Patents Assigned to Technion Research & Development Foundation
  • Patent number: 8026211
    Abstract: A method for increasing intestinal function is provided. The method comprising orally and/or enterally administering to a subject in need thereof a therapeutically effective amount of insulin, thereby increasing intestinal function.
    Type: Grant
    Filed: June 2, 2005
    Date of Patent: September 27, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Igor Sukhotnik, Naim Shehadeh, Raanan Shamir
  • Patent number: 8022190
    Abstract: An immuno-molecule which comprises a soluble human MHC class I effector domain; and an antibody targeting domain which is linked to the soluble human MHC class I effector domain, methods of making same and uses thereof.
    Type: Grant
    Filed: June 18, 2002
    Date of Patent: September 20, 2011
    Assignees: Technion Research & Development Foundation Ltd., Teva Pharmaceutical Industries Ltd.
    Inventors: Yoram Reiter, Avital Lev
  • Publication number: 20110209684
    Abstract: A sonic saturation system is provided that comprises at least one tank for containing a reservoir of liquid solvent; at least one gas-inlet in fluid communication with a gas compressor, for introducing gaseous solute into the reservoir, and at least one sonic agitator (146) for agitating the liquid reservoir thereby increasing the rate of impregnation of the solute into the solvent.
    Type: Application
    Filed: March 22, 2009
    Publication date: September 1, 2011
    Applicant: Technion-Research & Development Foundation Ltd
    Inventors: Mark Veinblat, Yoram Zvirin, Leonid Tartakovsky, Marcel Gutman, Vladimir Baibikov
  • Publication number: 20110204214
    Abstract: A light detection system is disclosed. The system comprises a light absorbing layer made of a semiconductor having majority carriers and minority carriers, and being incorporated with bandgap modifying atoms at a concentration selected so as to allow generation of photocurrent indicative of absorption of photons at any wavelength at least in the range of from about 3 ?m to about 5 ?m.
    Type: Application
    Filed: February 21, 2011
    Publication date: August 25, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Gad Bahir, Dan Fekete, Asaf Albo
  • Publication number: 20110204231
    Abstract: The current invention provides a method for improving the sensitivity of bolometric detection by providing improved electromagnetic power/energy absorption. In addition to its role in significantly improving the performance of conventional conducting-film bolometric detection elements, the method suggests application of plasmon resonance absorption for efficient thermal detection and imaging of far-field radiation using the Surface Plasmon Resonance (SPR) and the herein introduced Cavity Plasmone Resonance (CPR) phenomena. The latter offers detection characteristics, including good frequency sensitivity, intrinsic spatial (angular) selectivity without focusing lenses, wide tunability over both infrared and visible light domains, high responsivity and miniaturization capabilities. As compared to SPR, the CPR-type devices offer an increased flexibility over wide ranges of wavelengths, bandwidths, and device dimensions.
    Type: Application
    Filed: August 12, 2007
    Publication date: August 25, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Daniel Razansky, Pinchas Einziger, Dan Adam, Yael Nemirovsky, Lior Shwartzman
  • Patent number: 8004316
    Abstract: A complementary logic circuit contains a first logic input, a second logic input, a first dedicated logic terminal, a second dedicated logic terminal, a high-voltage terminal configured for connection to a high constant voltage a low-voltage terminal configured for connection to a low constant voltage, a p-type transistor, and an n-type transistor. The p-type transistor has an outer diffusion connection, a gate connection, an inner diffusion connection, and a bulk connection. The n-type transistor has an outer diffusion connection, a gate connection, an inner diffusion connection, and a bulk connection.
    Type: Grant
    Filed: February 1, 2006
    Date of Patent: August 23, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Alexander Fish, Arkadiy Morgenshtein
  • Patent number: 7977457
    Abstract: This invention provides fusion proteins comprising consecutive amino acids which beginning at the amino terminus of the protein correspond to consecutive amino acids present in (i) a cytomegalovirus human MHC-restricted peptide, (ii) a first peptide linker, (iii) a human ?-2 microglobulin, (iv) a second peptide linker, (v) a HLA-A2 chain of a human MHC class I molecule, (vi) a third peptide linker, (vii) a variable region from a heavy chain of a scFv fragment of an antibody, and (viii) a variable region from a light chain of such scFv fragment, wherein the consecutive amino acids which correspond to (vii) and (viii) are bound together directly by a peptide bond or by consecutive amino acids which correspond to a fourth peptide linker, wherein the antibody from which the scFv fragment is derived specifically binds to mesothelin. This invention provides nucleic acid constructs encoding same, processes for producing same, compositions, and uses thereof.
