Abstract: A method and device for identifying a molecule in a sample, the molecule comprising an electrophilic or nucleophilic moiety. The method comprises contacting the sample with a plurality of chemosensors, each of the chemosensors comprising a ?-conjugated system and a moiety having a nucleophilic property or an electrophilic property; and measuring an electromagnetic property of each of the chemosensors in the sample; whereby the pattern of changes in the electromagnetic properties of the plurality of chemosensors after chemically reacting with the electrophile or nucleophile of the molecule identifies the molecule in said sample.

Abstract: The present invention provides compounds of the general formula I, and uses thereof for printing electronic components such as wires, resistors and LEDs.

Abstract: A method to provide direct bonding of wires to silicon for microelectronic and micro-electromechanical systems (MEMS). The method includes preparing a rough “pothole” during one of the many deep etch steps already provided in MEMS fabrication. The method also includes roughening of the smooth silicon surface in and around the rough pothole and plastically deforming a ball-bond into the rough pothole, such that the interconnection will eliminate a costly metallization layer, and thereby lower fabrication expenses and allow high temperature processing.

Abstract: A method of generating embryoid bodies is provided. The method comprising culturing undifferentiated embryonic stem cells on a three dimensional scaffold under conditions suitable for formation of embryoid bodies, thereby generating the embryoid bodies.

Abstract: The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.

Abstract: A device for replenishing ionizable material in a field ionization apparatus is disclosed. The device comprises a heatable reservoir containing the ionizable material, a field ionization electrode structure, and a channel being in fluid communication with said heatable reservoir. The heatable reservoir and the channel are designed and constructed such that when the heatable reservoir is heated to an evaporation temperature of the ionizable material, a flux of vaporized ionizable material is directed along the channel to a tip of the field ionization electrode structure.

Abstract: A method of designing a transmissive optical element for converting a profile of a light beam from a predetermined input profile to a predetermined output profile is disclosed. The method comprises: calculating a stationary function of a predetermined cost functional selected such that the stationary function satisfies a mapping condition for mapping the predetermined input profile into the predetermined output profile, thereby providing a mapping function. The method further comprises utilizing the mapping function for calculating surface properties of at least a first surface and a second surface of the transmissive optical element.

Abstract: A space variant polarization optical element for spatially manipulating polarization-dependent geometrical phases of an incident light beam. The element comprises a substrate with a plurality of zones of gratings with a continuously varying orientation. The orientation denoted by ?(x-y) is equal to half of a desired geometrical phase (DGP) modulus 2?. Each grating has a local period that is smaller than the wavelength of the incident light beam. In other embodiments of the present invention the substrate comprises a plurality of zones of gratings with a continuously varying orientation.

Abstract: An isolated composition of matter is disclosed. The composition comprises a heterogeneous population of cells seeded on a scaffold, wherein the heterogeneous population of cells comprises cardiomyocytes, endothelial cells and fibroblast cells. Pharmaceutical compositions comprising same and uses thereof are also disclosed.

Abstract: An inverted ladder circuit for a Digital to Analog Converter (DAC) having an input binary word representing an input value and an output current corresponding to a converted analog value. The inverted ladder circuit includes at least two fine resistor ladders, including at least an upper fine resistor ladder and a lower fine resistor ladder. The inverted ladder circuit also includes a coarse resistor ladder having a corresponding plurality of coarse ladder resistors, wherein the coarse resistor ladder slides upon the at least two fine resistor ladders. The inverted ladder circuit also includes a plurality of upper fine switches and a plurality of lower fine switches, wherein the switches operate in parallel according to the lower five bits of the input binary word. The plurality of fine ladder resistors are matched with the plurality of coarse ladder resistors to obtain current proportional to the input binary word. The output resistance and parasitic capacitance are reduced.

Abstract: A method for modifying a logic circuit layout to optimize circuit propagation delays for improved circuit operation is presented. The layout includes multiple logic gates connected by conductive segments. An initial layout of a physical electronic logic circuit having the plurality of logic gates is input. A respective size is determined for each of the logic gates in accordance with the initial layout and a circuit propagation delay criterion. The circuit propagation delay criterion is a joint function of properties of at least some of the logic gates and at least some of the conductive segments. A modified logic circuit layout is output. The modified logic circuit layout includes a layout of the logic gates arranged in accordance with the initial layout, where each of the logic gates is modified according to the respective determined size, thereby to obtain a modification of the logic circuit layout incorporating an optimized circuit propagation delay.

Abstract: A recombinant polypeptide and nucleic acid constructs capable of expressing the recombinant polypeptide are provided. The recombinant polypeptide comprises a chimeric polypeptide including an antigenic peptide being capable of binding a human MHC class I, a functional human ?-2 microglobulin and a functional human MHC class I heavy chain.

Abstract: An ion concentration sensor produces a signal reflective of the ion concentration within a solution. The ion concentration sensor is based on an ion sensitive transistor having a solution input, a reference input, a diffusion input, and a diffusion output. The ion sensitive transistor is connected as a pass transistor, such that the diffusion output provides an electrical signal indicating an ion concentration in a solution contacting the solution input.

Abstract: A semiconductor device which produces at least 1 W/m2 two photon emission power per area, when operating at one or more temperatures greater than 20 K.

Abstract: The invention provides ?-conjugated oligomers and polymers. The oligomers and polymers may comprise at least two ?-conjugated amino acid subunits. The oligomers and polymers may contain one or more ?-conjugated amino acid subunits that are optically, electrically or electronically active. The invention also provides optical, electronic and electric devices comprising oligomers and/or polymers having one or more ?-conjugated amino acids that are optically, electrically, or electronically active.

Abstract: An acoustic detector is described for detecting acoustic waves in a medium that can be a relatively dense medium. The detector comprises a concentrating structure provided with a lens-shaped cavity and an acoustic lens made of a dense fluid received within the cavity. A sensor is positioned at an acoustic focus distance from the acoustic lens. Sound waves propagating within the medium towards the acoustic detector are captured by the acoustic lens, concentrated through the concentrating structure, and are collected by the sensor. The acoustic detector can be applied to a vast variety of applications.

Abstract: A method of implementation of a P-system in membrane computing comprising: placing three mutually immiscible liquids into a container, such that a first of said liquids provides a barrier between the second and third liquids; providing an initial substrate to at least one of said second and third liquids; and applying a transport rule for said first liquid to allow transport of substrate between said second and said third liquid.

Abstract: A Cd1-xZnxS film material, with a high value of thermal coefficient of resistance, in the range of 1.5% to 3.7%. The Cd1-xZnxS material has excellent characteristics for use in a microbolometer-type uncooled infrared sensor. The film material can be deposited on microbolometer membranes or any other wafer for different applications. The film material can be deposited using the MOCVD technique, thermal evaporation or a different technique to form the film material over the wafer. The Cd1-xZnxS properties can be modified controlling certain deposition parameters and different annealing techniques. The process is performed at temperature compatible with CMOS technology.

Abstract: Methods of generating and expanding proliferative, multipotent connective tissue progenitor cells from adult stem cells are provided. Also provided are methods of generating functional tendon grafts in vitro and bone, cartilage and connective tissues in vivo using the isolated cell preparation of connective tissue progenitor cells.

Abstract: A new class of paromomycin-derived aminoglycosides, which exhibit efficient stop-codon mutation suppression activity, low toxicity and high selectivity towards eukaryotic cells are provided. Also provided are chemical and chemo-enzymatic processes of preparing these paromomycin-derived aminoglycosides and intermediates thereof, as well as pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders.