Abstract: A method for increasing intestinal function is provided. The method comprising orally and/or enterally administering to a subject in need thereof a therapeutically effective amount of insulin, thereby increasing intestinal function.
Type:
Grant
Filed:
June 2, 2005
Date of Patent:
September 27, 2011
Assignee:
Technion Research & Development Foundation Ltd.
Inventors:
Igor Sukhotnik, Naim Shehadeh, Raanan Shamir
Abstract: An immuno-molecule which comprises a soluble human MHC class I effector domain; and an antibody targeting domain which is linked to the soluble human MHC class I effector domain, methods of making same and uses thereof.
Type:
Grant
Filed:
June 18, 2002
Date of Patent:
September 20, 2011
Assignees:
Technion Research & Development Foundation Ltd., Teva Pharmaceutical Industries Ltd.
Abstract: A sonic saturation system is provided that comprises at least one tank for containing a reservoir of liquid solvent; at least one gas-inlet in fluid communication with a gas compressor, for introducing gaseous solute into the reservoir, and at least one sonic agitator (146) for agitating the liquid reservoir thereby increasing the rate of impregnation of the solute into the solvent.
Type:
Application
Filed:
March 22, 2009
Publication date:
September 1, 2011
Applicant:
Technion-Research & Development Foundation Ltd
Inventors:
Mark Veinblat, Yoram Zvirin, Leonid Tartakovsky, Marcel Gutman, Vladimir Baibikov
Abstract: A light detection system is disclosed. The system comprises a light absorbing layer made of a semiconductor having majority carriers and minority carriers, and being incorporated with bandgap modifying atoms at a concentration selected so as to allow generation of photocurrent indicative of absorption of photons at any wavelength at least in the range of from about 3 ?m to about 5 ?m.
Type:
Application
Filed:
February 21, 2011
Publication date:
August 25, 2011
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: The current invention provides a method for improving the sensitivity of bolometric detection by providing improved electromagnetic power/energy absorption. In addition to its role in significantly improving the performance of conventional conducting-film bolometric detection elements, the method suggests application of plasmon resonance absorption for efficient thermal detection and imaging of far-field radiation using the Surface Plasmon Resonance (SPR) and the herein introduced Cavity Plasmone Resonance (CPR) phenomena. The latter offers detection characteristics, including good frequency sensitivity, intrinsic spatial (angular) selectivity without focusing lenses, wide tunability over both infrared and visible light domains, high responsivity and miniaturization capabilities. As compared to SPR, the CPR-type devices offer an increased flexibility over wide ranges of wavelengths, bandwidths, and device dimensions.
Type:
Application
Filed:
August 12, 2007
Publication date:
August 25, 2011
Applicant:
Technion Research & Development Foundation Ltd.
Inventors:
Daniel Razansky, Pinchas Einziger, Dan Adam, Yael Nemirovsky, Lior Shwartzman
Abstract: A complementary logic circuit contains a first logic input, a second logic input, a first dedicated logic terminal, a second dedicated logic terminal, a high-voltage terminal configured for connection to a high constant voltage a low-voltage terminal configured for connection to a low constant voltage, a p-type transistor, and an n-type transistor. The p-type transistor has an outer diffusion connection, a gate connection, an inner diffusion connection, and a bulk connection. The n-type transistor has an outer diffusion connection, a gate connection, an inner diffusion connection, and a bulk connection.
Type:
Grant
Filed:
February 1, 2006
Date of Patent:
August 23, 2011
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: This invention provides fusion proteins comprising consecutive amino acids which beginning at the amino terminus of the protein correspond to consecutive amino acids present in (i) a cytomegalovirus human MHC-restricted peptide, (ii) a first peptide linker, (iii) a human ?-2 microglobulin, (iv) a second peptide linker, (v) a HLA-A2 chain of a human MHC class I molecule, (vi) a third peptide linker, (vii) a variable region from a heavy chain of a scFv fragment of an antibody, and (viii) a variable region from a light chain of such scFv fragment, wherein the consecutive amino acids which correspond to (vii) and (viii) are bound together directly by a peptide bond or by consecutive amino acids which correspond to a fourth peptide linker, wherein the antibody from which the scFv fragment is derived specifically binds to mesothelin. This invention provides nucleic acid constructs encoding same, processes for producing same, compositions, and uses thereof.
Type:
Grant
Filed:
May 17, 2007
Date of Patent:
July 12, 2011
Assignees:
Teva Pharmaceutical Industries Ltd., Technion Research & Development Foundation Ltd.
Abstract: An optical perturbation sensing system includes a probing beam incident on a medium with perturbations and a sensing beam redirected from the medium and incident on a surface area of a photodetector. A reference beam directed onto the photodetector surface forms, with the sensing beam, an interference pattern on the photodetector surface and a phase patterner with at least two phase regions across its section, generates different phases in different regions of the interference pattern. An array of photodetector elements detects each phase region of the interference pattern and a constructive combiner subtract pairs of the detected signals, squares the subtracted signal squares, and sums the squared signals to form a stronger detected signal with reduced intensity noise, reduced background noise, and reduced sensitivity to phase drifts.
Type:
Grant
Filed:
May 11, 2009
Date of Patent:
July 12, 2011
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: Methods for producing p-doped organic semiconductor material with a fullerene derivative having at least one electron-withdrawing substituent covalently attached thereto, and semiconductor compositions prepared thereby are provided. Also provided are electronic devices, such as transistors, solar-cells, illuminating devices, OLEDs and detectors, comprised of these p-doped organic semiconductor materials.
Type:
Application
Filed:
September 9, 2009
Publication date:
June 30, 2011
Applicant:
Technion Research & Development Foundation, Ltd.
Abstract: This invention provides fusion proteins comprising consecutive amino acids which beginning at the amino terminus of the protein correspond to consecutive amino acids present in (i) a cytomegalovirus human MHC-restricted peptide, (ii) a first peptide linker, (iii) a human ?-2 microglobulin, (iv) a second peptide linker, (v) a HLA-A2 chain of a human MHC class I molecule, (vi) a third peptide linker, (vii) a variable region from a heavy chain of a scFv fragment of an antibody, and (viii) a variable region from a light chain of such scFv fragment, wherein the consecutive amino acids which correspond to (vii) and (viii) are bound together directly by a peptide bond or by consecutive amino acids which correspond to a fourth peptide linker, wherein the antibody from which the scFv fragment is derived specifically binds to mesothelin. This invention provides nucleic acid constructs encoding same, processes for producing same, compositions, and uses thereof.
Type:
Application
Filed:
December 20, 2010
Publication date:
June 23, 2011
Applicants:
Teva Pharmaceutical Industries Ltd., Technion Research & Development Foundation Ltd.
Abstract: A composition that rapidly passivates copper-containing surface to yield a uniform layer of insoluble copper oxide, the composition being useful in chemical-mechanical planarization of copper-containing surfaces is disclosed. The composition is a solution having a pH of equal to or greater than 9 and having an oxidation potential sufficient to oxidize the surface to form non-soluble copper oxides. Also disclosed are methods of making and using the composition.
Type:
Grant
Filed:
April 4, 2004
Date of Patent:
June 21, 2011
Assignee:
Technion Research & Development Foundation Ltd.
Inventors:
Yair Ein-Eli, David Starosvetsky, Esta Abelev, Eugene Rabkin
Abstract: A light detection system which comprises an active region between a back contact layer and a front contact layer is disclosed. The active region comprises a quantum well structure having a quantum well between quantum barriers, wherein the quantum well comprises foreign atoms that induce an excited bound state at an energy level which is above an energy level characterizing the quantum barriers.
Type:
Application
Filed:
August 19, 2010
Publication date:
June 9, 2011
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: A novel class of antimicrobial polymeric agents which are designed to exert antimicrobial activity while being stable, non-toxic and avoiding development of resistance thereto and a process of preparing same are disclosed. Further disclosed are pharmaceutical compositions containing same and a method of treating medical conditions associated with pathological microorganisms, a medical device, an imaging probe and a food preservative utilizing same. Further disclosed are conjugates of an amino acid residue and a hydrophobic moiety residue and a process of preparing same.
Type:
Application
Filed:
February 21, 2011
Publication date:
June 9, 2011
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.
