Abstract: The présent invention relates to cell-penetrating peptides characterized in that it comprises an amino acid séquence selected in the group consisting of X1LX2RALWX9LX3X9X4LWX9LX5X6X7X8, X1LX2LARWX9LX3X9X4LWX9LX5X6X7X8 and X1LX2ARLWX9LX3X9X4LWX9LX5X6X7X8, wherein X1 is beta-A or S, X2 is F or W, X3 is L, W, C or I, X4 is S, A, N or T, Xs is L or W, X6 is W or R, X7 is K or R, X8 is A or none, and X9 is R or S. Thèse peptides exhibit high efficiency, low toxicity and a natural tropism for lung tissues, and can be used either in simple complex with the cargo to be vectorised, or in nanoparticles comprising two layers of cell-pentrating peptides around the cargo.

Abstract: A process for the synthesis of a diene copolymer comprising at least two blocks, at least one of the blocks being composed of a diene elastomer, characterized in that it comprises a stage of 1,3-dipolar reaction of two polymers defined as being: a) a diene elastomer bearing an alkyne functional group at one or each of its chain ends, and b) a polymer bearing at least one azide functional group. This process of synthesis can be adjusted, whatever the nature of the monomers necessary to form each of the blocks of the copolymer. Each block can be synthesized with an appropriate chemistry, independently of the other block.

Abstract: The invention relates to a tire comprising a crown reinforcement formed of at least two working crown layers of reinforcing elements, and of at least one layer of circumferential reinforcing elements. According to the invention, the reinforcing elements of the said at least two working crown layers have a diameter less than 1.1 mm and satisfy the following relationships: (Fr×4 cos2 ?)/(P×0.75×Ø)<5, Fr1/(P1×sin|?1|)?1.2 Fr2/(P2×sin|?2|).

Abstract: A device is provided for monitoring an electrical accumulation battery that includes a set of cells connected in series. The device includes means for measuring a current intensity delivered by the battery; means for measuring an electrical voltage between an upstream connection point and a downstream connection point of each cell of the battery; a recorder that records a zero-current electrical voltage between the upstream connection point and the downstream connection point of each cell of the battery; and an electrical resistance estimator configured to periodically estimate an electrical resistance of each cell in the battery, between the upstream connection point and the downstream connection point.

Abstract: Disclosed is an apparatus and methodology for detecting contact within a monitored area. A piezoelectric sensor is attached to one end of a detector which is positioned for contact by passing items or individuals. The detector may correspond to a plurality of parallel, rubber calendared cables or a strip of polycarbonate resin. Body deformations induced into the detector upon contact travel to the piezoelectric sensor and are detected as strain coupled to the piezoelectric sensor. The apparatus and methodology may be employed to detect vehicular traffic along travel paths, human contact with walls or floors, manufactured product contact with delivery systems or any other physical contact by animate or inanimate objects or individuals.

Abstract: A tire pressure monitoring apparatus (10) includes a pressure transducer (14) and a valve stem (12). A support bracket (50) connects the valve stem (12) to the pressure transducer (14) and facilitates pivotal movement between the valve stem and the pressure transducer. The support bracket (50) includes a valve stem biasing member (80) that exerts a spring bias on the valve stem (12) to help maintain a selected angular position of the valve stem relative to the pressure transducer (14).

Abstract: A measurement system scans the given surface of a tire component (e.g., a brush-finished tread or buffed tire casing) to electronically measure data points corresponding to vertical and horizontal coordinates along the given surface. Associated computer processors electronically calculate the slope at a plurality of different locations by determining the degree of steepness (e.g., rise over run, angle or grade) between selected ones of the first and second coordinates and electronically comparing at least one slope-based parameter to one or more predetermined levels to determine a characterization defining one or more of surface adhesion fitness, finishing brush wear level and brush bristle placement location. Slope may be determined between every adjacent pair of data points or between selected data points (e.g., identified local maximum and minimum). The at least one-slope based parameter compared to the predetermined levels may correspond to the slopes themselves or to a calculated average slope value.

Abstract: The tool is to be used for driving fastening members into a supporting material. It comprises a cylinder (3), with a piston (5), a combustion chamber (1, 11), a cylinder head (12) bearing a fuel igniting means (36) in the chamber (1), a pin guide (9), for receiving a fastening member and the piston (5) shaft (7) and a cage (21). Return means are provided for opening the chamber (11), driving the pin guide (9) forwardly, opening and closing abutment means for the chamber (11). There are provided: one single central spring (32) for opening the chamber (11) and, on each side of the tool, one single opening and closing side chamber abutment (18, 55), integral with the chamber (11) and mobile in translation on the corresponding side of the cylinder (3).

Abstract: A method of determining relief markings on a tyre's sidewall surface includes assigning, to each pixel of a three-dimensional image of the surface, a grey-level value proportional to an elevation point corresponding to the pixel, to obtain a starting image. Using linear structuring elements of successively increasing sizes and oriented circumferentially, a series of successive morphological openings is performed iteratively on the starting surface. An image value obtained after a morphological opening using a structuring element is subtracted from an image value obtained after a morphological opening using a structuring element of an immediately lower size, to obtain a succession of images flattened by differencing. A thresholding operation is performed on the images flattened by differencing, to obtain binary images. A set-theoretic union of values of each of the binary images is performed, to obtain a final binary image in which markings appear in relief.

