Abstract: The present invention relates to specific sphingolipids/sphingolipid derivatives as pharmaceutical compositions as well as their use in the preparation of medicaments for the treatment, prevention and/or amelioration of disorders relating to pathological processes in lipid rafts.

Abstract: The present invention relates a method for producing clathrate compounds, comprising producing a homogeneous melt containing the desired elements in the desired ratio, and subsequently solidifying said melt to obtain the clathrate compound by quickly cooling the melt.

Abstract: The invention relates, inter alia, to a method for the production of a ceramic shaped body (22), comprising the following steps: production or provision of a green body (10) having a structured surface region (12), irradiation of at least the structured surface region (12), so that the green body (10) is consolidated in the region of a volume zone (16) including the structured surface region (12), but is not consolidated or is consolidated to only a lesser degree in volume zones further from the surface, separation of the consolidated volume zone (16) including the structured surface region (12) from parts of the green body (10) which have not been consolidated or have been consolidated to only a lesser degree, and optionally scouring of the consolidated volume zone (16) obtained in this way.

Abstract: The present invention relates to a method for stimulating expression of peptide hormones in peptide-hormone secreting endocrine cells or neurons comprising the step of promoting in said cells or neurons the presence or activity (aa) of (i) ICA512; or (ii) a derivative thereof having ICA512 function; or (iii) a fragment of ICA512 that may be cleaved by ?-calpain giving rise to a C-terminal fragment of ICA512 wherein said C-terminal fragment has the capability of being targeted to the nucleus; or (iv) a derivative of said fragment of (iii) that may be cleaved by ?-calpain giving rise to a derivative of said C-terminal fragment of ICA512 wherein said derivative of said C-terminal fragment has the capability of being targeted to the nucleus; or (v) a fragment or derivative of ICA512 that may be cleaved by ?-calpain giving rise to a C-terminal fragment of ICA512 or derivative thereof wherein said C-terminal fragment or derivative thereof has the capability of interacting with a PIAS protein in said cells or neuron

Abstract: The invention relates to a method for distributed, fault-tolerant clock pulse generation in hardware systems, wherein the system clock pulse is generated in distribution by a plurality of intercommunicating fault-tolerant clock pulse synchronization algorithms (TS-Algs), in which an arbitrary number of such TS-Algs exchange information between one another via a user-defined and permanent network (TS-Net) of clock pulse signals, susceptible to transient faults, and each TS-Alg is assigned to one or more functional units (Fu1, Fu2, . . . ), whose local clock pulses are generated by it, and further all local clock pulses are synchronized with respect to frequency in an assured manner, and a specified number of transient and/or permanent faults may occur in the TS-Algs or in the TS-Net, without adversely affecting the clock pulse generation and/or the synchronization accuracy, and the system clock pulse automatically achieves the maximum possible frequency. The invention further relates to such a hardware system.

Abstract: A method for structuring of silicon substrates for microsystem technological device elements, wherein the silicon substrate is covered with an etching mask and wherein the structures are furnished with a predetermined etching profile in the micrometer region with side walls and an etching depth At. For the generation of a predetermined positive etching profile, the side walls of the structures are furnished with the defined slope angle ? of from 60 degrees to 88 degrees relative to the etching bottom and the structures are generated with an etching depth At in the micrometer region. Initially an isotropic etching is performed such that a mask under etching u is generated, wherein the mask under etching u is formed approximately equal to the etching depth At.

Abstract: The invention relates to methods for the production of polymer carrier materials for solid phase synthesis, particularly for peptide synthesis. (Meth)acrylamide derivatives based on carbon hydrates, which can also contain other protective groups, are polymerized by means of suspension polymerization in an aqueous phase, optionally with the addition of pore-forming additives, and subsequently the protective groups are fully or partially cleaved. It is thus possible to obtain polymer carriers whose morphology (particle size, porosity), degree of cross-linking and swelling capability in aqueous and organic media can be adjusted in a targeted manner and whose reactive groups offer multiple opportunities for the immobilization of anchor groups and protective groups. The hydroxyl groups of the polymer carrier can be activated according to usual methods of solid phase synthesis.

Abstract: The invention relates to polymerizable compositions which comprise 10-80% by weight of a reactive diluent based on acrylic acid or methacrylic acid derivatives, and 10-50% by weight of a monomer of the indicated chemical formula which is liquid or which can be dissolved in the formulation. The formula may contain amino acid residues or peptide sequences, especially such that are specific of the collagen. These structural elements allow the enzymatic degradation of the polymers of the inventive composition.

Abstract: The present invention relates to the use of specific steroid derivatives in the preparation of medicaments for the treatment or prevention and/or amelioration of disorders relating to pathological processes in lipid rafts.

Abstract: The invention relates to a method and arrangement for the contactless determination of conductivity-influencing properties and their spatial distribution over the entire cross section of an electrically conductive substance moving in a primary magnetic field (B). The substance may be a liquid or a solid. A simultaneous measurement of a number of mechanical state parameters of the magnetic system is performed (three-dimensional components of the force and the torque), said parameters being variable by the effect of a secondary field on the magnetic system, the secondary field being produced on the basis of eddy currents induced in the substance by the primary field (B). To determine the spatial distribution of the property that is sought, the primary field is changed in intensity or form a number of times and a measurement of the state parameters is carried out for each change.

Abstract: A hybrid optical network comprising a single channel optical ring network with a plurality of ring nodes and a star subnetwork. The star subnetwork comprises a central wavelength router, a plurality of combiners being connected to input ports of the central wavelength router, and a subset of the ring nodes of the ring network, each node of the subset including a tunable transmitter and a tunable receiver to communicate optical data packets over the star subnetwork. Optical data packets routed between two ring nodes of the subset over the star subnetwork are assigned a specific wavelength that determines the routing of the data packets through the central wavelength router. The invention further regards a method of routing data packets between a source ring node and a destination ring node of a hybrid optical network.

Abstract: Method for transferring storage data of a virtual machine to be migrated from a first host device to a second host device via a communication network, including: running the virtual machine on the first host device; storing, on a local storage device of the first host device, a disk image used by the virtual machine; detecting, while the virtual machine is running on the first host device, any changes made to the disk image used by the virtual machine; establishing a connection over the communication network from the first host device to the second host device; transferring, to the second host device while the virtual machine is running on the first host device, the disk image used by the virtual machine and the detected any changes made; modifying the disk image transferred to the second host device in response to the detected any changes transferred to the second host device; and starting, using the modified disk image, a migrated virtual machine on the second host device at a current state of the virtual m

Abstract: The invention relates to a method and a device for determining the parameters of a fluctuating flow of a fluid in a pipe, wherein at least three electrodes that are placed at a distance from one another in the direction of flow are provided in the periphery of the flow, wherein alternating voltage signals are fed to a first upstream transmission electrode arrangement and to a second downstream transmission electrode arrangement and the receiving signals generated by the displacement current are detected in a receiving electrode arrangement located between the transmission electrodes and subjected to a time-discrete cross-correlation. The throughput times of the fluctuations detected by the electrodes are determined on the basis of the results.

Abstract: A multichip circuit module includes a main board, at least one carrier substrate mounted on and in electrical contact with the main board, and at least one semiconductor chip arranged on the carrier substrate and in electrical contact therewith. The carrier substrate has at least one cavity on an assembly surface for receiving the semiconductor chip. The cavity includes connecting contacts which join with associated bumps on the semiconductor chip using a flip-chip technique. The assembly surface of the carrier substrate is placed on a contact surface of the main board, and a filling material is provided between the contract surface of the main board and the assembly surface of the carrier substrate.

Abstract: The invention relates to a driving agent vacuum pump used in microsystems technology, comprising an evaporator chamber and a pump chamber that are separated by a jet arrangement. The design of the driving agent vacuum pump is improved by: a planar arrangement of at least one jet, which extends vertically in depth and which is situated between two, in particular, parallel plates, these plates closing the evaporator chamber and the pump chamber; an opening in the pump chamber, preferably above the jet arrangement, for drawing in a medium to be pumped, and; an opening for expelling a preferably compressed gas underneath the jet arrangement.

Abstract: The invention relates to a method for producing a composite material, to a composite material produced according to said method and to the use of said material.

Abstract: In a device for conveying and positioning structural elements at a conveying track, a structural element is brought into pending state at the conveying track and the conveying track is tilted in conveying direction so that the structural element slides downwards to approach a target point. The position of the structural element is detected. The device further includes a control unit wherein the position of the structural element is detected within a predetermined range of the target point to be reached, and a time, at which the conveying track is tilted and re-tilted at a predetermined angular speed by a predetermined angle, is determined by using a calculation and control algorithm, so that the structural element is intercepted.

Abstract: The present invention relates to oligonucleotides directed against a survivin gene and variants thereof and to the use of said oligonucleotides in the diagnosis, prophylaxis, reduction and follow-up of diseases associated with cell growth, differentiation and/or division, such as tumor diseases.

Abstract: The present invention is directed to an implant for total hip joint replacement and a method for manufacturing such implant. In particular, the present invention relates to improved acetabular liners, total hip prosthetic assemblies comprising such liners and methods for manufacturing such liners.

Abstract: The invention relates to a liquid distribution unit (10, 20) for dividing a liquid current into a plurality of partial currents. Said unit comprises at least one liquid inlet (13, 23) for the supplied liquid current, a plurality of liquid outlets (14; 24) for the partial currents, and a plurality of channels (15, 25) connecting the liquid inlets (13, 23) to the liquid outlets (14, 24). Said unit is characterised in that the channels (15, 25) symmetrically and respectively branch off (16, 26) into upstream channels (15a, 15b, 15c, 15d, 15c; 25a, 25b, 25c, 25d, 25c) and each connection leading from the liquid inlet (13; 23 ) to one of the liquid outlets (14; 24) comprises the same channels (15, 25) and the same branches (16, 26). A liquid distribution device for the divided distributiion of at least two different liquids; comprises a plurality of such liquid distribution units (10, 20) placed flatly on top of each other.