Abstract: Compositions comprising liposomes composed of whole cell membrane fraction are provided. The liposomes may be attached to, or encapsulate a pharmaceutical agent. Also provided are methods of generating and using these lipospmes.
Type:
Application
Filed:
August 26, 2010
Publication date:
June 28, 2012
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: A system for measuring one or more characteristics of light of a photon energy Eph from a light source, that can be determined from measuring three-photon absorption events, the system comprising: a) a detector having a band gap material characterized by gap energy between 2.1 and 3 times Eph; b) an optical element configured to concentrate a beam of light from the light source on the detector; c) a signal amplifier that amplifies an output signal indicative of when three photons produced by the light source undergo a three-photon absorption event in the band gap material; and d) an analyzer that analyzes the output signal to count or measure a rate of the three-photon absorption events, and determines the one or more characteristics of the light from the light source.
Type:
Application
Filed:
December 28, 2011
Publication date:
June 28, 2012
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: A method of separating a mixture of a plurality of molecular analytes having different isoelectric points (pIs). The method comprises placing a solution containing a mixture of a plurality of molecular analytes in a separation volume, generating a pH profile having a plurality of pH zones across an axis of the separation volume, and adjusting a profile of the pH profile to induce a migration of a first molecular analyte along the axis apart from a second molecular analyte. The first and second molecular analytes having different pIs.
Type:
Application
Filed:
August 18, 2010
Publication date:
June 14, 2012
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: Provided are methods of isolating pericyte progenitor cells from pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells, by isolating CD105+, CD73+ and/or CD105+/CD73+ cells from embryoid bodies and optionally by enriching the cells with CD31? cells. Also provided are methods of isolating endothelial cells and co-derivation of pericyte and endothelial cells progenitor cells from embryoid bodies, and methods of differentiating same for various therapeutic applications. In addition, the invention provides an isolated pericyte progenitor cell having an expression marker signature of CD105+/CD73+CD31?/alpha SMA?/CD133?/Flk-1?.
Type:
Application
Filed:
August 17, 2010
Publication date:
June 14, 2012
Applicant:
Technion Research & Development Foundation Ltd.
Inventors:
Ayelet Dar-Oaknin, Joseph Itskovitz-Eldor
Abstract: A device for isoelectric focusing. The device comprises a focusing container configured to contain an electrolyte solution and having a longitudinal axis and at least one electrolysis unit mounted in a close proximity to the longitudinal axis. Each electrolysis unit injects an ion flow into the focusing container so as to create a pH gradient having a plurality of steps in the electrolyte solution, along the longitudinal axis. Each step has a substantially uniform pH level and the pH gradient is defined by at least one pH ramp between every two sequential steps of the plurality of steps.
Type:
Application
Filed:
August 18, 2010
Publication date:
June 7, 2012
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: Disclosed is a novel family of macrocyclic compounds, coined calixurenes, which comprises linear and cyclic oligomers composed of alternating moieties of an aromatic unit and a ureatic unit, linked to one another via a bridging moiety. The disclosed calixurenes feature multiple heteroatom-containing groups, and can be designed so as to feature other functionalities, and can thus be used in a variety of applications. Further disclosed are processes of preparing the calixurenes, articles containing same and uses thereof.
Type:
Application
Filed:
August 12, 2010
Publication date:
June 7, 2012
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: A complementary logic circuit contains a first logic input, a second logic input, a first dedicated logic terminal, a second dedicated logic terminal, a high-voltage terminal configured for connection to a high constant voltage a low-voltage terminal configured for connection to a low constant voltage, a p-type transistor, and an n-type transistor. The p-type transistor has an outer diffusion connection, a gate connection, an inner diffusion connection, and a bulk connection. The n-type transistor has an outer diffusion connection, a gate connection, an inner diffusion connection, and a bulk connection.
Type:
Grant
Filed:
July 7, 2011
Date of Patent:
May 29, 2012
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: A complementary logic circuit, comprising: a first and second logic input; a first and second dedicated logic terminal; a p-type transistor network comprising multiple p-type transistors, for implementing a predetermined logic function, and having an outer diffusion connection connected to the first dedicated logic terminal, a first network gate connection connected to the first logic input, and an inner diffusion connection; and an n-type transistor network comprising multiple n-type transistors, for implementing a logic function complementary to the predetermined logic function, and having an outer diffusion connection connected to the second dedicated logic terminal, a first network gate connection connected to the second logic input, and an inner diffusion connection; the inner diffusion connections of the p-type transistor network and of the n-type transistor network being connected to form a common diffusion logic terminal.
Type:
Application
Filed:
February 2, 2012
Publication date:
May 24, 2012
Applicant:
Technion Research & Development Foundation Ltd.
Inventors:
Arkadiy MORGENSHTEIN, Alexander Fish, Israel A. Wagner
Abstract: A computerized method of mapping a plurality of model fragments covering a selected object. The method comprises receiving a representation of an object, generating a parameterized data model of the object according to said representation, the parameterized data model having a plurality of elements, setting a plurality of model fragments each cover a portion of the parameterized data model, applying, using a processor, a set cover algorithm to identify a subgroup of the plurality of model fragments so that a union of a plurality of members of the subgroup covers said parameterized data model, and outputting the subgroup.
Type:
Application
Filed:
November 17, 2011
Publication date:
May 24, 2012
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: Methods and compositions suitable for modulating angiogenesis in a mammalian tissue are provided. Further provided are methods suitable for inhibiting metastasis and fibrosis in a mammalian tissue and for assessing the malignancy of colon cancer tumors.
