Abstract: A method of processing a query to a graph database using processors. The method comprises providing threads to be executed on processors, each the thread is associated with one of a plurality of unique thread identifiers, providing a graph database having a plurality of graph database nodes and a plurality of graph database edges, each the graph database edge represents a relationship between two of the plurality of graph database nodes, receiving a query tree that defines a tree comprising plurality of query nodes connected by a plurality of query tree edges, and searching at least part of the graph database for a match with the query tree, wherein the searching is executed by the processors, and wherein each processor searches one of a plurality of sub-graphs of the graph database, each the sub-graph is defined by one of the plurality of thread identifiers.

Abstract: A computing device, comprising at least one peripheral computing component, electrically connected to each of a plurality of hardware processors; wherein at least one of the plurality of hardware processors is adapted to executing a code for: configuring the at least one peripheral computing component to access at least one first memory location in a first memory component electrically coupled with a first hardware processor of the plurality of hardware processors via a first electrical connection between the peripheral computing component and the first hardware processor; and configuring the at least one peripheral computing component to access at least one second memory location in a second memory component electrically coupled with a second hardware processor of the plurality of hardware processors via a second electrical connection between the peripheral computing component and the second hardware processor; and wherein the first hardware processor is not the second hardware processor.

Abstract: A system for training a quantized neural network dataset, comprising at least one hardware processor adapted to: receive input data comprising a plurality of training input value sets and a plurality of target value sets; in each of a plurality of training iterations: for each layer, comprising a plurality of weight values, of one or more of a plurality of layers of a neural network: compute a set of transformed values by applying to a plurality of layer values one or more emulated non-uniformly quantized transformations by adding to each of the plurality of layer values one or more uniformly distributed random noise values; and compute a plurality of output values; compute a plurality of training output values; and update one or more of the plurality of weight values to decrease a value of a loss function; and output the updated plurality of weight values of the plurality of layers.

Abstract: A compact robotic device for driving movement of two or more elongate surgical tools configured for a telescopic arrangement when said two or more elongate surgical tools are at least partially received within said device, the device comprising: a housing comprising walls which define an inner volume including at least two inner pathways for accommodating the two or more elongate surgical tools; the housing encasing: a plurality of motors, and two or more tool actuation assemblies configured at a position of each of the two or more inner pathways; the actuation assemblies driven by the plurality of motors and configured to operably contact an elongate surgical tool at least partially received in the inner pathway to at least one of advance, retract and/or roll said elongate surgical tool.

Abstract: A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5? position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.

Abstract: A method for dielectrophoresis includes applying an electric field across a micro-fluidic chamber with an alternating current (AC), trapping the target particles on the at least one carrier particle, transporting the target particles from a first location in the chamber to a second location in the chamber distanced from the first location with the at least one carrier particle and dynamically controlling the trapping and the transporting based on remotely applying forces on the at least one carrier particle. The trapping is based on localized gradients of the electric field induced by the carrier particle. The applied electric field is uniform absent a carrier particle present in the micro-fluidic chamber. The micro-fluidic chamber contains an electrolyte-solution with suspended target particles and at least one carrier particle freely floating on or in the electrolyte-solution.

Abstract: A pharmaceutical composition and a method of treating, reducing or preventing vascular, cardiovascular arterial or valve calcification in a subject in need comprising administering to the subject an effective amount of an agent that prevents or reduces the expression of HDAC4, an agent that modulates the location of HDAC4, an agent that binds to HDAC4 or an inhibitor of HDAC4 or any combination thereof is provided. In some embodiments, there is provided a pharmaceutical composition comprising: an agent that prevents or reduces the expression of HDAC4, an agent that modulates the location of HDAC4, an agent that binds to HDAC4 or an inhibitor of HDAC4 or any combination thereof; an agent that prevents or reduces the expression of SIK or is an inhibitor of SIK; and/or an agent that prevents or reduces the expression of ENIGMA (Pdlim7) or is an inhibitor of ENIGMA.

Abstract: There is provided a method of representing a three dimensional (3D) object using univariate curves, comprising: receiving an initial definition of a 3D object representation, calculate a covering set of univariate curves, the covering set comprising at least one non-planar univariate curve, wherein the covering set of univariate curves represent the volume of the 3D object within a tolerance requirement, and generating a representation of the 3D object based on the set of univariate curves, wherein the set of univariate curves represent the volume of the 3D object.

Abstract: A method comprising acquiring a first image of a scene inside a medium, under illumination from a first location or orientation. The method comprises an action of acquiring a second image of the scene inside the medium, under illumination from a second, different location or orientation. The method comprises an action of computing attenuation coefficients, one per color channel, based on backscatter in the first and second images.

Abstract: Provided is a superabsorbent structure based on a covalently crosslinked copolymer having a microstructure of a HIPE, and characterized by hydrophobic and hydrophilic segments of at least five residues; the unique chemical and structural properties of the copolymer afford a polymeric superabsorbent structure that is capable of swelling in polar as well as apolar media. Also provided are processes of manufacturing the superabsorbent structure, and uses thereof.

