Abstract: A laser fusion welding device includes a 1.9 ?m laser light source, a control unit and a light spot adjusting device. The control unit is configured to control the laser light source and the light spot adjusting device to adjust a laser power density at an object to be subjected to fusion welding. The 1.9 ?m laser light source has output power of 100-500 W. The control unit includes a time control unit, a power control unit and a light spot control unit. The time control unit is configured to control a turn-on time of the laser light source. The power control unit is configured to control the output power of the laser light source. The light spot control unit is configured to control the light spot adjusting device to adjust a size of a light spot at the object to be subjected to fusion welding.

Abstract: Disclosed in the present invention is a nonlinear optical crystal. The chemical formula of the nonlinear optical crystal is MHgGeSe4, M being selected from Ba or Sr. The nonlinear optical crystal has no symmetrical center, belongs to an orthorhombic crystal system, and has a space group Ama2. The nonlinear optical crystal is an infrared nonlinear optical crystal, and has the advantages of great nonlinear optical effect, wide light transmitting band, high hardness, good mechanical properties, breakage resistance, deliquescence resistance, easiness in processing and preserving, etc. Also disclosed in the present invention are a method for preparing the nonlinear optical crystal and application thereof.

Abstract: A calcium metaborate birefringent crystal and a preparation method and use thereof, the crystal having a chemical formula of CaB2O4 and a molecular weight of 125.70, and belonging to the orthorhombic crystal system and space group Pbcn with unit-cell parameters a=11.60(4)?, b=4.28(8)?, c=6.21(6)?, and Z=4, wherein the calcium metaborate birefringent crystal is a negative biaxial crystal with a transmission range of 165-3400 nm and a birefringence between 0.09-0.36; the crystal is applicable to infrared-visible-ultraviolet-deep ultraviolet bands, and is grown by a melt method, a flux method, a Bridgman method or a heat exchange method; the crystal obtained by the method of the present invention is easy to grow and easy to process; and can be used for making polarizing beam-splitting prisms.

Abstract: A method for measuring concentrations of multiple gases by using an infrared band laser light includes: pumping Ho crystal by using a 1.9 ?m single thulium-doped solid-state laser to obtain a 2 ?m band near-infrared laser output; controlling a light-emitting angle of 2 ?m band laser light; allowing the 2 ?m laser light to enter a first measurement cell at a first emergent angle, and measuring a concentration of methane gas in the first measurement cell; generating and introducing the 3-5 ?m mid-infrared laser light into a second measurement cell to measure concentrations of ammonia gas and carbon monoxide in the second measurement cell; generating and introducing the 6-12 ?m far-infrared laser light into a third measurement cell to measure concentrations of carbon dioxide, acetylene, ethylene and ethane gas in the third measurement cell.

Abstract: A nonlinear optical crystal of guanidinium tetrafluoroborate has a chemical formula of [C(NH2)3]BF4 and a molecular weight of 146.89, belongs to the trigonal crystal system, has a space group of R3m; has lattice parameters of a=7.4634(10)?, b=7.4634(10)?, c=9.1216(19) (6)?, and Z=3; has an ultraviolet cutoff edge of 200 nm; and has a frequency-multiplication response that is 4-5 times that of the commercialized nonlinear optical crystal KDP. A hydrothermal method, a room-temperature solution method, an evaporation method or a solvothermal method is used to grow the crystal in a centimeter-scaled size. The crystal can produce frequency-doubling, frequency-tripling, frequency-quadrupling, frequency-quintupling or frequency-sextupling harmonic light output from the fundamental frequency light of 1064 nm generated by a Nd:YAG laser, and/or can produce ultraviolet and deep-ultraviolet frequency-multiplication light output below 200 nm.

Abstract: An insoluble transdermal microneedle patch, includes microneedles and a backing. The microneedles include bases and needlepoints located on the base, and materials made for the microneedles include crosslinked sodium alginate. The backing is connected with the bases, and parts of the backing corresponding to the needlepoints are hollow portions. The microneedle patch can act in the skin for a long time, during it is used for transdermal delivery, drugs can enter skin micropores to be absorbed into a body through pores formed after swelled microneedles acting on the skin absorbs water, thereby increasing a bioavailability of the drugs during the transdermal delivery. After drug administration end, the microneedles are completely removed without increasing a metabolic burden in the body, soluble materials are prevented from being accumulated in the body, and the microneedles have good biological safety. A preparation method of the insoluble transdermal microneedle patch and application thereof are provided.

Abstract: A method for preparing high-purity granatin A: by means of a combination of low-temperature liquid phase chromatography and an isomerization conversion purification method, using pomegranate peel extract as a source material, granatin A of over 98% purity can be acquired, and can be used as a standard product for quality control of pomegranate peel, pomegranate flower, or other medicinal material with granatin A as the active ingredient.

