Patents Assigned to Technion Research & Development Foundation Limited
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Publication number: 20230170909Abstract: A method of using memristor aided logic (MAGIC), comprises connecting together two input and one output memristor between a bit line and a word line, each memristor having a high resistance state and a low resistance state, setting the output memristor to the low resistance state as an initiation state and then applying logic inputs to the input memristors. The output then depends on whether the logic inputs have set the output memristor to the high resistance state.Type: ApplicationFiled: April 7, 2021Publication date: June 1, 2023Applicant: Technion Research & Development Foundation LimitedInventors: Shahar KVATINSKY, Barak HOFFER
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Publication number: 20230158208Abstract: A scaffold comprising electrospun decellularized ECM of an organ, wherein the decellularized ECM has a similar protein composition to native ECM of the organ. Methods of generating same are also disclosed as well as uses of same.Type: ApplicationFiled: January 23, 2023Publication date: May 25, 2023Applicant: Technion Research & Development Foundation LimitedInventors: Marcelle MACHLUF, Eyal ZUSSMAN, Limor BARUCH
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Patent number: 11653871Abstract: A method comprising: receiving a plurality of data segments each representing human cardiac activity; calculating, from each of said data segments, a first value representing a distribution of a heart rate variability (HRV) parameter; acquiring a signal representing cardiac activity in a patient; deriving a second value representing distribution of an HRV parameter in said signal; and indicating an atrial fibrillation (AF) event in said patient, when a difference between said first and second values is above a predetermined threshold.Type: GrantFiled: March 7, 2019Date of Patent: May 23, 2023Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Yael Yaniv, Noam Keidar, Yonatan Elul
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Publication number: 20230155590Abstract: An electronic memory block comprises phase change memory cells for memory storage and further phase change memory cells forming logic gates, to provide in-memory data processing.Type: ApplicationFiled: April 7, 2021Publication date: May 18, 2023Applicant: Technion Research & Development Foundation LimitedInventors: Shahar KVATINSKY, Barak HOFFER, Eilam YALON, Nicolas WAINSTEIN
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Patent number: 11646793Abstract: An electro-optic system, the electro-optic system that may include an input port that is configured to receive a bandpass signal that conveys information; wherein the bandpass signal is a radio frequency (RF) signal; an optical carrier source that is configured to generate an optical carrier signal having an optical carrier frequency; at least one electrical bias circuit that is configured to generate at least one electrical bias signal; an electro-optic modulation circuit that is linear at the optical field; a manipulator that is configured to (a) receive the at least one electrical bias signal and the bandpass signal, (b) generate, based on the at least one electrical bias signal and the bandpass signal, at least one modulating signal; wherein the electro-optic modulation circuit is configured to modulate the optical carrier by the at least one modulating signal to provide an output optical signal that comprises at least one optical pilot tone and at least one optical sideband that conveys the information.Type: GrantFiled: March 15, 2021Date of Patent: May 9, 2023Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITEDInventors: Moshe Nazarathy, Amos Agmon, Alexander Tolmachev
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Publication number: 20230134408Abstract: A process of preparing a conductive oxide interface is described herein, comprising contacting a surface of a first oxide with a plasma of a reducing gas to obtain a treated surface, and depositing a second oxide on the treated surface, thereby obtaining a conductive oxide interface between the first oxide and the second oxide. Further described herein are composites and articles of manufacture comprising same, the composites comprising a first oxide and second oxide, and an interface between the first oxide and second oxide which comprises a conductive oxide interface, wherein the conductive oxide interface comprises nitrogen atoms and/or the second oxide is in an amorphous form and the conductive oxide interface is characterized by a sheet resistance of no more than 105 omega/square.Type: ApplicationFiled: April 15, 2021Publication date: May 4, 2023Applicant: Technion Research & Development Foundation LimitedInventors: Lior KORNBLUM, Dana COHEN AZARZAR, Maria BASKIN, Yang LI
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Patent number: 11639369Abstract: The present invention is directed to a cyclic polypeptide having ubiquitin binding affinity (KD) of 0.1-100 nM. Further provided are methods for reducing deubiquitination activity of a cell, and for treating cancer in a subject in need thereof.Type: GrantFiled: June 6, 2019Date of Patent: May 2, 2023Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, THE UNIVERSITY OF TOKYOInventors: Ashraf Brik, Mickal Nawatha, Hiroaki Suga, Joseph Rogers
