Abstract: An acetabular hip implant includes an acetabular shell component, a first insert secured to the acetabular shell component, a second insert secured to the first insert, and a femoral head configured to be secured to the second insert. The first insert is permitted to rotate relative to the acetabular shell about a first axis, the second insert is permitted to rotate relative to the first insert about a second axis, and the femoral head is permitted to rotate relative to the second insert about a third axis.

Abstract: A method for manipulating a vertebra includes connecting a first bone anchor to a first vertebra, connecting a second bone anchor to a second bone anchor, positioning a spinal rod in a receiving member of the first bone anchor and in a receiving member of the second bone anchor, connecting a first instrument to the receiving member of the first bone anchor, and manipulating the first instrument to rotate first bone anchor and the first vertebra relative to the second vertebra.

Abstract: A biocompatible, resorbable composite for osteosynthesis includes osteoconductive particles dispersed within a porous polymer matrix having a plurality of fluid passageways that expose at least a portion of a plurality of the osteoconductive particles to an exterior of the polymer matrix. The composite may further include a chemical additive incorporated within the polymer matrix, the chemical additive being configured to modify one or more of acidity, degradation rate, melting point, hydrophilicity, and hydrophobicity of the polymer matrix. A method for making the composite includes mixing the osteoconductive particles with polymer material and the chemical additive to form a mixture and treating the mixture to bind the osteoconductive particles with the polymer material to create a solid unit.

Abstract: Methods and devices are provided for passively locking a bone screw within a bone plate. In particular, the methods and devices allow a bone screw to be locked within a thru-hole in a bone plate without requiring any additional locking steps. In an exemplary embodiment, an annular feature is provided in a thru-hole of a bone plate, or in a bushing that is disposed within a thru-hole of a bone plate, for engaging a bone screw. The annular feature can be configured such that it allows the bone screw to be inserted through the thru-hole at various insertion angles while still being effective to prevent back-out of the bone screw, thereby locking the screw to the plate.

Abstract: In a device for injecting bone cement, the discharge direction of the bone cement after insertion of the cannula should be controllable in a certain region. This is made possible through a radial exit aperture (5) which is provided on the front end of the cannula (3). Since the cannula is inserted with the aid of a guide wire (1), it has an orifice (4) on its front end, which orifice must be closed off by means of a ball (15) prior to the injection. A plunger serves to insert the ball (15). So that the situation of the radial aperture (5) is known at all times, even with inserted cannula, the handle (17) of the cannula has an asymmetrical shape.

Abstract: A surgical nail for treating a fractured bone includes a nail body extending along a longitudinal axis from a trailing end to a leading end and including a trailing end locking aperture extending transversely through a trailing end portion thereof and a leading end locking aperture extending transversely through a leading end portion thereof; a trailing end connecting element located at the trailing end of the nail body adapted and configured to be coupled to a trailing end aiming guide; and a leading end connecting element at the leading end of the nail body adapted and configured to be coupled to a leading end aiming guide.

Abstract: A mobile tibial assembly includes a tibial tray and a tibial insert. The tibial tray includes a closed track. The tibial insert includes a stem configured to be inserted into the closed track and retained therein. The tibial insert is movable along the closed track once inserted.

Abstract: An intervertebral implant having a three-dimensional body and a securing plate. The intervertebral implant also includes a front plate (8) displaceably disposed as an insert with a front side of the three-dimensional body.

Abstract: A system for inserting an intramedullary nail into a bone includes (a) a handle extending from a proximal end to a distal end configured to couple to an intramedullary nail only in a desired orientation and (b) an aiming device extending from a proximal end to a distal end configured for attachment to the proximal end of the handle. The aiming device includes a guide opening extending therethrough sized and shaped to accommodate a protective sleeve therein. The guide opening is located and oriented so that, when the aiming device and the handle are coupled to one another, a bone fixation receiving hole in an intramedullary nail coupled to the handle is aligned with the guide opening. The aiming device further includes a locking pin fixedly mounted thereto. The locking pin extends into the guide opening to engage a protective sleeve inserted therein.

Abstract: A tibial insert includes a platform defining an upper bearing surface and a bottom surface. A keel of the tibial insert is coupled to the bottom surface of the platform and includes a bore extending along a width of the keel. The bore is formed to receive a fastener therein.

Abstract: The present invention generally provides a polyaxial fixation device having a shank with a spherical head formed on a proximal end thereof, and a receiver member having an axial passage formed therein that is adapted to polyaxially seat the spherical head of the shank. The polyaxial bone screw further includes an engagement member that is adapted to provide sufficient friction between the spherical head and the receiver member to enable the shank to be maintained in a desired angular orientation before locking the spherical head within the receiver member.

Abstract: A bone plate comprises a first surface and a second surface in combination with a first hole extending through the bone plate from the first surface to the second surface, the hole including a compression portion and a variable angle portion open to one another by a connecting space. The compression portion includes a sloping surface adapted to engage a head of a bone fixation element inserted thereinto so that the bone fixation element imparts a force to the bone plate to move the bone plate laterally relative to a portion of bone into which the bone fixation element is inserted. The variable angle portion includes a plurality of columns positioned about a circumference of a wall of the variable angle portion. The columns are separated from one another by a plurality of positioned between adjacent pairs of columns and including a plurality of protrusions extending radially inward therefrom.

Abstract: A clamp assembly for bone fixation elements including first and second clamp structures configured to engage first and second bone fixation elements, respectively. The first clamp structure may have a first spherically contoured bearing surface. The second clamp structure may have a second spherically contoured bearing surface seated in sliding contact with the first bearing surface. A spring-loaded mechanism may apply a spring force urging the bearing surfaces together to resist pivotal movement of the clamp structures relative to each other. The clamp assembly may be used with an assembly of fixation elements to create an external fixation frame.

Abstract: A device for clamping fixation elements, which have been inserted into bone, for manipulating fragments of a fractured bone. The device incorporating a hollow body with a cavity having a wall, a clamping body moveable within the cavity between a first position and a second position, and a clamping device operably connected to the clamping body for moving the clamping body between the first position and the second position. The device being sized and configured so that when the clamping body is in the first position a free end of the fixation element(s) may be positioned between the clamping body and the wall of the cavity. Once the fixation element(s) is properly positioned within the cavity, the clamping device may be used to move the clamping body into the cavity, thereby wedging the fixation element(s) between the clamping body and the wall of the cavity. A bone fragment may then be manipulated using the device.

Abstract: This invention provides for methods of growing anchorage-dependent cells (e.g. hUTC) in culture medium comprising amino acids, vitamins, salts nucleosides, insulin, transferrin, ethanolamine and sodium selenium, wherein the culture medium is supplemented with serum. The method further comprises addition of a serum-free nutrient solution comprising amino acids, vitamins, salts nucleosides, insulin, transferrin, ethanolamine and sodium selenium. The invention also provides for culture media and serum-free nutrient solutions for growing anchorage-dependent cells.

Abstract: The present invention is directed to a surgical cutting device configured to drive a removable surgical saw blade in oscillating rotation. The saw blade is held within the cutting device at a holding member and a clamping member and removeabley attached to a drive plate.

Abstract: An intervertebral implant having an upper and a lower closing plate designed to engage the vertebral end plates. The implant has a deformable body between the closing plates. Between the deformable body and closing plates are cover plates. A plurality of fiber windings run between the cover plates to hold together the cover plates and the deformable body.

Abstract: A guide body is designed to receive longitudinal fixation elements such as wires nails, pegs or screws which are to be anchored within bone. The guide body includes a top surface, a bottom surface, and a number of openings connecting the top surface with the bottom surface. The central axes of at least two of the openings are transverse to each other. The guide body permits the insertion of fixation elements at various angles with respect to each other. The guide body may prevent fixation elements which extend into the intramedullary region or the spongiosa from being displaced either in the proximal or in the distal direction.

Abstract: A tool is disclosed for use in distracting and compressing fractures of any of a variety of bones. In particular, the tool has a pair of engaging arms, one arm having a hook element to engage a bone plate connected to one side of a fracture, and the other arm having at least one recess for engaging a head of a bone screw or guide wire connected to the other side of the fracture. Actuation of the tool causes the opposing bone segments of the fracture to be pushed apart or drawn together, depending on whether the tool handles are squeezed together or pulled apart. The tool may have a scissors joint that allows the ends of the tool to maintain a parallel alignment during operation, thus reducing the chances for misalignment of the bone segments during operation.

Abstract: Multiple, small, staple-like supports are inserted through a small tube into the disc space then rotated into position on the edge of the vertebral bodies. The tooth-like geometry of the proximal and distal faces of these staples mates with the outer edge of the vertebral body, extending past the front of the endplate anteriorly. The staples have teeth that dig into the endplate on the inside of the rim as well.