Abstract: The invention relates to a collapsible tyre for a vehicle, comprising at least one carcass reinforcement (5) surmounted radially from the outside by an inextensible crown reinforcement (4), itself radially on the inside of a tread (2), the said reinforcements (4, 5) each consisting of at least one layer of reinforcing elements, the said tread (2) being connected to two beads (6) by two sidewalls (8), the said beads (6) being intended to come into contact with a rim, each bead (6) comprising at least one circumferential reinforcing element (3) called a bead wire, the said bead wire (3) defining a mean line forming a substantially circular closed curve in a circumferential plane. The bead wire (3) of each bead (6) is flexible and comprises at least one concave part Pc of smaller radius Rc and of centre of curvature Cc. The invention also relates to a method of collapsing the tyre and to a use of the tyre.

Abstract: Disclosed is a tire mountable apparatus and method that includes a substrate defining a longitudinal direction, a top surface and a bottom surface. The substrate has a plurality of conductor terminals arranged in a substantially linear relationship. A first support element is located below the bottom surface of the substrate and a second support element is located above the top surface of the substrate. The plurality of conductor terminals are positioned between the first and second support elements. The substrate may be a piezoelectric device having a piezoelectric layer arranged between first and second conductive layers. The plurality of conductor terminals may be arranged in a substantially linear relationship along a line about 80° to about 100° to the longitudinal direction of the substrate, and the longitudinal direction of the substrate being substantially perpendicular to the direction of rotation of the tire.

Abstract: An inverter circuit comprises an inverter which can be configurable for controlling the supply of mains current from a grid to an electric machine in a start-up mode whereby the machine drives the prime mover for initialisation. Thereafter the same inverter is reconfigurable as part of the circuit to supply reactive power to the grid when the machine is running as a generator powered by the prime mover.

Abstract: A method for producing a high-quality barium titanyl salt includes using, as the fluids to be treated, at least two kinds of fluids, namely, a barium titanium mixed solution that is obtained by dissolving both a barium compound and a titanium compound in a solvent, a compound solution that is obtained by dissolving, in a solvent, a compound capable of deposing the barium and titanium contained in the barium-titanium mixed solution into a barium titanyl salt, and if necessary, one or more other fluids; and mixing these fluids together in a thin film fluid formed at least between two treating surfaces and to form a barium titanyl salt. The treating surfaces are so arranged as to face each other in an approachable/separable state with one of the treating surfaces and being capable of turning relatively to the other.

Abstract: The invention relates to an off-road tire comprising a composition based on at least one filler, a crosslinking system, from 50 to 80 parts by weight, per hundred parts by weight of elastomer (phr), of at least one isoprene elastomer and from 20 to 50 phr of at least one polybutadiene having a high vinyl content, the total content of isoprene elastomer and of polybutadiene having a high vinyl content being within a range varying from 85 to 100 phr.

Abstract: The invention relates to an off-road tire tread comprising a composition based on at least one filler, a crosslinking system, from 50 to 80 parts by weight, per hundred parts by weight of elastomer (phr), of at least one isoprene elastomer and from 20 to 50 phr of at least one tin-functionalized copolymer of butadiene and styrene having a low styrene content, the total content of isoprene elastomer and of tin-functionalized copolymer of butadiene and styrene having a low styrene content being within a range varying from 85 to 100 phr.

Abstract: The present invention relates to a method for the in vitro diagnosis of active tuberculosis, comprising a step of contacting lymphocytes of a patient suspected to have active tuberculosis with at least one protein of mycobacteria, said protein being an enzyme having a lipolytic activity, and a step of detecting the presence of specific activated lymphocytes.

Abstract: A peptide including the amino acids sequence X9CGYX13X14AX16X17X18MX20X21X22X23X24X25X26X27CPLCX32X33, a nucleic acid coding for the peptide, and/or a recombinant vector including the nucleic acid for the preparation of a drug intended for the treatment of cancer.

Abstract: Storage or handling device comprising at least one pair of rollers (11), the axes (rr?) of which are mutually parallel and are arranged a suitable distance (d) apart such that they can support a carcass (2) of substantially cylindrical shape of a tire that is in the process of being manufactured. The rollers (11) are mounted on a chassis (12) and are driven in rotation in the same direction (R) about their respective axes (rr?). One of the rollers (11) of said pair has a radial profile of sinusoidal overall shape comprising a succession of crests and of troughs, and the other roller of the pair has a cylindrical overall profile.

Abstract: The present invention relates to a method and tool for assisting alignment of one or more pin headers. In particular, the invention relates to a tool-assisted method of aiding alignment of one or more pin headers placed on a printed circuit board (PCB) prior to soldering, as well as to the tool itself.

Abstract: A foundation system is disclosed that is used when building a structure on expansive soils. The foundation system includes a vertical wall that prevents moisture from migrating beyond the vertical wall into the zone of influence under the foundation. The prevention of the moisture migration into the zone of influence precludes damage to the foundation and structure caused by expansive soils.