Type:
Grant
Filed:
September 21, 2009
Date of Patent:
June 7, 2011
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: The present invention is of a method of dynamically generating human embryoid bodies which can be used for generating lineage specific cells and cell lines. Specifically, the present invention can be used to generate ESC-differentiated cells for cell-replacement therapy.
Type:
Grant
Filed:
November 30, 2003
Date of Patent:
May 24, 2011
Assignee:
Technion Research & Development Foundation Ltd.
Inventors:
Sharon Gerecht-Nir, Joseph Itskovitz-Eldor
Abstract: A method of simulating a formation of an incision or a deformation in a physical object. The method comprises spatially simulating a physical object in a simulation space using a volumetric arrangement of a plurality of prismatic elements, each the prismatic element having at least one adjustable parameter simulating a physical property of a respective segment of the physical object, measuring a movement of at least one simulation tool in the simulation space, selecting at least one of the plurality of prismatic elements according to the measurement, adjusting at least one adjustable parameter of at least one selected prismatic element according to the measurement, and spatially simulating an incision or deformation formed in the physical object in response to the movement using the adjusted volumetric arrangement.
Type:
Application
Filed:
May 7, 2010
Publication date:
May 19, 2011
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: Methods and compositions for treating microbial infections associated with an emergence of resistance of a pathogenic microorganism to an antimicrobial agent, following treatment with antimicrobial agent are disclosed. The methods are effected by using a polymer which exhibits antimicrobial re-sensitizing activity, for re-sensitizing the pathogenic microorganisms to the antimicrobial agent, in combination with the antimicrobial agent. Further disclosed are novel polymers having an antimicrobial re-sensitizing activity.
Type:
Application
Filed:
January 15, 2009
Publication date:
May 5, 2011
Applicant:
Technion Research & Development Foundation Ltd.
Inventors:
Amram Mor, Fadia Zaknoon, Shahar Rotem, Hadar Sarig
Abstract: In a data storage and retrieval system wherein data is stored and retrieved in pages, said data comprising connected nodes arranged such that each page stores only complete nodes, said connected nodes being connected via a plurality of overlapping tree structures, a method of minimizing page retrieval in the face of changing relationships between nodes comprising: selecting at least two of said overlapping tree structures; incrementally adjusting a page node structure dynamically based on real time workload, separately according to each selected tree structure, to form modified partitions for each tree structure, each modified partition being so as to minimize page faults; for each modified partition calculating a modification gain to indicate which partition has provided a greater minimization of page faults; and selecting the tree structure and modified partition corresponding to the best modification gain.
Type:
Application
Filed:
June 18, 2009
Publication date:
April 28, 2011
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: A novel class of antimicrobial polymeric agents, which include a plurality of amino acid residues, such as positively charged amino acid residues, and at least one hydrophobic residue linking therebetween, such as an omega-amino-fatty acid residue, designed to exert antimicrobial activity while being stable, non-toxic and avoiding development of resistance thereto, and a process of preparing same, are disclosed. Further disclosed are pharmaceutical compositions containing same and a method of treating medical conditions associated with pathological microorganisms, a medical device, an imaging probe and a food preservative utilizing same. Further disclosed are conjugates of an amino acid residue and a hydrophobic moiety residue and a process of preparing same.
Type:
Grant
Filed:
August 8, 2006
Date of Patent:
March 29, 2011
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: A method of forming at least one three dimensional (3D) color image of at least one object in a target space. The method comprises projecting, each of a plurality of projection cycles, a sequence comprising a plurality of gray coded light patterns, each colored in one of red green or blue, on a target space, capturing a plurality of two dimensional (2D) images of the target space during a plurality of acquisition cycles, each the acquisition cycle being timed to correspond with the projection of at least a sub sequence of the sequence, the sub sequence comprising red, green, and blue gray coded light patterns of the plurality of gray coded light patterns, extracting range data and color texture information of at least one object in the target space from the plurality of 2D images, and forming a 3D color image of the range data and color texture information.
Type:
Application
Filed:
September 2, 2010
Publication date:
March 3, 2011
Applicant:
Technion Research & Development Foundation Ltd.