Abstract: A compliant transmission system includes a rotatable wave generator and a sleeve fitted on the wave generator. The rotatable wave generator has an external surface including pattern extending both annularly and in a longitudinal direction. The sleeve is configured to be deformable and to be impressed on its outer surface with waves extending along the longitudinal direction during rotation of the pattern of the wave generator within the sleeve.
Type:
Grant
Filed:
September 6, 2020
Date of Patent:
April 16, 2024
Assignee:
Technion Research & Development Foundation Limited
Abstract: The present invention relates to functional taste-improving composition comprising at least one taste-modifying protein (TMP), e.g., a sweet protein (SP) and at least one micropatching (MP) agent; and to uses thereof in the food and beverage industry.
Type:
Application
Filed:
December 30, 2021
Publication date:
April 11, 2024
Applicants:
AMAI PROTEINS LTD., TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Inventors:
Ilan SAMISH, Inbar ZUKER, Shmuel MARKO, Yoav LIVNEY, Evgeniya GOLDMAN, Ravit EDELMAN, Prerna Balkrishna PAWAR, Samaa ALASIBI
Abstract: A method comprising: at a training stage, training a machine learning algorithm on a training set comprising: (i) Heart Rate Variability (HRV) parameters extracted from temporal beat activity samples, wherein at least some of said samples include a representation of a Ventricular Fibrillation (VF) event, (ii) labels associated with one of: a first period of time immediately preceding a VF event in a temporal beat activity sample, a second period of time immediately preceding the first period of time in a temporal beat activity sample, and all other periods of time in a temporal beat activity sample; at an inference stage, receiving, as input, a target HRV parameters representing temporal beat activity in a subject; and applying said machine learning algorithm to said target HRV parameters, to predict an onset time of a VF event in said subject.
Type:
Grant
Filed:
September 5, 2019
Date of Patent:
April 2, 2024
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Inventors:
Yael Yaniv, Noam Keidar, Gal Eidelsztein, Alex Bronstein
Abstract: A method for estimating an information unit represented by DNA strands, the method includes (a) sequencing the DNA strands to provide noisy copies of an encoded version of the information unit; wherein the information unit comprises information unit elements; (b) neural network (NN) processing the multiple noisy copies by one or more NNs to provide a soft estimate of the encoded information unit; wherein the soft estimate comprises estimated encoded information unit elements and an encoded information unit elements estimated confidence parameter; and (c) decoding the soft estimate of the encoded information unit to provide a prediction of the information unit.
Type:
Application
Filed:
August 14, 2023
Publication date:
March 21, 2024
Applicants:
Technion Research & Development Foundation Limited, BAR-ILAN UNIVERSITY
Abstract: The present invention provides a nanoparticle including: (a) an amphiphilic co-polymer including an ionizable polymer covalently bound to a hydrophobic domain; and a polynucleotide comprising 60 to 500 nucleobases. Further provided are compositions including the nanoparticle of the invention, and methods of using same.
Type:
Application
Filed:
January 20, 2022
Publication date:
March 21, 2024
Applicants:
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD., TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: Embodiments of the invention relate to a corrole according to formula [I]; wherein R1, R2, and R3 are each independently H, —COOH, CF3, or a halide selected from the group consisting of F—, Cl—, Br— and I, with the proviso that R1, R2, and R3 can not all be CF3, and when the compound is of Formula II, wherein M is a metallic ion or an elemental ion selected from the group consisting of an elemental ion of group 13-16 in row 3 or above and boron, preferably selected from the group consisting of: Fe, Mn, Ga, P, Mo, Re, Co and Cu, or a salt thereof. Methods for treatment, catalysis, and detection using the compounds are also described.
Type:
Application
Filed:
January 11, 2022
Publication date:
March 14, 2024
Applicant:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD
Abstract: A method for converting heat to mechanical work including providing incoming heat transfer fluid (HTF) at a first temperature to a mixing chamber, providing incoming compressed gas at a second temperature to the mixing chamber, enabling the gas and the HTF to mix, producing a gas-and-HTF mix, enabling the HTF in the gas-and-HTF mix to heat the gas and isothermal expansion of the gas in the gas-and-HTF mix, limiting volume of the gas-and-HTF mix, thereby increasing pressure of the gas and causing acceleration of a flow of the gas-and-HTF mix, causing the gas-and-HTF mix to eject through a nozzle, thereby converting the heat of the HTF to kinetic energy, and using the kinetic energy to produce mechanical work. Related apparatus and methods are also described.