Type:
Grant
Filed:
September 30, 2009
Date of Patent:
May 1, 2012
Assignee:
Technion Research & Development Foundation Ltd.
Inventors:
Gera Neufeld, Gal Akiri, Zahava Vadasz, Stela Gengrinovitch
Abstract: Methods and compositions suitable for modulating angiogenesis in a mammalian tissue are provided. Further provided are methods suitable for inhibiting metastasis and fibrosis in a mammalian tissue and for assessing the malignancy of colon cancer tumors.
Type:
Grant
Filed:
November 27, 2003
Date of Patent:
April 24, 2012
Assignee:
Technion Research & Development Foundation Ltd.
Inventors:
Gera Neufeld, Gal Akiri, Zahava Vadasz, Stela Gengrinovitch
Abstract: A complementary logic circuit contains a first logic input, a second logic input, a first dedicated logic terminal, a second dedicated logic terminal, a first logic block, and a second logic block. The first logic block consists of a network of p-type transistors for implementing a predetermined logic function. The p-type transistor network has an outer diffusion connection, a first network gate connection, and an inner diffusion connection. The outer diffusion connection of the p-type transistor network is connected to the first dedicated logic terminal, and the first network gate connection of the p-type transistor network is connected to the first logic input. The second logic block consists of a network of n-type transistors which implements a logic function complementary to the logic function implemented by the first logic block. The n-type transistor network has an outer diffusion connection, a first network gate connection, and an inner diffusion connection.
Type:
Grant
Filed:
April 12, 2010
Date of Patent:
April 17, 2012
Assignee:
Technion Research & Development Foundation Ltd.
Inventors:
Arkadiy Morgenshtein, Alexander Fish, Israel A. Wagner
Abstract: A method of cropping a representation of a face for electronic processing, said method comprising: selecting a first geodesic contour about an invariant reference point on said face, setting a region within said first geodesic contour as a first mask, selecting a second geodesic contour about a boundary of said identified first region, setting a region within said second geodesic contour as a second mask, and forming a final mask from a union of said first mask and said second mask.
Type:
Grant
Filed:
March 24, 2008
Date of Patent:
April 10, 2012
Assignee:
Technion Research & Development Foundation L'
Inventors:
Michael Bronstein, Alexander Bronstein, Ron Kimmel
Abstract: A composition of matter which comprises a non-gaseous nitrogen containing compound; and a spore of a micro-organism. A method of determining a source of a material the material being an explosive or a substance used in the preparation of the explosive, the material comprises a spore of a micro-organism uniquely associated with the material, the method comprises inducing the spore to transform into a vegetative micro-organism and identifying the micro-organism as being associated with the material, thereby determining the source of the material.
Abstract: An actuator device is disclosed. The actuator device comprises a stack of piezoelectric-ferroelectric active layers separated by surface electrodes. At least a few of the surface electrodes are independently addressable such that at least two active layers are biasable by different voltages. In an embodiment of the invention, at least a few of the voltages induce a nonlinear ferroelectric effect.
Type:
Grant
Filed:
January 28, 2009
Date of Patent:
March 20, 2012
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: A nutritional Composition for a subject, comprising prolactin identical or similar or analogous to prolactin found in a natural food source, and at least one protective layer, wherein release of said prolactin from the composition in said subject is the result of an environmental event.
Type:
Application
Filed:
February 17, 2010
Publication date:
March 8, 2012
Applicant:
Technion-Research & Development Foundation Ltd
Abstract: A device of estimating a dose of ionizing radiation absorbed in an intra bone volume. The device comprises a static magnetic field source adapted to generate a substantially static magnetic field in a probing space having a volume of less than 2 cubic millimeter (mm3), the probing space being placed in front of a distal end of static magnetic field source, a micro resonator mounted in adjacent to the distal end, and at least one transmission line which feeds the resonator so as to generate an microwave magnetic field at the probing space and to transmit a signal returned from said microwave magnetic field and indicative of radiation induced paramagnetic defects in said probing space so as to allow a spectrometer to compute a dose of ionizing radiation absorbed in a portion of a bone placed in the probing space according to an analysis of the signal. The static magnetic field source being sized and shaped to maneuver the probing space to overlap with an intra bone volume of the bone.
Type:
Application
Filed:
April 15, 2010
Publication date:
February 2, 2012
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: A method of forming an image of a target that comprises illuminating a target with light, maneuvering an optical unit having at least one diffractive element in front of the target through a plurality of positions, capturing, during the maneuvering, a plurality of spectrally encoded frames each from a portion of the light that is scattered from a different of a plurality of overlapping segments along a track traversing an image plane of the target, and combining the plurality of spectrally encoded frames to form a composite multispectral image of at least a portion of said target.
Type:
Application
Filed:
July 27, 2011
Publication date:
February 2, 2012
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: A process for electroplating high adhesion copper layer on a surface of a highly oxidizable metal in an invariable container, and products produced by this process are provided.
Type:
Application
Filed:
February 11, 2010
Publication date:
February 2, 2012
Applicant:
Technion Research & Development Foundation Ltd.
Inventors:
Yair Ein-Eli, Nina Sezin, David Starosvetsky
Abstract: Articles of manufacturing, methods, devices and compositions for preventing or reducing tobacco-associated damage in a subject, and which utilize a metal ion chelating agent, a copper chelating agent, a penicillamine and/or a structural analog of penicillamine, with and without an additional antioxidant, are disclosed.
Type:
Application
Filed:
September 21, 2011
Publication date:
January 19, 2012
Applicant:
Technion Research & Development Foundation Ltd.