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Patent number: 11633434Abstract: Kits and composition comprising: (i) a thermo-responsive hydrogel characterized by a viscosity suitable for hardening after administration on a subject's skin; (ii) a bacterial growth medium; and optionally, (iii) a population of non-pathogenic viable bacteria, are provided. Methods for topically delivering a therapeutic or cosmeceutical agent such as for inhibiting or reducing growth of microorganisms on a subject's skin are further provided.Type: GrantFiled: September 6, 2018Date of Patent: April 25, 2023Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Boaz Mizrahi, Maayan Lufton
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Patent number: 11631035Abstract: Disclosed embodiments are a computing system and a computer-implemented method for distributed training of a machine learning model over a plurality of computing nodes, in a plurality of iterations, characterized by gradient gap based mitigation of the gradient staleness problem. The disclosed method evaluates the staleness of the gradient based on the difference in gradients between a central point, for example an iteration's common starting point, and the points reached by the respective computing node during one or more iterations, and aggregates the update steps from the plurality of computing nodes, while giving more weight to computing nodes having a lesser change in the gradient.Type: GrantFiled: November 5, 2020Date of Patent: April 18, 2023Assignee: Technion Research & Development Foundation LimitedInventors: Assaf Schuster, Saar Barkai, Ido Hakimi
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Patent number: 11630808Abstract: A method of applying proof of lottery to select block forgers in a blockchain, comprising performing the following at a certain one of a plurality of computing nodes connected to a blockchain network: (1) transmitting one or more of a plurality of participation transactions submitted by at least some of the plurality of computing nodes for participating in selection process conducted to select forgers from the plurality of computing nodes to forge blocks to be added to the blockchain; (2) determining a respective forger, during each selection process, by applying a selection function to an outcome of a hash function and a plurality of participation transactions extracted from a first subset of blocks preceding the respective block, the hash function is applied to a second subset of blocks preceding the respective block; and (3) forging the respective block in case the certain computing node is selected as the respective forger.Type: GrantFiled: May 3, 2021Date of Patent: April 18, 2023Assignee: Technion Research & Development Foundation LimitedInventor: Oded Shmueli
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Publication number: 20230113487Abstract: Conjugates of fibrinogen and a plurality of curable groups covalently attached thereto, and curable formulations comprising such conjugates, are provided. Also provided are three-dimensional objects (scaffolds) made of the conjugate or the curable formulation, for example, by additive manufacturing, and uses thereof in, for example, tissue healing and/or regeneration.Type: ApplicationFiled: October 7, 2022Publication date: April 13, 2023Applicant: Technion Research & Development Foundation LimitedInventors: Dror SELIKTAR, Haneen SIMAAN-YAMEEN
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Patent number: 11619543Abstract: Apparatus is provided including an acoustic sensor (50) having an optical waveguide (20). The optical waveguide (20) includes a waveguide core (202) having a waveguide core refractive index and a waveguide core photo-elastic coefficient, and an over-cladding layer (204) coupled to the waveguide core (202) and including an optically transparent polymer having an over-cladding refractive index and an over-cladding photo-elastic coefficient. The waveguide core refractive index is greater than the over-cladding refractive index, and the over-cladding photo-elastic coefficient is greater than the waveguide core photo-elastic coefficient. Other applications are also described.Type: GrantFiled: August 20, 2019Date of Patent: April 4, 2023Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Amir Rozental, Resmi Ravi Kumar, Shai Tsesses, Assaf Grinberg
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Patent number: 11620752Abstract: A method comprising: receiving an image of a scene, segmenting the image into a plurality of segments, obtaining at least one depth sample from each of at least some of the segments, and with respect to each of the at least some of the segments, assigning a value of the depth sample to each pixel in the segment, to create a depth image of the image.Type: GrantFiled: June 2, 2020Date of Patent: April 4, 2023Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Guy Gilboa, Adam Wolff, Shachar Praisler, Ilya Tcenov, Yossi Bar Erez
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Publication number: 20230095010Abstract: The invention provides a method for treating cancer comprising the step of administering a therapeutically effective amount of KPC1, a peptide which is at least about 70% homologous to the KPC1 or an agent which up-regulates KPC1. In some embodiments, there is also provided a method for treating cancer comprising the step of administering a therapeutically effective amount of p50, a peptide which is at least about 70% homologous to the p50 or an agent which up-regulates p50.Type: ApplicationFiled: August 15, 2022Publication date: March 30, 2023Applicant: Technion Research & Development Foundation Limited.Inventors: Aaron CIECHANOVER, Yelena KRAVTSOVA, Inna SHOMER, Victoria COHEN