Abstract: A method for measuring multiple parameters of mixed gases based on broadband infrared light source is provided, including: filtering a broadband infrared laser, and forming a laser beam including three narrow-linewidth wavelengths; dividing the laser beam into a first sub-laser beam and a second sub-laser beam; focusing and transmitting the first sub-laser beam to a gas sample cell; focusing and transmitting the first sub-laser beam to a first reflector; reflecting and transmitting the first sub-laser beam; reflecting and transmitting the second sub-laser beam to the second beam splitter; combing the first sub-laser beam transmitted by the second beam splitter and the second sub-laser beam reflected by the second beam splitter, measuring the multiple parameters; combining and transmitting the second sub-laser beam transmitted by the second beam splitter and the first sub-laser beam reflected by the second beam splitter to a spectrometer for measuring concentrations the mixed gases.

Abstract: A fiber optic sensing head includes a single-mode optical fiber, a twin hole optical fiber including a cladding region and a core region surrounded by the cladding region, and the core region includes a second core located at an axis center, as well as a first and second round holes symmetrically distributed with respect to the second core; an incoming end of a gradient refractive-index fiber is connected to an outgoing end of the twin hole optical fiber with the incoming end of the gradient index fiber aligned with the outgoing end of the single-mode optical fiber at center. A thermal-sensitive structure is filled in a preset length part of the second round hole extending along an axial direction of the twin hole optical fiber. An incoming end of the twin hole optical fiber is connected to an outgoing end of the gradient index optical fiber with displacement.

Abstract: A method for preparing perovskite nanopowder through a rheological phase reaction at low-temperature that can include: taking hydroxide and metallorganic compound as initial reactants; mixing and stirring the reaction raw materials to form a solid-liquid rheological phase mixture; and controlling the reaction temperature and period, under a low-temperature condition, to prepare perovskite nanopowder in nearly spherical shape and a size of 20-100 nm. This allows for advantages such as controllable product size, low cost, high yield per unit volume, environmental friendliness, high yield per unit volume, and high repeatability. The perovskite nanopowder obtained by this way is nearly spherical, are uniform in size distribution and have controllable granularity. This can be used as the ceramic substrate for electronic components such as high-end chip capacitors and PTC thermistors, etc., as well as the raw material for manufacturing ceramic 3D printing additives and electronic ceramic ink.

Abstract: A compound strontium fluoroborate, nonlinear optical crystal of strontium fluoroborate, preparation method thereof; the chemical formula of the compound is SrB5O7F3, its molecular weight is 310.67, and it is prepared by solid-state reaction; the chemical formula of the crystal is SrB5O7F3, its molecular weight is 310.67, the crystal is of the orthorhombic series, the space group is Ccm21, and the crystal cell parameters are=10.016(6) ?, b=8.654(6)(4) ?, c=8.103(5) ?, Z=4, and V=702.4(8) ?3. A SrB5O7F3 nonlinear optical crystal has uses in the preparation of a harmonic light output when doubling, tripling, quadrupling, quintupling, or sextupling the frequency of a 1064-nm fundamental-frequency light outputted by a Nd:YAG laser, or the generation of a deep-ultraviolet frequency doubling light output lower than 200 nm, or in the preparation of a frequency multiplier, upper or lower frequency converter, or an optical parametric oscillator.

Abstract: An isomerization feature-based method for purifying and preparing punicalagin is provided, wherein pomegranate peel extract is used as a raw material. The isomerization feature-based method avoids impurities contained in the punicalagin based on structural characteristics, for example, the punicalagin in the pomegranate peel extract has two mutually convertible isomers. In the isomerization feature-based method, a pilot-scale preparative liquid chromatography is used to obtain a large amount of the punicalagin having a purity higher than 98% from a complex pomegranate peel extract. The isomerization feature-based method is simple, an obtained punicalagin has high purities and a preparation is in a massive scale. The isomerization feature-based has a strong reference value for purification and preparation of compounds with isomerization features.

Abstract: A nonlinear optical crystal of barium cesium borate, a preparation method and use thereof are provided. The nonlinear optical crystal has a chemical formula of CsBa3B11O20 and a molecular weight of 983.84. The nonlinear optical crystal belongs to an orthorhombic crystal system; a space group of the nonlinear optical crystal is Cmc21; lattice parameters of the nonlinear optical crystal are a=19.011(7) ?, b=10.837(4) ?, c=8.578(3) ?, Z=4, V=1767.4(11) ?3; and a Mohs hardness of the nonlinear optical crystal is 4-5. The nonlinear optical crystal is grown by a flux method. The nonlinear optical crystal of the barium cesium borate obtained is used for a manufacture of non-linear optical devices. The nonlinear optical crystal has a large size of centimeter-scale at least and is prepared by fast, simple and low-cost operations. The nonlinear optical crystal prepared has a large size, a wide light transmission band and good mechanical properties.

