Abstract: The invention relates to a medical analysis device (1) for assessing a patient's suitability for anaesthesia by analysing at least one physiological biosignal (S) detected during an apnoea, wherein the medical analysis device (1) comprises the following: —an input interface (2) for detecting a time curve of at least one physiological biosignal (S) of a patient, —a computing unit (3) which is configured to compare a time curve of the at least one physiological biosignal (S) with at least one predefinable curve or a limit value according to an algorithm (4) in order to determine a patient's suitability for anaesthesia and to calculate an assessment result (E) depending thereon, wherein the time curve of the at least one physiological biosignal (S) comprises at least the duration of a patient's apnoea, and —an output interface (5) connected to the computing unit (3), to output the assessment result.

Abstract: A sensing arrangement and corresponding detector device includes a sensing area, for accommodating a sensing substance selected for experimenting an optical response as a response of an external stimulus; a light emitter, for emitting light towards said sensing area; a light receiver, for receiving a light from said sensing area; a substrate having a first substrate surface and a second substrate surface; wherein, said light emitter includes a first LED and the light receiver includes a second LED, both LEDs formed on the first substrate surface; and the sensing arrangement further includes a trench, formed between the first LED and the second LED.

Abstract: A method for aligning the positions and orientations of a real object and a virtual object in real space, the virtual object corresponding to a virtual replica of the real object, the method comprising visualizing at least one alignment feature superimposed on or replacing a representation of the virtual object in a field of view containing the real object, wherein the alignment feature is indicative of a position and orientation of the virtual object in real space, and wherein the at least one alignment feature complements a shape and/or surface pattern of the real object, such that the alignment feature and the real object form a composite object with complementing patterns and/or shapes in the field of view, when the real object and the virtual object are aligned.

Abstract: The present invention relates to the use of a porous polymer etched ion-track membrane as separator for batteries comprising a positive electrode, a negative electrode and a liquid electrolyte comprising at least one salt of a cationic ion in solution in a solvent, and to batteries comprising such a membrane as porous separator.

Abstract: The present invention relates to a sigma-delta analogue-to-digital converter. The sigma-delta analogue-to-digital converter comprises a transconductance stage having first, second and third terminals. A capacitor is connected in parallel at the third terminal. Further, the sigma-delta analogue-to-digital converter comprises a quantiser at the third terminal of the transconductance stage with feedback by a voltage digital-to-analogue converter for feeding back a feedback signal to one of the terminals of the transconductance stage.

Abstract: The present invention relates to a cluster of differentiation 98 heavy chain (CD98hc)-specific binding protein, wherein the CD98hc-specific binding protein is a lipocalin 2 (Lcn2)-derived binding protein and binds to CD98hc with a KD of 200 nM or lower.

Abstract: The invention relates to a method for diagnosing a tumour disease in an isolated sample, comprising the amplification of methylated DNA sequences, to a kit for diagnosing a tumour disease, and to the use of the method and/or of the kit for the diagnosis and/or progress control of a malignant tumour disease, in particular of prostate, breast, ovarian or colorectal carcinomas. The invention furthermore relates to a computer program product comprising risk score analysis commands for diagnosing a tumour disease, and to a data processing device.

Abstract: An electrode suitable for constructing an electrochemical double layer capacitor and/or supercapacitor is provided that includes an electrode material a metal organic framework (MOF), wherein the MOF includes an inorganic building unit including metal atoms selected from group 1 to group 12 elements, and functional groups of organic linkers including oxygen (O) and one or more atoms selected from the group comprising phosphorus (P), arsenic (As), antimony (Sb), silicon (Si), selenium (Se) and bismuth (Bi). The functional groups of the organic linkers can include phosphonate, arsonate, phosphonic acid, phosphinic acid, arsonic acids and/or arsenic acids, monoester and/or diester forms thereof. Further, the metal atoms may be selected from zinc (Zn), cadmium (Cd), copper (Cu), cobalt (Co), nickel (Ni), gold (Au) and silver (Ag). The use of the MOF as a semiconductor in semiconductor applications, a semiconductive device, such as a photovoltaic cell, including the MOF are also provided.

Abstract: The invention pertains to the technical fields of bioanalytics and agriculture, and relates to a method and to an assembly for in-ovo sexing of bird eggs. The aim of the present invention is to provide a method and an assembly by means of which in-ovo sexing of bird eggs is achieved with a stable predictive accuracy of the sex and which are simple and cost-effective. The aim is achieved using a method and an assembly in which a fertilised bird egg incubated for 3 to 9 days is irradiated with at least two light-emitting laser beam sources with different excitation waves after the shell is opened, the captured and processed fluorescence scattering spectra and Raman scattering spectra being used, as complementary spectra associated with the different excitation wavelengths, to determine a classification value, and the sex being determined by comparing the determined classification value with an intrinsically determined threshold value. The method and the assembly can be used for sexing farm poultry.

Abstract: The present invention relates to a microfluidic device (1; 8) for the production of cellular spheroids comprising at least one chamber (2; 9) comprising a fluid inlet (3) for introducing fluid into the chamber (2; 9) and a fluid outlet (4) for removing said fluid from the chamber (2, 9), wherein said at least one chamber (2; 9) comprises a base formed by a substrate (5; 10) comprising at least two recesses (6; 11) to collect a fluid comprising biological cells when the substrate (5, 10) is contacted with the fluid, wherein the size of the at least two recesses (6; 11) decreases from the fluid inlet (3) to the fluid outlet (4) of the at least one chamber (2; 9).

Abstract: The invention relates to a method and a device for producing an electrode-separator assembly for a battery cell. The method comprises the following: supplying a separator material (2) by means of a separator supply device; supplying an electrode (9; 10) by means of an electrode supply device; and producing an electrode-separator assembly by means of a joining device, the electrode (9; 10) being joined to the separator material (2) and an adhesive bond being formed between the electrode (9; 10) and the separator material (2).

Abstract: A method and an apparatus for producing a concrete component, comprising concrete and a textile reinforcement composed of a reinforcement fiber strand (28), wherein first a yarn (20) is saturated with a mineral suspension (35) and forms the at least one reinforcement fiber strand (28). According to the invention, the reinforcement fiber strand (28) is fed by means of a moving device, so that the reinforcement fiber strand (28) is placed in a concrete strand (4), placed on a concrete layer (2), or placed on a vertical side surface of a plurality of concrete layers placed on top of each other, so that a perpendicular reinforcement is produced when arranged on the outside, and wherein the reinforcement fiber strand (28) is further enclosed by the concrete immediately upon placement or subsequently before the mineral suspension (35) has cured. The invention also relates to a reinforced concrete component (1).

Abstract: The invention relates to a hybrid process and a hybrid device for the production or thermal treatment of inorganic raw substances or materials in combination with further organic additives with the use of at least one gas burner in combination with at least one plasma burner in a furnace facility.

Abstract: Disclosed herein is a sensor chip for parallelized magnetic sensing of a plurality of samples, a system for parallelized magnetic sensing of a plurality of samples and a method for probing a plurality of samples using optically addressable solid-state spin systems. The sensor chip comprises an optically transparent substrate comprising a plurality of optically addressable solid-state spin systems arranged in a plurality of sensing regions in a surface layer below a top surface of the substrate. The sensor chip further comprises a plurality of sample sites, wherein each sample site is arranged above a respective sensing region. The sensor chip has a light guiding system configured to provide an optical path through the substrate connecting each of the sensing regions.

Abstract: A print head for additively manufacturing fiber-reinforced composite materials includes a feed channel, a heating block, a nozzle and a cutting unit. A filament of the fiber-reinforced material enters an inlet of the nozzle through the feed channel, leaves the nozzle via an outlet of the nozzle, and is deposited on a print bed. The cutting unit is located inside the heating block which has a beneficial effect on the cut and/or the shearing of the material to be printed. The invention also relates to a method in which the filament is cut and/or sheared, wherein the cutting unit performs a linear movement or rotation, or the print head per se performs a linear movement or rotation, as a result of which the filament is cut and/or sheared off.

Abstract: A Gunn diode is disclosed which comprises a first contact layer, a second contact layer, and an active layer based on a gallium nitride (GaN) semiconductor material having a base surface and a side surface non-parallel thereto. Optionally, related materials such as aluminum indium gallium nitride (AlInGaN) materials may also be used as the active layer. The first contact layer electrically contacts the side surface to form a side contact. The second contact layer forms an electrical contact for the base surface, so that a maximum of the electric field strength is formed when an electric voltage is applied between the first contact layer and the second contact layer at the side contact.

Abstract: The invention relates to a device and a method for UV antisepsis, in particular for intracorporeal in vivo UV antisepsis on the human and animal body in the event of colonization with multiresistant pathogens (MRPs) such as methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus epidermidis (MRSE). The device comprises a light emitting diode chip, LED chip, configured to emit radiation in the UVC spectral range, wherein the LED chip forms a light emitting diode, LED, with a package; a spectral filter element set up to limit the radiation emitted by the LED chip substantially to wavelengths below 235 nm; and an optical element for directional emission of the radiation emitted by the LED.

Abstract: The invention relates to an aluminum secondary battery comprising at least one positive electrode, at least one negative electrode, at least one electrolyte, and at least one additive, the electrolyte comprising at least one room temperature ionic liquid (RTIL), made of at least one organic salt and at least one first aluminum salt, and/or at least one deep eutectic solvent (DES) made of at least one organic solvent and at least one first aluminum salt, the additive containing bivalent metal cations and/or being suitable for forming bivalent metal cations.

Abstract: The invention relates to a device, a method, and a kit for separating particles of different sizes in a liquid. The invention additionally relates to applications of the device. The device and the method involve the capability of binding particles to solid phase particles with different diameters in a liquid, whereby the hydrodynamic diameter of the solid-phase particles determines whether the particles can pass through pores of a filter element, the diameter of said pores being modifiable in a controlled manner (e.g., the diameter can be increased or decreased). Thus, particles of equal size (e.g., B-cells and T-cells) of a liquid can be separated from one another with a high degree of separation efficiency, wherein the particles can be separated simply, quickly, and inexpensively. High yields can be produced, and the particles can be provided in a therapeutically applicable liquid.

Abstract: Provided herein is a method for treating a lymphoma in a subject in need thereof, comprising administering to the subject an effective amount of at least one PD-1 pathway agonist.