Type:
Grant
Filed:
August 30, 2021
Date of Patent:
March 12, 2024
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: Polymeric ion conductors composed of a polymeric or co-polymeric backbone which comprises a plurality of backbone units, a metal ligand attached to at least a portion of the backbone units, and a metal ion attached to the metal ligand are provided. The metal ligand can be an N-heterocyclic carbene ligand and the metal can feature low oxophilicity. lonomeric materials, including, for example, ion exchange membranes such as anion exchange membranes, made of the polymeric ion conductor, and electrochemical systems and articles-of-manufacturing containing the polymeric ion conductor or the ion exchange membrane are also provided.
Type:
Application
Filed:
December 31, 2021
Publication date:
March 7, 2024
Applicant:
Technion Research & Development Foundation Limited
Inventors:
Charles Eliezer DIESENDRUCK, Dario R. DEKEL
Abstract: An aspect of some embodiments of the invention relates to methods of manufacturing a 3D printed implant, comprising printing a mold of a scaffold, generating said scaffold from said mold, seeding cells on said scaffold, where said generating said scaffold comprises generating parts of said scaffold with different levels of stiffness.
Type:
Application
Filed:
January 4, 2022
Publication date:
February 29, 2024
Applicants:
Technion Research & Development Foundation Limited, Tel HaShomer Medical Research Infrastructure and Services Ltd.
Abstract: A self-healing field-effect transistor (FET) device is disclosed in this application, the self-healing FET has a self-healing substrate, a self-healing dielectric layer, a gate electrode, at least one source electrode, at least one drain electrode, and at least one channel. The self-healing substrate and the self-healing dielectric layer have a disulfide-containing poly(urea-urethane) (PUU) polymer. The self-healing dielectric layer has a thickness of less than about 10 ?m. The electrodes have electrically conductive elongated nanostructures. The at least one channel has semi-conducting elongated nanostructures.
Type:
Grant
Filed:
December 17, 2022
Date of Patent:
February 27, 2024
Assignee:
TECHNION RESEARCH AND
DEVELOPMENT FOUNDATION LTD.
Abstract: Provided are methods for diagnosing or selecting a mammal in need of a stimulant ADHD drug, conducting a non-specific electro-dermal responses (EDAs) analysis and/or an auditory sustained attention (ASAT) analysis on the mammal and administering or adjusting the dose of a stimulant ADHD drug to be administered to the mammal.
Type:
Grant
Filed:
August 15, 2019
Date of Patent:
February 27, 2024
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: Provided herein is a porous ?-cyclodextrin-containing monolith having a microstructure templated by the external phase of a HIPE, as well as processes of manufacturing the same and uses thereof.
Type:
Grant
Filed:
August 2, 2021
Date of Patent:
February 27, 2024
Assignee:
Technion Research & Development Foundation Limited
Inventors:
Rajashekharayya A. Sanguramath, Inna Berezovska, Michael S. Silverstein
Abstract: Compositions comprising electrospun fibers and colorimetric detection encapsulated thereto are provided. Further, methods of use of said composition, including, but not limited to in-situ detection of molecules of interest, such as explosive compounds, are provided.
Type:
Grant
Filed:
October 19, 2020
Date of Patent:
February 20, 2024
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
Abstract: A method for reconstructing spatial information, the method includes: (i) Obtaining an under-sampled frequency domain representation (FDR) of the spatial information. The under-sampled FDR was obtained by sampling an FDR of the spatial information with a sampling mask. (ii) Feeding the under-sampled FDR and the sampling mask to a machine learning process. (iii) Reconstructing the spatial information by the machine learning process. The machine learning process was trained using a training data set that includes training under-sampled FRDs of training spatial information, and one or more training sampling masks that were used to sample FDRs of training spatial information.