Abstract: The present invention discloses a hypocrellin derivative substituted both in a pen-position and in a 2-position by an amino, and a preparation method and use thereof. A general structural formula of the derivative is as represented by formulas I-a to I-d: The hypocrellin derivative substituted both in a peri-position and in a 2-position by an amino prepared in the present invention has a maximum absorption wavelength of 600-650 nm and a molar extinction coefficient reaching about 20000-40000 M?1cm?1. Compared with unmodified hypocrellin or hypocrellin having only a 2-position modified, an absorption spectrum of the derivative is significantly red-shifted and the molar extinction coefficient is greatly improved, and the derivative can efficiently produce reactive oxygen species such as singlet oxygen in a photosensitive condition.

Abstract: Disclosed in the present invention is a nonlinear optical crystal. The chemical formula of the nonlinear optical crystal is MHgGeSe4, M being selected from Ba or Sr. The nonlinear optical crystal has no symmetrical center, belongs to an orthorhombic crystal system, and has a space group Ama2. The nonlinear optical crystal is an infrared nonlinear optical crystal, and has the advantages of great nonlinear optical effect, wide light transmitting band, high hardness, good mechanical properties, breakage resistance, deliquescence resistance, easiness in processing and preserving, etc. Also disclosed in the present invention are a method for preparing the nonlinear optical crystal and application thereof.

Abstract: Disclosed in the present invention is a semiconductor laser, which includes one or more semiconductor chips (1-1), a total length of a gain region (1-11A) of a light-emitting unit (1-11) of each of the semiconductor chips (1-1) in a slow axis direction being 1 mm˜10 cm; a laser resonant cavity configured to adjust semiconductor laser emitted by the light-emitting unit (1-11) to resonate in the slow axis direction, so that the size of the gain region (1-11A) of the light-emitting unit (1-11) in the slow axis direction matches a fundamental mode spot radius ?0; and a fast-axis collimating element (FAC) disposed in the laser resonant cavity and configured to collimate the laser emitted by the light-emitting unit (1-11) in a fast axis direction. The semiconductor laser according to an embodiment of the present invention can improve the high-power output capability of the gain region on the one hand, and improve the beam quality on the other hand, which can achieve a high beam quality output of M2<2.

Abstract: The invention discloses a monosubstituted or polysubstituted amphiphilic hypocrellin derivative, and a preparation method and application thereof. The amphiphilic hypocrellin derivative substituted by a group containing PEG, a quaternary ammonium salt or the like prepared according to the invention has an obvious red shift in its absorption spectrum and a significantly enhanced molar extinction coefficient, compared with the parent hypocrellin, can efficiently produce singlet state oxygen and other reactive oxygen species under photosensitive conditions; has different amphiphilicities and increased biocompatibility with cells or tissues by regulating its hydrophilicity and hydrophobicity; can meet the requirements of different clinical drugs, and solves the requirements of different drug delivery methods for different drug hydrophilicity and lipophilicity.

Abstract: The present invention discloses a hypocrellin derivative substituted both in a peri-position and in a 2-position by an amino, and a preparation method and use thereof. A general structural formula of the derivative is as represented by formulas I-a to I-d: The hypocrellin derivative substituted both in a peri-position and in a 2-position by an amino prepared in the present invention has a maximum absorption wavelength of 600-650 nm and a molar extinction coefficient reaching about 20000-40000 M?1cm?1. Compared with unmodified hypocrellin or hypocrellin having only a 2-position modified, an absorption spectrum of the derivative is significantly red-shifted and the molar extinction coefficient is greatly improved, and the derivative can efficiently produce reactive oxygen species such as singlet oxygen in a photosensitive condition.

Abstract: Disclosed is a heat-sensitive processless planographic printing plate material containing a thermosensitive protection layer. The planographic printing plate material sequentially comprises a supporting body, a hydrophilic layer, a heat-sensitive layer and a thermosensitive protection layer from the bottom up. The thermosensitive protection layer therein can not only isolate oxygen and protect the heat-sensitive layer from oxygen inhibition, but can also sense heat and allow a polymerization reaction to take place. Thus the binding force between same and the next layer is improved, so that the precision of printing plate images is high, the development performance is good, and the pressrun is high.

Abstract: A low-temperature quick-freezing freeze-drying system provided by the invention includes: a compressor unit, a first heat exchanger, an air cooler, a second heat exchanger, a throttling element, a third heat exchanger, a circulating fan, a drying chamber, a third valve, a fourth valve and connecting pipelines, and the above elements form a refrigeration circulation loop, a quick freezing/freeze-drying circulation loop, and a desorption drying circulation loop, thereby realizing the low-temperature quick-freezing and freeze-drying of materials. The invention adopts the heat exchangers with a cold storage function, so that the refrigeration capacity of the compressor is stored and used intensively to achieve rapid cooling of the materials.