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: July 12, 2011
    Assignees: Teva Pharmaceutical Industries Ltd., Technion Research & Development Foundation Ltd.
    Inventors: Yoram Reiter, Roy Noy, Kfir Oved
  • Patent number: 7978316
    Abstract: An optical perturbation sensing system includes a probing beam incident on a medium with perturbations and a sensing beam redirected from the medium and incident on a surface area of a photodetector. A reference beam directed onto the photodetector surface forms, with the sensing beam, an interference pattern on the photodetector surface and a phase patterner with at least two phase regions across its section, generates different phases in different regions of the interference pattern. An array of photodetector elements detects each phase region of the interference pattern and a constructive combiner subtract pairs of the detected signals, squares the subtracted signal squares, and sums the squared signals to form a stronger detected signal with reduced intensity noise, reduced background noise, and reduced sensitivity to phase drifts.
    Type: Grant
    Filed: May 11, 2009
    Date of Patent: July 12, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventor: Avraham Aharoni
  • Publication number: 20110156019
    Abstract: Methods for producing p-doped organic semiconductor material with a fullerene derivative having at least one electron-withdrawing substituent covalently attached thereto, and semiconductor compositions prepared thereby are provided. Also provided are electronic devices, such as transistors, solar-cells, illuminating devices, OLEDs and detectors, comprised of these p-doped organic semiconductor materials.
    Type: Application
    Filed: September 9, 2009
    Publication date: June 30, 2011
    Applicant: Technion Research & Development Foundation, Ltd.
    Inventors: Nir Tessler, Olga Solomeshch
  • Publication number: 20110150874
    Abstract: This invention provides fusion proteins comprising consecutive amino acids which beginning at the amino terminus of the protein correspond to consecutive amino acids present in (i) a cytomegalovirus human MHC-restricted peptide, (ii) a first peptide linker, (iii) a human ?-2 microglobulin, (iv) a second peptide linker, (v) a HLA-A2 chain of a human MHC class I molecule, (vi) a third peptide linker, (vii) a variable region from a heavy chain of a scFv fragment of an antibody, and (viii) a variable region from a light chain of such scFv fragment, wherein the consecutive amino acids which correspond to (vii) and (viii) are bound together directly by a peptide bond or by consecutive amino acids which correspond to a fourth peptide linker, wherein the antibody from which the scFv fragment is derived specifically binds to mesothelin. This invention provides nucleic acid constructs encoding same, processes for producing same, compositions, and uses thereof.
    Type: Application
    Filed: December 20, 2010
    Publication date: June 23, 2011
    Applicants: Teva Pharmaceutical Industries Ltd., Technion Research & Development Foundation Ltd.
    Inventors: Yoram Reiter, Roy Noy, Kfir Oved
  • Patent number: 7964005
    Abstract: A composition that rapidly passivates copper-containing surface to yield a uniform layer of insoluble copper oxide, the composition being useful in chemical-mechanical planarization of copper-containing surfaces is disclosed. The composition is a solution having a pH of equal to or greater than 9 and having an oxidation potential sufficient to oxidize the surface to form non-soluble copper oxides. Also disclosed are methods of making and using the composition.
    Type: Grant
    Filed: April 4, 2004
    Date of Patent: June 21, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Yair Ein-Eli, David Starosvetsky, Esta Abelev, Eugene Rabkin
  • Publication number: 20110133088
    Abstract: A light detection system which comprises an active region between a back contact layer and a front contact layer is disclosed. The active region comprises a quantum well structure having a quantum well between quantum barriers, wherein the quantum well comprises foreign atoms that induce an excited bound state at an energy level which is above an energy level characterizing the quantum barriers.
    Type: Application
    Filed: August 19, 2010
    Publication date: June 9, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Asaf ALBO, Gad Bahir, Dan Fekete
  • Publication number: 20110136726
    Abstract: A novel class of antimicrobial polymeric agents which are designed to exert antimicrobial activity while being stable, non-toxic and avoiding development of resistance thereto and a process of preparing same are disclosed. Further disclosed are pharmaceutical compositions containing same and a method of treating medical conditions associated with pathological microorganisms, a medical device, an imaging probe and a food preservative utilizing same. Further disclosed are conjugates of an amino acid residue and a hydrophobic moiety residue and a process of preparing same.
    Type: Application
    Filed: February 21, 2011
    Publication date: June 9, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Amram MOR, Inna Radzishevsky
  • Patent number: 7955851
    Abstract: The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: June 7, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Michal Amit, Joseph Itskovitz-Eldor
  • Patent number: 7947499
    Abstract: The present invention is of a method of dynamically generating human embryoid bodies which can be used for generating lineage specific cells and cell lines. Specifically, the present invention can be used to generate ESC-differentiated cells for cell-replacement therapy.
    Type: Grant
    Filed: November 30, 2003
    Date of Patent: May 24, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Sharon Gerecht-Nir, Joseph Itskovitz-Eldor
  • Publication number: 20110117530
    Abstract: A method of simulating a formation of an incision or a deformation in a physical object. The method comprises spatially simulating a physical object in a simulation space using a volumetric arrangement of a plurality of prismatic elements, each the prismatic element having at least one adjustable parameter simulating a physical property of a respective segment of the physical object, measuring a movement of at least one simulation tool in the simulation space, selecting at least one of the plurality of prismatic elements according to the measurement, adjusting at least one adjustable parameter of at least one selected prismatic element according to the measurement, and spatially simulating an incision or deformation formed in the physical object in response to the movement using the adjusted volumetric arrangement.
    Type: Application
    Filed: May 7, 2010
    Publication date: May 19, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Dan ALBOCHER, Gershon Elber
  • Publication number: 20110105386
    Abstract: Methods and compositions for treating microbial infections associated with an emergence of resistance of a pathogenic microorganism to an antimicrobial agent, following treatment with antimicrobial agent are disclosed. The methods are effected by using a polymer which exhibits antimicrobial re-sensitizing activity, for re-sensitizing the pathogenic microorganisms to the antimicrobial agent, in combination with the antimicrobial agent. Further disclosed are novel polymers having an antimicrobial re-sensitizing activity.
    Type: Application
    Filed: January 15, 2009
    Publication date: May 5, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Amram Mor, Fadia Zaknoon, Shahar Rotem, Hadar Sarig
  • Publication number: 20110099205
    Abstract: In a data storage and retrieval system wherein data is stored and retrieved in pages, said data comprising connected nodes arranged such that each page stores only complete nodes, said connected nodes being connected via a plurality of overlapping tree structures, a method of minimizing page retrieval in the face of changing relationships between nodes comprising: selecting at least two of said overlapping tree structures; incrementally adjusting a page node structure dynamically based on real time workload, separately according to each selected tree structure, to form modified partitions for each tree structure, each modified partition being so as to minimize page faults; for each modified partition calculating a modification gain to indicate which partition has provided a greater minimization of page faults; and selecting the tree structure and modified partition corresponding to the best modification gain.
    Type: Application
    Filed: June 18, 2009
    Publication date: April 28, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Oded Shmueli, Lila Shnaiderman
  • Patent number: 7915223
    Abstract: A novel class of antimicrobial polymeric agents, which include a plurality of amino acid residues, such as positively charged amino acid residues, and at least one hydrophobic residue linking therebetween, such as an omega-amino-fatty acid residue, designed to exert antimicrobial activity while being stable, non-toxic and avoiding development of resistance thereto, and a process of preparing same, are disclosed. Further disclosed are pharmaceutical compositions containing same and a method of treating medical conditions associated with pathological microorganisms, a medical device, an imaging probe and a food preservative utilizing same. Further disclosed are conjugates of an amino acid residue and a hydrophobic moiety residue and a process of preparing same.
    Type: Grant
    Filed: August 8, 2006
    Date of Patent: March 29, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Amram Mor, Inna Radzishevsky
  • Publication number: 20110050859
    Abstract: A method of forming at least one three dimensional (3D) color image of at least one object in a target space. The method comprises projecting, each of a plurality of projection cycles, a sequence comprising a plurality of gray coded light patterns, each colored in one of red green or blue, on a target space, capturing a plurality of two dimensional (2D) images of the target space during a plurality of acquisition cycles, each the acquisition cycle being timed to correspond with the projection of at least a sub sequence of the sequence, the sub sequence comprising red, green, and blue gray coded light patterns of the plurality of gray coded light patterns, extracting range data and color texture information of at least one object in the target space from the plurality of 2D images, and forming a 3D color image of the range data and color texture information.
    Type: Application
    Filed: September 2, 2010
    Publication date: March 3, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Ron KIMMEL, Yaron HONEN