Abstract: The subject matter of the invention is the use of a ruthenium complex of the formula 1, wherein the individual substituents have meanings as indicated in the olefin metathesis reactions description, including a reaction selected from such as ring-closing metathesis (RCM), homometathesis (self-CM) or cross metathesis (CM).

Abstract: The invention provides a new process for producing ruthenium complexes represented by the Formula 1. Invention provides also the use of ruthenium complexes represented by the Formula 1 as precatalysts and/or catalysts in olefin metathesis reactions.

Abstract: A yarn reinforced bacterial cellulose hybrid composition includes a two-dimensional yarn mesh stretched and embedded within a BC sheet. Such materials are fabricated by providing a bacterial cellulose-producing bacterium; providing a suitable bacteria nutritional medium; culturing the bacterium in the nutritional medium under conditions to produce bacterial cellulose; and providing a two-dimensional yarn mesh having a defined pattern such that the yarn mesh is embedded within the bacterial cellulose.

Abstract: The present invention relates to a novel selenophenochromene hydroxamic acids as angiogenesis inhibitors, as well as methods of their manufacturing and use in different pharmaceutical compositions for the treatment or prevention of various diseases and disorders by administration of such substances.

Abstract: The invention provides a new process for producing ruthenium complexes represented by the Formula 1. Invention provides also the use of ruthenium complexes represented by the Formula 1 as precatalysts and/or catalysts in olefin metathesis reactions.

Abstract: Novel ruthenium complexes of general formula 4 in which the substituents are defined herein. The present disclosure relates also to methods for preparing such compounds and use thereof as catalysts and/or (pre)catalysts in olefin cross metathesis.

Abstract: A fluid diverting module includes a multi-position fluid diverting device comprising three-dimensional movable flow-paths with minimal tortuosity in the movable portion (the rotor) of the fluid diverting device. In some embodiments, the device is also equipped with a filtration module that is capable of filtering solid particulates from fluidic samples. The invention relates to an area of non-disruptive sampling from various sample sources including ones containing solids. The fluid diverting device maintains fluid communication between the sample source and a pressure creating device in all positions of the fluid diverting device, thus conserving the pressure inside the sample source during sampling. The sampling operation is controlled from a controller, which is equipped with a software for manual or intelligent control.

Abstract: The invention provides a new process for producing ruthenium complexes represented by the Formula 1. Invention provides also the use of ruthenium complexes represented by the Formula 1 as precatalysts and/or catalysts in olefin metathesis reactions.

Abstract: An apparatus for fixating bone includes an orthopedic implant. The orthopedic implant may be manufactured from a shape memory material such that the orthopedic implant is moveable between a natural shape and an insertion shape. The orthopedic implant defines at least a first cannulation therethrough adapted to deliver a bone augmentation material to the bone. The orthopedic implant implants into the bone in its insertion shape. After implantation of the orthopedic implant, the first cannulation facilitates delivery into the bone of a bone augmentation material that augments the bone. The orthopedic implant once implanted attempts to transition from its insertion shape to its natural shape such that the orthopedic implant fixates the bone.

Abstract: A posterior vertebral plating system comprising a plate and a plurality of attachment members. The plate has a plurality of holes extending through the plate from an upper surface to a lower surface, and the plate is configured to extend along the posterior side of at least two vertebrae adjacent at least one boney structure of each of the vertebrae. The holes are spaced in such a way that a first plurality of holes is positionable over a boney structure of a first vertebra to define a plurality of fixation points to the first vertebra and a second plurality of holes is positionable over boney structure of a second vertebra to define a plurality of fixation points to the second vertebra. The attachment members are insertable through the holes of the plate and into the boney structure of a corresponding vertebra to fix the plate to the vertebra.

Abstract: The present invention provides carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections, including drug resistant or multiple-drug resistant bacterial infections, and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

Abstract: Hydrogel compositions are provided (a) that have a continuous hydrophobic phase and a discontinuous hydrophilic phase, (b) that have a discontinuous hydrophilic phase and a continuous hydrophilic phase, or (c) that are entirely composed of a continuous hydrophilic phase. The hydrophobic phase, if present, is composed of a hydrophobic polymer, particularly a hydrophobic pressure-sensitive adhesive (PSA), a plasticizing elastomer, a tackifying resin, and an optional antioxidant. The discontinuous hydrophilic phase, if present, is composed of a crosslinked hydrophilic polymer, particularly a crosslinked cellulosic polymer such as crosslinked sodium carboxymethylcellulose. For those hydrogel compositions containing a continuous hydrophilic phase, the components of the phase include a cellulose ester composition or an acrylate polymer or copolymer, and a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding thereto.

Abstract: A composition is provided, wherein the composition comprises a water-swellable, water-insoluble polymer, a blend of a hydrophilic polymer with a complementary oligomer capable of hydrogen or electrostatic bonding to the hydrophilic polymer. The composition also includes a backing member. Active ingredients, such as a whitening agent, may be included. The composition finds utility as an oral dressing, for example, a tooth whitening composition that is applied to the teeth in need of whitening. The composition can be designed to be removed when the degree of whitening has been achieved or left in place and allowed to erode entirely. In certain embodiments, the composition is translucent. Methods for preparing and using the compositions are also disclosed.

Abstract: The group of inventions relates to a process of co-converting hydrocarbon feedstock with a high content of unsaturated hydrocarbons and aliphatic alcohols into components of high octane gasolines or aromatic hydrocarbons, as well as to catalysts of such a co-conversion. The method of co-converting hydrocarbon fractions and oxygenates into high octane components of fuels or aromatic hydrocarbons including contacting a hydrocarbon stream mixed with oxygenates with a catalyst under a reduced pressure and with heating. The process is carried under using a catalyst that contains the HZSM-5 zeolite that passed thermal and steam treatment.

Abstract: The present invention relates to a novel cancer metastasis preventing and curing selenopheno[h]chromene derivatives, as well as methods of their manufacturing and use in different pharmaceutical compositions for the treatment and/or prevention of primary cancer and its metastasis by administration of such substances.

Abstract: This invention concerns a method of synthesizing Azelaic Acid. Particular reference is made to providing a new synthetic process for preparing azelaic acid in large scale with high purity (e.g., >99.7% with any individual impurity not more than 0.1%), which can be used as an active pharmaceutical ingredient.

Abstract: A composition is provided, wherein the composition comprises a water-swellable, water insoluble polymer, a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding to the hydrophilic polymer, and a whitening agent, preferably a peroxide. The composition finds utility as a tooth whitening composition and is applied to the teeth in need of whitening, and then removed when the degree of whitening has been achieved. In certain embodiments, the composition is translucent. Methods for preparing and using the compositions are also disclosed.

Abstract: Use of 2-(5S-Methyl-2-oxo-4R-phenyl-pyrrolidin-1-yl)-acetamide or its pharmaceutically acceptable salt in manufacture of a medicament for prophylaxis and treatment of seizure.

Abstract: The invention relates to a composition, method and apparatus for determining the sequence of a nucleic acid strand utilizing a pH-sensing agent.

Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.