Abstract: A device for manipulating an object present in a fluid by electrokinetics is disclosed. The device comprises a substrate forming a flow chamber. The device further comprises a plurality of electrically biasable electrode structures and at least one electrically floating electrode structure.

Abstract: A novel group of aminoglycosides which share some structural features of currently available aminoglycosides with regard to the backbone, while also having significant structural differences, is disclosed. The similarity enables these aminoglycosides to be highly potent and effective antibiotics, while the significant differences enable these aminoglycosides to reduce or even block antibiotic resistance. The aminoglycosides of the present invention are suitable for inhibition of antrax lethal factor, hence are suitable for use as a cure for anthrax.

Abstract: A method for distributed computing includes processing multiple sets of data at respective computing nodes (24), and calculating respective local values of one or more statistical parameters characterizing the sets of the data. A global condition is defined, such that the condition is violated when a function defined over a weighted average of the respective local values crosses a predetermined threshold. The global condition is separated into a plurality of local constraints, which include a respective local constraint to be evaluated by each of the nodes based on the respective local values, such that violation of the respective local constraint in at least one of the nodes indicates a violation of the global condition. The local constraint is evaluated independently at each of the nodes. When at least one of the nodes detects that the respective local constraint is violated, an indication that the global condition has been violated is produced.

Abstract: Articles having a first substance, naturally having a first crystalline structure, confined between surfaces of a second substance having a second crystalline structure, whereby the first substance has a third (unusual) crystalline structure different from said first crystalline structure and methods of making same. Substances having unusual crystalline structures and methods of making same.

Abstract: A composition-of-matter comprising an antibody or antibody fragment including an antigen-binding region capable of specifically binding an antigen-presenting portion of a complex composed of a human antigen-presenting molecule and an antigen derived from a pathogen is disclosed.

Abstract: The present invention relates to methods for detecting alkylating agents in a sample using a chemosensor and measuring the change in measurable properties of chemosensor upon binding. Such changes provide indications of the presence and quantity of alkylating agent in the sample.

Abstract: Antibodies are provided. For as example, an antibody capable of binding an artificial receptor which comprises a hydroquinone monolayer and is incapable of binding the artificial receptor when comprising a benzoquinone monolayer. Also provided are methods and systems using same for control delivery of a molecule-of-interest into a tissue.

Abstract: A method and pharmaceutical compositions useful for inhibiting the growth of solid tumors (e.g., skin caner) are provided. Specifically, the method is effected by administering to a subject in need thereof an agent capable of upregulating the expression level and/or activity of at least a functional portion of Sef, wherein the functional portion being capable of inhibiting RTK-mediated cell proliferation and whereas upregulating can be effected by: expressing in cells of the subject an exogenous polynucleotide encoding at least a functional portion of Sef (e.g., SEQ ID NOs:4, 8 or 9); increasing expression of endogenous Sef in cells of the subject; increasing endogenous Sef activity in cells of the subject; and introducing an exogenous peptide and/or exogenous polypeptide including at least a functional portion of Sef to the subject. Also provided are methods and kits for diagnosing and staging of cancer (e.g.

Abstract: An ion concentration sensor produces a signal reflective of the ion concentration within a solution. The ion concentration sensor is based on an ion sensitive transistor having a solution input, a reference input, a diffusion input, and a diffusion output. The ion sensitive transistor is connected as a pass transistor, such that the diffusion output provides an electrical signal indicating an ion concentration in a solution contacting the solution input.

Abstract: Apparatus for obtaining 3-Dimensional data of a geometric body for matching, and particularly for use in facial matching, comprises a three dimensional scanner for obtaining three-dimensional topographical data of the body, a triangulator for receiving or forming said data into a triangulated manifold, a geodesic converter, for converting the triangulated manifold into a series of geodesic distances between pairs of points of the manifold, and a multi-dimensional scaler, for forming a low dimensional Euclidean representation of the series of geodesic distances, to give a bending invariant representation of the geometric body. In one variant, matching is carried out by taking the principle eigenvalues from the representation and plotting as co-ordinates in a feature space. Tilted or different expression versions of the same face tend to form clusters in the feature space allowing for matching. The apparatus preferably uses the fast marching method for the triangulated domain to obtain the geodesic distances.

Abstract: A method and device for identifying a molecule in a sample, the molecule comprising an electrophilic or nucleophilic moiety. The method comprises contacting the sample with a plurality of chemosensors, each of the chemosensors comprising a ?-conjugated system and a moiety having a nucleophilic property or an electrophilic property; and measuring an electromagnetic property of each of the chemosensors in the sample; whereby the pattern of changes in the electromagnetic properties of the plurality of chemosensors after chemically reacting with the electrophile or nucleophile of the molecule identifies the molecule in said sample.

Abstract: The present invention provides compounds of the general formula I, and uses thereof for printing electronic components such as wires, resistors and LEDs.

Abstract: A method to provide direct bonding of wires to silicon for microelectronic and micro-electromechanical systems (MEMS). The method includes preparing a rough “pothole” during one of the many deep etch steps already provided in MEMS fabrication. The method also includes roughening of the smooth silicon surface in and around the rough pothole and plastically deforming a ball-bond into the rough pothole, such that the interconnection will eliminate a costly metallization layer, and thereby lower fabrication expenses and allow high temperature processing.

Abstract: A method of generating embryoid bodies is provided. The method comprising culturing undifferentiated embryonic stem cells on a three dimensional scaffold under conditions suitable for formation of embryoid bodies, thereby generating the embryoid bodies.

Abstract: The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.

Abstract: A device for replenishing ionizable material in a field ionization apparatus is disclosed. The device comprises a heatable reservoir containing the ionizable material, a field ionization electrode structure, and a channel being in fluid communication with said heatable reservoir. The heatable reservoir and the channel are designed and constructed such that when the heatable reservoir is heated to an evaporation temperature of the ionizable material, a flux of vaporized ionizable material is directed along the channel to a tip of the field ionization electrode structure.

Abstract: A method of designing a transmissive optical element for converting a profile of a light beam from a predetermined input profile to a predetermined output profile is disclosed. The method comprises: calculating a stationary function of a predetermined cost functional selected such that the stationary function satisfies a mapping condition for mapping the predetermined input profile into the predetermined output profile, thereby providing a mapping function. The method further comprises utilizing the mapping function for calculating surface properties of at least a first surface and a second surface of the transmissive optical element.

Abstract: A space variant polarization optical element for spatially manipulating polarization-dependent geometrical phases of an incident light beam. The element comprises a substrate with a plurality of zones of gratings with a continuously varying orientation. The orientation denoted by ?(x-y) is equal to half of a desired geometrical phase (DGP) modulus 2?. Each grating has a local period that is smaller than the wavelength of the incident light beam. In other embodiments of the present invention the substrate comprises a plurality of zones of gratings with a continuously varying orientation.

Abstract: An isolated composition of matter is disclosed. The composition comprises a heterogeneous population of cells seeded on a scaffold, wherein the heterogeneous population of cells comprises cardiomyocytes, endothelial cells and fibroblast cells. Pharmaceutical compositions comprising same and uses thereof are also disclosed.

Abstract: An inverted ladder circuit for a Digital to Analog Converter (DAC) having an input binary word representing an input value and an output current corresponding to a converted analog value. The inverted ladder circuit includes at least two fine resistor ladders, including at least an upper fine resistor ladder and a lower fine resistor ladder. The inverted ladder circuit also includes a coarse resistor ladder having a corresponding plurality of coarse ladder resistors, wherein the coarse resistor ladder slides upon the at least two fine resistor ladders. The inverted ladder circuit also includes a plurality of upper fine switches and a plurality of lower fine switches, wherein the switches operate in parallel according to the lower five bits of the input binary word. The plurality of fine ladder resistors are matched with the plurality of coarse ladder resistors to obtain current proportional to the input binary word. The output resistance and parasitic capacitance are reduced.