Patents Assigned to TEMASEK POLYTECHNIC
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Publication number: 20160272489Abstract: The present invention relates to a solid fuel, a system and a method for generating hydrogen. The solid fuel comprises sodium borohydride, catalyst loaded fibres and a binder, wherein the catalyst loaded fibres and the binder form a scaffold structure within which the sodium borohydride is positioned. The system comprises a fuel cartridge containing the solid fuel of the present invention for generating hydrogen gas, a reactor configured to house the fuel cartridge, a tank for storing water, a pump and a liquid conduit for conveying water from the tank to the fuel cartridge housed within the reactor to induce a hydrolysis reaction of the solid fuel contained in the fuel cartridge and a controller for regulating flow of the water.Type: ApplicationFiled: October 28, 2014Publication date: September 22, 2016Applicant: Temasek PolytechnicInventors: Lei Wang, Ming Han, Yunzhong Chen, Ee Ho Gareth Tang
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Publication number: 20160109421Abstract: A sensing system for detecting a substance in a dialysate. The system includes a hydrophobic barrier capable of allowing the substance in the dialysate to equilibrate through the barrier to a gas. The system also includes a detector capable of detecting the gas and an interface disposed between the hydrophobic barrier and the detector and configured to allow transport of the gas between the hydrophobic barrier and the detector following a concentration gradient of the gas along the interface.Type: ApplicationFiled: August 24, 2015Publication date: April 21, 2016Applicant: TEMASEK POLYTECHNICInventors: Christian Gert Bluchel, Yanmei Wang, Hua Zhang, Jui Pin Er, Kim Jyh Wong
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Patent number: 9242036Abstract: There is provided a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a layer of immobilized uremic toxin-treating enzyme particles intermixed with cation exchange particles.Type: GrantFiled: June 22, 2009Date of Patent: January 26, 2016Assignee: TEMASEK POLYTECHNICInventors: Christian Gert Bluchel, Yanmei Wang, Kim Cheng Tan
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Patent number: 9138524Abstract: A sensing system for detecting a substance in a dialysate. The system includes a hydrophobic barrier capable of allowing the substance in the dialysate to equilibrate to a gas; a detector capable of detecting the gas; an interface disposed between the hydrophobic barrier and the detector and configured to allow fluid communication of the gas; and one or more delivery mechanisms capable of transporting the gas from the hydrophobic barrier to the detector. A method of detecting ammonium gas in a dialysate is also provided.Type: GrantFiled: November 8, 2012Date of Patent: September 22, 2015Assignee: Temasek PolytechnicInventors: Christian Gert Bluchel, Yanmei Wang, Hua Zhang, Jui Pin Er, Kim Jyh Wong
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Patent number: 9067017Abstract: There is provided a flow system of a dialysis device including a dialysate conduit which is capable of being in fluid communication with the peritoneal cavity of a patient's body and of being in fluid communication with a flow path, the flow path allowing dialysate to flow from a patient's body to a sorbent capable of removing contaminants within the dialysate in an outflow mode and in an inflow mode returning the dialysate substantially free of contaminants to the patient's body. The device also includes a pump for moving the dialysate along the flow path in both the outflow mode and inflow mode and a plurality of valves disposed along the flow path. There is also provided a portable dialysis device.Type: GrantFiled: June 22, 2009Date of Patent: June 30, 2015Assignee: TEMASEK POLYTECHNICInventors: Kim Cheng Tan, Christian Gert Bluchel, Lay Leng Chew, Kee Kiat Chua, Lai Ching Helen Ho, Keng Hong Lee, Liutong Lin, Weng Cheong Roy Tang, Keng Mun Yue, Kim Jyh Wong, Cheng Lam Chua
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Publication number: 20140309584Abstract: A dialysis device is provided comprising a disposable housing having a dialysate flow path along which dialysate received from a patient is subjected to contaminant removal when in operation, wherein said disposable housing comprises a storage chamber in fluid communication with the dialysate flow path for storing the dialysate therein; a controller for controlling the operation of said disposable housing; an interface means capable of operably coupling the controller and the disposable housing to enable the contaminant removal from the dialysate, and a fluid displacement means configured to move the dialysate along the dialysate flow path, wherein said fluid displacement means comprises a deformable diaphragm integrally formed with at least one wall of said storage chamber, wherein the flow path is fluidly sealed from the controller and interface means. A method of dialysis, a dialysis system and kits are also provided.Type: ApplicationFiled: November 8, 2011Publication date: October 16, 2014Applicant: Temasek PolytechnicInventors: Christian Gert Bluchel, Liutong Lin