Abstract: A method of expanding and maintaining human embryonic stem cells (ESCs) in an undifferentiated state by culturing the ESCs in a suspension culture under culturing conditions devoid of substrate adherence is provided. Also provided are a method of deriving ESC lines in the suspension culture and methods of generating lineage-specific cells from ESCs which were expanded in the suspension culture of the present invention.

Abstract: A method tor the preparation of a highly polarized nuclear spins containing sample of an organic or inorganic material, containing H or OH groups or adsorbed water molecules. Such highly polarized nuclear spins containing samples can be subjected to nuclear magnetic resonance (NMR) measurement and/or can be thawed and immediately administered to an individual undergoing a magnetic resonance imaging (MRI) scan. The method is based on generating unstable radicals on the surface of the sample in the presence of ionized environment followed by cooling the sample to cryogenic temperatures. A device for carrying out a particular step of said method is also discloses.

Abstract: A system and method to measure blood oxygenation levels and total hemoglobin on individually selected blood vessels, to provide a representation of the subject condition and of tissue perfusion that may be used for diagnosing specific tissue conditions. Reflection spectra from individual blood vessels or a collection of vessels are measured by using wide-field imaging for selecting target vessels and a narrow-field confocal detection system to enable measuring local blood oxygenation and hemoglobin. Optical fibers may be used to illuminate the target vessel and to detect light diffusively reflected therefrom. The reflection spectra may be analyzed in a spectrometer to extract the ratio of the deoxy- to oxyhemoglobin and to determine their absolute concentration for computing total hemoglobin levels. An alternative implementation uses image processing on camera images of a blood vessel, generated at an isosbestic wavelength of the deoxy- and oxyhemoglobin, and optionally also at neighboring wavelengths.

Abstract: A sensing device that may include a substrate; a single-ended SPAD; first electrical components; second electrical components; and capacitors. The SPAD, the first electrical components and the second electrical components are formed on the substrate. The SPAD and the first electrical components belong to a high voltage domain of the sensing device. The high voltage domain is configured to receive a high supply voltage that exceeds a breakdown voltage of the SPAD. The second electrical components belong to a low voltage domain of the sensing device. The capacitors are coupled between the low voltage domain and the high voltage domain. The first electrical components and the second electrical components belong to an electrical circuit that is configured to perform quenching of the SPAD.

Abstract: A composite comprised of: (i) at least one inverse freezing material, and (ii) an additive in the form of at least one solid particle. Articles made of the composites, and uses of the composites or the articles incorporating same, particularly for reducing incoming shockwaves, are also disclosed.

Abstract: An atmospheric moisture harvesting system, in which water vapor is separated from the air using a liquid desiccant subsystem. The moisture charged liquid desiccant enters a desorber and condensation system, where the moisture is extracted. Cooling and condensation are performed on the extracted water vapor only, thereby saving the energy for cooling air containing the water vapor, as is done in direct cooling systems. The system thus operates as a single stage vapor separation system since the vapor concentration remains in the liquid desiccant which is circulated to the separation and condensation subsystems without air laden with the moisture. Low grade or solar heat can be used as the energy source for the vapor desorption. A heat exchanger utilizes unwanted heat from regenerated desiccant to heat up charged desiccant entering the regenerating stage. The system has substantial energy savings over prior art systems using direct cooling of air.

Abstract: The invention provides compositions, kits and methods for depositing a composition comprising a plurality of magnetic particles, to a target site of a subject by delivering the composition via controlled inhalation to a region of the subject's respiratory tract and applying a magnetic field to a target site within the region of the subject's respiratory tract to capture the particles in said target site.

Abstract: A method for detecting a pattern of events, comprising: receiving a template defining the pattern of events to detect; producing a join query for a relational database from the template; selecting a cost function for the join query, wherein a computation cost of the join query is equivalent to a computation cost of matching between a plurality of events from a plurality of streams of events and the template; identifying a preferred plan for executing the join query according to a minimal value of the cost function; producing an ordered set of a plurality of patterns, according to the preferred plan, by converting a plurality of database operations of the preferred plan into the ordered set of the plurality of patterns; and using the ordered set as an input for detecting a plurality of matches between the plurality of patterns and the plurality of events.

Abstract: A system for generating cold plasma is presented, suitable for use in in-vivo treatment of biological tissue. The system comprising: a control unit connectable to an elongated member at a first proximal end of the elongated member. The elongated member comprises a plasma generating unit at a second distal end thereof and gas and electricity transmission channels extending from said first proximal end towards said plasma generating unit. The control unit comprises a gas supply unit configured to provide predetermined flow rate of selected gas composition through said gas transmission channel and a power supply unit configured to generate selected sequence of high-frequency electrical pulses, typically in mega Hertz range, directed through said electricity transmission channel, thereby providing power and gas of said selected composition to the plasma generating unit for generating cold plasma.

Abstract: A digital to analog converter is constructed using a neural network layer. The converter has inputs for receiving parallel bits of a digital input signal and an output for outputting an analog signal which is based on the digital input. Connecting the input and the output is a neural network layer which is configured to convert the parallel bits into an output analog signal that is representative of the digital input signal. The neural network may be hardwired and the synapses may rely on memristors as programmable elements.