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Patent number: 11611352Abstract: A digital to analog converter is constructed using a neural network layer. The converter has inputs for receiving parallel bits of a digital input signal and an output for outputting an analog signal which is based on the digital input. Connecting the input and the output is a neural network layer which is configured to convert the parallel bits into an output analog signal that is representative of the digital input signal. The neural network may be hardwired and the synapses may rely on memristors as programmable elements.Type: GrantFiled: July 11, 2018Date of Patent: March 21, 2023Assignee: Technion Research & Development Foundation LimitedInventors: Shahar Kvatinsky, Loai Danial
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Patent number: 11601602Abstract: A method comprising receiving data representing light intensity values corresponding to a flicker pattern of a reference light source powered by an alternating current (AC); operating a controllable illumination source, based, at least in part, on said data; capturing, using an imaging device, a sequence of images of a scene illuminated, at least in part, by said controllable illumination source; estimating an intensity value for at least one pixel in said array, correspondingly in each of said images in said sequence of images; and determining a temporal point in said flicker pattern of said reference light source, based, at least in part, on said estimating.Type: GrantFiled: June 20, 2019Date of Patent: March 7, 2023Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTOInventors: Mark Sheinin, Yoav Schechner, Yoash Levron, Kiriakos Neoklis Kutulakos
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Publication number: 20230061341Abstract: There is provided a method of computing lineage, comprising: managing a dataset of records, each record associated with set(s) of vectors of real numbers that encode an approximation of lineage of the respective record, the set(s) of vectors computed by an encoding process, obtaining result record(s) in response to executing a query on the dataset, computing set(s) of vectors for the result record(s), searching the set(s) of vectors on the records of the dataset to identify a record associated with a subset of vectors that are statistically similar to the set(s) of vectors for the result record(s), and providing a subset of the records corresponding to the identified subset of records, the subset of the records having a likelihood of contributing to the existence of the result record(s) in response to execution of the query.Type: ApplicationFiled: August 16, 2022Publication date: March 2, 2023Applicant: Technion Research & Development Foundation LimitedInventors: Oded SHMUELI, Michael LEYBOVICH
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Publication number: 20230060616Abstract: Well-defined, xeno-free culture media which comprise a TGF-beta isoform or the chimera formed between IL6 and the soluble IL6 receptor (IL6RIL6), which are capable of maintaining stem cells, and particularly, human embryonic stem cells, in an undifferentiated state are provided. Also provided are cell cultures comprising the culture media and the stem cells and methods of expanding and deriving embryonic stem cells in such well-defined, xeno-free culture media. In addition, the present invention provides methods of differentiating ESCs or EBs formed therefrom for the generation of lineage specific cells.Type: ApplicationFiled: October 24, 2022Publication date: March 2, 2023Applicant: Technion Research & Development Foundation LimitedInventors: Michal AMIT, Joseph ITSKOVITZ-ELDOR
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Patent number: 11591219Abstract: Compositions made of laminate comprised of porous carbon nanotube (CNT) are disclosed. Uses of the Compositions, particularly for reducing a formation of a load of a microorganism or of a biofilm, are also disclosed.Type: GrantFiled: February 22, 2018Date of Patent: February 28, 2023Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Carlos George Dosoretz, Avner Ronen, Chidambaram Thamaraiselvan, Sofia Lerman Roytblat
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Patent number: 11592542Abstract: An ultrasound detection device comprising: an ultrasound receiver configured to generate a signal indicative of a pressure of ultrasound that impinges on the receiver; and a coded mask comprising an ultrasound-blocking material perforated by an array of a plurality of apertures, the apertures arranged such that when the coded mask is placed over the receiver between the receiver and a source of ultrasound in a predetermined lateral position, the ultrasound is transmitted from the ultrasound source to the receiver via a known unique pattern of active apertures of the plurality of apertures such that the signal that is generated by the receiver is a multiplexed signal.Type: GrantFiled: September 24, 2020Date of Patent: February 28, 2023Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Amir Rozental, Evgeny Hahamovich