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Publication number: 20140291218Abstract: A sensing system for detecting a substance in a dialysate. The system includes a hydrophobic barrier capable of allowing the substance in the dialysate to equilibrate to a gas; a detector capable of detecting the gas; an interface disposed between the hydrophobic barrier and the detector and configured to allow fluid communication of the gas; and one or more delivery mechanisms capable of transporting the gas from the hydrophobic barrier to the detector. A method of detecting ammonium gas in a dialysate is also provided.Type: ApplicationFiled: November 8, 2012Publication date: October 2, 2014Applicant: Temasek PolytechnicInventors: Christian Gert Bluchel, Yanmei Wang, Hua Zhang, Jui Pin Er, Kim Jyh Wong
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Publication number: 20140017761Abstract: A substrate having compounds disposed thereon for immobilizing a functional molecule, each compound having a chain including: a moiety R that is chemically coupled to the substrate, the moiety R being selected from the group consisting of an ether, ester, carbonyl, carbonate ester, thioether, disulfide, sulfinyl, sulfonyl, and carbonothioyl; and an epoxide-containing moiety that is coupled to the moiety R by a linker including at least one nucleophilic group. Methods of preparing the substrate and use of the substrate are also disclosed.Type: ApplicationFiled: September 18, 2013Publication date: January 16, 2014Applicant: TEMASEK POLYTECHNICInventors: Christian Gert BLUCHEL, Yanmei WANG
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Patent number: 8561811Abstract: A substrate having compounds disposed thereon for immobilizing a functional molecule, each compound having a chain including: a moiety R that is chemically coupled to the substrate, the moiety R being selected from the group consisting of an ether, ester, carbonyl, carbonate ester, thioether, disulfide, sulfinyl, sulfonyl, and carbonothioyl; and an epoxide-containing moiety that is coupled to the moiety R by a linker including at least one nucleophilic group. Methods of preparing the substrate and use of the substrate are also disclosed.Type: GrantFiled: March 15, 2013Date of Patent: October 22, 2013Assignee: Temasek PolytechnicInventors: Christian Gert Bluchel, Yanmei Wang
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Publication number: 20130210111Abstract: A substrate having compounds disposed thereon for immobilizing a functional molecule, each compound having a chain including: a moiety R that is chemically coupled to the substrate, the moiety R being selected from the group consisting of an ether, ester, carbonyl, carbonate ester, thioether, disulfide, sulfinyl, sulfonyl, and carbonothioyl; and an epoxide-containing moiety that is coupled to the moiety R by a linker including at least one nucleophilic group.Type: ApplicationFiled: March 15, 2013Publication date: August 15, 2013Applicant: TEMASEK POLYTECHNICInventors: Christian Gert BLUCHEL, Yanmei WANG
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Patent number: 8440441Abstract: A substrate having compounds disposed thereon for immobilizing a functional molecule, each compound having a chain comprising: a moiety R that is chemically coupled to the substrate, said moiety R being selected from the group consisting of an ether, ester, carbonyl, carbonate ester, thioether, disulfide, sulfinyl, sulfonyl, and carbonothioyl; and an epoxide-containing moiety that is coupled to the moiety R by a linker comprising at least one nucleophilic group. Methods of preparing the substrate and use of the substrate are also disclosed.Type: GrantFiled: February 18, 2011Date of Patent: May 14, 2013Assignee: Temasek PolytechnicInventors: Christian Bluchel, Yanmei Wang
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Publication number: 20130048559Abstract: A substrate having compounds disposed thereon for immobilizing a functional molecule, each compound having a chain comprising: a moiety R that is chemically coupled to the substrate, said moiety R being selected from the group consisting of an ether, ester, carbonyl, carbonate ester, thioether, disulfide, sulfinyl, sulfonyl, and carbonothioyl; and an epoxide-containing moiety that is coupled to the moiety R by a linker comprising at least one nucleophilic group. Methods of preparing the substrate and use of the substrate are also disclosed.Type: ApplicationFiled: February 18, 2011Publication date: February 28, 2013Applicant: TEMASEK POLYTECHNICInventors: Christian Bluchel, Yanmei Wang