associated with the first component and adapted to exert a radial force on the first component. A second member operably associated with the second component is also included and the second member has a second member longitudinal axis. A drive mechanism is coupled to the second member, such that as the drive mechanism is activated, the second member exerts a force against the second component in the direction of the longitudinal axis. Such exertion of force against the second member further causes the second member to move relative to the first member along the second member longitudinal axis.

Abstract: An installation tool that is useful for the efficient and effective placement of an article, such as an artificial disc, between adjacent vertebral bodies is provided. The installation tool can be provided as a kit having modular components which allow the surgeon to select from among a variety of components to assemble an installation tool that is optimized for its intended use. The installation tool of the invention generally includes a pair of opposed levers, each of which has a proximal handle portion and a distal portion. A fulcrum is disposed between the two levers to enable proper operation of the tool. The tool further includes a pusher block that is positioned between the two levers and is selectively movable between an initial location distal of the fulcrum and a final location adjacent the distal end of the levers. The pusher block includes a proximal end, a distal end, and a bore extending at least partially therethrough.