Type:
Application
Filed:
August 14, 2023
Publication date:
February 15, 2024
Applicant:
Technion Research & Development Foundation Limited
Abstract: An assembly for driving movement of an elongate surgical tool, comprising: a plurality of adjacent pairs of driving wheels, each pair of driving wheels having a space therebetween such that spaces of the plurality of pairs of driving wheels are axially aligned to form a channel for the elongate surgical tool to extend through; wherein at least one pair of driving wheels out of the plurality of pairs is arranged to lie on a plane different than a plane on which at least one other pair of driving wheels lies.
Type:
Application
Filed:
October 19, 2023
Publication date:
February 8, 2024
Applicants:
Microbot Medical Ltd., Technion Research & Development Foundation Limited
Inventors:
Simon SHARON, Idan BOADER, Evgeny KOFMAN, Zev SOHN, Moshe SHOHAM, Eran COHEN, Eyal MORAG
Abstract: A surface-emitting light source system for generating coherent light having two spin modes comprises a two-dimensional material exhibiting a direct band gap. The two-dimensional material is coupled to a planar heterostructure cavity having an inversion asymmetric core region at least partially surrounded by an inversion symmetric cladding region.
Type:
Application
Filed:
July 27, 2023
Publication date:
February 1, 2024
Applicant:
Technion Research & Development Foundation Limited
Abstract: Compositions comprising a tetraaryl ammonium salt, a tetraaryl ammonium salt covalently bound to a polymer and methods for manufacturing the same are disclosed. The disclosed compositions are useful e.g., for an anion exchange membrane, or an anion conducting polymer, and may further be used in electrochemical devices such as alkaline fuel cells, and alkaline redox-flow batteries.
Type:
Grant
Filed:
August 29, 2019
Date of Patent:
January 30, 2024
Assignee:
Technion Research & Development Foundation Limited
Inventors:
Charles Eliezer Diesendruck, Dario Dekel
Abstract: A system for generating light, comprises a spectral light source, characterized by a spectral line shape described by a visibility function; and a multimode waveguide, characterized by an optical path difference distribution described by a standard deviation. The standard deviation typically matches, within a predetermined tolerance, a location of a zero point of the visibility function at which a contrast of the visibility function is less than 0.1.
Type:
Grant
Filed:
April 16, 2021
Date of Patent:
January 23, 2024
Assignee:
Technion Research & Development Foundation Limited
Inventors:
Carmel Rotschild, Daria Negri, Michal Shimanovich, Matej Kurtulik
Abstract: A method of analyzing the therapeutic efficacy of a therapeutic agent for treating an immune-related disorder is disclosed. The method comprises contacting blood cells of the subject with the agent, measuring the expression of at least 20 genes in the blood cells of the subject; obtaining an immune age value based on the expression of the at least 20 genes, and comparing the immune age value with an immune age value of the subject calculated on the basis of expression of the at least 20 genes in blood cells of the subject, in the absence of the agent.
Type:
Application
Filed:
October 26, 2021
Publication date:
January 18, 2024
Applicants:
Technion Research & Development Foundation Limited, Rambam Med-Tech Ltd.
Inventors:
Shai S. SHEN-ORR, Yehuda CHOWERS, Ayelet ALPERT, Shiran GERASSY-VAINBERG, Erik FELDMAN
Abstract: A system comprising: at least one hardware processor; and a non-transitory computer-readable storage medium having stored thereon program instructions, the program instructions executable by the at least one hardware processor to: receive a data stream representing events; receive a plurality of complex event patterns (CEPs) comprising (a) a set of conditions reflecting relations among said events, and (b) a set of attributes associated with each of said events; and calculate an optimal multi-pattern evaluation plan corresponding to said CEPs by: (i) generating an initial evaluation plan, (ii) applying a search method to calculate modified versions of said initial evaluation plan, (iii) assigning a score to each of said modified versions based on a cost function, and (iv) selecting one of said modified versions having a highest said score as said optimal multi-pattern evaluation plan.
Type:
Grant
Filed:
January 7, 2020
Date of Patent:
January 16, 2024
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED