Patents Assigned to Tel-Aviv University Future Technology Development L.P.
-
Patent number: 8131354Abstract: A method of estimating stroke volume of the heart is described. In this method, the volume of the heart is estimated from electrical impedance data of the chest, at two different phases of the cardiac cycle. The stroke volume is estimated from the difference between the volumes estimated at the two phases.Type: GrantFiled: December 27, 2004Date of Patent: March 6, 2012Assignee: Tel Aviv University Future Technology Development L.P.Inventor: Shimon Arad (Abboud)
-
Patent number: 8088941Abstract: Novel compounds designed to allow interactions with binding sites of GSK-3 and hence are capable of inhibiting GSK-3 activity, via inhibition of substrate binding are disclosed. Further disclosed are pharmaceutical compositions including same and methods of using same in the treatment of GSK-3 mediated conditions.Type: GrantFiled: April 30, 2008Date of Patent: January 3, 2012Assignee: Tel Aviv University Future Technology Development L.P.Inventors: Hagit Eldar-Finkelman, Moshe Portnoy
-
Patent number: 8012929Abstract: Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X-Y or Y-X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.Type: GrantFiled: July 2, 2009Date of Patent: September 6, 2011Assignee: Tel Aviv University Future Technology Development L.P.Inventor: Ehud Gazit
-
Patent number: 7951511Abstract: The present invention provides a cathode and a fuel cell, which are built to prevent escape of liquids, e.g. water and fuel solution, from the cell. Thus, according to a first aspect thereof, the present invention provides a cathode suitable for use in a fuel cell having a proton conducting membrane, the cathode comprising a plurality of layers including a catalyst layer and a hydrophobic porous support layer, wherein at least one of said plurality of layers is a liquid water leak-proof layer, which allows gas to pass through it and prevents passage of liquid water and/or aqueous fuel solution.Type: GrantFiled: April 21, 2010Date of Patent: May 31, 2011Assignee: Tel-Aviv University Future Technology Development L.P.Inventors: Emanuel Peled, Tair Duvdevani, Arnon Blum, Vladimir Livshits, Adi Aharon
-
Patent number: 7907998Abstract: A method of determining an impedance of at least one lung of a patient having an implanted pacemaker that comprises first and second leads and a case, the method comprising: a) using the leads and the case to acquire at least a first and a second impedance measurement responsive to impedance of the patient's chest that are at least partially independent; and b) using the impedance measurements to determine the impedance of at least one of the lungs substantially independently of impedance of the other lung.Type: GrantFiled: September 13, 2005Date of Patent: March 15, 2011Assignee: Tel Aviv University Future Technology Development L.P.Inventor: Shimon Arad (Abboud)
-
Patent number: 7833974Abstract: Novel conjugates that are capable of inhibiting GSK-3 activity, a process of producing same, pharmaceutical compositions including same and methods of using same in the treatment of GSK-3 mediated conditions are disclosed. Methods of treating affective disorders using GSK-3 inhibitors are further disclosed.Type: GrantFiled: May 29, 2008Date of Patent: November 16, 2010Assignee: Tel Aviv University Future Technology Development L.P.Inventor: Hagit Eldar-Finkelman
-
Publication number: 20100255873Abstract: The present invention provides a cathode and a fuel cell, which are built to prevent escape of liquids, e.g. water and fuel solution, from the cell. Thus, according to a first aspect thereof, the present invention provides a cathode suitable for use in a fuel cell having a proton conducting membrane, the cathode comprising a plurality of layers including a catalyst layer and a hydrophobic porous support layer, wherein at least one of said plurality of layers is a liquid water leak-proof layer, which allows gas to pass through it and prevents passage of liquid water and/or aqueous fuel solution.Type: ApplicationFiled: April 21, 2010Publication date: October 7, 2010Applicant: TEL-AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P.Inventors: Emanuel PELED, Tair DUVDEVANI, Arnon BLUM, Vladimir LIVSHITS, Adi AHARON
-
Publication number: 20100240726Abstract: Indole derivatives, compositions including same, and methods utilizing same for the treatment of amyloid associated diseases, such as type II diabetes mellitus, Alzheimer's dementia or diseases, systemic and localized amyloidosis, and prion-related encephalopathies are provided.Type: ApplicationFiled: June 6, 2010Publication date: September 23, 2010Applicant: Tel Aviv University Future Technology Development L.P.Inventors: Ehud GAZIT, Tomer Cohen
-
Patent number: 7781396Abstract: Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X-Y or Y-X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.Type: GrantFiled: June 21, 2006Date of Patent: August 24, 2010Assignee: Tel Aviv University Future Technology Development L.P.Inventor: Ehud Gazit
-
Patent number: 7732479Abstract: Indole derivatives, compositions including same, and methods utilizing same for the treatment of amyloid associated diseases, such as type II diabetes mellitus, Alzheimer's dementia or diseases, systemic and localized amyloidosis, and prion-related encephalopathies are provided.Type: GrantFiled: August 18, 2005Date of Patent: June 8, 2010Assignee: Tel Aviv University Future Technology Development L.P.Inventors: Ehud Gazit, Tomer Cohen
-
Patent number: 7727663Abstract: The present invention provides a cathode and a fuel cell, which are built to prevent escape of liquids, e.g. water and fuel solution, from the cell. Thus, according to a first aspect thereof, the present invention provides a cathode suitable for use in a fuel cell having a proton conducting membrane, the cathode comprising a plurality of layers including a catalyst layer and a hydrophobic porous support layer, wherein at least one of said plurality of layers is a liquid water leak-proof layer, which allows gas to pass through it and prevents passage of liquid water and/or aqueous fuel solution.Type: GrantFiled: July 18, 2002Date of Patent: June 1, 2010Assignee: Tel-Aviv University Future Technology Development L.P.Inventors: Emanuel Peled, Tair Duvdevani, Arnon Blum, Vladimir Livshits, Adi Aharon
-
Publication number: 20100105608Abstract: Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X-Y or Y-X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.Type: ApplicationFiled: December 22, 2009Publication date: April 29, 2010Applicant: Tel Aviv University Future Technology Development L.P.Inventor: Ehud Gazit
-
Publication number: 20100022459Abstract: Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X—Y or Y—X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.Type: ApplicationFiled: July 2, 2009Publication date: January 28, 2010Applicant: Tel Aviv University Future Technology Development L.PInventor: Ehud Gazit
-
Patent number: 7618748Abstract: An electrical energy storage device includes a substrate having an outer surface and having a plurality of cavities communicating with the outer surface. The cavities have interior cavity surfaces. A first electrode layer is deposited at least over the interior cavity surfaces. An electrolyte separator layer is formed over the first electrode layer so as to fill the cavities and to extend over the outer surface of the planar substrate. A second electrode layer is formed over the electrolyte separator layer on the outer surface of the planar substrate.Type: GrantFiled: March 13, 2006Date of Patent: November 17, 2009Assignee: Tel Aviv University Future Technology Development L.P.Inventors: Menachem Nathan, Emanuel Peled, Diana Golodnitsky, Ela Strauss, Vladimir Yufit, Tania Ripenbein, Inna Schechtman, Svetlana Menkin
-
Publication number: 20090209041Abstract: A peptide comprising at least 5 amino acid residues and less than 15 amino acid residues, the peptide including an amino acid sequence as set forth in SEQ ID NO: 7 as well as pharmaceutical compositions, kits and methods for diagnosing and treating amyloid associated diseases.Type: ApplicationFiled: April 9, 2009Publication date: August 20, 2009Applicant: Tel Aviv University Future Technology Development L.P.Inventor: Ehud Gazit
-
Patent number: 7544374Abstract: Lipidated glycosaminoglycan particles are prepared by reacting a glycosaminoglycan with at least one lipid to cross-link the carboxylic acid groups in the glycosaiminoglycan with a primary amine in the lipid. These particles can be used to encapsulate active ingredients, such as drugs for use in the treatment of pathological conditions in an animal.Type: GrantFiled: August 9, 2002Date of Patent: June 9, 2009Assignee: Tel Aviv University Future Technology Development L.P.Inventors: Rimona Margalit, Dan Peer
-
Publication number: 20090142656Abstract: An electrical energy storage device (20,70) includes a substrate (22), which is formed so as to define a multiplicity of micro-containers separated by electrically-insulating and ion-conducting walls (32). A first plurality of anodes (A) is disposed in a first subset (24) of the micro-containers, and a second plurality of cathodes (C) is disposed in a second subset (26) of the micro-containers. The anodes and cathodes are arranged in an interlaced pattern.Type: ApplicationFiled: April 20, 2005Publication date: June 4, 2009Applicant: Tel Aviv University Future Technology Development L.P.Inventors: Menachem Nathan, Emanuel Peled, Diana Golodnitsky, Vladimir Yufit, Tania Ripenbein
-
Patent number: 7527897Abstract: An electrical energy storage device (20) includes a microchannel plate (MCP) (22) having channels (24) formed therein, the channels having surface areas. Thin films (26) are formed over the surface areas and define an anode (34,38), a cathode (34,38), and a solid electrolyte (36) disposed between the anode and the cathode.Type: GrantFiled: October 14, 2004Date of Patent: May 5, 2009Assignee: Tel Aviv University Future Technology Development L.P.Inventors: Menachem Nathan, Emanuel Peled, Diana Golodnitsky, Ela Strauss, Vladimir Yufit, Tania Ripenbein, Inna Shechtman, Svetlana Menkin
-
Publication number: 20090062180Abstract: Novel conjugates that are capable of inhibiting GSK-3 activity, a process of producing same, pharmaceutical compositions including same and methods of using same in the treatment of GSK-3 mediated conditions are disclosed. Methods of treating affective disorders using GSK-3 inhibitors are further disclosed.Type: ApplicationFiled: May 29, 2008Publication date: March 5, 2009Applicant: Tel Aviv University Future Technology Development L.P.Inventor: Hagit Eldar-Finkelman
-
Publication number: 20080312188Abstract: Novel compounds designed to allow interactions with binding sites of GSK-3 and hence are capable of inhibiting GSK-3 activity, via inhibition of substrate binding are disclosed. Further disclosed are pharmaceutical compositions including same and methods of using same in the treatment of GSK-3 mediated conditions.Type: ApplicationFiled: April 30, 2008Publication date: December 18, 2008Applicant: Tel Aviv University Future Technology Development L.P.Inventors: Hagit Eldar-Finkelman, Moshe Portnoy